Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	23306
Gene name Gene Name - the full gene name approved by the HGNC.	Nuclear envelope integral membrane protein 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	NEMP1
Synonyms (NCBI Gene) Gene synonyms aliases	TMEM194, TMEM194A
Chromosome Chromosome number	12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	12q13.3

Show/Hide all(70)

miRTarBase ID	miRNA	Experiments	Reference
MIRT439433	hsa-miR-155-5p	HITS-CLIP	22473208
MIRT439433	hsa-miR-155-5p	HITS-CLIP	22473208
MIRT726297	hsa-miR-92a-3p	HITS-CLIP	22473208
MIRT726296	hsa-miR-92b-3p	HITS-CLIP	22473208
MIRT726295	hsa-miR-32-5p	HITS-CLIP	22473208
MIRT741089	hsa-miR-196a-5p	HITS-CLIP	23313552
MIRT741090	hsa-miR-196b-5p	HITS-CLIP	23313552
MIRT741091	hsa-miR-4500	HITS-CLIP	23313552
MIRT741092	hsa-let-7d-5p	HITS-CLIP	23313552
MIRT741093	hsa-miR-98-5p	HITS-CLIP	23313552
MIRT741094	hsa-let-7e-5p	HITS-CLIP	23313552
MIRT741095	hsa-miR-4458	HITS-CLIP	23313552
MIRT741096	hsa-let-7a-5p	HITS-CLIP	23313552
MIRT741097	hsa-let-7i-5p	HITS-CLIP	23313552
MIRT741098	hsa-let-7g-5p	HITS-CLIP	23313552
MIRT741099	hsa-let-7b-5p	HITS-CLIP	23313552
MIRT741100	hsa-let-7c-5p	HITS-CLIP	23313552
MIRT741101	hsa-let-7f-5p	HITS-CLIP	23313552
MIRT741102	hsa-miR-141-3p	HITS-CLIP	23313552
MIRT741103	hsa-miR-200a-3p	HITS-CLIP	23313552
MIRT741104	hsa-miR-6757-3p	HITS-CLIP	23313552
MIRT741105	hsa-miR-1197	HITS-CLIP	23313552
MIRT741106	hsa-miR-4722-3p	HITS-CLIP	23313552
MIRT741107	hsa-miR-6727-3p	HITS-CLIP	23313552
MIRT741108	hsa-miR-6747-3p	HITS-CLIP	23313552
MIRT741109	hsa-miR-130b-5p	HITS-CLIP	23313552
MIRT741110	hsa-miR-7162-3p	HITS-CLIP	23313552
MIRT741111	hsa-miR-875-3p	HITS-CLIP	23313552
MIRT741112	hsa-miR-6128	HITS-CLIP	23313552
MIRT741113	hsa-miR-4456	HITS-CLIP	23313552
MIRT741114	hsa-miR-3124-3p	HITS-CLIP	23313552
MIRT741115	hsa-miR-570-3p	HITS-CLIP	23313552
MIRT741116	hsa-miR-202-3p	HITS-CLIP	23313552
MIRT741117	hsa-miR-5189-3p	HITS-CLIP	23313552
MIRT741118	hsa-miR-760	HITS-CLIP	23313552
MIRT741119	hsa-miR-8071	HITS-CLIP	23313552
MIRT741120	hsa-miR-6880-5p	HITS-CLIP	23313552
MIRT741121	hsa-miR-3165	HITS-CLIP	23313552
MIRT741122	hsa-miR-4703-3p	HITS-CLIP	23313552
MIRT741123	hsa-miR-668-3p	HITS-CLIP	23313552
MIRT741124	hsa-miR-6755-3p	HITS-CLIP	23313552
MIRT741125	hsa-miR-124-3p	HITS-CLIP	23313552
MIRT741126	hsa-miR-506-3p	HITS-CLIP	23313552
MIRT741127	hsa-miR-3117-3p	HITS-CLIP	23313552
MIRT741128	hsa-miR-4477b	HITS-CLIP	23313552
MIRT741129	hsa-miR-3074-5p	HITS-CLIP	23313552
MIRT741130	hsa-miR-7152-5p	HITS-CLIP	23313552
MIRT741131	hsa-miR-7856-5p	HITS-CLIP	23313552
MIRT741706	hsa-miR-5700	HITS-CLIP	23824327
MIRT741707	hsa-miR-586	HITS-CLIP	23824327
MIRT741708	hsa-miR-1246	HITS-CLIP	23824327
MIRT741709	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT741706	hsa-miR-5700	HITS-CLIP	23824327
MIRT741707	hsa-miR-586	HITS-CLIP	23824327
MIRT741708	hsa-miR-1246	HITS-CLIP	23824327
MIRT741709	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT741706	hsa-miR-5700	HITS-CLIP	23824327
MIRT741707	hsa-miR-586	HITS-CLIP	23824327
MIRT741708	hsa-miR-1246	HITS-CLIP	23824327
MIRT741709	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT754451	hsa-miR-302c-3p	PAR-CLIP	22012620
MIRT754452	hsa-miR-520f-3p	PAR-CLIP	22012620
MIRT754453	hsa-miR-128-3p	PAR-CLIP	22012620
MIRT754454	hsa-miR-216a-3p	PAR-CLIP	22012620
MIRT754455	hsa-miR-3681-3p	PAR-CLIP	22012620
MIRT754456	hsa-miR-3160-5p	PAR-CLIP	22012620
MIRT754457	hsa-miR-513b-5p	PAR-CLIP	22012620
MIRT754458	hsa-miR-513a-5p	PAR-CLIP	22012620
MIRT754459	hsa-miR-27a-3p	PAR-CLIP	22012620
MIRT754460	hsa-miR-27b-3p	PAR-CLIP	22012620

Show/Hide all(6)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003674	Function	Molecular_function	ND
GO:0005635	Component	Nuclear envelope	IBA	21873635
GO:0005635	Component	Nuclear envelope	ISS
GO:0005637	Component	Nuclear inner membrane	IEA
GO:0016021	Component	Integral component of membrane	IEA
GO:0071763	Process	Nuclear membrane organization	IMP	32923640

MIM	HGNC	e!Ensembl
616496	29001	ENSG00000166881

Protein

UniProt ID

O14524

Protein name

Nuclear envelope integral membrane protein 1

Protein function

Together with EMD, contributes to nuclear envelope stiffness in germ cells (PubMed:32923640). Required for female fertility (By similarity). Essential for normal erythropoiesis (By similarity). Required for efficient nuclear envelope opening and

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF10225	NEMP	152 → 398	NEMP family	Family

Sequence

MAGGMKVAVSPAVGPGPWGSGVGGGGTVRLLLILSGCLVYGTAETDVNVVMLQESQVCEK
RASQQFCYTNVLIPKWHDIWTRIQIRVNSSRLVRVTQVENEEKLKELEQFSIWNFFSSFL
KEKLNDTYVNVGLYSTKTCLKVEIIEKDTKYSVIVIRRFDPKLFLVFLLGLMLFFCGDLL
SRSQIFYYSTGMTVGIVASLLIIIFILSKFMPKKSPIYVILVGGWSFSLYLIQLVFKNLQ
EIWRCYWQYLLSYVLTVGFMSFAVCYKYGPLENERSINLLTWTLQLMGLCFMYSGIQIPH
IALAIIIIALCTKNLEHPIQWLYITCRKVCKGAEKPVPPRLLTEEEYRIQGEVETRKALE
ELREFCNSPDCSAWKTVSRIQSPKRFADFVEGSSHLTPNEVSVHEQEYGLGSIIAQDEIY
EEASSEEEDSYSRCPAITQNNFLT

Sequence length

444

Interactions

View interactions

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Leukemia	Leukemia, Myelocytic, Acute	rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297	27903959

Show/Hide Unknown Diseases (2)

Disease term	Disease name	Source
Unknown
Asthma	Asthma	GWAS
Insomnia	Insomnia	GWAS

Show/Hide Text Mining Associations (1)

Disease Name	Relationship Type	References
Associations from Text Mining
Breast Neoplasms	Associate	31854049

NEMP1 (nuclear envelope integral membrane protein 1)