Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
23386
Gene name Gene Name - the full gene name approved by the HGNC.
NudC domain containing 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
NUDCD3
Synonyms (NCBI Gene) Gene synonyms aliases
NudCL
Chromosome Chromosome number
7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
7p13
Summary Summary of gene provided in NCBI Entrez Gene.
The product of this gene functions to maintain the stability of dynein intermediate chain. Depletion of this gene product results in aggregation and degradation of dynein intermediate chain, mislocalization of the dynein complex from kinetochores, spindle
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT025842 hsa-miR-7-5p Microarray 19073608
MIRT049022 hsa-miR-92a-3p CLASH 23622248
MIRT045654 hsa-miR-149-5p CLASH 23622248
MIRT042837 hsa-miR-324-3p CLASH 23622248
MIRT610881 hsa-miR-548ae-3p HITS-CLIP 23824327
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 16754861, 20562859, 25036637, 28514442
GO:0005737 Component Cytoplasm IBA 21873635
GO:0005868 Component Cytoplasmic dynein complex IDA 25205765
GO:0006457 Process Protein folding IBA 21873635
GO:0051082 Function Unfolded protein binding IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
610296 22208 ENSG00000015676
Protein
UniProt ID Q8IVD9
Protein name NudC domain-containing protein 3
PDB 1WGV
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF14050 Nudc_N 8 67 N-terminal conserved domain of Nudc. Family
PF04969 CS 188 267 CS domain Domain
Sequence
METGAAELYDQALLGILQHVGNVQDFLRVLFGFLYRKTDFYRLLRHPSDRMGFPPGAAQA
LVLQVFK
TFDHMARQDDEKRRQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPVQEIEIDS
TTELDGHQEVEKVQPPGPVKEMAHGSQEAEAPGAVAGAAEVPREPPILPRIQEQFQKNPD
SYNGAVRENYTWSQDYTDLEVRVPVPKHVVKGKQVSVALSSSSIRVAMLEENGERVLMEG
KLTHKINTESSLWSLEPGKCVLVNLSK
VGEYWWNAILEGEEPIDIDKINKERSMATVDEE
EQAVLDRLTFDYHQKLQGKPQSHELKVHEMLKKGWDAEGSPFRGQRFDPAMFNISPGAVQ
F
Sequence length 361
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Metabolic Syndrome Metabolic Syndrome GWAS
Insomnia Insomnia GWAS
Schizophrenia Schizophrenia GWAS