SRGAP2 (SLIT-ROBO Rho GTPase activating protein 2)

Gene

• Entrez ID: 23380
• Gene name: SLIT-ROBO Rho GTPase activating protein 2
• Gene symbol: SRGAP2
• Synonyms (NCBI Gene): ARHGAP34, FNBP2, SRGAP2A, SRGAP3
• Chromosome: 1
• Chromosome location: 1q32.1
• Summary: This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting fro

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT024967	hsa-miR-214-3p	Reporter assay	21276775
MIRT025878	hsa-miR-7-5p	Sequencing	20371350
MIRT027717	hsa-miR-98-5p	Microarray	19088304
MIRT045795	hsa-miR-191-5p	CLASH	23622248
MIRT045756	hsa-miR-125a-5p	CLASH	23622248
MIRT045164	hsa-miR-186-5p	CLASH	23622248
MIRT438268	hsa-miR-29a-3p	Luciferase reporter assay	24085298
MIRT438268	hsa-miR-29a-3p	Luciferase reporter assay	24085298
MIRT707870	hsa-miR-362-3p	HITS-CLIP	21572407
MIRT707869	hsa-miR-329-3p	HITS-CLIP	21572407
MIRT707868	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT707867	hsa-miR-8485	HITS-CLIP	21572407
MIRT707866	hsa-miR-603	HITS-CLIP	21572407
MIRT707865	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT707864	hsa-miR-1228-3p	HITS-CLIP	21572407
MIRT707862	hsa-miR-3941	HITS-CLIP	21572407
MIRT707863	hsa-miR-4789-5p	HITS-CLIP	21572407
MIRT707861	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT639907	hsa-miR-6858-3p	HITS-CLIP	23824327
MIRT639906	hsa-miR-758-5p	HITS-CLIP	23824327
MIRT639905	hsa-miR-4691-3p	HITS-CLIP	23824327
MIRT639904	hsa-miR-4778-3p	HITS-CLIP	23824327
MIRT639903	hsa-miR-3194-5p	HITS-CLIP	23824327
MIRT639902	hsa-miR-323b-5p	HITS-CLIP	23824327
MIRT639901	hsa-miR-410-5p	HITS-CLIP	23824327
MIRT639900	hsa-miR-494-5p	HITS-CLIP	23824327
MIRT639899	hsa-miR-6807-5p	HITS-CLIP	23824327
MIRT520962	hsa-miR-3662	PAR-CLIP	23446348
MIRT520961	hsa-miR-5580-3p	PAR-CLIP	23446348
MIRT520960	hsa-miR-511-3p	PAR-CLIP	23446348
MIRT520959	hsa-miR-6867-5p	PAR-CLIP	23446348
MIRT520958	hsa-miR-574-5p	PAR-CLIP	23446348
MIRT496724	hsa-miR-6849-3p	PAR-CLIP	22291592
MIRT496723	hsa-miR-4662a-5p	PAR-CLIP	22291592
MIRT496722	hsa-miR-6512-3p	PAR-CLIP	22291592
MIRT496721	hsa-miR-6720-5p	PAR-CLIP	22291592
MIRT496720	hsa-miR-218-1-3p	PAR-CLIP	22291592
MIRT445238	hsa-miR-4661-3p	PAR-CLIP	22100165
MIRT445236	hsa-miR-6755-5p	PAR-CLIP	22100165
MIRT445237	hsa-miR-1298-3p	PAR-CLIP	22100165
MIRT445235	hsa-miR-204-3p	PAR-CLIP	22100165
MIRT445234	hsa-miR-4646-5p	PAR-CLIP	22100165
MIRT445233	hsa-miR-3192-5p	PAR-CLIP	22100165
MIRT445232	hsa-miR-619-5p	PAR-CLIP	22100165
MIRT445231	hsa-miR-6506-5p	PAR-CLIP	22100165
MIRT445230	hsa-miR-6804-5p	PAR-CLIP	22100165
MIRT445229	hsa-miR-4314	PAR-CLIP	22100165
MIRT445228	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT445227	hsa-miR-6834-5p	PAR-CLIP	22100165
MIRT445226	hsa-miR-1226-5p	PAR-CLIP	22100165
MIRT445225	hsa-miR-6734-5p	PAR-CLIP	22100165
MIRT445238	hsa-miR-4661-3p	PAR-CLIP	22100165
MIRT445236	hsa-miR-6755-5p	PAR-CLIP	22100165
MIRT445237	hsa-miR-1298-3p	PAR-CLIP	22100165
MIRT445235	hsa-miR-204-3p	PAR-CLIP	22100165
MIRT445234	hsa-miR-4646-5p	PAR-CLIP	22100165
MIRT445233	hsa-miR-3192-5p	PAR-CLIP	22100165
MIRT445232	hsa-miR-619-5p	PAR-CLIP	22100165
MIRT445231	hsa-miR-6506-5p	PAR-CLIP	22100165
MIRT445230	hsa-miR-6804-5p	PAR-CLIP	22100165
MIRT445229	hsa-miR-4314	PAR-CLIP	22100165
MIRT445228	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT445227	hsa-miR-6834-5p	PAR-CLIP	22100165
MIRT445226	hsa-miR-1226-5p	PAR-CLIP	22100165
MIRT445225	hsa-miR-6734-5p	PAR-CLIP	22100165
MIRT520962	hsa-miR-3662	HITS-CLIP	27418678
MIRT520960	hsa-miR-511-3p	HITS-CLIP	27418678
MIRT520960	hsa-miR-511-3p	HITS-CLIP	27418678
MIRT520958	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT520958	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT520959	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT520959	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT733324	hsa-miR-145-5p	Immunofluorescence, Immunoprecipitaion (IP), In situ hybridization, Luciferase reporter assay, Western blotting	33859759
MIRT707870	hsa-miR-362-3p	HITS-CLIP	21572407
MIRT707869	hsa-miR-329-3p	HITS-CLIP	21572407
MIRT707868	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT707867	hsa-miR-8485	HITS-CLIP	21572407
MIRT707866	hsa-miR-603	HITS-CLIP	21572407
MIRT707865	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT707864	hsa-miR-1228-3p	HITS-CLIP	21572407
MIRT707862	hsa-miR-3941	HITS-CLIP	21572407
MIRT707863	hsa-miR-4789-5p	HITS-CLIP	21572407
MIRT707861	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT639907	hsa-miR-6858-3p	HITS-CLIP	23824327
MIRT639906	hsa-miR-758-5p	HITS-CLIP	23824327
MIRT639905	hsa-miR-4691-3p	HITS-CLIP	23824327
MIRT639904	hsa-miR-4778-3p	HITS-CLIP	23824327
MIRT639903	hsa-miR-3194-5p	HITS-CLIP	23824327
MIRT639902	hsa-miR-323b-5p	HITS-CLIP	23824327
MIRT639901	hsa-miR-410-5p	HITS-CLIP	23824327
MIRT639900	hsa-miR-494-5p	HITS-CLIP	23824327
MIRT639899	hsa-miR-6807-5p	HITS-CLIP	23824327
MIRT520962	hsa-miR-3662	PAR-CLIP	23446348
MIRT520961	hsa-miR-5580-3p	PAR-CLIP	23446348
MIRT520960	hsa-miR-511-3p	PAR-CLIP	23446348
MIRT520959	hsa-miR-6867-5p	PAR-CLIP	23446348
MIRT520958	hsa-miR-574-5p	PAR-CLIP	23446348
MIRT496724	hsa-miR-6849-3p	PAR-CLIP	22291592
MIRT496723	hsa-miR-4662a-5p	PAR-CLIP	22291592
MIRT496722	hsa-miR-6512-3p	PAR-CLIP	22291592
MIRT496721	hsa-miR-6720-5p	PAR-CLIP	22291592
MIRT496720	hsa-miR-218-1-3p	PAR-CLIP	22291592
MIRT445238	hsa-miR-4661-3p	PAR-CLIP	22100165
MIRT445236	hsa-miR-6755-5p	PAR-CLIP	22100165
MIRT445237	hsa-miR-1298-3p	PAR-CLIP	22100165
MIRT445235	hsa-miR-204-3p	PAR-CLIP	22100165
MIRT445234	hsa-miR-4646-5p	PAR-CLIP	22100165
MIRT445233	hsa-miR-3192-5p	PAR-CLIP	22100165
MIRT445232	hsa-miR-619-5p	PAR-CLIP	22100165
MIRT445231	hsa-miR-6506-5p	PAR-CLIP	22100165
MIRT445230	hsa-miR-6804-5p	PAR-CLIP	22100165
MIRT445229	hsa-miR-4314	PAR-CLIP	22100165
MIRT445228	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT445227	hsa-miR-6834-5p	PAR-CLIP	22100165
MIRT445226	hsa-miR-1226-5p	PAR-CLIP	22100165
MIRT445225	hsa-miR-6734-5p	PAR-CLIP	22100165
MIRT445238	hsa-miR-4661-3p	PAR-CLIP	22100165
MIRT445236	hsa-miR-6755-5p	PAR-CLIP	22100165
MIRT445237	hsa-miR-1298-3p	PAR-CLIP	22100165
MIRT445235	hsa-miR-204-3p	PAR-CLIP	22100165
MIRT445234	hsa-miR-4646-5p	PAR-CLIP	22100165
MIRT445233	hsa-miR-3192-5p	PAR-CLIP	22100165
MIRT445232	hsa-miR-619-5p	PAR-CLIP	22100165
MIRT445231	hsa-miR-6506-5p	PAR-CLIP	22100165
MIRT445230	hsa-miR-6804-5p	PAR-CLIP	22100165
MIRT445229	hsa-miR-4314	PAR-CLIP	22100165
MIRT445228	hsa-miR-526b-5p	PAR-CLIP	22100165
MIRT445227	hsa-miR-6834-5p	PAR-CLIP	22100165
MIRT445226	hsa-miR-1226-5p	PAR-CLIP	22100165
MIRT445225	hsa-miR-6734-5p	PAR-CLIP	22100165
MIRT755964	hsa-miR-29b-3p	Luciferase reporter assay, Western blotting, qRT-PCR, in vitro cullelar assays, ELISA	36277474
MIRT1388800	hsa-miR-106a	CLIP-seq
MIRT1388801	hsa-miR-106b	CLIP-seq
MIRT1388802	hsa-miR-1305	CLIP-seq
MIRT1388803	hsa-miR-130a	CLIP-seq
MIRT1388804	hsa-miR-130b	CLIP-seq
MIRT1388805	hsa-miR-145	CLIP-seq
MIRT1388806	hsa-miR-17	CLIP-seq
MIRT1388807	hsa-miR-19a	CLIP-seq
MIRT1388808	hsa-miR-19b	CLIP-seq
MIRT1388809	hsa-miR-20a	CLIP-seq
MIRT1388810	hsa-miR-20b	CLIP-seq
MIRT1388811	hsa-miR-2467-5p	CLIP-seq
MIRT1388812	hsa-miR-298	CLIP-seq
MIRT1388813	hsa-miR-301a	CLIP-seq
MIRT1388814	hsa-miR-301b	CLIP-seq
MIRT1388815	hsa-miR-3127-5p	CLIP-seq
MIRT1388816	hsa-miR-3188	CLIP-seq
MIRT1388817	hsa-miR-3646	CLIP-seq
MIRT1388818	hsa-miR-3666	CLIP-seq
MIRT1388819	hsa-miR-3667-3p	CLIP-seq
MIRT1388820	hsa-miR-3928	CLIP-seq
MIRT1388821	hsa-miR-3973	CLIP-seq
MIRT1388822	hsa-miR-3975	CLIP-seq
MIRT1388823	hsa-miR-4264	CLIP-seq
MIRT1388824	hsa-miR-4279	CLIP-seq
MIRT1388825	hsa-miR-4295	CLIP-seq
MIRT1388826	hsa-miR-4300	CLIP-seq
MIRT1388827	hsa-miR-4302	CLIP-seq
MIRT1388828	hsa-miR-4316	CLIP-seq
MIRT1388829	hsa-miR-4436b-3p	CLIP-seq
MIRT1388830	hsa-miR-4455	CLIP-seq
MIRT1388831	hsa-miR-4468	CLIP-seq
MIRT1388832	hsa-miR-4505	CLIP-seq
MIRT1388833	hsa-miR-454	CLIP-seq
MIRT1388834	hsa-miR-4633-3p	CLIP-seq
MIRT1388835	hsa-miR-4643	CLIP-seq
MIRT1388836	hsa-miR-4684-3p	CLIP-seq
MIRT1388837	hsa-miR-4710	CLIP-seq
MIRT1388838	hsa-miR-4717-5p	CLIP-seq
MIRT1388839	hsa-miR-4797-3p	CLIP-seq
MIRT1388840	hsa-miR-485-5p	CLIP-seq
MIRT1388841	hsa-miR-519a	CLIP-seq
MIRT1388842	hsa-miR-519b-3p	CLIP-seq
MIRT1388843	hsa-miR-519c-3p	CLIP-seq
MIRT1388844	hsa-miR-519d	CLIP-seq
MIRT1388845	hsa-miR-520g	CLIP-seq
MIRT1388846	hsa-miR-520h	CLIP-seq
MIRT1388847	hsa-miR-607	CLIP-seq
MIRT1388848	hsa-miR-609	CLIP-seq
MIRT1388849	hsa-miR-642b	CLIP-seq
MIRT1388850	hsa-miR-920	CLIP-seq
MIRT1388851	hsa-miR-93	CLIP-seq
MIRT1388852	hsa-miR-939	CLIP-seq
MIRT1388853	hsa-miR-1225-5p	CLIP-seq
MIRT1388854	hsa-miR-185	CLIP-seq
MIRT1388855	hsa-miR-2052	CLIP-seq
MIRT1388856	hsa-miR-31	CLIP-seq
MIRT1388857	hsa-miR-3135b	CLIP-seq
MIRT1388858	hsa-miR-3150b-3p	CLIP-seq
MIRT1388859	hsa-miR-335	CLIP-seq
MIRT1388860	hsa-miR-3591-3p	CLIP-seq
MIRT1388861	hsa-miR-383	CLIP-seq
MIRT1388862	hsa-miR-4306	CLIP-seq
MIRT1388863	hsa-miR-4328	CLIP-seq
MIRT1388864	hsa-miR-4419a	CLIP-seq
MIRT1388865	hsa-miR-4510	CLIP-seq
MIRT1388866	hsa-miR-4644	CLIP-seq
MIRT1388867	hsa-miR-4772-5p	CLIP-seq
MIRT1388868	hsa-miR-4784	CLIP-seq
MIRT1388869	hsa-miR-4802-5p	CLIP-seq
MIRT1388870	hsa-miR-488	CLIP-seq
MIRT1388871	hsa-miR-595	CLIP-seq
MIRT1388872	hsa-miR-765	CLIP-seq
MIRT1388830	hsa-miR-4455	CLIP-seq
MIRT1388836	hsa-miR-4684-3p	CLIP-seq
MIRT1388848	hsa-miR-609	CLIP-seq
MIRT1388802	hsa-miR-1305	CLIP-seq
MIRT2116559	hsa-miR-133a	CLIP-seq
MIRT2116560	hsa-miR-133b	CLIP-seq
MIRT2116561	hsa-miR-198	CLIP-seq
MIRT2116562	hsa-miR-320a	CLIP-seq
MIRT2116563	hsa-miR-320b	CLIP-seq
MIRT2116564	hsa-miR-320c	CLIP-seq
MIRT2116565	hsa-miR-320d	CLIP-seq
MIRT2116566	hsa-miR-320e	CLIP-seq
MIRT2116567	hsa-miR-325	CLIP-seq
MIRT1388821	hsa-miR-3973	CLIP-seq
MIRT1388822	hsa-miR-3975	CLIP-seq
MIRT2116568	hsa-miR-411	CLIP-seq
MIRT1388823	hsa-miR-4264	CLIP-seq
MIRT2116569	hsa-miR-4283	CLIP-seq
MIRT2116570	hsa-miR-4292	CLIP-seq
MIRT1388827	hsa-miR-4302	CLIP-seq
MIRT2116571	hsa-miR-4422	CLIP-seq
MIRT2116572	hsa-miR-4429	CLIP-seq
MIRT2116573	hsa-miR-4489	CLIP-seq
MIRT2116574	hsa-miR-4734	CLIP-seq
MIRT2116575	hsa-miR-4786-3p	CLIP-seq
MIRT1388839	hsa-miR-4797-3p	CLIP-seq
MIRT2116576	hsa-miR-520a-5p	CLIP-seq
MIRT1388845	hsa-miR-520g	CLIP-seq
MIRT1388846	hsa-miR-520h	CLIP-seq
MIRT2116577	hsa-miR-525-5p	CLIP-seq
MIRT1388847	hsa-miR-607	CLIP-seq
MIRT2116578	hsa-miR-9	CLIP-seq
MIRT2338914	hsa-miR-1231	CLIP-seq
MIRT2338915	hsa-miR-3064-5p	CLIP-seq
MIRT2338916	hsa-miR-3189-3p	CLIP-seq
MIRT2338917	hsa-miR-3663-5p	CLIP-seq
MIRT2338918	hsa-miR-3691-5p	CLIP-seq
MIRT2338919	hsa-miR-4687-3p	CLIP-seq
MIRT2338920	hsa-miR-4711-3p	CLIP-seq
MIRT2338921	hsa-miR-4752	CLIP-seq
MIRT2338922	hsa-miR-4764-5p	CLIP-seq
MIRT2338923	hsa-miR-7	CLIP-seq
MIRT2395168	hsa-miR-1293	CLIP-seq
MIRT2395169	hsa-miR-3064-3p	CLIP-seq
MIRT2395170	hsa-miR-3138	CLIP-seq
MIRT2395171	hsa-miR-4483	CLIP-seq
MIRT2395172	hsa-miR-4520a-3p	CLIP-seq
MIRT2632454	hsa-miR-1193	CLIP-seq
MIRT2632455	hsa-miR-1206	CLIP-seq
MIRT2632456	hsa-miR-1208	CLIP-seq
MIRT2632457	hsa-miR-1225-3p	CLIP-seq
MIRT2632458	hsa-miR-1233	CLIP-seq
MIRT2632459	hsa-miR-127-5p	CLIP-seq
MIRT2632460	hsa-miR-128	CLIP-seq
MIRT2632461	hsa-miR-1283	CLIP-seq
MIRT2632462	hsa-miR-1288	CLIP-seq
MIRT2632463	hsa-miR-1322	CLIP-seq
MIRT2632464	hsa-miR-138	CLIP-seq
MIRT1388805	hsa-miR-145	CLIP-seq
MIRT2632465	hsa-miR-149	CLIP-seq
MIRT2632466	hsa-miR-199a-5p	CLIP-seq
MIRT2632467	hsa-miR-199b-5p	CLIP-seq
MIRT2632468	hsa-miR-27a	CLIP-seq
MIRT2632469	hsa-miR-27b	CLIP-seq
MIRT2632470	hsa-miR-296-3p	CLIP-seq
MIRT2338915	hsa-miR-3064-5p	CLIP-seq
MIRT2632471	hsa-miR-3146	CLIP-seq
MIRT2632472	hsa-miR-3169	CLIP-seq
MIRT2632473	hsa-miR-3180-5p	CLIP-seq
MIRT2632474	hsa-miR-3184	CLIP-seq
MIRT2632475	hsa-miR-3194-3p	CLIP-seq
MIRT2632476	hsa-miR-326	CLIP-seq
MIRT2632477	hsa-miR-330-5p	CLIP-seq
MIRT2632478	hsa-miR-3661	CLIP-seq
MIRT2338917	hsa-miR-3663-5p	CLIP-seq
MIRT2632479	hsa-miR-3664-3p	CLIP-seq
MIRT2632480	hsa-miR-3670	CLIP-seq
MIRT2632481	hsa-miR-3672	CLIP-seq
MIRT2632482	hsa-miR-377	CLIP-seq
MIRT2632483	hsa-miR-3909	CLIP-seq
MIRT2632484	hsa-miR-3915	CLIP-seq
MIRT1388820	hsa-miR-3928	CLIP-seq
MIRT2632485	hsa-miR-423-5p	CLIP-seq
MIRT2632486	hsa-miR-4263	CLIP-seq
MIRT2632487	hsa-miR-4277	CLIP-seq
MIRT2632488	hsa-miR-4278	CLIP-seq
MIRT2632489	hsa-miR-4287	CLIP-seq
MIRT2632490	hsa-miR-4311	CLIP-seq
MIRT2632491	hsa-miR-433	CLIP-seq
MIRT2632492	hsa-miR-4421	CLIP-seq
MIRT2632493	hsa-miR-4436a	CLIP-seq
MIRT2632494	hsa-miR-4438	CLIP-seq
MIRT2632495	hsa-miR-4469	CLIP-seq
MIRT2632496	hsa-miR-4476	CLIP-seq
MIRT2632497	hsa-miR-4511	CLIP-seq
MIRT2632498	hsa-miR-4641	CLIP-seq
MIRT2632499	hsa-miR-4651	CLIP-seq
MIRT2632500	hsa-miR-4659a-5p	CLIP-seq
MIRT2632501	hsa-miR-4659b-5p	CLIP-seq
MIRT2632502	hsa-miR-4685-3p	CLIP-seq
MIRT2632503	hsa-miR-4716-3p	CLIP-seq
MIRT2632504	hsa-miR-4725-5p	CLIP-seq
MIRT2632505	hsa-miR-4733-3p	CLIP-seq
MIRT2632506	hsa-miR-4747-3p	CLIP-seq
MIRT2632507	hsa-miR-4786-5p	CLIP-seq
MIRT2632508	hsa-miR-4794	CLIP-seq
MIRT2632509	hsa-miR-4799-5p	CLIP-seq
MIRT1388870	hsa-miR-488	CLIP-seq
MIRT2632510	hsa-miR-504	CLIP-seq
MIRT2632511	hsa-miR-5095	CLIP-seq
MIRT2632512	hsa-miR-513a-5p	CLIP-seq
MIRT2632513	hsa-miR-539	CLIP-seq
MIRT2632514	hsa-miR-548b-3p	CLIP-seq
MIRT2632515	hsa-miR-570	CLIP-seq
MIRT2632516	hsa-miR-576-5p	CLIP-seq
MIRT2632517	hsa-miR-593	CLIP-seq
MIRT2632518	hsa-miR-608	CLIP-seq
MIRT2632519	hsa-miR-631	CLIP-seq
MIRT2632520	hsa-miR-649	CLIP-seq
MIRT2632521	hsa-miR-665	CLIP-seq
MIRT2632522	hsa-miR-759	CLIP-seq
MIRT2632523	hsa-miR-769-5p	CLIP-seq
MIRT2632454	hsa-miR-1193	CLIP-seq
MIRT2632455	hsa-miR-1206	CLIP-seq
MIRT2632456	hsa-miR-1208	CLIP-seq
MIRT2632457	hsa-miR-1225-3p	CLIP-seq
MIRT2632458	hsa-miR-1233	CLIP-seq
MIRT2632459	hsa-miR-127-5p	CLIP-seq
MIRT2632461	hsa-miR-1283	CLIP-seq
MIRT2632462	hsa-miR-1288	CLIP-seq
MIRT2632463	hsa-miR-1322	CLIP-seq
MIRT2632464	hsa-miR-138	CLIP-seq
MIRT1388805	hsa-miR-145	CLIP-seq
MIRT2632466	hsa-miR-199a-5p	CLIP-seq
MIRT2632467	hsa-miR-199b-5p	CLIP-seq
MIRT2632470	hsa-miR-296-3p	CLIP-seq
MIRT2632471	hsa-miR-3146	CLIP-seq
MIRT2632472	hsa-miR-3169	CLIP-seq
MIRT2632473	hsa-miR-3180-5p	CLIP-seq
MIRT2632474	hsa-miR-3184	CLIP-seq
MIRT2338917	hsa-miR-3663-5p	CLIP-seq
MIRT2632479	hsa-miR-3664-3p	CLIP-seq
MIRT2632481	hsa-miR-3672	CLIP-seq
MIRT2632482	hsa-miR-377	CLIP-seq
MIRT2632483	hsa-miR-3909	CLIP-seq
MIRT2632484	hsa-miR-3915	CLIP-seq
MIRT1388820	hsa-miR-3928	CLIP-seq
MIRT2632485	hsa-miR-423-5p	CLIP-seq
MIRT2632486	hsa-miR-4263	CLIP-seq
MIRT2632487	hsa-miR-4277	CLIP-seq
MIRT2632488	hsa-miR-4278	CLIP-seq
MIRT2632489	hsa-miR-4287	CLIP-seq
MIRT2691956	hsa-miR-4308	CLIP-seq
MIRT2632491	hsa-miR-433	CLIP-seq
MIRT2632493	hsa-miR-4436a	CLIP-seq
MIRT2632494	hsa-miR-4438	CLIP-seq
MIRT2632495	hsa-miR-4469	CLIP-seq
MIRT2632496	hsa-miR-4476	CLIP-seq
MIRT2691957	hsa-miR-4640-5p	CLIP-seq
MIRT2632498	hsa-miR-4641	CLIP-seq
MIRT2632499	hsa-miR-4651	CLIP-seq
MIRT2632500	hsa-miR-4659a-5p	CLIP-seq
MIRT2632501	hsa-miR-4659b-5p	CLIP-seq
MIRT2632502	hsa-miR-4685-3p	CLIP-seq
MIRT2632503	hsa-miR-4716-3p	CLIP-seq
MIRT2632504	hsa-miR-4725-5p	CLIP-seq
MIRT2691958	hsa-miR-4726-5p	CLIP-seq
MIRT2632505	hsa-miR-4733-3p	CLIP-seq
MIRT2632507	hsa-miR-4786-5p	CLIP-seq
MIRT2632508	hsa-miR-4794	CLIP-seq
MIRT2632509	hsa-miR-4799-5p	CLIP-seq
MIRT2632510	hsa-miR-504	CLIP-seq
MIRT2632511	hsa-miR-5095	CLIP-seq
MIRT2632516	hsa-miR-576-5p	CLIP-seq
MIRT2632518	hsa-miR-608	CLIP-seq
MIRT2632521	hsa-miR-665	CLIP-seq
MIRT2632522	hsa-miR-759	CLIP-seq
MIRT2632523	hsa-miR-769-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003363	Process	Lamellipodium assembly involved in ameboidal cell migration	IMP	20810653
GO:0005096	Function	GTPase activator activity	IBA
GO:0005096	Function	GTPase activator activity	IDA	21148482, 27373832
GO:0005096	Function	GTPase activator activity	IEA
GO:0005096	Function	GTPase activator activity	IMP	20810653
GO:0005096	Function	GTPase activator activity	TAS
GO:0005515	Function	Protein binding	IPI	15161933, 16318909, 17500595, 19807924, 20810653, 21148482, 22559944, 26365803, 28514442, 33961781, 35271311, 36931259
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	ISS
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IDA	21148482
GO:0005886	Component	Plasma membrane	IEA
GO:0007165	Process	Signal transduction	IEA
GO:0007399	Process	Nervous system development	IBA
GO:0007399	Process	Nervous system development	IEA
GO:0014069	Component	Postsynaptic density	IEA
GO:0014069	Component	Postsynaptic density	ISS
GO:0016020	Component	Membrane	IEA
GO:0021816	Process	Extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration	IEA
GO:0021816	Process	Extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration	ISS
GO:0030027	Component	Lamellipodium	IDA	20810653
GO:0030027	Component	Lamellipodium	IEA
GO:0030334	Process	Regulation of cell migration	IEA
GO:0030336	Process	Negative regulation of cell migration	IBA
GO:0031267	Function	Small GTPase binding	IDA	20810653, 21148482
GO:0031267	Function	Small GTPase binding	IEA
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0034446	Process	Substrate adhesion-dependent cell spreading	IMP	20810653
GO:0042802	Function	Identical protein binding	IPI	20810653, 26365803
GO:0042803	Function	Protein homodimerization activity	IDA	20810653
GO:0042803	Function	Protein homodimerization activity	IEA
GO:0042995	Component	Cell projection	IEA
GO:0043197	Component	Dendritic spine	IBA
GO:0043197	Component	Dendritic spine	IEA
GO:0043197	Component	Dendritic spine	IEA
GO:0043547	Process	Positive regulation of GTPase activity	IDA	21148482, 27373832
GO:0043547	Process	Positive regulation of GTPase activity	IMP	20810653
GO:0044327	Component	Dendritic spine head	IDA	22559944
GO:0045202	Component	Synapse	IEA
GO:0045211	Component	Postsynaptic membrane	IEA
GO:0045211	Component	Postsynaptic membrane	ISS
GO:0045335	Component	Phagocytic vesicle	IEA
GO:0045335	Component	Phagocytic vesicle	ISS
GO:0046847	Process	Filopodium assembly	IDA	22559944
GO:0046847	Process	Filopodium assembly	IEA
GO:0048812	Process	Neuron projection morphogenesis	IEA
GO:0048812	Process	Neuron projection morphogenesis	ISS
GO:0051014	Process	Actin filament severing	IDA	21148482
GO:0051056	Process	Regulation of small GTPase mediated signal transduction	TAS
GO:0051963	Process	Regulation of synapse assembly	IBA
GO:0051963	Process	Regulation of synapse assembly	IEA
GO:0060996	Process	Dendritic spine development	IDA	22559944
GO:0060996	Process	Dendritic spine development	IEA
GO:0098978	Component	Glutamatergic synapse	IBA
GO:0098978	Component	Glutamatergic synapse	IEA
GO:1904861	Process	Excitatory synapse assembly	IDA	27373832
GO:1904861	Process	Excitatory synapse assembly	IEA
GO:1904862	Process	Inhibitory synapse assembly	IDA	27373832
GO:1904862	Process	Inhibitory synapse assembly	IEA
GO:2001223	Process	Negative regulation of neuron migration	IDA	22559944

Other IDs

• MIM: 606524
• HGNC: 19751
• e!Ensembl: ENSG00000266028

Protein

• UniProt ID: O75044
• Protein name: SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2) (Formin-binding protein 2) (Rho GTPase-activating protein 34)
• Protein function: Postsynaptic RAC1 GTPase activating protein (GAP) that plays a key role in neuronal morphogenesis and migration mainly during development of the cerebral cortex (PubMed:20810653, PubMed:27373832, PubMed:28333212). Regulates excitatory and inhibi
• PDB: 2DL8, 4RTT, 4RUG, 5I6J, 5I6R, 5I7D
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00611	FCH	31 → 115	Fes/CIP4, and EFC/F-BAR homology domain	Family
  PF00620	RhoGAP	505 → 657	RhoGAP domain	Domain
  PF00018	SH3_1	734 → 779	SH3 domain	Domain

• Sequence:

  MTSPAKFKKDKEIIAEYDTQVKEIRAQLTEQMKCLDQQCELRVQLLQDLQDFFRKKAEIE
  MDYSRNLEKLAERFLAKTRSTKDQQFKKDQNVLSPVNCWNLLLNQVKRESRDHTTLSDIY
  LNNIIPRFVQVSEDSGRLFKKSKEVGQQLQDDLMKVLNELYSVMKTYHMYNADSISAQSK
  LKEAEKQEEKQIGKSVKQEDRQTPRSPDSTANVRIEEKHVRRSSVKKIEKMKEKRQAKYT
  ENKLKAIKARNEYLLALEATNASVFKYYIHDLSDLIDQCCDLGYHASLNRALRTFLSAEL
  NLEQSKHEGLDAIENAVENLDATSDKQRLMEMYNNVFCPPMKFEFQPHMGDMASQLCAQQ
  PVQSELVQRCQQLQSRLSTLKIENEEVKKTMEATLQTIQDIVTVEDFDVSDCFQYSNSME
  SVKSTVSETFMSKPSIAKRRANQQETEQFYFTKMKEYLEGRNLITKLQAKHDLLQKTLGE
  SQRTDCSLARRSSTVRKQDSSQAIPLVVESCIRFISRHGLQHEGIFRVSGSQVEVNDIKN
  AFERGEDPLAGDQNDHDMDSIAGVLKLYFRGLEHPLFPKDIFHDLMACVTMDNLQERALH
  IRKVLLVLPKTTLIIMRYLFAFLNHLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSC
  QAHVNELIKTIIIQHENIFPSPRELEGPVYSRGGSMEDYCDSPHGETTSVEDSTQDVTAE
  HHTSDDECEPIEAIAKFDYVGRTARELSFKKGASLLLYQRASDDWWEGRHNGIDGLIPHQ
  YIVVQDTEDGVVERSSPKSEIEVISEPPEEKVTARAGASCPSGGHVADIYLANINKQRKR
  PESGSIRKTFRSDSHGLSSSLTDSSSPGVGASCRPSSQPIMSQSLPKEGPDKCSISGHGS
  LNSISRHSSLKNRLDSPQIRKTATAGRSKSFNNHRPMDPEVIAQDIEATMNSALNELREL
  ERQSSVKHTPDVVLDTLEPLKTSPVVAPTSEPSSPLHTQLLKDPEPAFQRSASTAGDIAC
  AFRPVKSVKMAAPVKPPATRPKPTVFPKTNATSPGVNSSTSPQSTDKSCTV

• Sequence length: 1071

Pathways

KEGG:

Axon guidance

Reactome:

Rho GTPase cycle
RHO GTPases Activate Formins

Associated diseases

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Intellectual disability	Uncertain significance	rs2987927	RCV000578222
SRGAP2-associated Neurodevelopmental Disorder	Uncertain significance	rs782657746	RCV002266864

Associations from Text Mining
Disease Name	Relationship Type	References
Breast Neoplasms	Associate	21738711
Diabetic Nephropathies	Inhibit	37952894
Dyslipidemias	Associate	28912560
Pancreatic Neoplasms	Associate	36277474