MPRIP (myosin phosphatase Rho interacting protein)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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23164 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Myosin phosphatase Rho interacting protein |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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MPRIP |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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M-RIP, MRIP, RHOIP3, RIP3, p116Rip |
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Chromosome
Chromosome number
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17 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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17p11.2 |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||
| UniProt ID | Q6WCQ1 | |||||||||||||||
| Protein name | Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip) | |||||||||||||||
| Protein function | Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers b | |||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 1025 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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