Gene Gene information from NCBI Gene database.
Entrez ID 23208
Gene name Synaptotagmin 11
Gene symbol SYT11
Synonyms (NCBI Gene)
SYT12sytXI
Chromosome 1
Chromosome location 1q22
Summary This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that are known calcium sensors and mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. The encoded protein is a
miRNA miRNA information provided by mirtarbase database.
769
miRTarBase ID miRNA Experiments Reference
MIRT051123 hsa-miR-16-5p CLASH 23622248
MIRT047413 hsa-miR-10b-5p CLASH 23622248
MIRT665984 hsa-miR-1273d HITS-CLIP 23824327
MIRT665983 hsa-miR-3675-3p HITS-CLIP 23824327
MIRT665982 hsa-miR-6849-3p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
97
GO ID Ontology Definition Evidence Reference
GO:0000149 Function SNARE binding IBA
GO:0000149 Function SNARE binding IEA
GO:0001778 Process Plasma membrane repair IEA
GO:0001778 Process Plasma membrane repair ISS
GO:0001818 Process Negative regulation of cytokine production IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
608741 19239 ENSG00000132718
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9BT88
Protein name Synaptotagmin-11 (Synaptotagmin XI) (SytXI)
Protein function Synaptotagmin family member involved in vesicular and membrane trafficking which does not bind Ca(2+). Inhibits clathrin-mediated and bulk endocytosis, functions to ensure precision in vesicle retrieval. Plays an important role in dopamine trans
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00168 C2 172 279 C2 domain Domain
PF00168 C2 306 414 C2 domain Domain
Sequence
MAEITNIRPSFDVSPVVAGLIGASVLVVCVSVTVFVWSCCHQQAEKKQKNPPYKFIHMLK
GISIYPETLSNKKKIIKVRRDKDGPGREGGRRNLLVDAAEAGLLSRDKDPRGPSSGSCID
QLPIKMDYGEELRSPITSLTPGESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQE
AHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDL
VLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTR
DIIKRNIQKCISRGELQVSLS
YQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFN
ESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREV
CESPRK
PVAKWHSLSEY
Sequence length 431
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis