Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
23201
Gene name Gene Name - the full gene name approved by the HGNC.
Family with sequence similarity 168 member A
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
FAM168A
Synonyms (NCBI Gene) Gene synonyms aliases
KIAA0280, TCRP1
Chromosome Chromosome number
11
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
11q13.4
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT032061 hsa-miR-16-5p Sequencing 20371350
MIRT047685 hsa-miR-10a-5p CLASH 23622248
MIRT507347 hsa-miR-548e-5p PAR-CLIP 23446348
MIRT507346 hsa-miR-6888-5p PAR-CLIP 23446348
MIRT507345 hsa-miR-6808-5p PAR-CLIP 23446348
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 21516116, 23251525, 24722188, 25260657, 25416956, 26871637, 31515488, 32296183
GO:1905053 Process Positive regulation of base-excision repair IBA
GO:1905053 Process Positive regulation of base-excision repair IDA 25260657
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
616316 28999 ENSG00000054965
Protein
UniProt ID Q92567
Protein name Protein FAM168A (Tongue cancer chemotherapy resistance-associated protein 1)
Protein function In cancer context, protects cells from induced-DNA damage and apoptosis. Acts, at least in part, through PI3K/AKT/NFKB signaling pathway and by preventing POLB degradation. Decreases POLB ubiquitation and stabilizes its protein levels. {ECO:0000
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF14944 TCRP1 1 244 Tongue Cancer Chemotherapy Resistant Protein 1 Family
Sequence
Sequence length 244
Interactions View interactions
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Schizophrenia Schizophrenia N/A N/A GWAS
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Lung Neoplasms Associate 28859669
Neoplasms Adipose Tissue Associate 34872092
Squamous Cell Carcinoma of Head and Neck Associate 21334329, 23251525