Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	23373
Gene name Gene Name - the full gene name approved by the HGNC.	CREB regulated transcription coactivator 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	CRTC1
Synonyms (NCBI Gene) Gene synonyms aliases	MAML2, MECT1, Mam-2, TORC-1, TORC1, WAMTP1
Chromosome Chromosome number	19
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	19p13.11

Show/Hide all(296)

miRTarBase ID	miRNA	Experiments	Reference
MIRT045900	hsa-miR-125b-5p	CLASH	23622248
MIRT718115	hsa-miR-1470	HITS-CLIP	19536157
MIRT718114	hsa-miR-4667-3p	HITS-CLIP	19536157
MIRT718113	hsa-miR-5193	HITS-CLIP	19536157
MIRT718111	hsa-miR-3183	HITS-CLIP	19536157
MIRT718112	hsa-miR-4723-3p	HITS-CLIP	19536157
MIRT718110	hsa-miR-6769b-3p	HITS-CLIP	19536157
MIRT718109	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT718108	hsa-miR-6134	HITS-CLIP	19536157
MIRT718107	hsa-miR-324-5p	HITS-CLIP	19536157
MIRT718106	hsa-miR-3945	HITS-CLIP	19536157
MIRT718105	hsa-miR-4253	HITS-CLIP	19536157
MIRT718104	hsa-miR-6862-5p	HITS-CLIP	19536157
MIRT718103	hsa-miR-541-3p	HITS-CLIP	19536157
MIRT718102	hsa-miR-654-5p	HITS-CLIP	19536157
MIRT718101	hsa-miR-7111-3p	HITS-CLIP	19536157
MIRT540392	hsa-miR-3667-5p	PAR-CLIP	21572407
MIRT540393	hsa-miR-3120-3p	PAR-CLIP	21572407
MIRT540391	hsa-miR-451b	PAR-CLIP	21572407
MIRT540390	hsa-miR-3675-3p	PAR-CLIP	21572407
MIRT540389	hsa-miR-520f-5p	PAR-CLIP	21572407
MIRT540388	hsa-miR-4696	PAR-CLIP	21572407
MIRT507624	hsa-miR-212-3p	PAR-CLIP	23446348
MIRT507623	hsa-miR-132-3p	PAR-CLIP	23446348
MIRT507622	hsa-miR-4787-3p	PAR-CLIP	23446348
MIRT507621	hsa-miR-4638-3p	PAR-CLIP	23446348
MIRT540393	hsa-miR-3120-3p	PAR-CLIP	27292025
MIRT540393	hsa-miR-3120-3p	PAR-CLIP	27292025
MIRT540393	hsa-miR-3120-3p	PAR-CLIP	27292025
MIRT540392	hsa-miR-3667-5p	PAR-CLIP	27292025
MIRT540392	hsa-miR-3667-5p	PAR-CLIP	27292025
MIRT540392	hsa-miR-3667-5p	PAR-CLIP	27292025
MIRT540390	hsa-miR-3675-3p	PAR-CLIP	27292025
MIRT540390	hsa-miR-3675-3p	PAR-CLIP	27292025
MIRT540390	hsa-miR-3675-3p	PAR-CLIP	27292025
MIRT540391	hsa-miR-451b	PAR-CLIP	27292025
MIRT540391	hsa-miR-451b	PAR-CLIP	27292025
MIRT540391	hsa-miR-451b	PAR-CLIP	27292025
MIRT540388	hsa-miR-4696	PAR-CLIP	27292025
MIRT540388	hsa-miR-4696	PAR-CLIP	27292025
MIRT540388	hsa-miR-4696	PAR-CLIP	27292025
MIRT540389	hsa-miR-520f-5p	PAR-CLIP	27292025
MIRT540389	hsa-miR-520f-5p	PAR-CLIP	27292025
MIRT540389	hsa-miR-520f-5p	PAR-CLIP	27292025
MIRT718115	hsa-miR-1470	HITS-CLIP	19536157
MIRT718114	hsa-miR-4667-3p	HITS-CLIP	19536157
MIRT718113	hsa-miR-5193	HITS-CLIP	19536157
MIRT718111	hsa-miR-3183	HITS-CLIP	19536157
MIRT718112	hsa-miR-4723-3p	HITS-CLIP	19536157
MIRT718110	hsa-miR-6769b-3p	HITS-CLIP	19536157
MIRT718109	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT718108	hsa-miR-6134	HITS-CLIP	19536157
MIRT718107	hsa-miR-324-5p	HITS-CLIP	19536157
MIRT718106	hsa-miR-3945	HITS-CLIP	19536157
MIRT718105	hsa-miR-4253	HITS-CLIP	19536157
MIRT718104	hsa-miR-6862-5p	HITS-CLIP	19536157
MIRT718103	hsa-miR-541-3p	HITS-CLIP	19536157
MIRT718102	hsa-miR-654-5p	HITS-CLIP	19536157
MIRT718101	hsa-miR-7111-3p	HITS-CLIP	19536157
MIRT540392	hsa-miR-3667-5p	PAR-CLIP	21572407
MIRT540393	hsa-miR-3120-3p	PAR-CLIP	21572407
MIRT540391	hsa-miR-451b	PAR-CLIP	21572407
MIRT540390	hsa-miR-3675-3p	PAR-CLIP	21572407
MIRT540389	hsa-miR-520f-5p	PAR-CLIP	21572407
MIRT540388	hsa-miR-4696	PAR-CLIP	21572407
MIRT507624	hsa-miR-212-3p	PAR-CLIP	23446348
MIRT507623	hsa-miR-132-3p	PAR-CLIP	23446348
MIRT507622	hsa-miR-4787-3p	PAR-CLIP	23446348
MIRT507621	hsa-miR-4638-3p	PAR-CLIP	23446348
MIRT910738	hsa-miR-1248	CLIP-seq
MIRT910739	hsa-miR-1289	CLIP-seq
MIRT910740	hsa-miR-129-3p	CLIP-seq
MIRT910741	hsa-miR-2052	CLIP-seq
MIRT910742	hsa-miR-3192	CLIP-seq
MIRT910743	hsa-miR-3194-5p	CLIP-seq
MIRT910744	hsa-miR-326	CLIP-seq
MIRT910745	hsa-miR-330-5p	CLIP-seq
MIRT910746	hsa-miR-4269	CLIP-seq
MIRT910747	hsa-miR-4284	CLIP-seq
MIRT910748	hsa-miR-4297	CLIP-seq
MIRT910749	hsa-miR-4314	CLIP-seq
MIRT910750	hsa-miR-4433	CLIP-seq
MIRT910751	hsa-miR-4639-3p	CLIP-seq
MIRT910752	hsa-miR-4646-5p	CLIP-seq
MIRT910753	hsa-miR-4684-5p	CLIP-seq
MIRT910754	hsa-miR-4690-5p	CLIP-seq
MIRT910755	hsa-miR-4773	CLIP-seq
MIRT910756	hsa-miR-4786-5p	CLIP-seq
MIRT910757	hsa-miR-532-5p	CLIP-seq
MIRT910758	hsa-miR-570	CLIP-seq
MIRT910759	hsa-miR-665	CLIP-seq
MIRT910760	hsa-miR-922	CLIP-seq
MIRT910761	hsa-miR-1227	CLIP-seq
MIRT910762	hsa-miR-125a-5p	CLIP-seq
MIRT910763	hsa-miR-125b	CLIP-seq
MIRT910764	hsa-miR-1275	CLIP-seq
MIRT910765	hsa-miR-1281	CLIP-seq
MIRT910766	hsa-miR-1285	CLIP-seq
MIRT910767	hsa-miR-1291	CLIP-seq
MIRT910768	hsa-miR-1306	CLIP-seq
MIRT910769	hsa-miR-1587	CLIP-seq
MIRT910770	hsa-miR-15a	CLIP-seq
MIRT910771	hsa-miR-15b	CLIP-seq
MIRT910772	hsa-miR-16	CLIP-seq
MIRT910773	hsa-miR-184	CLIP-seq
MIRT910774	hsa-miR-195	CLIP-seq
MIRT910775	hsa-miR-3126-5p	CLIP-seq
MIRT910776	hsa-miR-3144-5p	CLIP-seq
MIRT738274	hsa-miR-3150a-3p	CLIP-seq
MIRT910777	hsa-miR-3151	CLIP-seq
MIRT738276	hsa-miR-3175	CLIP-seq
MIRT910778	hsa-miR-3177-3p	CLIP-seq
MIRT910779	hsa-miR-3180	CLIP-seq
MIRT910780	hsa-miR-3180-3p	CLIP-seq
MIRT910781	hsa-miR-3187-5p	CLIP-seq
MIRT910782	hsa-miR-3196	CLIP-seq
MIRT910783	hsa-miR-331-3p	CLIP-seq
MIRT910784	hsa-miR-3612	CLIP-seq
MIRT910785	hsa-miR-361-3p	CLIP-seq
MIRT910786	hsa-miR-377	CLIP-seq
MIRT910787	hsa-miR-3940-3p	CLIP-seq
MIRT910788	hsa-miR-412	CLIP-seq
MIRT910789	hsa-miR-424	CLIP-seq
MIRT910790	hsa-miR-4283	CLIP-seq
MIRT910747	hsa-miR-4284	CLIP-seq
MIRT910791	hsa-miR-4292	CLIP-seq
MIRT910792	hsa-miR-4308	CLIP-seq
MIRT910793	hsa-miR-4319	CLIP-seq
MIRT910794	hsa-miR-4324	CLIP-seq
MIRT910795	hsa-miR-4437	CLIP-seq
MIRT910796	hsa-miR-4443	CLIP-seq
MIRT910797	hsa-miR-4450	CLIP-seq
MIRT910798	hsa-miR-4459	CLIP-seq
MIRT910799	hsa-miR-4467	CLIP-seq
MIRT910800	hsa-miR-4474-3p	CLIP-seq
MIRT910801	hsa-miR-4489	CLIP-seq
MIRT738283	hsa-miR-4492	CLIP-seq
MIRT738282	hsa-miR-4498	CLIP-seq
MIRT738280	hsa-miR-4505	CLIP-seq
MIRT910802	hsa-miR-4521	CLIP-seq
MIRT910803	hsa-miR-4525	CLIP-seq
MIRT910804	hsa-miR-4532	CLIP-seq
MIRT910751	hsa-miR-4639-3p	CLIP-seq
MIRT910805	hsa-miR-4656	CLIP-seq
MIRT910806	hsa-miR-4665-5p	CLIP-seq
MIRT738277	hsa-miR-4667-5p	CLIP-seq
MIRT910807	hsa-miR-4675	CLIP-seq
MIRT910753	hsa-miR-4684-5p	CLIP-seq
MIRT910808	hsa-miR-4694-3p	CLIP-seq
MIRT738278	hsa-miR-4700-5p	CLIP-seq
MIRT738284	hsa-miR-4707-5p	CLIP-seq
MIRT910809	hsa-miR-4723-5p	CLIP-seq
MIRT910810	hsa-miR-4730	CLIP-seq
MIRT738279	hsa-miR-4731-5p	CLIP-seq
MIRT910811	hsa-miR-4741	CLIP-seq
MIRT910812	hsa-miR-4759	CLIP-seq
MIRT910813	hsa-miR-4802-5p	CLIP-seq
MIRT910814	hsa-miR-497	CLIP-seq
MIRT910815	hsa-miR-566	CLIP-seq
MIRT910816	hsa-miR-603	CLIP-seq
MIRT910817	hsa-miR-612	CLIP-seq
MIRT910818	hsa-miR-625	CLIP-seq
MIRT910819	hsa-miR-637	CLIP-seq
MIRT910820	hsa-miR-650	CLIP-seq
MIRT910821	hsa-miR-661	CLIP-seq
MIRT910759	hsa-miR-665	CLIP-seq
MIRT738281	hsa-miR-762	CLIP-seq
MIRT910822	hsa-miR-765	CLIP-seq
MIRT738275	hsa-miR-939	CLIP-seq
MIRT738274	hsa-miR-3150a-3p	CLIP-seq
MIRT738276	hsa-miR-3175	CLIP-seq
MIRT738283	hsa-miR-4492	CLIP-seq
MIRT738282	hsa-miR-4498	CLIP-seq
MIRT738280	hsa-miR-4505	CLIP-seq
MIRT738277	hsa-miR-4667-5p	CLIP-seq
MIRT738278	hsa-miR-4700-5p	CLIP-seq
MIRT738284	hsa-miR-4707-5p	CLIP-seq
MIRT738279	hsa-miR-4731-5p	CLIP-seq
MIRT738281	hsa-miR-762	CLIP-seq
MIRT738275	hsa-miR-939	CLIP-seq
MIRT1970025	hsa-miR-3064-5p	CLIP-seq
MIRT738280	hsa-miR-4505	CLIP-seq
MIRT1970026	hsa-miR-1908	CLIP-seq
MIRT1970027	hsa-miR-1972	CLIP-seq
MIRT1970028	hsa-miR-24	CLIP-seq
MIRT738274	hsa-miR-3150a-3p	CLIP-seq
MIRT910777	hsa-miR-3151	CLIP-seq
MIRT738276	hsa-miR-3175	CLIP-seq
MIRT910778	hsa-miR-3177-3p	CLIP-seq
MIRT910779	hsa-miR-3180	CLIP-seq
MIRT910780	hsa-miR-3180-3p	CLIP-seq
MIRT1970029	hsa-miR-3180-5p	CLIP-seq
MIRT1970030	hsa-miR-3191	CLIP-seq
MIRT910782	hsa-miR-3196	CLIP-seq
MIRT910786	hsa-miR-377	CLIP-seq
MIRT910788	hsa-miR-412	CLIP-seq
MIRT910790	hsa-miR-4283	CLIP-seq
MIRT910747	hsa-miR-4284	CLIP-seq
MIRT1970031	hsa-miR-4419a	CLIP-seq
MIRT910795	hsa-miR-4437	CLIP-seq
MIRT910799	hsa-miR-4467	CLIP-seq
MIRT1970032	hsa-miR-4488	CLIP-seq
MIRT910801	hsa-miR-4489	CLIP-seq
MIRT738283	hsa-miR-4492	CLIP-seq
MIRT738282	hsa-miR-4498	CLIP-seq
MIRT738280	hsa-miR-4505	CLIP-seq
MIRT1970033	hsa-miR-4508	CLIP-seq
MIRT1970034	hsa-miR-4510	CLIP-seq
MIRT910804	hsa-miR-4532	CLIP-seq
MIRT910751	hsa-miR-4639-3p	CLIP-seq
MIRT1970035	hsa-miR-4642	CLIP-seq
MIRT1970036	hsa-miR-4649-5p	CLIP-seq
MIRT1970037	hsa-miR-4650-5p	CLIP-seq
MIRT738277	hsa-miR-4667-5p	CLIP-seq
MIRT910753	hsa-miR-4684-5p	CLIP-seq
MIRT1970038	hsa-miR-4697-5p	CLIP-seq
MIRT738278	hsa-miR-4700-5p	CLIP-seq
MIRT738284	hsa-miR-4707-5p	CLIP-seq
MIRT738279	hsa-miR-4731-5p	CLIP-seq
MIRT1970039	hsa-miR-491-5p	CLIP-seq
MIRT1970040	hsa-miR-5095	CLIP-seq
MIRT1970041	hsa-miR-520a-5p	CLIP-seq
MIRT1970042	hsa-miR-525-5p	CLIP-seq
MIRT1970043	hsa-miR-600	CLIP-seq
MIRT910816	hsa-miR-603	CLIP-seq
MIRT910819	hsa-miR-637	CLIP-seq
MIRT1970044	hsa-miR-663	CLIP-seq
MIRT738281	hsa-miR-762	CLIP-seq
MIRT910760	hsa-miR-922	CLIP-seq
MIRT738275	hsa-miR-939	CLIP-seq
MIRT910764	hsa-miR-1275	CLIP-seq
MIRT910766	hsa-miR-1285	CLIP-seq
MIRT2205997	hsa-miR-132	CLIP-seq
MIRT2205998	hsa-miR-212	CLIP-seq
MIRT2205999	hsa-miR-2355-5p	CLIP-seq
MIRT2206000	hsa-miR-2682	CLIP-seq
MIRT2206001	hsa-miR-298	CLIP-seq
MIRT2206002	hsa-miR-3127-5p	CLIP-seq
MIRT2206003	hsa-miR-3163	CLIP-seq
MIRT910781	hsa-miR-3187-5p	CLIP-seq
MIRT2206004	hsa-miR-34a	CLIP-seq
MIRT2206005	hsa-miR-34c-5p	CLIP-seq
MIRT910785	hsa-miR-361-3p	CLIP-seq
MIRT2206006	hsa-miR-3714	CLIP-seq
MIRT910786	hsa-miR-377	CLIP-seq
MIRT2206007	hsa-miR-383	CLIP-seq
MIRT2206008	hsa-miR-3918	CLIP-seq
MIRT910788	hsa-miR-412	CLIP-seq
MIRT2206009	hsa-miR-4260	CLIP-seq
MIRT2206010	hsa-miR-4300	CLIP-seq
MIRT2206011	hsa-miR-4476	CLIP-seq
MIRT2206012	hsa-miR-4487	CLIP-seq
MIRT2206013	hsa-miR-449a	CLIP-seq
MIRT2206014	hsa-miR-449b	CLIP-seq
MIRT2206015	hsa-miR-449c	CLIP-seq
MIRT910803	hsa-miR-4525	CLIP-seq
MIRT1970035	hsa-miR-4642	CLIP-seq
MIRT1970037	hsa-miR-4650-5p	CLIP-seq
MIRT910806	hsa-miR-4665-5p	CLIP-seq
MIRT2206016	hsa-miR-4722-3p	CLIP-seq
MIRT910755	hsa-miR-4773	CLIP-seq
MIRT910756	hsa-miR-4786-5p	CLIP-seq
MIRT2206017	hsa-miR-558	CLIP-seq
MIRT910816	hsa-miR-603	CLIP-seq
MIRT910817	hsa-miR-612	CLIP-seq
MIRT910819	hsa-miR-637	CLIP-seq
MIRT910821	hsa-miR-661	CLIP-seq
MIRT910759	hsa-miR-665	CLIP-seq
MIRT2206018	hsa-miR-920	CLIP-seq
MIRT910760	hsa-miR-922	CLIP-seq
MIRT2386482	hsa-miR-1228	CLIP-seq
MIRT2386483	hsa-miR-4711-3p	CLIP-seq
MIRT910816	hsa-miR-603	CLIP-seq
MIRT738274	hsa-miR-3150a-3p	CLIP-seq
MIRT738276	hsa-miR-3175	CLIP-seq
MIRT738283	hsa-miR-4492	CLIP-seq
MIRT738282	hsa-miR-4498	CLIP-seq
MIRT738280	hsa-miR-4505	CLIP-seq
MIRT738277	hsa-miR-4667-5p	CLIP-seq
MIRT738278	hsa-miR-4700-5p	CLIP-seq
MIRT738284	hsa-miR-4707-5p	CLIP-seq
MIRT738279	hsa-miR-4731-5p	CLIP-seq
MIRT738281	hsa-miR-762	CLIP-seq
MIRT738275	hsa-miR-939	CLIP-seq
MIRT738274	hsa-miR-3150a-3p	CLIP-seq
MIRT738276	hsa-miR-3175	CLIP-seq
MIRT738283	hsa-miR-4492	CLIP-seq
MIRT738282	hsa-miR-4498	CLIP-seq
MIRT738280	hsa-miR-4505	CLIP-seq
MIRT738277	hsa-miR-4667-5p	CLIP-seq
MIRT738278	hsa-miR-4700-5p	CLIP-seq
MIRT738284	hsa-miR-4707-5p	CLIP-seq
MIRT738279	hsa-miR-4731-5p	CLIP-seq
MIRT738281	hsa-miR-762	CLIP-seq
MIRT738275	hsa-miR-939	CLIP-seq
MIRT2206003	hsa-miR-3163	CLIP-seq

Transcription factors

Show/Hide all(1)

Transcription factor	Regulation	Reference
CREB1	Unknown	17334997

Show/Hide all(26)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003713	Function	Transcription coactivator activity	IBA
GO:0005515	Function	Protein binding	IPI	14506290, 20936779, 32296183, 35271311, 36931259
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	14506290
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005886	Component	Plasma membrane	IDA
GO:0007613	Process	Memory	IEA
GO:0008140	Function	CAMP response element binding protein binding	IBA
GO:0008140	Function	CAMP response element binding protein binding	IDA	14536081
GO:0008140	Function	CAMP response element binding protein binding	IEA
GO:0016604	Component	Nuclear body	IDA
GO:0032793	Process	Positive regulation of CREB transcription factor activity	ISS
GO:0043153	Process	Entrainment of circadian clock by photoperiod	IEA
GO:0043153	Process	Entrainment of circadian clock by photoperiod	ISS
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IBA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	14536081
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IEA
GO:0048511	Process	Rhythmic process	IEA
GO:0051289	Process	Protein homotetramerization	IEA
GO:0071320	Process	Cellular response to cAMP	IBA
GO:0097009	Process	Energy homeostasis	IEA
GO:1902631	Process	Negative regulation of membrane hyperpolarization	IEA

MIM	HGNC	e!Ensembl
607536	16062	ENSG00000105662

Protein

UniProt ID

Q6UUV9

Protein name

CREB-regulated transcription coactivator 1 (Mucoepidermoid carcinoma translocated protein 1) (Transducer of regulated cAMP response element-binding protein 1) (TORC-1) (Transducer of CREB protein 1)

Protein function

Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts indep

PDB

7D8H , 7D8P , 7D9V

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF12884	TORC_N	6 → 66	Transducer of regulated CREB activity, N terminus	Family
PF12885	TORC_M	148 → 293	Transducer of regulated CREB activity middle domain	Family
PF12886	TORC_C	559 → 634	Transducer of regulated CREB activity, C terminus	Family

Tissue specificity

TISSUE SPECIFICITY: Highly expressed in adult and fetal brain. Located to specific regions such as the prefrontal cortex and cerebellum. Very low expression in other tissues such as heart, spleen, lung, skeletal muscle, salivary gland, ovary and kidney. {

Sequence

MATSNNPRKFSEKIALHNQKQAEETAAFEEVMKDLSLTRAARLQLQKSQYLQLGPSRGQY
YGGSLPNVNQIGSGTMDLPFQTPFQSSGLDTSRTTRHHGLVDRVYRERGRLGSPHRRPLS
VDKHGRQADSCPYGTMYLSPPADTSWRRTNSDSALHQSTMTPTQPESFSSGSQDVHQKRV
LLLTVPGMEETTSEADKNLSKQAWDTKKTGSRPKSCEVPGINIFPSADQENTTALIPATH
NTGGSLPDLTNIHFPSPLPTPLDPEEPTFPALSSSSSTGNLAANLTHLGIGGAGQGMSTP
GSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFTQAGS
QQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVTVPSS
LPQSPPENPGQPSMGIDIASAPALQQYRTSAGSPANQSPTSPVSNQGFSPGSSPQHTSTL
GSVFGDAYYEQQMAARQANALSHQLEQFNMMENAISSSSLYSPGSTLNYSQAAMMGLTGS
HGSLPDSQQLGYASHSGIPNIILTVTGESPPSLSKELTSSLAGVGDVSFDSDSQFPLDEL
KIDPLTLDGLHMLNDPDMVLADPATEDTFRMDRL

Sequence length

634

Interactions

View interactions

	KEGG		Reactome
	Human T-cell leukemia virus 1 infection		Transcriptional activation of mitochondrial biogenesis Circadian Clock

Show/Hide Unknown Diseases (6)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Alzheimer disease	Alzheimer's disease or family history of Alzheimer's disease	N/A	N/A	GWAS
Barrett esophagus	Barrett's esophagus	N/A	N/A	GWAS
Diabetes	Type 2 diabetes	N/A	N/A	GWAS
Gastroesophageal Reflux Disease	Gastroesophageal reflux disease	N/A	N/A	GWAS
Heart Failure	Heart failure	N/A	N/A	GWAS
Metabolic Syndrome	Metabolic syndrome	N/A	N/A	GWAS

Show/Hide Text Mining Associations (35)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Acrospiroma	Associate	29079171, 37505808
Adenocarcinoma	Associate	24121790, 25447851, 34505128, 35766871
Alzheimer Disease	Associate	27094739
Anxiety	Associate	29225348
Astrocytoma	Associate	22805177
Barrett Esophagus	Associate	25447851, 34505128, 35766871
Brain Diseases	Associate	22805177
Breast Neoplasms	Associate	30380176, 31978326
Carcinoma Hepatocellular	Associate	25300488
Carcinoma Mucoepidermoid	Associate	15269296, 19164581, 19749740, 20625861, 23018873, 23035786, 24893972, 26503699, 27340278, 28438292, 31351495, 32221865, 36366450, 39332274, 39888274
Central Nervous System Vascular Malformations	Associate	22805177
Chronobiology Disorders	Associate	31153815
Depressive Disorder Major	Associate	27002284
Diabetes Mellitus	Associate	31153815
Glioma Subependymal	Associate	22805177
Inflammation	Associate	22805177
Kidney Neoplasms	Associate	22685542
Lung Neoplasms	Associate	20010869, 25465874
Mental Disorders	Associate	23925723, 31878957
Mucoepidermoid Tumor	Associate	19827123
Multiple Myeloma	Associate	22556409
Neoplasm Invasiveness	Stimulate	35920319
Neoplasms	Associate	23018873, 26676751, 28539123, 29079171, 29533464, 34011559, 35751643, 38184586
Neoplasms Adipose Tissue	Associate	23925723
Nerve Degeneration	Associate	37541638
Obesity	Associate	23925723, 27002284, 31153815, 31878957, 34588385
Salivary Gland Diseases	Associate	33832503
Salivary Gland Neoplasms	Associate	15961999, 19827123, 20010869, 30380176
Sarcoma	Associate	29533464
Sarcoma Small Cell	Associate	29533464
Squamous Intraepithelial Lesions	Associate	35920319
Thoracic Neoplasms	Stimulate	20010869
Triple Negative Breast Neoplasms	Associate	26676751
Tuberous Sclerosis	Associate	22805177
Weight Gain	Associate	23925723, 31878957

CRTC1 (CREB regulated transcription coactivator 1)