ASTN2 (astrotactin 2)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 23245 |
| Gene name | Astrotactin 2 |
| Gene symbol | ASTN2 |
| Synonyms (NCBI Gene) |
bA67K19.1
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| Chromosome | 9 |
| Chromosome location | 9q33.1 |
| Summary | This gene encodes a protein that is expressed in the brain and may function in neuronal migration, based on functional studies of the related astrotactin 1 gene in human and mouse. A deletion at this locus has been associated with schizophrenia. Multiple |
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miRNA
miRNA information provided by mirtarbase database.
803
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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O75129 | |||||||||||||||||||||||||
| Protein name | Astrotactin-2 | |||||||||||||||||||||||||
| Protein function | Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1 (By similarity). Selectively binds in | |||||||||||||||||||||||||
| PDB | 5J67 , 5J68 , 5J69 | |||||||||||||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 1339 | |||||||||||||||||||||||||
| Interactions | View interactions | |||||||||||||||||||||||||
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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