Gene Gene information from NCBI Gene database.
Entrez ID 23231
Gene name SEL1L family member 3
Gene symbol SEL1L3
Synonyms (NCBI Gene)
Sel-1L3
Chromosome 4
Chromosome location 4p15.2
miRNA miRNA information provided by mirtarbase database.
526
miRTarBase ID miRNA Experiments Reference
MIRT018962 hsa-miR-335-5p Microarray 18185580
MIRT020326 hsa-miR-130b-3p Sequencing 20371350
MIRT031265 hsa-miR-19b-3p Sequencing 20371350
MIRT052626 hsa-let-7a-5p CLASH 23622248
MIRT038723 hsa-miR-93-3p CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
1
GO ID Ontology Definition Evidence Reference
GO:0016020 Component Membrane IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
619914 29108 ENSG00000091490
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q68CR1
Protein name Protein sel-1 homolog 3 (Suppressor of lin-12-like protein 3) (Sel-1L3)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF08238 Sel1 570 596 Sel1 repeat Repeat
PF08238 Sel1 689 723 Sel1 repeat Repeat
PF08238 Sel1 728 762 Sel1 repeat Repeat
PF08238 Sel1 796 834 Sel1 repeat Repeat
PF08238 Sel1 947 983 Sel1 repeat Repeat
Sequence
MQRRGAGLGWPRQQQQQPPPLAVGPRAAAMVPSGGVPQGLGGRSACALLLLCYLNVVPSL
GRQTSLTTSVIPKAEQSVAYKDFIYFTVFEGNVRNVSEVSVEYLCSQPCVVNLEAVVSSE
FRSSIPVYKKRWKNEKHLHTSRTQIVHVKFPSIMVYRDDYFIRHSISVSAVIVRAWITHK
YSGRDWNVKWEENLLHAVAKNYTLLQTIPPFERPFKDHQVCLEWNMGYIWNLRANRIPQC
PLENDVVALLGFPYASSGENTGIVKKFPRFRNRELEATRRQRMDYPVFTVSLWLYLLHYC
KANLCGILYFVDSNEMYGTPSVFLTEEGYLHIQMHLVKGEDLAVKTKFIIPLKEWFRLDI
SFNGGQIVVTTSIGQDLKSYHNQTISFREDFHYNDTAGYFIIGGSRYVAGIEGFFGPLKY
YRLRSLHPAQIFNPLLEKQLAEQIKLYYERCAEVQEIVSVYASAAKHGGERQEACHLHNS
YLDLQRRYGRPSMCRAFPWEKELKDKHPSLFQALLEMDLLTVPRNQNESVSEIGGKIFEK
AVKRLSSIDGLHQISSIVPFLTDSSCCGYHKASYYLAVFYETGLNVPRDQLQGMLYSLVG
GQGSERLSSMNLGYKHYQGIDNYPLDWELSYAYYSNIATKTPLDQHTLQGDQAYVETIRL
KDDEILKVQTKEDGDVFMWLKHEATRGNAAAQQRLAQMLFWGQQGVAKNPEAAIEWYAKG
ALE
TEDPALIYDYAIVLFKGQGVKKNRRLALELMKKAASKGLHQAVNGLGWYYHKFKKNY
AKAAKYWLKAEEMGNPDASYNLGVLHLDGIFPGVPGRNQTLAGEYFHKAAQGGHMEGTLW
CSLYYITGNLETFPRDPEKAVVWAKHVAEKNGYLGHVIRKGLNAYLEGSWHEALLYYVLA
AETGIEVSQTNLAHICEERPDLARRYLGVNCVWRYYNFSVFQIDAPSFAYLKMGDLYYYG
HQNQSQDLELSVQMYAQAALDGD
SQGFFNLALLIEEGTIIPHHILDFLEIDSTLHSNNIS
ILQELYERCWSHSNEESFSPCSLAWLYLHLRLLWGAILHSALIYFLGTFLLSILIAWTVQ
YFQSVSASDPPPRPSQASPDTATSTASPAVTPAADASDQDQPTVTNNPEPRG
Sequence length 1132
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
8
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
Acute myeloid leukemia Likely benign ClinVar
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Cervical cancer Likely benign ClinVar
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
CIRRHOSIS OF LIVER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Colon adenocarcinoma Uncertain significance ClinVar
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References Evidence Score
Atherosclerosis Associate 37993256
★☆☆☆☆
Found in Text Mining only
Carcinoma Renal Cell Associate 37993256
★☆☆☆☆
Found in Text Mining only
Hypertension Associate 28234671
★☆☆☆☆
Found in Text Mining only
Inflammation Associate 37993256
★☆☆☆☆
Found in Text Mining only
Melanoma Associate 33753855
★☆☆☆☆
Found in Text Mining only
Thyroid Neoplasms Associate 36930113
★☆☆☆☆
Found in Text Mining only
Triple Negative Breast Neoplasms Associate 38111587
★☆☆☆☆
Found in Text Mining only