JMJD6 (jumonji domain containing 6, arginine demethylase and lysine hydroxylase)

Gene

• Entrez ID: 23210
• Gene name: Jumonji domain containing 6, arginine demethylase and lysine hydroxylase
• Gene symbol: JMJD6
• Synonyms (NCBI Gene): PSR, PTDSR, PTDSR1
• Chromosome: 17
• Chromosome location: 17q25.1
• Summary: This gene encodes a nuclear protein with a JmjC domain. JmjC domain-containing proteins are predicted to function as protein hydroxylases or histone demethylases. This protein was first identified as a putative phosphatidylserine receptor involved in phag

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT049750	hsa-miR-92a-3p	CLASH	23622248
MIRT041794	hsa-miR-484	CLASH	23622248
MIRT052729	hsa-miR-1260b	CLASH	23622248
MIRT1076993	hsa-let-7a	CLIP-seq
MIRT1076994	hsa-let-7b	CLIP-seq
MIRT1076995	hsa-let-7c	CLIP-seq
MIRT1076996	hsa-let-7d	CLIP-seq
MIRT1076997	hsa-let-7e	CLIP-seq
MIRT1076998	hsa-let-7f	CLIP-seq
MIRT1076999	hsa-let-7g	CLIP-seq
MIRT1077000	hsa-let-7i	CLIP-seq
MIRT1077001	hsa-miR-1227	CLIP-seq
MIRT1077002	hsa-miR-1228	CLIP-seq
MIRT1077003	hsa-miR-1245	CLIP-seq
MIRT1077004	hsa-miR-1272	CLIP-seq
MIRT1077005	hsa-miR-1294	CLIP-seq
MIRT1077006	hsa-miR-1303	CLIP-seq
MIRT1077007	hsa-miR-194	CLIP-seq
MIRT1077008	hsa-miR-202	CLIP-seq
MIRT1077009	hsa-miR-3130-3p	CLIP-seq
MIRT1077010	hsa-miR-3145-5p	CLIP-seq
MIRT1077011	hsa-miR-3148	CLIP-seq
MIRT1077012	hsa-miR-3149	CLIP-seq
MIRT1077013	hsa-miR-3176	CLIP-seq
MIRT1077014	hsa-miR-3187-3p	CLIP-seq
MIRT1077015	hsa-miR-3545-3p	CLIP-seq
MIRT1077016	hsa-miR-3612	CLIP-seq
MIRT1077017	hsa-miR-3622a-5p	CLIP-seq
MIRT1077018	hsa-miR-3662	CLIP-seq
MIRT1077019	hsa-miR-3663-5p	CLIP-seq
MIRT1077020	hsa-miR-3690	CLIP-seq
MIRT1077021	hsa-miR-378	CLIP-seq
MIRT1077022	hsa-miR-378b	CLIP-seq
MIRT1077023	hsa-miR-378c	CLIP-seq
MIRT1077024	hsa-miR-378d	CLIP-seq
MIRT1077025	hsa-miR-378e	CLIP-seq
MIRT1077026	hsa-miR-378f	CLIP-seq
MIRT1077027	hsa-miR-378h	CLIP-seq
MIRT1077028	hsa-miR-378i	CLIP-seq
MIRT1077029	hsa-miR-3922-3p	CLIP-seq
MIRT1077030	hsa-miR-3934	CLIP-seq
MIRT1077031	hsa-miR-411	CLIP-seq
MIRT1077032	hsa-miR-422a	CLIP-seq
MIRT1077033	hsa-miR-4252	CLIP-seq
MIRT1077034	hsa-miR-4254	CLIP-seq
MIRT1077035	hsa-miR-4435	CLIP-seq
MIRT1077036	hsa-miR-4458	CLIP-seq
MIRT1077037	hsa-miR-4459	CLIP-seq
MIRT1077038	hsa-miR-4463	CLIP-seq
MIRT1077039	hsa-miR-4476	CLIP-seq
MIRT1077040	hsa-miR-4500	CLIP-seq
MIRT1077041	hsa-miR-455-5p	CLIP-seq
MIRT1077042	hsa-miR-4635	CLIP-seq
MIRT1077043	hsa-miR-4670-3p	CLIP-seq
MIRT1077044	hsa-miR-4680-5p	CLIP-seq
MIRT1077045	hsa-miR-4695-5p	CLIP-seq
MIRT1077046	hsa-miR-4701-5p	CLIP-seq
MIRT1077047	hsa-miR-4715-3p	CLIP-seq
MIRT1077048	hsa-miR-4731-3p	CLIP-seq
MIRT1077049	hsa-miR-4735-5p	CLIP-seq
MIRT1077050	hsa-miR-4755-3p	CLIP-seq
MIRT1077051	hsa-miR-4766-5p	CLIP-seq
MIRT1077052	hsa-miR-4775	CLIP-seq
MIRT1077053	hsa-miR-4794	CLIP-seq
MIRT1077054	hsa-miR-4801	CLIP-seq
MIRT1077055	hsa-miR-483-5p	CLIP-seq
MIRT1077056	hsa-miR-488	CLIP-seq
MIRT1077057	hsa-miR-508-5p	CLIP-seq
MIRT1077058	hsa-miR-5095	CLIP-seq
MIRT1077059	hsa-miR-5096	CLIP-seq
MIRT1077060	hsa-miR-548a-3p	CLIP-seq
MIRT1077061	hsa-miR-548ag	CLIP-seq
MIRT1077062	hsa-miR-548ai	CLIP-seq
MIRT1077063	hsa-miR-548e	CLIP-seq
MIRT1077064	hsa-miR-548f	CLIP-seq
MIRT1077065	hsa-miR-548g	CLIP-seq
MIRT1077066	hsa-miR-548s	CLIP-seq
MIRT1077067	hsa-miR-549	CLIP-seq
MIRT1077068	hsa-miR-552	CLIP-seq
MIRT1077069	hsa-miR-561	CLIP-seq
MIRT1077070	hsa-miR-574-5p	CLIP-seq
MIRT1077071	hsa-miR-588	CLIP-seq
MIRT1077072	hsa-miR-590-3p	CLIP-seq
MIRT1077073	hsa-miR-640	CLIP-seq
MIRT1077074	hsa-miR-648	CLIP-seq
MIRT1077075	hsa-miR-650	CLIP-seq
MIRT1077076	hsa-miR-653	CLIP-seq
MIRT1077077	hsa-miR-665	CLIP-seq
MIRT1077078	hsa-miR-767-3p	CLIP-seq
MIRT1077079	hsa-miR-877	CLIP-seq
MIRT1077080	hsa-miR-98	CLIP-seq
MIRT2019140	hsa-miR-23a	CLIP-seq
MIRT2019141	hsa-miR-23b	CLIP-seq
MIRT2019142	hsa-miR-23c	CLIP-seq
MIRT2019143	hsa-miR-4686	CLIP-seq
MIRT2019144	hsa-miR-4753-3p	CLIP-seq
MIRT2251060	hsa-miR-1972	CLIP-seq
MIRT2251061	hsa-miR-3654	CLIP-seq
MIRT2389550	hsa-miR-33a	CLIP-seq
MIRT2389551	hsa-miR-33b	CLIP-seq
MIRT2019143	hsa-miR-4686	CLIP-seq
MIRT1077001	hsa-miR-1227	CLIP-seq
MIRT1077002	hsa-miR-1228	CLIP-seq
MIRT2452080	hsa-miR-217	CLIP-seq
MIRT1077012	hsa-miR-3149	CLIP-seq
MIRT2452081	hsa-miR-3199	CLIP-seq
MIRT1077031	hsa-miR-411	CLIP-seq
MIRT2452082	hsa-miR-4310	CLIP-seq
MIRT2452083	hsa-miR-4418	CLIP-seq
MIRT2452084	hsa-miR-4438	CLIP-seq
MIRT1077041	hsa-miR-455-5p	CLIP-seq
MIRT2452085	hsa-miR-4699-3p	CLIP-seq
MIRT1077047	hsa-miR-4715-3p	CLIP-seq
MIRT1077049	hsa-miR-4735-5p	CLIP-seq
MIRT1077052	hsa-miR-4775	CLIP-seq
MIRT1077053	hsa-miR-4794	CLIP-seq
MIRT1077055	hsa-miR-483-5p	CLIP-seq
MIRT2452086	hsa-miR-509-3-5p	CLIP-seq
MIRT1077058	hsa-miR-5095	CLIP-seq
MIRT2452087	hsa-miR-509-5p	CLIP-seq
MIRT1077072	hsa-miR-590-3p	CLIP-seq
MIRT1077002	hsa-miR-1228	CLIP-seq
MIRT1077012	hsa-miR-3149	CLIP-seq
MIRT1077014	hsa-miR-3187-3p	CLIP-seq
MIRT1077031	hsa-miR-411	CLIP-seq
MIRT1077035	hsa-miR-4435	CLIP-seq
MIRT1077046	hsa-miR-4701-5p	CLIP-seq
MIRT1077047	hsa-miR-4715-3p	CLIP-seq
MIRT1077049	hsa-miR-4735-5p	CLIP-seq
MIRT1077052	hsa-miR-4775	CLIP-seq
MIRT1077053	hsa-miR-4794	CLIP-seq
MIRT1077055	hsa-miR-483-5p	CLIP-seq
MIRT1077059	hsa-miR-5096	CLIP-seq
MIRT1077066	hsa-miR-548s	CLIP-seq
MIRT1077071	hsa-miR-588	CLIP-seq
MIRT1077072	hsa-miR-590-3p	CLIP-seq
MIRT2554472	hsa-miR-1202	CLIP-seq
MIRT2554473	hsa-miR-1207-3p	CLIP-seq
MIRT2554474	hsa-miR-122	CLIP-seq
MIRT1077001	hsa-miR-1227	CLIP-seq
MIRT1077002	hsa-miR-1228	CLIP-seq
MIRT2554475	hsa-miR-1248	CLIP-seq
MIRT2554476	hsa-miR-1257	CLIP-seq
MIRT2554477	hsa-miR-1260	CLIP-seq
MIRT2554478	hsa-miR-1270	CLIP-seq
MIRT1077004	hsa-miR-1272	CLIP-seq
MIRT2554479	hsa-miR-1273g	CLIP-seq
MIRT2554480	hsa-miR-1291	CLIP-seq
MIRT2554481	hsa-miR-1305	CLIP-seq
MIRT2554482	hsa-miR-149	CLIP-seq
MIRT2554483	hsa-miR-1587	CLIP-seq
MIRT2554484	hsa-miR-188-3p	CLIP-seq
MIRT2554485	hsa-miR-1915	CLIP-seq
MIRT2554486	hsa-miR-208a	CLIP-seq
MIRT2554487	hsa-miR-208b	CLIP-seq
MIRT2554488	hsa-miR-2276	CLIP-seq
MIRT2554489	hsa-miR-298	CLIP-seq
MIRT2554490	hsa-miR-3120-3p	CLIP-seq
MIRT2554491	hsa-miR-3136-5p	CLIP-seq
MIRT2554492	hsa-miR-3137	CLIP-seq
MIRT1077010	hsa-miR-3145-5p	CLIP-seq
MIRT1077012	hsa-miR-3149	CLIP-seq
MIRT2554493	hsa-miR-3156-3p	CLIP-seq
MIRT2554494	hsa-miR-3160-3p	CLIP-seq
MIRT2554495	hsa-miR-3182	CLIP-seq
MIRT2554496	hsa-miR-3185	CLIP-seq
MIRT1077014	hsa-miR-3187-3p	CLIP-seq
MIRT2554497	hsa-miR-3190	CLIP-seq
MIRT2554498	hsa-miR-3194-5p	CLIP-seq
MIRT2452081	hsa-miR-3199	CLIP-seq
MIRT2554499	hsa-miR-328	CLIP-seq
MIRT1077016	hsa-miR-3612	CLIP-seq
MIRT2554500	hsa-miR-3617	CLIP-seq
MIRT2554501	hsa-miR-3620	CLIP-seq
MIRT1077017	hsa-miR-3622a-5p	CLIP-seq
MIRT2554502	hsa-miR-3671	CLIP-seq
MIRT2554503	hsa-miR-3682-3p	CLIP-seq
MIRT2554504	hsa-miR-3686	CLIP-seq
MIRT2554505	hsa-miR-3689a-3p	CLIP-seq
MIRT2554506	hsa-miR-3689c	CLIP-seq
MIRT2554507	hsa-miR-371-5p	CLIP-seq
MIRT2554508	hsa-miR-3911	CLIP-seq
MIRT2554509	hsa-miR-3942-5p	CLIP-seq
MIRT2554510	hsa-miR-3944-5p	CLIP-seq
MIRT2554511	hsa-miR-3972	CLIP-seq
MIRT1077031	hsa-miR-411	CLIP-seq
MIRT2554512	hsa-miR-423-3p	CLIP-seq
MIRT1077033	hsa-miR-4252	CLIP-seq
MIRT2554513	hsa-miR-4265	CLIP-seq
MIRT2554514	hsa-miR-4276	CLIP-seq
MIRT2554515	hsa-miR-4277	CLIP-seq
MIRT2554516	hsa-miR-4279	CLIP-seq
MIRT2554517	hsa-miR-4283	CLIP-seq
MIRT2554518	hsa-miR-4296	CLIP-seq
MIRT2554519	hsa-miR-4301	CLIP-seq
MIRT2554520	hsa-miR-4302	CLIP-seq
MIRT2554521	hsa-miR-4312	CLIP-seq
MIRT2554522	hsa-miR-4322	CLIP-seq
MIRT2554523	hsa-miR-4417	CLIP-seq
MIRT2554524	hsa-miR-4420	CLIP-seq
MIRT1077035	hsa-miR-4435	CLIP-seq
MIRT2554525	hsa-miR-4436b-5p	CLIP-seq
MIRT2452084	hsa-miR-4438	CLIP-seq
MIRT2554526	hsa-miR-4439	CLIP-seq
MIRT2554527	hsa-miR-4452	CLIP-seq
MIRT1077037	hsa-miR-4459	CLIP-seq
MIRT2554528	hsa-miR-4462	CLIP-seq
MIRT2554529	hsa-miR-4477a	CLIP-seq
MIRT2554530	hsa-miR-4487	CLIP-seq
MIRT2554531	hsa-miR-4489	CLIP-seq
MIRT2554532	hsa-miR-4492	CLIP-seq
MIRT2554533	hsa-miR-4498	CLIP-seq
MIRT2554534	hsa-miR-4502	CLIP-seq
MIRT2554535	hsa-miR-4531	CLIP-seq
MIRT1077041	hsa-miR-455-5p	CLIP-seq
MIRT2554536	hsa-miR-4656	CLIP-seq
MIRT2554537	hsa-miR-4659a-3p	CLIP-seq
MIRT2554538	hsa-miR-4659b-3p	CLIP-seq
MIRT2554539	hsa-miR-4675	CLIP-seq
MIRT2554540	hsa-miR-4685-5p	CLIP-seq
MIRT2554541	hsa-miR-4695-3p	CLIP-seq
MIRT1077045	hsa-miR-4695-5p	CLIP-seq
MIRT2554542	hsa-miR-4696	CLIP-seq
MIRT2554543	hsa-miR-4698	CLIP-seq
MIRT1077046	hsa-miR-4701-5p	CLIP-seq
MIRT2554544	hsa-miR-4703-5p	CLIP-seq
MIRT2554545	hsa-miR-4704-3p	CLIP-seq
MIRT1077047	hsa-miR-4715-3p	CLIP-seq
MIRT2554546	hsa-miR-4722-3p	CLIP-seq
MIRT2554547	hsa-miR-4726-3p	CLIP-seq
MIRT2554548	hsa-miR-4727-3p	CLIP-seq
MIRT2554549	hsa-miR-4728-5p	CLIP-seq
MIRT1077048	hsa-miR-4731-3p	CLIP-seq
MIRT2554550	hsa-miR-4731-5p	CLIP-seq
MIRT1077049	hsa-miR-4735-5p	CLIP-seq
MIRT2554551	hsa-miR-4741	CLIP-seq
MIRT2554552	hsa-miR-4762-5p	CLIP-seq
MIRT2554553	hsa-miR-4772-3p	CLIP-seq
MIRT1077052	hsa-miR-4775	CLIP-seq
MIRT1077053	hsa-miR-4794	CLIP-seq
MIRT1077054	hsa-miR-4801	CLIP-seq
MIRT1077055	hsa-miR-483-5p	CLIP-seq
MIRT2554554	hsa-miR-499-5p	CLIP-seq
MIRT1077057	hsa-miR-508-5p	CLIP-seq
MIRT1077058	hsa-miR-5095	CLIP-seq
MIRT1077059	hsa-miR-5096	CLIP-seq
MIRT2554555	hsa-miR-545	CLIP-seq
MIRT2554556	hsa-miR-548p	CLIP-seq
MIRT1077066	hsa-miR-548s	CLIP-seq
MIRT1077067	hsa-miR-549	CLIP-seq
MIRT2554557	hsa-miR-558	CLIP-seq
MIRT2554558	hsa-miR-563	CLIP-seq
MIRT1077070	hsa-miR-574-5p	CLIP-seq
MIRT2554559	hsa-miR-586	CLIP-seq
MIRT1077071	hsa-miR-588	CLIP-seq
MIRT1077072	hsa-miR-590-3p	CLIP-seq
MIRT2554560	hsa-miR-607	CLIP-seq
MIRT2554561	hsa-miR-620	CLIP-seq
MIRT2554562	hsa-miR-624	CLIP-seq
MIRT2554563	hsa-miR-634	CLIP-seq
MIRT2554564	hsa-miR-641	CLIP-seq
MIRT2554565	hsa-miR-642a	CLIP-seq
MIRT2554566	hsa-miR-642b	CLIP-seq
MIRT1077074	hsa-miR-648	CLIP-seq
MIRT1077075	hsa-miR-650	CLIP-seq
MIRT1077077	hsa-miR-665	CLIP-seq
MIRT2554567	hsa-miR-7	CLIP-seq
MIRT2554568	hsa-miR-762	CLIP-seq
MIRT2554569	hsa-miR-887	CLIP-seq
MIRT2554570	hsa-miR-892b	CLIP-seq
MIRT2554571	hsa-miR-943	CLIP-seq
MIRT2554572	hsa-miR-944	CLIP-seq
MIRT2554473	hsa-miR-1207-3p	CLIP-seq
MIRT2554474	hsa-miR-122	CLIP-seq
MIRT1077001	hsa-miR-1227	CLIP-seq
MIRT1077002	hsa-miR-1228	CLIP-seq
MIRT2554475	hsa-miR-1248	CLIP-seq
MIRT2554477	hsa-miR-1260	CLIP-seq
MIRT2554478	hsa-miR-1270	CLIP-seq
MIRT1077004	hsa-miR-1272	CLIP-seq
MIRT2554483	hsa-miR-1587	CLIP-seq
MIRT2554484	hsa-miR-188-3p	CLIP-seq
MIRT2554489	hsa-miR-298	CLIP-seq
MIRT2683111	hsa-miR-3135b	CLIP-seq
MIRT2554492	hsa-miR-3137	CLIP-seq
MIRT1077010	hsa-miR-3145-5p	CLIP-seq
MIRT1077012	hsa-miR-3149	CLIP-seq
MIRT2683112	hsa-miR-3154	CLIP-seq
MIRT2554493	hsa-miR-3156-3p	CLIP-seq
MIRT2554495	hsa-miR-3182	CLIP-seq
MIRT2554496	hsa-miR-3185	CLIP-seq
MIRT2452081	hsa-miR-3199	CLIP-seq
MIRT1077016	hsa-miR-3612	CLIP-seq
MIRT1077017	hsa-miR-3622a-5p	CLIP-seq
MIRT2683113	hsa-miR-3652	CLIP-seq
MIRT2683114	hsa-miR-3667-3p	CLIP-seq
MIRT2554503	hsa-miR-3682-3p	CLIP-seq
MIRT2554504	hsa-miR-3686	CLIP-seq
MIRT2683115	hsa-miR-3691-3p	CLIP-seq
MIRT2554510	hsa-miR-3944-5p	CLIP-seq
MIRT1077031	hsa-miR-411	CLIP-seq
MIRT1077033	hsa-miR-4252	CLIP-seq
MIRT2554513	hsa-miR-4265	CLIP-seq
MIRT2554514	hsa-miR-4276	CLIP-seq
MIRT2554515	hsa-miR-4277	CLIP-seq
MIRT2554518	hsa-miR-4296	CLIP-seq
MIRT2554519	hsa-miR-4301	CLIP-seq
MIRT2554520	hsa-miR-4302	CLIP-seq
MIRT2554522	hsa-miR-4322	CLIP-seq
MIRT2554523	hsa-miR-4417	CLIP-seq
MIRT2683116	hsa-miR-4430	CLIP-seq
MIRT1077035	hsa-miR-4435	CLIP-seq
MIRT2452084	hsa-miR-4438	CLIP-seq
MIRT1077037	hsa-miR-4459	CLIP-seq
MIRT2554532	hsa-miR-4492	CLIP-seq
MIRT2554533	hsa-miR-4498	CLIP-seq
MIRT2554534	hsa-miR-4502	CLIP-seq
MIRT2554535	hsa-miR-4531	CLIP-seq
MIRT1077041	hsa-miR-455-5p	CLIP-seq
MIRT2554536	hsa-miR-4656	CLIP-seq
MIRT2554537	hsa-miR-4659a-3p	CLIP-seq
MIRT2554538	hsa-miR-4659b-3p	CLIP-seq
MIRT2554539	hsa-miR-4675	CLIP-seq
MIRT1077045	hsa-miR-4695-5p	CLIP-seq
MIRT2683117	hsa-miR-4700-3p	CLIP-seq
MIRT2554545	hsa-miR-4704-3p	CLIP-seq
MIRT1077047	hsa-miR-4715-3p	CLIP-seq
MIRT1077048	hsa-miR-4731-3p	CLIP-seq
MIRT1077049	hsa-miR-4735-5p	CLIP-seq
MIRT2554551	hsa-miR-4741	CLIP-seq
MIRT1077052	hsa-miR-4775	CLIP-seq
MIRT2683118	hsa-miR-4789-3p	CLIP-seq
MIRT1077053	hsa-miR-4794	CLIP-seq
MIRT1077054	hsa-miR-4801	CLIP-seq
MIRT1077055	hsa-miR-483-5p	CLIP-seq
MIRT1077057	hsa-miR-508-5p	CLIP-seq
MIRT1077058	hsa-miR-5095	CLIP-seq
MIRT1077059	hsa-miR-5096	CLIP-seq
MIRT1077067	hsa-miR-549	CLIP-seq
MIRT1077070	hsa-miR-574-5p	CLIP-seq
MIRT2554559	hsa-miR-586	CLIP-seq
MIRT1077072	hsa-miR-590-3p	CLIP-seq
MIRT2554561	hsa-miR-620	CLIP-seq
MIRT2554562	hsa-miR-624	CLIP-seq
MIRT2554566	hsa-miR-642b	CLIP-seq
MIRT1077074	hsa-miR-648	CLIP-seq
MIRT1077075	hsa-miR-650	CLIP-seq
MIRT1077077	hsa-miR-665	CLIP-seq
MIRT2554568	hsa-miR-762	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001568	Process	Blood vessel development	IEA
GO:0001822	Process	Kidney development	IEA
GO:0002040	Process	Sprouting angiogenesis	IEA
GO:0002040	Process	Sprouting angiogenesis	ISS
GO:0003723	Function	RNA binding	IEA
GO:0003723	Function	RNA binding	TAS	21060799
GO:0003727	Function	Single-stranded RNA binding	IDA	20679243, 29176719
GO:0005506	Function	Iron ion binding	IDA	20679243
GO:0005515	Function	Protein binding	IPI	19574390, 21555454, 23455924, 24360279, 24498420, 24667498, 25416956, 29176719, 30698747, 32296183, 33961781
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	14729065, 17534701
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	IMP	21555454
GO:0005634	Component	Nucleus	ISS	33443146
GO:0005654	Component	Nucleoplasm	IDA	21060799
GO:0005654	Component	Nucleoplasm	IEA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005730	Component	Nucleolus	IDA	21060799
GO:0005730	Component	Nucleolus	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	24498420
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IEA
GO:0005886	Component	Plasma membrane	IEA
GO:0006325	Process	Chromatin organization	IEA
GO:0006338	Process	Chromatin remodeling	IDA	17947579
GO:0006397	Process	MRNA processing	IEA
GO:0006909	Process	Phagocytosis	IBA
GO:0007166	Process	Cell surface receptor signaling pathway	IEA
GO:0007507	Process	Heart development	IEA
GO:0008380	Process	RNA splicing	IEA
GO:0016491	Function	Oxidoreductase activity	IEA
GO:0018395	Process	Peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	IDA	19574390
GO:0030154	Process	Cell differentiation	IEA
GO:0030324	Process	Lung development	IEA
GO:0032452	Function	Histone demethylase activity	IDA	24498420
GO:0032452	Function	Histone demethylase activity	TAS
GO:0032463	Process	Negative regulation of protein homooligomerization	IEA
GO:0032463	Process	Negative regulation of protein homooligomerization	ISS	33443146
GO:0033077	Process	T cell differentiation in thymus	IEA
GO:0033746	Function	Histone H3R2 demethylase activity	IDA	17947579
GO:0033749	Function	Histone H4R3 demethylase activity	IBA
GO:0033749	Function	Histone H4R3 demethylase activity	IDA	17947579, 24360279
GO:0035513	Process	Oxidative RNA demethylation	IDA	24360279
GO:0035515	Function	Oxidative RNA demethylase activity	IMP	24360279
GO:0038023	Function	Signaling receptor activity	IEA
GO:0042116	Process	Macrophage activation	IEA
GO:0042802	Function	Identical protein binding	IDA	17534701
GO:0042802	Function	Identical protein binding	IEA
GO:0042802	Function	Identical protein binding	IPI	24360279
GO:0043277	Process	Apoptotic cell clearance	IEA
GO:0043654	Process	Recognition of apoptotic cell	IEA
GO:0045893	Process	Positive regulation of DNA-templated transcription	IMP	21555454
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	24360279
GO:0046872	Function	Metal ion binding	IEA
GO:0048024	Process	Regulation of mRNA splicing, via spliceosome	IEA
GO:0048024	Process	Regulation of mRNA splicing, via spliceosome	IMP	19574390
GO:0048821	Process	Erythrocyte development	IEA
GO:0051213	Function	Dioxygenase activity	IEA
GO:0051260	Process	Protein homooligomerization	IDA	22189873, 24360279
GO:0060041	Process	Retina development in camera-type eye	IEA
GO:0070815	Function	Peptidyl-lysine 5-dioxygenase activity	EXP	23303181
GO:0070815	Function	Peptidyl-lysine 5-dioxygenase activity	IDA	19574390, 22189873
GO:0070815	Function	Peptidyl-lysine 5-dioxygenase activity	IEA
GO:0106140	Function	P-TEFb complex binding	IBA
GO:0106140	Function	P-TEFb complex binding	IDA	24360279
GO:0140457	Function	Protein demethylase activity	IDA	24498420
GO:0140537	Function	Transcription regulator activator activity	IMP	21555454
GO:0140694	Process	Membraneless organelle assembly	IEA
GO:0140694	Process	Membraneless organelle assembly	ISS	33443146
GO:1990904	Component	Ribonucleoprotein complex	IEA

Other IDs

• MIM: 604914
• HGNC: 19355
• e!Ensembl: ENSG00000070495

Protein

• UniProt ID: Q6NYC1
• Protein name: Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (EC 1.14.11.-) (Histone arginine demethylase JMJD6) (JmjC domain-containing protein 6) (Jumonji domain-containing protein 6) (Lysyl-hydroxylase JMJD6) (Peptide-lysine 5-dioxygenase JMJD6) (Phos
• Protein function: Dioxygenase that can both act as a arginine demethylase and a lysyl-hydroxylase (PubMed:17947579, PubMed:20684070, PubMed:21060799, PubMed:22189873, PubMed:24498420). Acts as a lysyl-hydroxylase that catalyzes 5-hydroxylation on specific lysine
• PDB: 3K2O, 3LD8, 3LDB, 6BNH, 6GDY, 6MEV
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02373	JmjC	174 → 288	JmjC domain, hydroxylase	Domain

• Tissue specificity: TISSUE SPECIFICITY: Highly expressed in the heart, skeletal muscle and kidney. Expressed at moderate or low level in brain, placenta, lung, liver, pancreas, spleen, thymus, prostate, testis and ovary. Up-regulated in many patients with chronic pancreatiti
• Sequence:

  MNHKSKKRIREAKRSARPELKDSLDWTRHNYYESFSLSPAAVADNVERADALQLSVEEFV
  ERYERPYKPVVLLNAQEGWSAQEKWTLERLKRKYRNQKFKCGEDNDGYSVKMKMKYYIEY
  MESTRDDSPLYIFDSSYGEHPKRRKLLEDYKVPKFFTDDLFQYAGEKRRPPYRWFVMGPP
  RSGTGIHIDPLGTSAWNALVQGHKRWCLFPTSTPRELIKVTRDEGGNQQDEAITWFNVIY
  PRTQLPTWPPEFKPLEILQKPGETVFVPGGWWHVVLNLDTTIAITQNFASSTNFPVVWHK
  TVRGRPKLSRKWYRILKQEHPELAVLADSVDLQESTGIASDSSSDSSSSSSSSSSDSDSE
  CESGSEGDGTVHRRKKRRTCSMVGNGDTTSQDDCVSKERSSSR

• Sequence length: 403

Pathways

Reactome:

HDMs demethylate histones