Gene Gene information from NCBI Gene database.
Entrez ID 23386
Gene name NudC domain containing 3
Gene symbol NUDCD3
Synonyms (NCBI Gene)
NudCL
Chromosome 7
Chromosome location 7p13
Summary The product of this gene functions to maintain the stability of dynein intermediate chain. Depletion of this gene product results in aggregation and degradation of dynein intermediate chain, mislocalization of the dynein complex from kinetochores, spindle
miRNA miRNA information provided by mirtarbase database.
1064
miRTarBase ID miRNA Experiments Reference
MIRT025842 hsa-miR-7-5p Microarray 19073608
MIRT049022 hsa-miR-92a-3p CLASH 23622248
MIRT045654 hsa-miR-149-5p CLASH 23622248
MIRT042837 hsa-miR-324-3p CLASH 23622248
MIRT610881 hsa-miR-548ae-3p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
7
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 16754861, 20562859, 25036637, 28514442, 33961781
GO:0005737 Component Cytoplasm IBA
GO:0005868 Component Cytoplasmic dynein complex IDA 25205765
GO:0006457 Process Protein folding IBA
GO:0051082 Function Unfolded protein binding IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
610296 22208 ENSG00000015676
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8IVD9
Protein name NudC domain-containing protein 3
PDB 1WGV
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF14050 Nudc_N 8 67 N-terminal conserved domain of Nudc. Family
PF04969 CS 188 267 CS domain Domain
Sequence
METGAAELYDQALLGILQHVGNVQDFLRVLFGFLYRKTDFYRLLRHPSDRMGFPPGAAQA
LVLQVFK
TFDHMARQDDEKRRQELEEKIRRKEEEEAKTVSAAAAEKEPVPVPVQEIEIDS
TTELDGHQEVEKVQPPGPVKEMAHGSQEAEAPGAVAGAAEVPREPPILPRIQEQFQKNPD
SYNGAVRENYTWSQDYTDLEVRVPVPKHVVKGKQVSVALSSSSIRVAMLEENGERVLMEG
KLTHKINTESSLWSLEPGKCVLVNLSK
VGEYWWNAILEGEEPIDIDKINKERSMATVDEE
EQAVLDRLTFDYHQKLQGKPQSHELKVHEMLKKGWDAEGSPFRGQRFDPAMFNISPGAVQ
F
Sequence length 361
Interactions View interactions