PACS2 (phosphofurin acidic cluster sorting protein 2)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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23241 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Phosphofurin acidic cluster sorting protein 2 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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PACS2 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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DEE66, EIEE66, PACS-2, PACS1L |
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Chromosome
Chromosome number
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14 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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14q32.33 |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | Q86VP3 | ||||||||||
| Protein name | Phosphofurin acidic cluster sorting protein 2 (PACS-2) (PACS1-like protein) | ||||||||||
| Protein function | Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptotic inducer, translocates BIB to | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Broadly expressed, with greatest levels in skeletal muscle followed by heart, brain, pancreas and testis. {ECO:0000269|PubMed:15692567}. | ||||||||||
| Sequence |
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| Sequence length | 889 | ||||||||||
| Interactions | View interactions | ||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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