Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein
Entrez ID	23306
Gene name	Nuclear envelope integral membrane protein 1
Gene symbol	NEMP1
Synonyms (NCBI Gene)	TMEM194TMEM194A
Chromosome	12
Chromosome location	12q13.3

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miRTarBase ID	miRNA	Experiments	Reference
MIRT439433	hsa-miR-155-5p	HITS-CLIP	22473208
MIRT439433	hsa-miR-155-5p	HITS-CLIP	22473208
MIRT726297	hsa-miR-92a-3p	HITS-CLIP	22473208
MIRT726296	hsa-miR-92b-3p	HITS-CLIP	22473208
MIRT726295	hsa-miR-32-5p	HITS-CLIP	22473208
MIRT741089	hsa-miR-196a-5p	HITS-CLIP	23313552
MIRT741090	hsa-miR-196b-5p	HITS-CLIP	23313552
MIRT741091	hsa-miR-4500	HITS-CLIP	23313552
MIRT741092	hsa-let-7d-5p	HITS-CLIP	23313552
MIRT741093	hsa-miR-98-5p	HITS-CLIP	23313552
MIRT741094	hsa-let-7e-5p	HITS-CLIP	23313552
MIRT741095	hsa-miR-4458	HITS-CLIP	23313552
MIRT741096	hsa-let-7a-5p	HITS-CLIP	23313552
MIRT741097	hsa-let-7i-5p	HITS-CLIP	23313552
MIRT741098	hsa-let-7g-5p	HITS-CLIP	23313552
MIRT741099	hsa-let-7b-5p	HITS-CLIP	23313552
MIRT741100	hsa-let-7c-5p	HITS-CLIP	23313552
MIRT741101	hsa-let-7f-5p	HITS-CLIP	23313552
MIRT741102	hsa-miR-141-3p	HITS-CLIP	23313552
MIRT741103	hsa-miR-200a-3p	HITS-CLIP	23313552
MIRT741104	hsa-miR-6757-3p	HITS-CLIP	23313552
MIRT741105	hsa-miR-1197	HITS-CLIP	23313552
MIRT741106	hsa-miR-4722-3p	HITS-CLIP	23313552
MIRT741107	hsa-miR-6727-3p	HITS-CLIP	23313552
MIRT741108	hsa-miR-6747-3p	HITS-CLIP	23313552
MIRT741109	hsa-miR-130b-5p	HITS-CLIP	23313552
MIRT741110	hsa-miR-7162-3p	HITS-CLIP	23313552
MIRT741111	hsa-miR-875-3p	HITS-CLIP	23313552
MIRT741112	hsa-miR-6128	HITS-CLIP	23313552
MIRT741113	hsa-miR-4456	HITS-CLIP	23313552
MIRT741114	hsa-miR-3124-3p	HITS-CLIP	23313552
MIRT741115	hsa-miR-570-3p	HITS-CLIP	23313552
MIRT741116	hsa-miR-202-3p	HITS-CLIP	23313552
MIRT741117	hsa-miR-5189-3p	HITS-CLIP	23313552
MIRT741118	hsa-miR-760	HITS-CLIP	23313552
MIRT741119	hsa-miR-8071	HITS-CLIP	23313552
MIRT741120	hsa-miR-6880-5p	HITS-CLIP	23313552
MIRT741121	hsa-miR-3165	HITS-CLIP	23313552
MIRT741122	hsa-miR-4703-3p	HITS-CLIP	23313552
MIRT741123	hsa-miR-668-3p	HITS-CLIP	23313552
MIRT741124	hsa-miR-6755-3p	HITS-CLIP	23313552
MIRT741125	hsa-miR-124-3p	HITS-CLIP	23313552
MIRT741126	hsa-miR-506-3p	HITS-CLIP	23313552
MIRT741127	hsa-miR-3117-3p	HITS-CLIP	23313552
MIRT741128	hsa-miR-4477b	HITS-CLIP	23313552
MIRT741129	hsa-miR-3074-5p	HITS-CLIP	23313552
MIRT741130	hsa-miR-7152-5p	HITS-CLIP	23313552
MIRT741131	hsa-miR-7856-5p	HITS-CLIP	23313552
MIRT741706	hsa-miR-5700	HITS-CLIP	23824327
MIRT741707	hsa-miR-586	HITS-CLIP	23824327
MIRT741708	hsa-miR-1246	HITS-CLIP	23824327
MIRT741709	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT741706	hsa-miR-5700	HITS-CLIP	23824327
MIRT741707	hsa-miR-586	HITS-CLIP	23824327
MIRT741708	hsa-miR-1246	HITS-CLIP	23824327
MIRT741709	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT741706	hsa-miR-5700	HITS-CLIP	23824327
MIRT741707	hsa-miR-586	HITS-CLIP	23824327
MIRT741708	hsa-miR-1246	HITS-CLIP	23824327
MIRT741709	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT754451	hsa-miR-302c-3p	PAR-CLIP	22012620
MIRT754452	hsa-miR-520f-3p	PAR-CLIP	22012620
MIRT754453	hsa-miR-128-3p	PAR-CLIP	22012620
MIRT754454	hsa-miR-216a-3p	PAR-CLIP	22012620
MIRT754455	hsa-miR-3681-3p	PAR-CLIP	22012620
MIRT754456	hsa-miR-3160-5p	PAR-CLIP	22012620
MIRT754457	hsa-miR-513b-5p	PAR-CLIP	22012620
MIRT754458	hsa-miR-513a-5p	PAR-CLIP	22012620
MIRT754459	hsa-miR-27a-3p	PAR-CLIP	22012620
MIRT754460	hsa-miR-27b-3p	PAR-CLIP	22012620

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IEA
GO:0005635	Component	Nuclear envelope	IBA
GO:0005635	Component	Nuclear envelope	IEA
GO:0005635	Component	Nuclear envelope	ISS
GO:0005637	Component	Nuclear inner membrane	IEA
GO:0016020	Component	Membrane	IEA
GO:0043131	Process	Erythrocyte enucleation	IEA
GO:0043131	Process	Erythrocyte enucleation	ISS
GO:0043249	Process	Erythrocyte maturation	IEA
GO:0043249	Process	Erythrocyte maturation	ISS
GO:0071763	Process	Nuclear membrane organization	IMP	32923640

MIM	HGNC	e!Ensembl
616496	29001	ENSG00000166881

O14524

Protein name

Nuclear envelope integral membrane protein 1

Protein function

Together with EMD, contributes to nuclear envelope stiffness in germ cells (PubMed:32923640). Required for female fertility (By similarity). Essential for normal erythropoiesis (By similarity). Required for efficient nuclear envelope opening and

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF10225	NEMP	152 → 398	NEMP family	Family

Sequence

MAGGMKVAVSPAVGPGPWGSGVGGGGTVRLLLILSGCLVYGTAETDVNVVMLQESQVCEK
RASQQFCYTNVLIPKWHDIWTRIQIRVNSSRLVRVTQVENEEKLKELEQFSIWNFFSSFL
KEKLNDTYVNVGLYSTKTCLKVEIIEKDTKYSVIVIRRFDPKLFLVFLLGLMLFFCGDLL
SRSQIFYYSTGMTVGIVASLLIIIFILSKFMPKKSPIYVILVGGWSFSLYLIQLVFKNLQ
EIWRCYWQYLLSYVLTVGFMSFAVCYKYGPLENERSINLLTWTLQLMGLCFMYSGIQIPH
IALAIIIIALCTKNLEHPIQWLYITCRKVCKGAEKPVPPRLLTEEEYRIQGEVETRKALE
ELREFCNSPDCSAWKTVSRIQSPKRFADFVEGSSHLTPNEVSVHEQEYGLGSIIAQDEIY
EEASSEEEDSYSRCPAITQNNFLT

Sequence length

444

Interactions

View interactions

NEMP1 (nuclear envelope integral membrane protein 1)