FAM168A (family with sequence similarity 168 member A)

Gene

• Entrez ID: 23201
• Gene name: Family with sequence similarity 168 member A
• Gene symbol: FAM168A
• Synonyms (NCBI Gene): KIAA0280, TCRP1
• Chromosome: 11
• Chromosome location: 11q13.4

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT032061	hsa-miR-16-5p	Sequencing	20371350
MIRT047685	hsa-miR-10a-5p	CLASH	23622248
MIRT507347	hsa-miR-548e-5p	PAR-CLIP	23446348
MIRT507346	hsa-miR-6888-5p	PAR-CLIP	23446348
MIRT507345	hsa-miR-6808-5p	PAR-CLIP	23446348
MIRT507344	hsa-miR-6893-5p	PAR-CLIP	23446348
MIRT507343	hsa-miR-940	PAR-CLIP	23446348
MIRT507342	hsa-miR-4259	PAR-CLIP	23446348
MIRT507341	hsa-miR-4768-3p	PAR-CLIP	23446348
MIRT507340	hsa-miR-1827	PAR-CLIP	23446348
MIRT507338	hsa-miR-4722-5p	PAR-CLIP	23446348
MIRT507339	hsa-miR-6731-5p	PAR-CLIP	23446348
MIRT507337	hsa-miR-8085	PAR-CLIP	23446348
MIRT507336	hsa-miR-3175	PAR-CLIP	23446348
MIRT507335	hsa-miR-1343-5p	PAR-CLIP	23446348
MIRT507334	hsa-miR-939-5p	PAR-CLIP	23446348
MIRT507333	hsa-miR-6825-5p	PAR-CLIP	23446348
MIRT507332	hsa-miR-2110	PAR-CLIP	23446348
MIRT507331	hsa-miR-6810-5p	PAR-CLIP	23446348
MIRT507330	hsa-miR-3150a-3p	PAR-CLIP	23446348
MIRT507329	hsa-miR-6763-5p	PAR-CLIP	23446348
MIRT507328	hsa-miR-6857-5p	PAR-CLIP	23446348
MIRT507327	hsa-miR-450a-2-3p	PAR-CLIP	23446348
MIRT477094	hsa-miR-4476	PAR-CLIP	23592263
MIRT477093	hsa-miR-6876-5p	PAR-CLIP	23592263
MIRT477092	hsa-miR-4695-5p	PAR-CLIP	23592263
MIRT477091	hsa-miR-4779	PAR-CLIP	23592263
MIRT477090	hsa-miR-3179	PAR-CLIP	23592263
MIRT477089	hsa-miR-3202	PAR-CLIP	23592263
MIRT477088	hsa-miR-766-5p	PAR-CLIP	23592263
MIRT477086	hsa-miR-6801-5p	PAR-CLIP	23592263
MIRT477087	hsa-miR-4266	PAR-CLIP	23592263
MIRT448196	hsa-miR-4428	PAR-CLIP	22100165
MIRT448195	hsa-miR-3173-3p	PAR-CLIP	22100165
MIRT448194	hsa-miR-6891-5p	PAR-CLIP	22100165
MIRT448193	hsa-miR-28-5p	PAR-CLIP	22100165
MIRT448191	hsa-miR-3139	PAR-CLIP	22100165
MIRT448192	hsa-miR-708-5p	PAR-CLIP	22100165
MIRT448190	hsa-miR-331-3p	PAR-CLIP	22100165
MIRT448189	hsa-miR-4292	PAR-CLIP	22100165
MIRT448188	hsa-miR-6791-5p	PAR-CLIP	22100165
MIRT448187	hsa-miR-6742-3p	PAR-CLIP	22100165
MIRT448186	hsa-miR-6861-5p	PAR-CLIP	22100165
MIRT448185	hsa-miR-5702	PAR-CLIP	22100165
MIRT448184	hsa-miR-765	PAR-CLIP	22100165
MIRT448183	hsa-miR-555	PAR-CLIP	22100165
MIRT448182	hsa-miR-937-5p	PAR-CLIP	22100165
MIRT448181	hsa-miR-627-5p	PAR-CLIP	22100165
MIRT448180	hsa-miR-8081	PAR-CLIP	22100165
MIRT507347	hsa-miR-548e-5p	PAR-CLIP	23446348
MIRT507346	hsa-miR-6888-5p	PAR-CLIP	23446348
MIRT507345	hsa-miR-6808-5p	PAR-CLIP	23446348
MIRT507344	hsa-miR-6893-5p	PAR-CLIP	23446348
MIRT507343	hsa-miR-940	PAR-CLIP	23446348
MIRT507342	hsa-miR-4259	PAR-CLIP	23446348
MIRT507341	hsa-miR-4768-3p	PAR-CLIP	23446348
MIRT507340	hsa-miR-1827	PAR-CLIP	23446348
MIRT507338	hsa-miR-4722-5p	PAR-CLIP	23446348
MIRT507339	hsa-miR-6731-5p	PAR-CLIP	23446348
MIRT507337	hsa-miR-8085	PAR-CLIP	23446348
MIRT507336	hsa-miR-3175	PAR-CLIP	23446348
MIRT507335	hsa-miR-1343-5p	PAR-CLIP	23446348
MIRT507334	hsa-miR-939-5p	PAR-CLIP	23446348
MIRT507333	hsa-miR-6825-5p	PAR-CLIP	23446348
MIRT507332	hsa-miR-2110	PAR-CLIP	23446348
MIRT507331	hsa-miR-6810-5p	PAR-CLIP	23446348
MIRT507330	hsa-miR-3150a-3p	PAR-CLIP	23446348
MIRT507329	hsa-miR-6763-5p	PAR-CLIP	23446348
MIRT507328	hsa-miR-6857-5p	PAR-CLIP	23446348
MIRT507327	hsa-miR-450a-2-3p	PAR-CLIP	23446348
MIRT477094	hsa-miR-4476	PAR-CLIP	23592263
MIRT477093	hsa-miR-6876-5p	PAR-CLIP	23592263
MIRT477092	hsa-miR-4695-5p	PAR-CLIP	23592263
MIRT477091	hsa-miR-4779	PAR-CLIP	23592263
MIRT477090	hsa-miR-3179	PAR-CLIP	23592263
MIRT477089	hsa-miR-3202	PAR-CLIP	23592263
MIRT477088	hsa-miR-766-5p	PAR-CLIP	23592263
MIRT477086	hsa-miR-6801-5p	PAR-CLIP	23592263
MIRT477087	hsa-miR-4266	PAR-CLIP	23592263
MIRT448196	hsa-miR-4428	PAR-CLIP	22100165
MIRT448195	hsa-miR-3173-3p	PAR-CLIP	22100165
MIRT448194	hsa-miR-6891-5p	PAR-CLIP	22100165
MIRT448193	hsa-miR-28-5p	PAR-CLIP	22100165
MIRT448191	hsa-miR-3139	PAR-CLIP	22100165
MIRT448192	hsa-miR-708-5p	PAR-CLIP	22100165
MIRT448190	hsa-miR-331-3p	PAR-CLIP	22100165
MIRT448189	hsa-miR-4292	PAR-CLIP	22100165
MIRT448188	hsa-miR-6791-5p	PAR-CLIP	22100165
MIRT448187	hsa-miR-6742-3p	PAR-CLIP	22100165
MIRT448186	hsa-miR-6861-5p	PAR-CLIP	22100165
MIRT448185	hsa-miR-5702	PAR-CLIP	22100165
MIRT448184	hsa-miR-765	PAR-CLIP	22100165
MIRT448183	hsa-miR-555	PAR-CLIP	22100165
MIRT448182	hsa-miR-937-5p	PAR-CLIP	22100165
MIRT448181	hsa-miR-627-5p	PAR-CLIP	22100165
MIRT448180	hsa-miR-8081	PAR-CLIP	22100165
MIRT981654	hsa-miR-1193	CLIP-seq
MIRT981655	hsa-miR-1197	CLIP-seq
MIRT981656	hsa-miR-1205	CLIP-seq
MIRT981657	hsa-miR-1587	CLIP-seq
MIRT981658	hsa-miR-1915	CLIP-seq
MIRT981659	hsa-miR-2355-5p	CLIP-seq
MIRT981660	hsa-miR-3162-5p	CLIP-seq
MIRT981661	hsa-miR-4436a	CLIP-seq
MIRT981662	hsa-miR-4492	CLIP-seq
MIRT981663	hsa-miR-4498	CLIP-seq
MIRT981664	hsa-miR-4656	CLIP-seq
MIRT981665	hsa-miR-4675	CLIP-seq
MIRT981666	hsa-miR-4700-3p	CLIP-seq
MIRT981667	hsa-miR-4741	CLIP-seq
MIRT981668	hsa-miR-762	CLIP-seq
MIRT981655	hsa-miR-1197	CLIP-seq
MIRT1990829	hsa-miR-1236	CLIP-seq
MIRT1990830	hsa-miR-1244	CLIP-seq
MIRT1990831	hsa-miR-1468	CLIP-seq
MIRT981658	hsa-miR-1915	CLIP-seq
MIRT1990832	hsa-miR-2278	CLIP-seq
MIRT981659	hsa-miR-2355-5p	CLIP-seq
MIRT1990833	hsa-miR-3065-3p	CLIP-seq
MIRT1990834	hsa-miR-3121-3p	CLIP-seq
MIRT981660	hsa-miR-3162-5p	CLIP-seq
MIRT1990835	hsa-miR-338-3p	CLIP-seq
MIRT1990836	hsa-miR-3907	CLIP-seq
MIRT1990837	hsa-miR-3918	CLIP-seq
MIRT1990838	hsa-miR-4325	CLIP-seq
MIRT1990839	hsa-miR-4432	CLIP-seq
MIRT981661	hsa-miR-4436a	CLIP-seq
MIRT1990840	hsa-miR-4468	CLIP-seq
MIRT1990841	hsa-miR-4471	CLIP-seq
MIRT1990842	hsa-miR-4530	CLIP-seq
MIRT1990843	hsa-miR-4640-5p	CLIP-seq
MIRT1990844	hsa-miR-4685-5p	CLIP-seq
MIRT981666	hsa-miR-4700-3p	CLIP-seq
MIRT1990845	hsa-miR-4725-5p	CLIP-seq
MIRT1990846	hsa-miR-4726-5p	CLIP-seq
MIRT1990847	hsa-miR-4778-3p	CLIP-seq
MIRT1990848	hsa-miR-493	CLIP-seq
MIRT1990849	hsa-miR-499-5p	CLIP-seq
MIRT1990850	hsa-miR-504	CLIP-seq
MIRT1990851	hsa-miR-518a-5p	CLIP-seq
MIRT1990852	hsa-miR-520d-5p	CLIP-seq
MIRT1990853	hsa-miR-524-5p	CLIP-seq
MIRT1990854	hsa-miR-527	CLIP-seq
MIRT1990855	hsa-miR-593	CLIP-seq
MIRT1990856	hsa-miR-646	CLIP-seq
MIRT1990857	hsa-miR-766	CLIP-seq
MIRT981655	hsa-miR-1197	CLIP-seq
MIRT2225042	hsa-miR-1207-5p	CLIP-seq
MIRT1990829	hsa-miR-1236	CLIP-seq
MIRT1990831	hsa-miR-1468	CLIP-seq
MIRT2225043	hsa-miR-1909	CLIP-seq
MIRT981658	hsa-miR-1915	CLIP-seq
MIRT981659	hsa-miR-2355-5p	CLIP-seq
MIRT1990834	hsa-miR-3121-3p	CLIP-seq
MIRT981660	hsa-miR-3162-5p	CLIP-seq
MIRT2225044	hsa-miR-3187-3p	CLIP-seq
MIRT1990836	hsa-miR-3907	CLIP-seq
MIRT1990837	hsa-miR-3918	CLIP-seq
MIRT1990838	hsa-miR-4325	CLIP-seq
MIRT2225045	hsa-miR-4435	CLIP-seq
MIRT981661	hsa-miR-4436a	CLIP-seq
MIRT2225046	hsa-miR-4436b-3p	CLIP-seq
MIRT1990841	hsa-miR-4471	CLIP-seq
MIRT2225047	hsa-miR-4487	CLIP-seq
MIRT2225048	hsa-miR-4489	CLIP-seq
MIRT2225049	hsa-miR-4533	CLIP-seq
MIRT1990843	hsa-miR-4640-5p	CLIP-seq
MIRT1990844	hsa-miR-4685-5p	CLIP-seq
MIRT981666	hsa-miR-4700-3p	CLIP-seq
MIRT2225050	hsa-miR-4701-5p	CLIP-seq
MIRT2225051	hsa-miR-4716-3p	CLIP-seq
MIRT1990845	hsa-miR-4725-5p	CLIP-seq
MIRT1990846	hsa-miR-4726-5p	CLIP-seq
MIRT2225052	hsa-miR-4763-3p	CLIP-seq
MIRT1990847	hsa-miR-4778-3p	CLIP-seq
MIRT1990848	hsa-miR-493	CLIP-seq
MIRT1990850	hsa-miR-504	CLIP-seq
MIRT1990851	hsa-miR-518a-5p	CLIP-seq
MIRT1990854	hsa-miR-527	CLIP-seq
MIRT2225053	hsa-miR-548s	CLIP-seq
MIRT2225054	hsa-miR-588	CLIP-seq
MIRT1990855	hsa-miR-593	CLIP-seq
MIRT2225055	hsa-miR-607	CLIP-seq
MIRT2225056	hsa-miR-769-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	21516116, 23251525, 24722188, 25260657, 25416956, 26871637, 31515488, 32296183
GO:1905053	Process	Positive regulation of base-excision repair	IBA
GO:1905053	Process	Positive regulation of base-excision repair	IDA	25260657

Other IDs

• MIM: 616316
• HGNC: 28999
• e!Ensembl: ENSG00000054965

Protein

• UniProt ID: Q92567
• Protein name: Protein FAM168A (Tongue cancer chemotherapy resistance-associated protein 1)
• Protein function: In cancer context, protects cells from induced-DNA damage and apoptosis. Acts, at least in part, through PI3K/AKT/NFKB signaling pathway and by preventing POLB degradation. Decreases POLB ubiquitation and stabilizes its protein levels. {ECO:0000
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF14944	TCRP1	1 → 244	Tongue Cancer Chemotherapy Resistant Protein 1	Family

• Sequence:

  MNPVYSPVQPGAPYGNPKNMAYTGYPTAYPAAAPAYNPSLYPTNSPSYAPEFQFLHSAYA
  TLLMKQAWPQNSSSCGTEGTFHLPVDTGTENRTYQASSAAFRYTAGTPYKVPPTQSNTAP
  PPYSPSPNPYQTAMYPIRSAYPQQNLYAQGAYYTQPVYAAQPHVIHHTTVVQPNSIPSAI
  YPAPVAAPRTNGVAMGMVAGTTMAMSAGTLLTTPQHTAIGAHPVSMPTYRAQGTPAYSYV
  PPHW

• Sequence length: 244