Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	23162
Gene name Gene Name - the full gene name approved by the HGNC.	Mitogen-activated protein kinase 8 interacting protein 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	MAPK8IP3
Synonyms (NCBI Gene) Gene synonyms aliases	JIP-3, JIP3, JSAP1, NEDBA, SYD2, syd
Disease Acronyms (UniProt) Disease acronyms from UniProt database	NEDBA
Chromosome Chromosome number	16
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	16p13.3
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and reg

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SNP ID	Visualize variation	Clinical significance	Consequence
rs770703007	C>G,T	Likely-pathogenic	Genic upstream transcript variant, synonymous variant, stop gained, non coding transcript variant, coding sequence variant, 5 prime UTR variant
rs1479142047	G>C,T	Likely-pathogenic	Coding sequence variant, non coding transcript variant, missense variant, genic upstream transcript variant, 5 prime UTR variant, stop gained
rs1567128142	G>-	Pathogenic	Frameshift variant, coding sequence variant, non coding transcript variant, genic upstream transcript variant, 5 prime UTR variant
rs1567198751	T>C	Likely-pathogenic	Missense variant, non coding transcript variant, coding sequence variant
rs1567203083	C>T	Pathogenic-likely-pathogenic	Missense variant, non coding transcript variant, coding sequence variant
rs1567214097	C>T	Likely-pathogenic	Missense variant, genic downstream transcript variant, coding sequence variant

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miRTarBase ID	miRNA	Experiments	Reference
MIRT044821	hsa-miR-320a	CLASH	23622248
MIRT711827	hsa-miR-3127-3p	HITS-CLIP	19536157
MIRT711826	hsa-miR-6756-3p	HITS-CLIP	19536157
MIRT711825	hsa-miR-5088-3p	HITS-CLIP	19536157
MIRT711824	hsa-miR-1248	HITS-CLIP	19536157
MIRT711823	hsa-miR-4778-3p	HITS-CLIP	19536157
MIRT711822	hsa-miR-6778-3p	HITS-CLIP	19536157
MIRT724681	hsa-miR-378a-5p	HITS-CLIP	19536157
MIRT724680	hsa-miR-1200	HITS-CLIP	19536157
MIRT711821	hsa-miR-6875-3p	HITS-CLIP	19536157
MIRT711827	hsa-miR-3127-3p	HITS-CLIP	19536157
MIRT711826	hsa-miR-6756-3p	HITS-CLIP	19536157
MIRT711825	hsa-miR-5088-3p	HITS-CLIP	19536157
MIRT711824	hsa-miR-1248	HITS-CLIP	19536157
MIRT711823	hsa-miR-4778-3p	HITS-CLIP	19536157
MIRT711822	hsa-miR-6778-3p	HITS-CLIP	19536157
MIRT711821	hsa-miR-6875-3p	HITS-CLIP	19536157
MIRT375251	hsa-miR-5197-3p	PAR-CLIP	20371350
MIRT500211	hsa-miR-3064-5p	PAR-CLIP	20371350
MIRT500210	hsa-miR-6504-5p	PAR-CLIP	20371350
MIRT500209	hsa-miR-3184-5p	PAR-CLIP	20371350
MIRT500208	hsa-miR-423-5p	PAR-CLIP	20371350
MIRT500207	hsa-miR-6720-3p	PAR-CLIP	20371350
MIRT500206	hsa-miR-3960	PAR-CLIP	20371350
MIRT500205	hsa-miR-8072	PAR-CLIP	20371350
MIRT500203	hsa-miR-566	PAR-CLIP	20371350
MIRT500202	hsa-miR-4467	PAR-CLIP	20371350
MIRT500201	hsa-miR-3652	PAR-CLIP	20371350
MIRT500200	hsa-miR-4430	PAR-CLIP	20371350
MIRT500198	hsa-miR-4505	PAR-CLIP	20371350
MIRT500199	hsa-miR-5787	PAR-CLIP	20371350
MIRT500197	hsa-miR-3180	PAR-CLIP	20371350
MIRT500196	hsa-miR-3180-3p	PAR-CLIP	20371350
MIRT500195	hsa-miR-3196	PAR-CLIP	20371350
MIRT500194	hsa-miR-6816-5p	PAR-CLIP	20371350
MIRT500193	hsa-miR-6842-3p	PAR-CLIP	20371350
MIRT375251	hsa-miR-5197-3p	PAR-CLIP	20371350
MIRT500211	hsa-miR-3064-5p	PAR-CLIP	20371350
MIRT500210	hsa-miR-6504-5p	PAR-CLIP	20371350
MIRT500209	hsa-miR-3184-5p	PAR-CLIP	20371350
MIRT500208	hsa-miR-423-5p	PAR-CLIP	20371350
MIRT500207	hsa-miR-6720-3p	PAR-CLIP	20371350
MIRT500206	hsa-miR-3960	PAR-CLIP	20371350
MIRT500205	hsa-miR-8072	PAR-CLIP	20371350
MIRT500204	hsa-miR-5580-5p	PAR-CLIP	20371350
MIRT500203	hsa-miR-566	PAR-CLIP	20371350
MIRT500202	hsa-miR-4467	PAR-CLIP	20371350
MIRT500201	hsa-miR-3652	PAR-CLIP	20371350
MIRT500200	hsa-miR-4430	PAR-CLIP	20371350
MIRT500198	hsa-miR-4505	PAR-CLIP	20371350
MIRT500199	hsa-miR-5787	PAR-CLIP	20371350
MIRT500197	hsa-miR-3180	PAR-CLIP	20371350
MIRT500196	hsa-miR-3180-3p	PAR-CLIP	20371350
MIRT500195	hsa-miR-3196	PAR-CLIP	20371350
MIRT500194	hsa-miR-6816-5p	PAR-CLIP	20371350
MIRT500193	hsa-miR-6842-3p	PAR-CLIP	20371350
MIRT375251	hsa-miR-5197-3p	PAR-CLIP	24398324
MIRT500211	hsa-miR-3064-5p	PAR-CLIP	24398324
MIRT500210	hsa-miR-6504-5p	PAR-CLIP	24398324
MIRT500209	hsa-miR-3184-5p	PAR-CLIP	24398324
MIRT500208	hsa-miR-423-5p	PAR-CLIP	24398324
MIRT500207	hsa-miR-6720-3p	PAR-CLIP	24398324
MIRT500206	hsa-miR-3960	PAR-CLIP	24398324
MIRT500205	hsa-miR-8072	PAR-CLIP	24398324
MIRT500204	hsa-miR-5580-5p	PAR-CLIP	24398324
MIRT500203	hsa-miR-566	PAR-CLIP	24398324
MIRT500202	hsa-miR-4467	PAR-CLIP	24398324
MIRT500201	hsa-miR-3652	PAR-CLIP	24398324
MIRT500200	hsa-miR-4430	PAR-CLIP	24398324
MIRT500198	hsa-miR-4505	PAR-CLIP	24398324
MIRT500199	hsa-miR-5787	PAR-CLIP	24398324
MIRT500197	hsa-miR-3180	PAR-CLIP	24398324
MIRT500196	hsa-miR-3180-3p	PAR-CLIP	24398324
MIRT500195	hsa-miR-3196	PAR-CLIP	24398324
MIRT500194	hsa-miR-6816-5p	PAR-CLIP	24398324
MIRT500193	hsa-miR-6842-3p	PAR-CLIP	24398324
MIRT500211	hsa-miR-3064-5p	PAR-CLIP	26701625
MIRT500196	hsa-miR-3180-3p	PAR-CLIP	26701625
MIRT500197	hsa-miR-3180	PAR-CLIP	26701625
MIRT500209	hsa-miR-3184-5p	PAR-CLIP	26701625
MIRT500195	hsa-miR-3196	PAR-CLIP	26701625
MIRT500201	hsa-miR-3652	PAR-CLIP	26701625
MIRT500206	hsa-miR-3960	PAR-CLIP	26701625
MIRT500208	hsa-miR-423-5p	PAR-CLIP	26701625
MIRT500200	hsa-miR-4430	PAR-CLIP	26701625
MIRT500202	hsa-miR-4467	PAR-CLIP	26701625
MIRT500198	hsa-miR-4505	PAR-CLIP	26701625
MIRT375251	hsa-miR-5197-3p	PAR-CLIP	26701625
MIRT500203	hsa-miR-566	PAR-CLIP	26701625
MIRT500199	hsa-miR-5787	PAR-CLIP	26701625
MIRT500210	hsa-miR-6504-5p	PAR-CLIP	26701625
MIRT500207	hsa-miR-6720-3p	PAR-CLIP	26701625
MIRT500194	hsa-miR-6816-5p	PAR-CLIP	26701625
MIRT500193	hsa-miR-6842-3p	PAR-CLIP	26701625
MIRT500205	hsa-miR-8072	PAR-CLIP	26701625
MIRT711827	hsa-miR-3127-3p	HITS-CLIP	19536157
MIRT711826	hsa-miR-6756-3p	HITS-CLIP	19536157
MIRT711825	hsa-miR-5088-3p	HITS-CLIP	19536157
MIRT711824	hsa-miR-1248	HITS-CLIP	19536157
MIRT711823	hsa-miR-4778-3p	HITS-CLIP	19536157
MIRT711822	hsa-miR-6778-3p	HITS-CLIP	19536157
MIRT724681	hsa-miR-378a-5p	HITS-CLIP	19536157
MIRT724680	hsa-miR-1200	HITS-CLIP	19536157
MIRT711821	hsa-miR-6875-3p	HITS-CLIP	19536157
MIRT711827	hsa-miR-3127-3p	HITS-CLIP	19536157
MIRT711826	hsa-miR-6756-3p	HITS-CLIP	19536157
MIRT711825	hsa-miR-5088-3p	HITS-CLIP	19536157
MIRT711824	hsa-miR-1248	HITS-CLIP	19536157
MIRT711823	hsa-miR-4778-3p	HITS-CLIP	19536157
MIRT711822	hsa-miR-6778-3p	HITS-CLIP	19536157
MIRT711821	hsa-miR-6875-3p	HITS-CLIP	19536157
MIRT375251	hsa-miR-5197-3p	PAR-CLIP	20371350
MIRT500211	hsa-miR-3064-5p	PAR-CLIP	20371350
MIRT500210	hsa-miR-6504-5p	PAR-CLIP	20371350
MIRT500209	hsa-miR-3184-5p	PAR-CLIP	20371350
MIRT500208	hsa-miR-423-5p	PAR-CLIP	20371350
MIRT500207	hsa-miR-6720-3p	PAR-CLIP	20371350
MIRT500206	hsa-miR-3960	PAR-CLIP	20371350
MIRT500205	hsa-miR-8072	PAR-CLIP	20371350
MIRT500203	hsa-miR-566	PAR-CLIP	20371350
MIRT500202	hsa-miR-4467	PAR-CLIP	20371350
MIRT500201	hsa-miR-3652	PAR-CLIP	20371350
MIRT500200	hsa-miR-4430	PAR-CLIP	20371350
MIRT500198	hsa-miR-4505	PAR-CLIP	20371350
MIRT500199	hsa-miR-5787	PAR-CLIP	20371350
MIRT500197	hsa-miR-3180	PAR-CLIP	20371350
MIRT500196	hsa-miR-3180-3p	PAR-CLIP	20371350
MIRT500195	hsa-miR-3196	PAR-CLIP	20371350
MIRT500194	hsa-miR-6816-5p	PAR-CLIP	20371350
MIRT500193	hsa-miR-6842-3p	PAR-CLIP	20371350
MIRT375251	hsa-miR-5197-3p	PAR-CLIP	20371350
MIRT500211	hsa-miR-3064-5p	PAR-CLIP	20371350
MIRT500210	hsa-miR-6504-5p	PAR-CLIP	20371350
MIRT500209	hsa-miR-3184-5p	PAR-CLIP	20371350
MIRT500208	hsa-miR-423-5p	PAR-CLIP	20371350
MIRT500207	hsa-miR-6720-3p	PAR-CLIP	20371350
MIRT500206	hsa-miR-3960	PAR-CLIP	20371350
MIRT500205	hsa-miR-8072	PAR-CLIP	20371350
MIRT500204	hsa-miR-5580-5p	PAR-CLIP	20371350
MIRT500203	hsa-miR-566	PAR-CLIP	20371350
MIRT500202	hsa-miR-4467	PAR-CLIP	20371350
MIRT500201	hsa-miR-3652	PAR-CLIP	20371350
MIRT500200	hsa-miR-4430	PAR-CLIP	20371350
MIRT500198	hsa-miR-4505	PAR-CLIP	20371350
MIRT500199	hsa-miR-5787	PAR-CLIP	20371350
MIRT500197	hsa-miR-3180	PAR-CLIP	20371350
MIRT500196	hsa-miR-3180-3p	PAR-CLIP	20371350
MIRT500195	hsa-miR-3196	PAR-CLIP	20371350
MIRT500194	hsa-miR-6816-5p	PAR-CLIP	20371350
MIRT500193	hsa-miR-6842-3p	PAR-CLIP	20371350
MIRT375251	hsa-miR-5197-3p	PAR-CLIP	24398324
MIRT500211	hsa-miR-3064-5p	PAR-CLIP	24398324
MIRT500210	hsa-miR-6504-5p	PAR-CLIP	24398324
MIRT500209	hsa-miR-3184-5p	PAR-CLIP	24398324
MIRT500208	hsa-miR-423-5p	PAR-CLIP	24398324
MIRT500207	hsa-miR-6720-3p	PAR-CLIP	24398324
MIRT500206	hsa-miR-3960	PAR-CLIP	24398324
MIRT500205	hsa-miR-8072	PAR-CLIP	24398324
MIRT500204	hsa-miR-5580-5p	PAR-CLIP	24398324
MIRT500203	hsa-miR-566	PAR-CLIP	24398324
MIRT500202	hsa-miR-4467	PAR-CLIP	24398324
MIRT500201	hsa-miR-3652	PAR-CLIP	24398324
MIRT500200	hsa-miR-4430	PAR-CLIP	24398324
MIRT500198	hsa-miR-4505	PAR-CLIP	24398324
MIRT500199	hsa-miR-5787	PAR-CLIP	24398324
MIRT500197	hsa-miR-3180	PAR-CLIP	24398324
MIRT500196	hsa-miR-3180-3p	PAR-CLIP	24398324
MIRT500195	hsa-miR-3196	PAR-CLIP	24398324
MIRT500194	hsa-miR-6816-5p	PAR-CLIP	24398324
MIRT500193	hsa-miR-6842-3p	PAR-CLIP	24398324
MIRT1131171	hsa-miR-1207-5p	CLIP-seq
MIRT1131172	hsa-miR-1224-3p	CLIP-seq
MIRT1131173	hsa-miR-1260	CLIP-seq
MIRT1131174	hsa-miR-1260b	CLIP-seq
MIRT1131175	hsa-miR-1273e	CLIP-seq
MIRT1131176	hsa-miR-1275	CLIP-seq
MIRT1131177	hsa-miR-1280	CLIP-seq
MIRT1131178	hsa-miR-1324	CLIP-seq
MIRT1131179	hsa-miR-1343	CLIP-seq
MIRT1131180	hsa-miR-146b-3p	CLIP-seq
MIRT1131181	hsa-miR-1827	CLIP-seq
MIRT1131182	hsa-miR-1908	CLIP-seq
MIRT1131183	hsa-miR-1909	CLIP-seq
MIRT1131184	hsa-miR-208a	CLIP-seq
MIRT1131185	hsa-miR-208b	CLIP-seq
MIRT1131186	hsa-miR-22	CLIP-seq
MIRT1131187	hsa-miR-2392	CLIP-seq
MIRT1131188	hsa-miR-2467-5p	CLIP-seq
MIRT1131189	hsa-miR-28-5p	CLIP-seq
MIRT1131190	hsa-miR-3126-5p	CLIP-seq
MIRT1131191	hsa-miR-3139	CLIP-seq
MIRT1131192	hsa-miR-3173-5p	CLIP-seq
MIRT1131193	hsa-miR-3188	CLIP-seq
MIRT1131194	hsa-miR-3189-5p	CLIP-seq
MIRT1131195	hsa-miR-3192	CLIP-seq
MIRT1131196	hsa-miR-320e	CLIP-seq
MIRT1131197	hsa-miR-3612	CLIP-seq
MIRT1131198	hsa-miR-3616-3p	CLIP-seq
MIRT1131199	hsa-miR-3617	CLIP-seq
MIRT1131200	hsa-miR-3620	CLIP-seq
MIRT1131201	hsa-miR-3689a-3p	CLIP-seq
MIRT1131202	hsa-miR-3689c	CLIP-seq
MIRT1131203	hsa-miR-3918	CLIP-seq
MIRT1131204	hsa-miR-3926	CLIP-seq
MIRT1131205	hsa-miR-3929	CLIP-seq
MIRT1131206	hsa-miR-3975	CLIP-seq
MIRT1131207	hsa-miR-4251	CLIP-seq
MIRT1131208	hsa-miR-4274	CLIP-seq
MIRT1131209	hsa-miR-4292	CLIP-seq
MIRT1131210	hsa-miR-4293	CLIP-seq
MIRT1131211	hsa-miR-4314	CLIP-seq
MIRT1131212	hsa-miR-4324	CLIP-seq
MIRT1131213	hsa-miR-4327	CLIP-seq
MIRT1131214	hsa-miR-4419b	CLIP-seq
MIRT1131215	hsa-miR-4433	CLIP-seq
MIRT1131216	hsa-miR-4435	CLIP-seq
MIRT1131217	hsa-miR-4459	CLIP-seq
MIRT1131218	hsa-miR-4478	CLIP-seq
MIRT1131219	hsa-miR-4488	CLIP-seq
MIRT1131220	hsa-miR-4512	CLIP-seq
MIRT1131221	hsa-miR-4519	CLIP-seq
MIRT1131222	hsa-miR-4525	CLIP-seq
MIRT1131223	hsa-miR-4646-5p	CLIP-seq
MIRT1131224	hsa-miR-4649-3p	CLIP-seq
MIRT1131225	hsa-miR-4663	CLIP-seq
MIRT1131226	hsa-miR-4665-5p	CLIP-seq
MIRT1131227	hsa-miR-4685-5p	CLIP-seq
MIRT1131228	hsa-miR-4691-5p	CLIP-seq
MIRT1131229	hsa-miR-4695-5p	CLIP-seq
MIRT1131230	hsa-miR-4697-5p	CLIP-seq
MIRT1131231	hsa-miR-4700-3p	CLIP-seq
MIRT1131232	hsa-miR-4714-3p	CLIP-seq
MIRT1131233	hsa-miR-4721	CLIP-seq
MIRT1131234	hsa-miR-4723-5p	CLIP-seq
MIRT1131235	hsa-miR-4728-5p	CLIP-seq
MIRT1131236	hsa-miR-4729	CLIP-seq
MIRT1131237	hsa-miR-4761-5p	CLIP-seq
MIRT1131238	hsa-miR-4763-3p	CLIP-seq
MIRT1131239	hsa-miR-4763-5p	CLIP-seq
MIRT1131240	hsa-miR-4787-5p	CLIP-seq
MIRT1131241	hsa-miR-483-3p	CLIP-seq
MIRT1131242	hsa-miR-485-5p	CLIP-seq
MIRT1131243	hsa-miR-499-5p	CLIP-seq
MIRT1131244	hsa-miR-539	CLIP-seq
MIRT1131245	hsa-miR-544b	CLIP-seq
MIRT1131246	hsa-miR-558	CLIP-seq
MIRT1131247	hsa-miR-593	CLIP-seq
MIRT1131248	hsa-miR-605	CLIP-seq
MIRT1131249	hsa-miR-625	CLIP-seq
MIRT1131250	hsa-miR-629	CLIP-seq
MIRT1131251	hsa-miR-637	CLIP-seq
MIRT1131252	hsa-miR-641	CLIP-seq
MIRT1131253	hsa-miR-650	CLIP-seq
MIRT1131254	hsa-miR-663	CLIP-seq
MIRT1131255	hsa-miR-663b	CLIP-seq
MIRT1131256	hsa-miR-665	CLIP-seq
MIRT1131257	hsa-miR-671-5p	CLIP-seq
MIRT1131258	hsa-miR-708	CLIP-seq
MIRT1131259	hsa-miR-759	CLIP-seq
MIRT1131260	hsa-miR-874	CLIP-seq
MIRT1131261	hsa-miR-885-3p	CLIP-seq
MIRT1131262	hsa-miR-940	CLIP-seq
MIRT1131171	hsa-miR-1207-5p	CLIP-seq
MIRT1131181	hsa-miR-1827	CLIP-seq
MIRT1131197	hsa-miR-3612	CLIP-seq
MIRT1131217	hsa-miR-4459	CLIP-seq
MIRT1131227	hsa-miR-4685-5p	CLIP-seq
MIRT1131229	hsa-miR-4695-5p	CLIP-seq
MIRT1131238	hsa-miR-4763-3p	CLIP-seq
MIRT1131253	hsa-miR-650	CLIP-seq
MIRT1131262	hsa-miR-940	CLIP-seq
MIRT2267285	hsa-miR-1207-3p	CLIP-seq
MIRT1131171	hsa-miR-1207-5p	CLIP-seq
MIRT2267286	hsa-miR-1285	CLIP-seq
MIRT1131178	hsa-miR-1324	CLIP-seq
MIRT2267287	hsa-miR-2278	CLIP-seq
MIRT2267288	hsa-miR-3144-5p	CLIP-seq
MIRT2267289	hsa-miR-3187-5p	CLIP-seq
MIRT2267290	hsa-miR-3191	CLIP-seq
MIRT2267291	hsa-miR-342-5p	CLIP-seq
MIRT2267292	hsa-miR-4270	CLIP-seq
MIRT2267293	hsa-miR-4441	CLIP-seq
MIRT2267294	hsa-miR-4651	CLIP-seq
MIRT2267295	hsa-miR-4652-5p	CLIP-seq
MIRT2267296	hsa-miR-4664-5p	CLIP-seq
MIRT2267297	hsa-miR-4731-5p	CLIP-seq
MIRT1131238	hsa-miR-4763-3p	CLIP-seq
MIRT2267298	hsa-miR-491-5p	CLIP-seq
MIRT2267299	hsa-miR-608	CLIP-seq
MIRT2267300	hsa-miR-612	CLIP-seq
MIRT1131251	hsa-miR-637	CLIP-seq
MIRT2267285	hsa-miR-1207-3p	CLIP-seq
MIRT1131183	hsa-miR-1909	CLIP-seq
MIRT2267288	hsa-miR-3144-5p	CLIP-seq
MIRT2267290	hsa-miR-3191	CLIP-seq
MIRT2267291	hsa-miR-342-5p	CLIP-seq
MIRT2267294	hsa-miR-4651	CLIP-seq
MIRT2267295	hsa-miR-4652-5p	CLIP-seq
MIRT2267296	hsa-miR-4664-5p	CLIP-seq
MIRT2267297	hsa-miR-4731-5p	CLIP-seq
MIRT2267298	hsa-miR-491-5p	CLIP-seq
MIRT2267299	hsa-miR-608	CLIP-seq
MIRT1131260	hsa-miR-874	CLIP-seq
MIRT2567031	hsa-miR-1224-5p	CLIP-seq
MIRT1131180	hsa-miR-146b-3p	CLIP-seq
MIRT2567032	hsa-miR-18a	CLIP-seq
MIRT2567033	hsa-miR-18b	CLIP-seq
MIRT2567034	hsa-miR-2682	CLIP-seq
MIRT2567035	hsa-miR-3136-3p	CLIP-seq
MIRT1131192	hsa-miR-3173-5p	CLIP-seq
MIRT2567036	hsa-miR-3690	CLIP-seq
MIRT2567037	hsa-miR-371-3p	CLIP-seq
MIRT2567038	hsa-miR-371b-3p	CLIP-seq
MIRT2567039	hsa-miR-378	CLIP-seq
MIRT2567040	hsa-miR-378b	CLIP-seq
MIRT2567041	hsa-miR-378c	CLIP-seq
MIRT2567042	hsa-miR-378d	CLIP-seq
MIRT2567043	hsa-miR-378e	CLIP-seq
MIRT2567044	hsa-miR-378f	CLIP-seq
MIRT2567045	hsa-miR-378h	CLIP-seq
MIRT2567046	hsa-miR-378i	CLIP-seq
MIRT2567047	hsa-miR-3915	CLIP-seq
MIRT2567048	hsa-miR-422a	CLIP-seq
MIRT2567049	hsa-miR-4267	CLIP-seq
MIRT2567050	hsa-miR-4308	CLIP-seq
MIRT2567051	hsa-miR-449c	CLIP-seq
MIRT2567052	hsa-miR-4522	CLIP-seq
MIRT2567053	hsa-miR-4689	CLIP-seq
MIRT2567054	hsa-miR-4735-3p	CLIP-seq
MIRT2567055	hsa-miR-4751	CLIP-seq
MIRT1131237	hsa-miR-4761-5p	CLIP-seq
MIRT2567056	hsa-miR-515-3p	CLIP-seq
MIRT2567057	hsa-miR-519e	CLIP-seq
MIRT2567058	hsa-miR-550a	CLIP-seq
MIRT2567059	hsa-miR-661	CLIP-seq
MIRT1131260	hsa-miR-874	CLIP-seq
MIRT1131262	hsa-miR-940	CLIP-seq
MIRT2684591	hsa-miR-1915	CLIP-seq
MIRT2684592	hsa-miR-2467-3p	CLIP-seq
MIRT2567034	hsa-miR-2682	CLIP-seq
MIRT2684593	hsa-miR-296-5p	CLIP-seq
MIRT2567035	hsa-miR-3136-3p	CLIP-seq
MIRT2684594	hsa-miR-3678-3p	CLIP-seq
MIRT2567037	hsa-miR-371-3p	CLIP-seq
MIRT2567038	hsa-miR-371b-3p	CLIP-seq
MIRT2684595	hsa-miR-4257	CLIP-seq
MIRT2567049	hsa-miR-4267	CLIP-seq
MIRT2684596	hsa-miR-4436b-3p	CLIP-seq
MIRT2567051	hsa-miR-449c	CLIP-seq
MIRT2684597	hsa-miR-4514	CLIP-seq
MIRT1131227	hsa-miR-4685-5p	CLIP-seq
MIRT2684598	hsa-miR-4692	CLIP-seq
MIRT2567056	hsa-miR-515-3p	CLIP-seq
MIRT2567057	hsa-miR-519e	CLIP-seq
MIRT2684599	hsa-miR-541	CLIP-seq
MIRT2567058	hsa-miR-550a	CLIP-seq
MIRT2684600	hsa-miR-654-5p	CLIP-seq
MIRT2567059	hsa-miR-661	CLIP-seq
MIRT1131262	hsa-miR-940	CLIP-seq

Show/Hide all(24)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	ISS
GO:0005078	Function	MAP-kinase scaffold activity	IBA	21873635
GO:0005078	Function	MAP-kinase scaffold activity	ISS
GO:0005515	Function	Protein binding	IPI	27107012, 32296183
GO:0005737	Component	Cytoplasm	IBA	21873635
GO:0007257	Process	Activation of JUN kinase activity	IBA	21873635
GO:0007257	Process	Activation of JUN kinase activity	ISS
GO:0008432	Function	JUN kinase binding	IBA	21873635
GO:0016192	Process	Vesicle-mediated transport	IBA	21873635
GO:0016192	Process	Vesicle-mediated transport	ISS
GO:0019894	Function	Kinesin binding	IBA	21873635
GO:0019894	Function	Kinesin binding	ISS
GO:0030159	Function	Signaling receptor complex adaptor activity	IBA	21873635
GO:0030424	Component	Axon	ISS
GO:0030425	Component	Dendrite	ISS
GO:0030426	Component	Growth cone	IEA
GO:0031103	Process	Axon regeneration	ISS
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0044297	Component	Cell body	ISS
GO:0046328	Process	Regulation of JNK cascade	ISS
GO:0048471	Component	Perinuclear region of cytoplasm	ISS
GO:0061564	Process	Axon development	ISS
GO:0099641	Process	Anterograde axonal protein transport	ISS
GO:1904115	Component	Axon cytoplasm	IEA

MIM	HGNC	e!Ensembl
605431	6884	ENSG00000138834

Protein

UniProt ID

Q9UPT6

Protein name

C-Jun-amino-terminal kinase-interacting protein 3 (JIP-3) (JNK-interacting protein 3) (JNK MAP kinase scaffold protein 3) (Mitogen-activated protein kinase 8-interacting protein 3)

Protein function

The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module (PubMed:12189133). May function as a regulator of ve

PDB

4PXJ , 8PR2 , 8PR3 , 8PR4 , 8PTK

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF09744	Jnk-SapK_ap_N	29 → 184	JNK_SAPK-associated protein-1	Family
PF16471	JIP_LZII	414 → 484	JNK-interacting protein leucine zipper II	Coiled-coil
PF19056	WD40_2	943 → 1174		Repeat

Sequence

MMEIQMDEGGGVVVYQDDYCSGSVMSERVSGLAGSIYREFERLIHCYDEEVVKELMPLVV
NVLENLDSVLSENQEHEVELELLREDNEQLLTQYEREKALRRQAEEKFIEFEDALEQEKK
ELQIQVEHYEFQTRQLELKAKNYADQISRLEERESEMKKEYNALHQRHTEMIQTYVEHIE
RSKMQQVGGNSQTESSLPGRRKERPTSLNVFPLADGTVRAQIGGKLVPAGDHWHLSDLGQ
LQSSSSYQCPQDEMSESGQSSAAATPSTTGTKSNTPTSSVPSAAVTPLNESLQPLGDYGV
GSKNSKRAREKRDSRNMEVQVTQEMRNVSIGMGSSDEWSDVQDIIDSTPELDMCPETRLD
RTGSSPTQGIVNKAFGINTDSLYHELSTAGSEVIGDVDEGADLLGEFSVRDDFFGMGKEV
GNLLLENSQLLETKNALNVVKNDLIAKVDQLSGEQEVLRGELEAAKQAKVKLENRIKELE
EELKRVKSEAIIARREPKEEAEDVSSYLCTESDKIPMAQRRRFTRVEMARVLMERNQYKE
RLMELQEAVRWTEMIRASREHPSVQEKKKSTIWQFFSRLFSSSSSPPPAKRPYPSVNIHY
KSPTTAGFSQRRNHAMCPISAGSRPLEFFPDDDCTSSARREQKREQYRQVREHVRNDDGR
LQACGWSLPAKYKQLSPNGGQEDTRMKNVPVPVYCRPLVEKDPTMKLWCAAGVNLSGWRP
NEDDAGNGVKPAPGRDPLTCDREGDGEPKSAHTSPEKKKAKELPEMDATSSRVWILTSTL
TTSKVVIIDANQPGTVVDQFTVCNAHVLCISSIPAASDSDYPPGEMFLDSDVNPEDPGAD
GVLAGITLVGCATRCNVPRSNCSSRGDTPVLDKGQGEVATIANGKVNPSQSTEEATEATE
VPDPGPSEPETATLRPGPLTEHVFTDPAPTPSSGPQPGSENGPEPDSSSTRPEPEPSGDP
TGAGSSAAPTMWLGAQNGWLYVHSAVANWKKCLHSIKLKDSVLSLVHVKGRVLVALADGT
LAIFHRGEDGQWDLSNYHLMDLGHPHHSIRCMAVVYDRVWCGYKNKVHVIQPKTMQIEKS
FDAHPRRESQVRQLAWIGDGVWVSIRLDSTLRLYHAHTHQHLQDVDIEPYVSKMLGTGKL
GFSFVRITALLVAGSRLWVGTGNGVVISIPLTETVVLHRGQLLGLRANKTSPTSGEGARP
GGIIHVYGDDSSDRAASSFIPYCSMAQAQLCFHGHRDAVKFFVSVPGNVLATLNGSVLDS
PAEGPGPAAPASEVEGQKLRNVLVLSGGEGYIDFRIGDGEDDETEEGAGDMSQVKPVLSK
AERSHIIVWQVSYTPE

Sequence length

1336

Interactions

View interactions

	KEGG
	MAPK signaling pathway

Show/Hide Causal Diseases (5)

Disease term	Disease name	dbSNP ID	References
Causal
Developmental delay	Global developmental delay	rs28941770, rs199469464, rs281865469, rs143747297, rs398123009, rs587777428, rs786205133, rs606231459, rs797044854, rs797045027, rs864309504, rs878853160, rs886039902, rs886042046, rs886041291 View all (32 more)	28135719
Mental retardation	Intellectual Disability	rs5742905, rs267607136, rs267607137, rs2131714307, rs267607038, rs267607042, rs80338685, rs137853127, rs80338815, rs28940893, rs387906309, rs121908096, rs121908099, rs587784365, rs121918315 View all (1024 more)	28135719
Hypotonia	Neonatal Hypotonia	rs141138948, rs397517172, rs869312824, rs1583169151
Nystagmus	Nystagmus	rs137852207, rs137852208, rs1928435502, rs137852209, rs137852210, rs1929191668, rs137852211, rs137852212, rs2124209414, rs387906720, rs387906721, rs1602791884, rs786205896
Scoliosis	Scoliosis, unspecified	rs1057518828, rs147296805, rs758163506, rs1555613564, rs1596852902, rs1596853067, rs1596853085

Show/Hide Text Mining Associations (11)

Disease Name	Relationship Type	References
Associations from Text Mining
AA amyloidosis	Associate	33788575
Alzheimer Disease	Inhibit	33788575
Brain Neoplasms	Associate	16141199
Breast Neoplasms	Associate	26504170
Dementia	Associate	37330543
Edema	Associate	35013510
Heredodegenerative Disorders Nervous System	Associate	35013510
Neoplasms	Associate	16141199, 26504170, 32485038
Neurodegenerative Diseases	Associate	37330543
Precursor T Cell Lymphoblastic Leukemia Lymphoma	Associate	24159609
Prostatic Neoplasms Castration Resistant	Associate	32485038

MAPK8IP3 (mitogen-activated protein kinase 8 interacting protein 3)