SLC9A8 (solute carrier family 9 member A8)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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23315 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Solute carrier family 9 member A8 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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SLC9A8 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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NHE-8, NHE8 |
Chromosome
Chromosome number
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20 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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20q13.13 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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Sodium-hydrogen exchangers (NHEs), such as SLC9A8, are integral transmembrane proteins that exchange extracellular Na+ for intracellular H+. NHEs have multiple functions, including intracellular pH homeostasis, cell volume regulation, and electroneutral N |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q9Y2E8 | ||||||||||
Protein name | Sodium/hydrogen exchanger 8 (Na(+)/H(+) exchanger 8) (NHE-8) (Solute carrier family 9 member 8) | ||||||||||
Protein function | Na(+)/H(+) antiporter. Mediates the electoneutral exchange of intracellular H(+) ions for extracellular Na(+) in 1:1 stoichiometry (PubMed:15522866). Acts as an Na(+)/H(+) exchanger in the trans-Golgi. Contributes to the regulation of pH regulat | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Ubiquitous. Strongly expressed in skeletal muscle and kidney (PubMed:15522866). Detected throughout the entire gastrointestinal tract, with high expression detected in stomach, duodenum and ascending colon (PubMed:18209477). {ECO:00002 | ||||||||||
Sequence |
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Sequence length | 581 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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