DTX4 (deltex E3 ubiquitin ligase 4)

Gene

• Entrez ID: 23220
• Gene name: Deltex E3 ubiquitin ligase 4
• Gene symbol: DTX4
• Synonyms (NCBI Gene): RNF155
• Chromosome: 11
• Chromosome location: 11q12.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT027766	hsa-miR-98-5p	Microarray	19088304
MIRT715184	hsa-miR-130a-3p	HITS-CLIP	19536157
MIRT715183	hsa-miR-130b-3p	HITS-CLIP	19536157
MIRT715182	hsa-miR-301a-3p	HITS-CLIP	19536157
MIRT715181	hsa-miR-301b-3p	HITS-CLIP	19536157
MIRT715180	hsa-miR-3666	HITS-CLIP	19536157
MIRT715179	hsa-miR-4295	HITS-CLIP	19536157
MIRT715178	hsa-miR-454-3p	HITS-CLIP	19536157
MIRT715177	hsa-miR-4709-5p	HITS-CLIP	19536157
MIRT715176	hsa-miR-5003-5p	HITS-CLIP	19536157
MIRT715175	hsa-miR-148a-3p	HITS-CLIP	19536157
MIRT715174	hsa-miR-148b-3p	HITS-CLIP	19536157
MIRT715173	hsa-miR-152-3p	HITS-CLIP	19536157
MIRT512011	hsa-miR-448	HITS-CLIP	21572407
MIRT512006	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT512010	hsa-miR-598-3p	HITS-CLIP	21572407
MIRT512009	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT512008	hsa-miR-586	HITS-CLIP	21572407
MIRT523996	hsa-miR-6715a-3p	HITS-CLIP	21572407
MIRT512007	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT523995	hsa-miR-6715b-3p	HITS-CLIP	21572407
MIRT512010	hsa-miR-598-3p	HITS-CLIP	21572407
MIRT512009	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT512007	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT512006	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT512011	hsa-miR-448	HITS-CLIP	23313552
MIRT512006	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT512009	hsa-miR-5011-5p	HITS-CLIP	23313552
MIRT512008	hsa-miR-586	HITS-CLIP	23313552
MIRT512007	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT512011	hsa-miR-448	HITS-CLIP	23824327
MIRT512010	hsa-miR-598-3p	HITS-CLIP	23824327
MIRT512009	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT512007	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT512006	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT512011	hsa-miR-448	PAR-CLIP	20371350
MIRT512006	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT512010	hsa-miR-598-3p	PAR-CLIP	20371350
MIRT512009	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT512008	hsa-miR-586	PAR-CLIP	20371350
MIRT512007	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT512011	hsa-miR-448	PAR-CLIP	20371350
MIRT512010	hsa-miR-598-3p	PAR-CLIP	20371350
MIRT512009	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT512007	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT512006	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT512011	hsa-miR-448	PAR-CLIP	21572407
MIRT558310	hsa-miR-6771-3p	PAR-CLIP	21572407
MIRT512006	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT512010	hsa-miR-598-3p	PAR-CLIP	21572407
MIRT512009	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT512008	hsa-miR-586	PAR-CLIP	21572407
MIRT523996	hsa-miR-6715a-3p	PAR-CLIP	21572407
MIRT512007	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT523995	hsa-miR-6715b-3p	PAR-CLIP	21572407
MIRT512011	hsa-miR-448	PAR-CLIP	21572407
MIRT512006	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT512010	hsa-miR-598-3p	PAR-CLIP	21572407
MIRT512009	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT512008	hsa-miR-586	PAR-CLIP	21572407
MIRT523996	hsa-miR-6715a-3p	PAR-CLIP	21572407
MIRT512007	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT523995	hsa-miR-6715b-3p	PAR-CLIP	21572407
MIRT512011	hsa-miR-448	PAR-CLIP	21572407
MIRT512006	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT512009	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT512008	hsa-miR-586	PAR-CLIP	21572407
MIRT512007	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT512011	hsa-miR-448	PAR-CLIP	23446348
MIRT512006	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT512010	hsa-miR-598-3p	PAR-CLIP	23446348
MIRT512009	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT512008	hsa-miR-586	PAR-CLIP	23446348
MIRT523996	hsa-miR-6715a-3p	PAR-CLIP	23446348
MIRT512007	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT523995	hsa-miR-6715b-3p	PAR-CLIP	23446348
MIRT512011	hsa-miR-448	PAR-CLIP	23446348
MIRT512010	hsa-miR-598-3p	PAR-CLIP	23446348
MIRT512009	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT512008	hsa-miR-586	PAR-CLIP	23446348
MIRT512007	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT512006	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT715184	hsa-miR-130a-3p	HITS-CLIP	19536157
MIRT715183	hsa-miR-130b-3p	HITS-CLIP	19536157
MIRT715182	hsa-miR-301a-3p	HITS-CLIP	19536157
MIRT715181	hsa-miR-301b-3p	HITS-CLIP	19536157
MIRT715180	hsa-miR-3666	HITS-CLIP	19536157
MIRT715179	hsa-miR-4295	HITS-CLIP	19536157
MIRT715178	hsa-miR-454-3p	HITS-CLIP	19536157
MIRT715177	hsa-miR-4709-5p	HITS-CLIP	19536157
MIRT715176	hsa-miR-5003-5p	HITS-CLIP	19536157
MIRT715175	hsa-miR-148a-3p	HITS-CLIP	19536157
MIRT715174	hsa-miR-148b-3p	HITS-CLIP	19536157
MIRT715173	hsa-miR-152-3p	HITS-CLIP	19536157
MIRT512011	hsa-miR-448	HITS-CLIP	21572407
MIRT512006	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT512010	hsa-miR-598-3p	HITS-CLIP	21572407
MIRT512009	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT512008	hsa-miR-586	HITS-CLIP	21572407
MIRT523996	hsa-miR-6715a-3p	HITS-CLIP	21572407
MIRT512007	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT523995	hsa-miR-6715b-3p	HITS-CLIP	21572407
MIRT512010	hsa-miR-598-3p	HITS-CLIP	21572407
MIRT512009	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT512007	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT512006	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT512011	hsa-miR-448	HITS-CLIP	23313552
MIRT512006	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT512009	hsa-miR-5011-5p	HITS-CLIP	23313552
MIRT512008	hsa-miR-586	HITS-CLIP	23313552
MIRT512007	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT512011	hsa-miR-448	HITS-CLIP	23824327
MIRT512010	hsa-miR-598-3p	HITS-CLIP	23824327
MIRT512009	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT512007	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT512006	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT512011	hsa-miR-448	PAR-CLIP	20371350
MIRT512006	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT512010	hsa-miR-598-3p	PAR-CLIP	20371350
MIRT512009	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT512008	hsa-miR-586	PAR-CLIP	20371350
MIRT512007	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT512011	hsa-miR-448	PAR-CLIP	20371350
MIRT512010	hsa-miR-598-3p	PAR-CLIP	20371350
MIRT512009	hsa-miR-5011-5p	PAR-CLIP	20371350
MIRT512007	hsa-miR-190a-3p	PAR-CLIP	20371350
MIRT512006	hsa-miR-1277-5p	PAR-CLIP	20371350
MIRT512011	hsa-miR-448	PAR-CLIP	21572407
MIRT558310	hsa-miR-6771-3p	PAR-CLIP	21572407
MIRT512006	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT512010	hsa-miR-598-3p	PAR-CLIP	21572407
MIRT512009	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT512008	hsa-miR-586	PAR-CLIP	21572407
MIRT523996	hsa-miR-6715a-3p	PAR-CLIP	21572407
MIRT512007	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT523995	hsa-miR-6715b-3p	PAR-CLIP	21572407
MIRT512011	hsa-miR-448	PAR-CLIP	21572407
MIRT512006	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT512010	hsa-miR-598-3p	PAR-CLIP	21572407
MIRT512009	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT512008	hsa-miR-586	PAR-CLIP	21572407
MIRT523996	hsa-miR-6715a-3p	PAR-CLIP	21572407
MIRT512007	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT523995	hsa-miR-6715b-3p	PAR-CLIP	21572407
MIRT512011	hsa-miR-448	PAR-CLIP	21572407
MIRT512006	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT512009	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT512008	hsa-miR-586	PAR-CLIP	21572407
MIRT512007	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT512011	hsa-miR-448	PAR-CLIP	23446348
MIRT512006	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT512010	hsa-miR-598-3p	PAR-CLIP	23446348
MIRT512009	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT512008	hsa-miR-586	PAR-CLIP	23446348
MIRT523996	hsa-miR-6715a-3p	PAR-CLIP	23446348
MIRT512007	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT523995	hsa-miR-6715b-3p	PAR-CLIP	23446348
MIRT512011	hsa-miR-448	PAR-CLIP	23446348
MIRT512010	hsa-miR-598-3p	PAR-CLIP	23446348
MIRT512009	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT512008	hsa-miR-586	PAR-CLIP	23446348
MIRT512007	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT512006	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT947206	hsa-miR-1197	CLIP-seq
MIRT947207	hsa-miR-1226	CLIP-seq
MIRT947208	hsa-miR-1253	CLIP-seq
MIRT947209	hsa-miR-125a-3p	CLIP-seq
MIRT947210	hsa-miR-127-5p	CLIP-seq
MIRT947211	hsa-miR-1286	CLIP-seq
MIRT947212	hsa-miR-1299	CLIP-seq
MIRT947213	hsa-miR-140-3p	CLIP-seq
MIRT947214	hsa-miR-151-3p	CLIP-seq
MIRT947215	hsa-miR-183	CLIP-seq
MIRT947216	hsa-miR-205	CLIP-seq
MIRT947217	hsa-miR-24	CLIP-seq
MIRT947218	hsa-miR-29a	CLIP-seq
MIRT947219	hsa-miR-29b	CLIP-seq
MIRT947220	hsa-miR-29c	CLIP-seq
MIRT947221	hsa-miR-3065-3p	CLIP-seq
MIRT947222	hsa-miR-3123	CLIP-seq
MIRT947223	hsa-miR-3130-3p	CLIP-seq
MIRT947224	hsa-miR-3163	CLIP-seq
MIRT947225	hsa-miR-3180-5p	CLIP-seq
MIRT947226	hsa-miR-3202	CLIP-seq
MIRT947227	hsa-miR-3614-3p	CLIP-seq
MIRT947228	hsa-miR-3616-3p	CLIP-seq
MIRT947229	hsa-miR-3667-3p	CLIP-seq
MIRT947230	hsa-miR-3689a-3p	CLIP-seq
MIRT947231	hsa-miR-3689c	CLIP-seq
MIRT947232	hsa-miR-376a	CLIP-seq
MIRT947233	hsa-miR-376b	CLIP-seq
MIRT947234	hsa-miR-3919	CLIP-seq
MIRT947235	hsa-miR-3928	CLIP-seq
MIRT947236	hsa-miR-3934	CLIP-seq
MIRT947237	hsa-miR-4259	CLIP-seq
MIRT947238	hsa-miR-4279	CLIP-seq
MIRT947239	hsa-miR-4292	CLIP-seq
MIRT947240	hsa-miR-4305	CLIP-seq
MIRT947241	hsa-miR-4308	CLIP-seq
MIRT947242	hsa-miR-4425	CLIP-seq
MIRT947243	hsa-miR-4436a	CLIP-seq
MIRT947244	hsa-miR-4436b-3p	CLIP-seq
MIRT947245	hsa-miR-4463	CLIP-seq
MIRT947246	hsa-miR-4499	CLIP-seq
MIRT947247	hsa-miR-4522	CLIP-seq
MIRT947248	hsa-miR-4533	CLIP-seq
MIRT947249	hsa-miR-4728-5p	CLIP-seq
MIRT947250	hsa-miR-4747-5p	CLIP-seq
MIRT947251	hsa-miR-4786-3p	CLIP-seq
MIRT947252	hsa-miR-548aa	CLIP-seq
MIRT947253	hsa-miR-570	CLIP-seq
MIRT947254	hsa-miR-634	CLIP-seq
MIRT947255	hsa-miR-645	CLIP-seq
MIRT947256	hsa-miR-764	CLIP-seq
MIRT947257	hsa-miR-875-3p	CLIP-seq
MIRT1980551	hsa-miR-1224-3p	CLIP-seq
MIRT1980552	hsa-miR-1273g	CLIP-seq
MIRT1980553	hsa-miR-1321	CLIP-seq
MIRT1980554	hsa-miR-2355-5p	CLIP-seq
MIRT1980555	hsa-miR-3120-5p	CLIP-seq
MIRT1980556	hsa-miR-3192	CLIP-seq
MIRT1980557	hsa-miR-4286	CLIP-seq
MIRT1980558	hsa-miR-4300	CLIP-seq
MIRT1980559	hsa-miR-4326	CLIP-seq
MIRT947244	hsa-miR-4436b-3p	CLIP-seq
MIRT1980560	hsa-miR-4527	CLIP-seq
MIRT1980561	hsa-miR-4659a-3p	CLIP-seq
MIRT1980562	hsa-miR-4659b-3p	CLIP-seq
MIRT1980563	hsa-miR-4719	CLIP-seq
MIRT1980564	hsa-miR-4731-3p	CLIP-seq
MIRT1980565	hsa-miR-4739	CLIP-seq
MIRT1980566	hsa-miR-4756-5p	CLIP-seq
MIRT1980567	hsa-miR-4778-3p	CLIP-seq
MIRT1980568	hsa-miR-4801	CLIP-seq
MIRT1980569	hsa-miR-548an	CLIP-seq
MIRT1980570	hsa-miR-605	CLIP-seq
MIRT1980571	hsa-miR-920	CLIP-seq
MIRT2215531	hsa-miR-1184	CLIP-seq
MIRT2215532	hsa-miR-1205	CLIP-seq
MIRT2215533	hsa-miR-1206	CLIP-seq
MIRT2215534	hsa-miR-1255a	CLIP-seq
MIRT2215535	hsa-miR-1255b	CLIP-seq
MIRT1980552	hsa-miR-1273g	CLIP-seq
MIRT2215536	hsa-miR-130a	CLIP-seq
MIRT2215537	hsa-miR-130b	CLIP-seq
MIRT2215538	hsa-miR-148a	CLIP-seq
MIRT2215539	hsa-miR-148b	CLIP-seq
MIRT2215540	hsa-miR-152	CLIP-seq
MIRT2215541	hsa-miR-2113	CLIP-seq
MIRT2215542	hsa-miR-2276	CLIP-seq
MIRT2215543	hsa-miR-2467-3p	CLIP-seq
MIRT2215544	hsa-miR-2964a-5p	CLIP-seq
MIRT947218	hsa-miR-29a	CLIP-seq
MIRT947219	hsa-miR-29b	CLIP-seq
MIRT947220	hsa-miR-29c	CLIP-seq
MIRT2215545	hsa-miR-301a	CLIP-seq
MIRT2215546	hsa-miR-301b	CLIP-seq
MIRT2215547	hsa-miR-3158-5p	CLIP-seq
MIRT947224	hsa-miR-3163	CLIP-seq
MIRT1980556	hsa-miR-3192	CLIP-seq
MIRT2215548	hsa-miR-323b-5p	CLIP-seq
MIRT2215549	hsa-miR-3591-3p	CLIP-seq
MIRT2215550	hsa-miR-3663-3p	CLIP-seq
MIRT2215551	hsa-miR-3678-3p	CLIP-seq
MIRT2215552	hsa-miR-4273	CLIP-seq
MIRT1980558	hsa-miR-4300	CLIP-seq
MIRT2215553	hsa-miR-454	CLIP-seq
MIRT2215554	hsa-miR-4659a-5p	CLIP-seq
MIRT2215555	hsa-miR-4659b-5p	CLIP-seq
MIRT2215556	hsa-miR-4677-5p	CLIP-seq
MIRT2215557	hsa-miR-4729	CLIP-seq
MIRT2215558	hsa-miR-4733-3p	CLIP-seq
MIRT2215559	hsa-miR-4772-3p	CLIP-seq
MIRT2215560	hsa-miR-4776-3p	CLIP-seq
MIRT2215561	hsa-miR-518a-5p	CLIP-seq
MIRT2215562	hsa-miR-527	CLIP-seq
MIRT2215563	hsa-miR-544	CLIP-seq
MIRT1980569	hsa-miR-548an	CLIP-seq
MIRT2215564	hsa-miR-548u	CLIP-seq
MIRT2215565	hsa-miR-579	CLIP-seq
MIRT1980571	hsa-miR-920	CLIP-seq
MIRT947209	hsa-miR-125a-3p	CLIP-seq
MIRT2387146	hsa-miR-4520a-3p	CLIP-seq
MIRT2387147	hsa-miR-4520b-3p	CLIP-seq
MIRT2387148	hsa-miR-4529-3p	CLIP-seq
MIRT2387149	hsa-miR-552	CLIP-seq
MIRT2387150	hsa-miR-9	CLIP-seq
MIRT947228	hsa-miR-3616-3p	CLIP-seq
MIRT2448578	hsa-miR-3939	CLIP-seq
MIRT2448579	hsa-miR-3978	CLIP-seq
MIRT2448580	hsa-miR-4311	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004842	Function	Ubiquitin-protein transferase activity	TAS
GO:0005654	Component	Nucleoplasm	IBA
GO:0005737	Component	Cytoplasm	IC	27692986
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IDA	35793002
GO:0005829	Component	Cytosol	TAS
GO:0007219	Process	Notch signaling pathway	IBA
GO:0007219	Process	Notch signaling pathway	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0010498	Process	Proteasomal protein catabolic process	IDA	35793002
GO:0016567	Process	Protein ubiquitination	IBA
GO:0016567	Process	Protein ubiquitination	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0032479	Process	Regulation of type I interferon production	TAS
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IDA	27692986
GO:0045087	Process	Innate immune response	IDA	25636800
GO:0045824	Process	Negative regulation of innate immune response	IDA	27692986, 35793002
GO:0046872	Function	Metal ion binding	IEA
GO:0061630	Function	Ubiquitin protein ligase activity	IBA
GO:0061630	Function	Ubiquitin protein ligase activity	IDA	35793002
GO:0061630	Function	Ubiquitin protein ligase activity	IEA
GO:0070936	Process	Protein K48-linked ubiquitination	IDA	27692986
GO:0140374	Process	Antiviral innate immune response	IDA	14703513

Other IDs

• MIM: 616110
• HGNC: 29151
• e!Ensembl: ENSG00000110042

Protein

• UniProt ID: Q9Y2E6
• Protein name: E3 ubiquitin-protein ligase DTX4 (EC 2.3.2.27) (Protein deltex-4) (Deltex4) (RING finger protein 155) (RING-type E3 ubiquitin transferase DTX4)
• Protein function: Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations (By similarity). Functions as a ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubi
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02825	WWE	8 → 78	WWE domain	Family
  PF02825	WWE	91 → 155	WWE domain	Family
  PF00097	zf-C3HC4	409 → 467	Zinc finger, C3HC4 type (RING finger)	Domain
  PF18102	DTC	475 → 609	Deltex C-terminal domain	Domain

• Sequence:

  MLLASAVVVWEWLNEHGRWRPYSPAVSHHIEAVVRAGPRAGGSVVLGQVDSRLAPYIIDL
  QSMNQFRQDTGTLRPVRRNYYDPSSAPGKGVVWEWENDNGSWTPYDMEVGITIQHAYEKQ
  HPWIDLTSIGFSYVIDFNTMGQINRQTQRQRRVRRRLDLIYPMVTGTLPKAQSWPVSPGP
  ATSPPMSPCSCPQCVLVMSVKAAVVNGSTGPLQLPVTRKNMPPPGVVKLPPLPGSGAKPL
  DSTGTIRGPLKTAPSQVIRRQASSMPTGTTMGSPASPPGPNSKTGRVALATLNRTNLQRL
  AIAQSRVLIASGVPTVPVKNLNGSSPVNPALAGITGILMSAAGLPVCLTRPPKLVLHPPP
  VSKSEIKSIPGVSNTSRKTTKKQAKKGKTPEEVLKKYLQKVRHPPDEDCTICMERLTAPS
  GYKGPQPTVKPDLVGKLSRCGHVYHIYCLVAMYNNGNKDGSLQCPTCKTIYGVKTGTQPP
  GKMEYHLIPHSLPGHPDCKTIRIIYSIPPGIQGPEHPNPGKSFSARGFPRHCYLPDSEKG
  RKVLKLLLVAWDRRLIFAIGTSSTTGESDTVIWNEVHHKTEFGSNLTGHGYPDANYLDNV
  LAELAAQGISEDSTAQEKD

• Sequence length: 619

Pathways

KEGG:

Notch signaling pathway

Reactome:

IRF3 mediated activation of type 1 IFN
Activated NOTCH1 Transmits Signal to the Nucleus
Regulation of innate immune responses to cytosolic DNA
IRF3-mediated induction of type I IFN