Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	23349
Gene name	PHD finger protein 24
Gene symbol	PHF24
Synonyms (NCBI Gene)	GINIP
Chromosome	9
Chromosome location	9p13.3

Show/Hide all (27)

miRTarBase ID	miRNA	Experiments	Reference
MIRT741710	hsa-miR-6777-3p	HITS-CLIP	23824327
MIRT741711	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT741712	hsa-miR-4287	HITS-CLIP	23824327
MIRT741713	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT741714	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT741715	hsa-miR-5002-3p	HITS-CLIP	23824327
MIRT741716	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT741717	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT741718	hsa-miR-5585-3p	HITS-CLIP	23824327
MIRT741719	hsa-miR-7703	HITS-CLIP	23824327
MIRT741720	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT741710	hsa-miR-6777-3p	HITS-CLIP	23824327
MIRT741711	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT741712	hsa-miR-4287	HITS-CLIP	23824327
MIRT741713	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT741714	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT741715	hsa-miR-5002-3p	HITS-CLIP	23824327
MIRT741716	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT741717	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT741718	hsa-miR-5585-3p	HITS-CLIP	23824327
MIRT741719	hsa-miR-7703	HITS-CLIP	23824327
MIRT741720	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT754814	hsa-miR-1273d	PAR-CLIP	23708386
MIRT754815	hsa-miR-1288-5p	PAR-CLIP	23708386
MIRT754816	hsa-miR-1972	PAR-CLIP	23708386
MIRT754817	hsa-miR-5189-3p	PAR-CLIP	23708386
MIRT754818	hsa-miR-513a-5p	PAR-CLIP	23708386

Show/Hide all (13)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003714	Function	Transcription corepressor activity	IBA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IBA
GO:0005737	Component	Cytoplasm	IBA
GO:0007214	Process	Gamma-aminobutyric acid signaling pathway	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0008277	Process	Regulation of G protein-coupled receptor signaling pathway	IEA
GO:0030672	Component	Synaptic vesicle membrane	IEA
GO:0032228	Process	Regulation of synaptic transmission, GABAergic	IEA
GO:0045892	Process	Negative regulation of DNA-templated transcription	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0050966	Process	Detection of mechanical stimulus involved in sensory perception of pain	IEA
GO:0098978	Component	Glutamatergic synapse	IEA

MIM	HGNC	e!Ensembl
619928	29180	ENSG00000122733

Q9UPV7

Protein name

PHD finger protein 24

PDB

1WIL , 5XHT

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF16744	Zf_RING	126 → 198	KIAA1045 RING finger	Domain

Sequence

MGVLMSKRQTVEQVQKVSLAVSAFKDGLRDRPSIRRTGELPGSRRGTVEGSVQEVQEEKE
AEAGTSVVQEESSAGRAAWERLRDGRGVEPEEFDRTSRFTPPAFIRPTRKLDDDKPPEIC
LEPREPVVNDEMCDVCEVWTAESLFPCRVCTRVFHDGCLRRMGYIQGDSAAEVTEMAHTE
TGWSCHYCDNINLLLTEEEMYSLTETFQRCKVIPDCSLTLEDFLRYRHQAAKRGDRDRAL
SEEQEEQAARQFAALDPEHRGHIEWPDFLSHESLLLLQQLRPQNSLLRLLTVKERERARA
AFLARGSGSTVSEAECRRAQHSWFCKRFPEAPSCSVSISHVGPIADSSPASSSSKSQDKT
LLPTEQESRFVDWPTFLQENVLYILAARPNSAAIHLKPPG

Sequence length

400

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (3)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Breast ductal adenocarcinoma	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MALIGNANT EPITHELIAL TUMOR OF OVARY	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OVARIAN CARCINOMA	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

PHF24 (PHD finger protein 24)