Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	23125
Gene name	Calmodulin binding transcription activator 2
Gene symbol	CAMTA2
Synonyms (NCBI Gene)	-
Chromosome	17
Chromosome location	17p13.2
Summary	The protein encoded by this gene is a member of the calmodulin-binding transcription activator protein family. Members of this family share a common domain structure that consists of a transcription activation domain, a DNA-binding domain, and a calmoduli

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Show/Hide all (238)

miRTarBase ID	miRNA	Experiments	Reference
MIRT049340	hsa-miR-92a-3p	CLASH	23622248
MIRT861046	hsa-miR-106a	CLIP-seq
MIRT861047	hsa-miR-106b	CLIP-seq
MIRT861048	hsa-miR-124	CLIP-seq
MIRT861049	hsa-miR-1268	CLIP-seq
MIRT861050	hsa-miR-1268b	CLIP-seq
MIRT861051	hsa-miR-1321	CLIP-seq
MIRT861052	hsa-miR-151-5p	CLIP-seq
MIRT861053	hsa-miR-17	CLIP-seq
MIRT861054	hsa-miR-20a	CLIP-seq
MIRT861055	hsa-miR-20b	CLIP-seq
MIRT861056	hsa-miR-2682	CLIP-seq
MIRT861057	hsa-miR-28-5p	CLIP-seq
MIRT861058	hsa-miR-3139	CLIP-seq
MIRT861059	hsa-miR-3184	CLIP-seq
MIRT861060	hsa-miR-34a	CLIP-seq
MIRT861061	hsa-miR-34c-5p	CLIP-seq
MIRT861062	hsa-miR-3714	CLIP-seq
MIRT861063	hsa-miR-371b-3p	CLIP-seq
MIRT861064	hsa-miR-3910	CLIP-seq
MIRT861065	hsa-miR-3918	CLIP-seq
MIRT861066	hsa-miR-423-5p	CLIP-seq
MIRT861067	hsa-miR-4261	CLIP-seq
MIRT861068	hsa-miR-4419a	CLIP-seq
MIRT861069	hsa-miR-4433	CLIP-seq
MIRT861070	hsa-miR-4459	CLIP-seq
MIRT861071	hsa-miR-4487	CLIP-seq
MIRT861072	hsa-miR-4496	CLIP-seq
MIRT861073	hsa-miR-449a	CLIP-seq
MIRT861074	hsa-miR-449b	CLIP-seq
MIRT861075	hsa-miR-449c	CLIP-seq
MIRT861076	hsa-miR-4510	CLIP-seq
MIRT861077	hsa-miR-4514	CLIP-seq
MIRT861078	hsa-miR-4640-5p	CLIP-seq
MIRT861079	hsa-miR-4641	CLIP-seq
MIRT861080	hsa-miR-4667-5p	CLIP-seq
MIRT861081	hsa-miR-4692	CLIP-seq
MIRT861082	hsa-miR-4695-5p	CLIP-seq
MIRT861083	hsa-miR-4700-5p	CLIP-seq
MIRT861084	hsa-miR-4721	CLIP-seq
MIRT861085	hsa-miR-4722-5p	CLIP-seq
MIRT861086	hsa-miR-4726-5p	CLIP-seq
MIRT861087	hsa-miR-4731-5p	CLIP-seq
MIRT861088	hsa-miR-4739	CLIP-seq
MIRT861089	hsa-miR-4756-5p	CLIP-seq
MIRT861090	hsa-miR-4768-3p	CLIP-seq
MIRT861091	hsa-miR-4785	CLIP-seq
MIRT861092	hsa-miR-4797-5p	CLIP-seq
MIRT861093	hsa-miR-494	CLIP-seq
MIRT861094	hsa-miR-506	CLIP-seq
MIRT861095	hsa-miR-519d	CLIP-seq
MIRT861096	hsa-miR-541	CLIP-seq
MIRT861097	hsa-miR-654-5p	CLIP-seq
MIRT861098	hsa-miR-708	CLIP-seq
MIRT861099	hsa-miR-93	CLIP-seq
MIRT861100	hsa-miR-933	CLIP-seq
MIRT861101	hsa-miR-939	CLIP-seq
MIRT861102	hsa-miR-940	CLIP-seq
MIRT861102	hsa-miR-940	CLIP-seq
MIRT1955522	hsa-miR-1203	CLIP-seq
MIRT1955523	hsa-miR-1207-5p	CLIP-seq
MIRT1955524	hsa-miR-125a-5p	CLIP-seq
MIRT1955525	hsa-miR-125b	CLIP-seq
MIRT861049	hsa-miR-1268	CLIP-seq
MIRT861050	hsa-miR-1268b	CLIP-seq
MIRT1955526	hsa-miR-1291	CLIP-seq
MIRT1955527	hsa-miR-1292	CLIP-seq
MIRT1955528	hsa-miR-181a	CLIP-seq
MIRT1955529	hsa-miR-181b	CLIP-seq
MIRT1955530	hsa-miR-181c	CLIP-seq
MIRT1955531	hsa-miR-181d	CLIP-seq
MIRT1955532	hsa-miR-1909	CLIP-seq
MIRT1955533	hsa-miR-2277-5p	CLIP-seq
MIRT861056	hsa-miR-2682	CLIP-seq
MIRT861057	hsa-miR-28-5p	CLIP-seq
MIRT1955534	hsa-miR-297	CLIP-seq
MIRT1955535	hsa-miR-299-3p	CLIP-seq
MIRT1955536	hsa-miR-3127-3p	CLIP-seq
MIRT861058	hsa-miR-3139	CLIP-seq
MIRT1955537	hsa-miR-3151	CLIP-seq
MIRT1955538	hsa-miR-3178	CLIP-seq
MIRT1955539	hsa-miR-3180	CLIP-seq
MIRT1955540	hsa-miR-3180-3p	CLIP-seq
MIRT861059	hsa-miR-3184	CLIP-seq
MIRT1955541	hsa-miR-3196	CLIP-seq
MIRT861060	hsa-miR-34a	CLIP-seq
MIRT861061	hsa-miR-34c-5p	CLIP-seq
MIRT1955542	hsa-miR-3664-5p	CLIP-seq
MIRT1955543	hsa-miR-3665	CLIP-seq
MIRT1955544	hsa-miR-3667-5p	CLIP-seq
MIRT861062	hsa-miR-3714	CLIP-seq
MIRT1955545	hsa-miR-412	CLIP-seq
MIRT861066	hsa-miR-423-5p	CLIP-seq
MIRT1955546	hsa-miR-4262	CLIP-seq
MIRT1955547	hsa-miR-4319	CLIP-seq
MIRT1955548	hsa-miR-4447	CLIP-seq
MIRT861070	hsa-miR-4459	CLIP-seq
MIRT1955549	hsa-miR-4471	CLIP-seq
MIRT1955550	hsa-miR-4472	CLIP-seq
MIRT861071	hsa-miR-4487	CLIP-seq
MIRT1955551	hsa-miR-4491	CLIP-seq
MIRT861073	hsa-miR-449a	CLIP-seq
MIRT861074	hsa-miR-449b	CLIP-seq
MIRT861075	hsa-miR-449c	CLIP-seq
MIRT861077	hsa-miR-4514	CLIP-seq
MIRT1955552	hsa-miR-4657	CLIP-seq
MIRT1955553	hsa-miR-4665-3p	CLIP-seq
MIRT861080	hsa-miR-4667-5p	CLIP-seq
MIRT1955554	hsa-miR-4688	CLIP-seq
MIRT861081	hsa-miR-4692	CLIP-seq
MIRT861083	hsa-miR-4700-5p	CLIP-seq
MIRT1955555	hsa-miR-4714-5p	CLIP-seq
MIRT861085	hsa-miR-4722-5p	CLIP-seq
MIRT861087	hsa-miR-4731-5p	CLIP-seq
MIRT1955556	hsa-miR-4742-3p	CLIP-seq
MIRT1955557	hsa-miR-4763-3p	CLIP-seq
MIRT861091	hsa-miR-4785	CLIP-seq
MIRT1955558	hsa-miR-486-3p	CLIP-seq
MIRT861093	hsa-miR-494	CLIP-seq
MIRT861096	hsa-miR-541	CLIP-seq
MIRT1955559	hsa-miR-567	CLIP-seq
MIRT861097	hsa-miR-654-5p	CLIP-seq
MIRT1955560	hsa-miR-657	CLIP-seq
MIRT861098	hsa-miR-708	CLIP-seq
MIRT861100	hsa-miR-933	CLIP-seq
MIRT861101	hsa-miR-939	CLIP-seq
MIRT861102	hsa-miR-940	CLIP-seq
MIRT1955523	hsa-miR-1207-5p	CLIP-seq
MIRT861049	hsa-miR-1268	CLIP-seq
MIRT861050	hsa-miR-1268b	CLIP-seq
MIRT1955527	hsa-miR-1292	CLIP-seq
MIRT861051	hsa-miR-1321	CLIP-seq
MIRT2193211	hsa-miR-139-3p	CLIP-seq
MIRT1955528	hsa-miR-181a	CLIP-seq
MIRT1955529	hsa-miR-181b	CLIP-seq
MIRT1955530	hsa-miR-181c	CLIP-seq
MIRT1955531	hsa-miR-181d	CLIP-seq
MIRT1955532	hsa-miR-1909	CLIP-seq
MIRT861057	hsa-miR-28-5p	CLIP-seq
MIRT861058	hsa-miR-3139	CLIP-seq
MIRT2193212	hsa-miR-3144-5p	CLIP-seq
MIRT861059	hsa-miR-3184	CLIP-seq
MIRT2193213	hsa-miR-3191	CLIP-seq
MIRT2193214	hsa-miR-337-3p	CLIP-seq
MIRT1955544	hsa-miR-3667-5p	CLIP-seq
MIRT2193215	hsa-miR-3919	CLIP-seq
MIRT861066	hsa-miR-423-5p	CLIP-seq
MIRT861067	hsa-miR-4261	CLIP-seq
MIRT1955546	hsa-miR-4262	CLIP-seq
MIRT861068	hsa-miR-4419a	CLIP-seq
MIRT861070	hsa-miR-4459	CLIP-seq
MIRT1955549	hsa-miR-4471	CLIP-seq
MIRT861071	hsa-miR-4487	CLIP-seq
MIRT861072	hsa-miR-4496	CLIP-seq
MIRT861076	hsa-miR-4510	CLIP-seq
MIRT861077	hsa-miR-4514	CLIP-seq
MIRT2193216	hsa-miR-4652-5p	CLIP-seq
MIRT861080	hsa-miR-4667-5p	CLIP-seq
MIRT1955554	hsa-miR-4688	CLIP-seq
MIRT861081	hsa-miR-4692	CLIP-seq
MIRT861083	hsa-miR-4700-5p	CLIP-seq
MIRT861085	hsa-miR-4722-5p	CLIP-seq
MIRT861087	hsa-miR-4731-5p	CLIP-seq
MIRT861088	hsa-miR-4739	CLIP-seq
MIRT2193217	hsa-miR-4756-3p	CLIP-seq
MIRT861089	hsa-miR-4756-5p	CLIP-seq
MIRT1955557	hsa-miR-4763-3p	CLIP-seq
MIRT861091	hsa-miR-4785	CLIP-seq
MIRT2193218	hsa-miR-4787-5p	CLIP-seq
MIRT1955558	hsa-miR-486-3p	CLIP-seq
MIRT861093	hsa-miR-494	CLIP-seq
MIRT861096	hsa-miR-541	CLIP-seq
MIRT861097	hsa-miR-654-5p	CLIP-seq
MIRT861098	hsa-miR-708	CLIP-seq
MIRT861101	hsa-miR-939	CLIP-seq
MIRT861102	hsa-miR-940	CLIP-seq
MIRT2385518	hsa-miR-22	CLIP-seq
MIRT2385519	hsa-miR-320a	CLIP-seq
MIRT2385520	hsa-miR-320b	CLIP-seq
MIRT2385521	hsa-miR-320c	CLIP-seq
MIRT2385522	hsa-miR-320d	CLIP-seq
MIRT2385523	hsa-miR-4429	CLIP-seq
MIRT861048	hsa-miR-124	CLIP-seq
MIRT861049	hsa-miR-1268	CLIP-seq
MIRT861050	hsa-miR-1268b	CLIP-seq
MIRT1955527	hsa-miR-1292	CLIP-seq
MIRT2193211	hsa-miR-139-3p	CLIP-seq
MIRT1955528	hsa-miR-181a	CLIP-seq
MIRT1955529	hsa-miR-181b	CLIP-seq
MIRT1955530	hsa-miR-181c	CLIP-seq
MIRT1955531	hsa-miR-181d	CLIP-seq
MIRT861056	hsa-miR-2682	CLIP-seq
MIRT861059	hsa-miR-3184	CLIP-seq
MIRT861060	hsa-miR-34a	CLIP-seq
MIRT861061	hsa-miR-34c-5p	CLIP-seq
MIRT861062	hsa-miR-3714	CLIP-seq
MIRT861064	hsa-miR-3910	CLIP-seq
MIRT2193215	hsa-miR-3919	CLIP-seq
MIRT861066	hsa-miR-423-5p	CLIP-seq
MIRT1955546	hsa-miR-4262	CLIP-seq
MIRT1955549	hsa-miR-4471	CLIP-seq
MIRT861073	hsa-miR-449a	CLIP-seq
MIRT861074	hsa-miR-449b	CLIP-seq
MIRT861075	hsa-miR-449c	CLIP-seq
MIRT2193217	hsa-miR-4756-3p	CLIP-seq
MIRT861093	hsa-miR-494	CLIP-seq
MIRT861094	hsa-miR-506	CLIP-seq
MIRT861096	hsa-miR-541	CLIP-seq
MIRT861097	hsa-miR-654-5p	CLIP-seq
MIRT861100	hsa-miR-933	CLIP-seq
MIRT861048	hsa-miR-124	CLIP-seq
MIRT861049	hsa-miR-1268	CLIP-seq
MIRT861050	hsa-miR-1268b	CLIP-seq
MIRT1955527	hsa-miR-1292	CLIP-seq
MIRT2193211	hsa-miR-139-3p	CLIP-seq
MIRT1955528	hsa-miR-181a	CLIP-seq
MIRT1955529	hsa-miR-181b	CLIP-seq
MIRT1955530	hsa-miR-181c	CLIP-seq
MIRT1955531	hsa-miR-181d	CLIP-seq
MIRT861056	hsa-miR-2682	CLIP-seq
MIRT861059	hsa-miR-3184	CLIP-seq
MIRT861060	hsa-miR-34a	CLIP-seq
MIRT861061	hsa-miR-34c-5p	CLIP-seq
MIRT861062	hsa-miR-3714	CLIP-seq
MIRT861064	hsa-miR-3910	CLIP-seq
MIRT2193215	hsa-miR-3919	CLIP-seq
MIRT861066	hsa-miR-423-5p	CLIP-seq
MIRT1955546	hsa-miR-4262	CLIP-seq
MIRT1955549	hsa-miR-4471	CLIP-seq
MIRT861073	hsa-miR-449a	CLIP-seq
MIRT861074	hsa-miR-449b	CLIP-seq
MIRT861075	hsa-miR-449c	CLIP-seq
MIRT2193217	hsa-miR-4756-3p	CLIP-seq
MIRT861093	hsa-miR-494	CLIP-seq
MIRT861094	hsa-miR-506	CLIP-seq
MIRT861096	hsa-miR-541	CLIP-seq
MIRT861097	hsa-miR-654-5p	CLIP-seq
MIRT861100	hsa-miR-933	CLIP-seq

Show/Hide all (17)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	IDA	16678093
GO:0003677	Function	DNA binding	IEA
GO:0003682	Function	Chromatin binding	IDA	16678093
GO:0003690	Function	Double-stranded DNA binding	IBA
GO:0003712	Function	Transcription coregulator activity	IBA
GO:0003713	Function	Transcription coactivator activity	IDA	16678093
GO:0005515	Function	Protein binding	IPI	16678093, 25416956, 32296183, 32814053
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	16678093
GO:0005634	Component	Nucleus	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IDA	16678093
GO:0014898	Process	Cardiac muscle hypertrophy in response to stress	IDA	16678093
GO:0042826	Function	Histone deacetylase binding	IDA	16678093
GO:0043565	Function	Sequence-specific DNA binding	IEA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IEA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IGI	16678093

MIM	HGNC	e!Ensembl
611508	18807	ENSG00000108509

O94983

Protein name

Calmodulin-binding transcription activator 2

Protein function

Transcription activator. May act as tumor suppressor.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF03859	CG-1	37 → 149	CG-1 domain	Domain
PF01833	TIG	533 → 614	IPT/TIG domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Detected in brain. Expressed at constant levels throughout the cell cycle in neuroblastoma cell lines. {ECO:0000269|PubMed:11925432, ECO:0000269|PubMed:15138581}.

Sequence

MNTKDTTEVAENSHHLKIFLPKKLLECLPRCPLLPPERLRWNTNEEIASYLITFEKHDEW
LSCAPKTRPQNGSIILYNRKKVKYRKDGYLWKKRKDGKTTREDHMKLKVQGMECLYGCYV
HSSIVPTFHRRCYWLLQNPDIVLVHYLNVPALEDCGKGCSPIFCSISSDRREWLKWSREE
LLGQLKPMFHGIKWSCGNGTEEFSVEHLVQQILDTHPTKPAPRTHACLCSGGLGSGSLTH
KCSSTKHRIISPKVEPRALTLTSIPHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSG
FAEPLEIRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVV
GTEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALE
PQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPPPSPPPSPAPLEPSS
RVGRGEALFGGPVGASELEPFSLSSFPDLMGELISDEAPSIPAPTPQLSPALSTITDFSP
EWSYPEGGVKVLITGPWTEAAEHYSCVFDHIAVPASLVQPGVLRCYCPAHEVGLVSLQVA
GREGPLSASVLFEYRARRFLSLPSTQLDWLSLDDNQFRMSILERLEQMEKRMAEIAAAGQ
VPCQGPDAPPVQDEGQGPGFEARVVVLVESMIPRSTWKGPERLAHGSPFRGMSLLHLAAA
QGYARLIETLSQWRSVETGSLDLEQEVDPLNVDHFSCTPLMWACALGHLEAAVLLFRWNR
QALSIPDSLGRLPLSVAHSRGHVRLARCLEELQRQEPSVEPPFALSPPSSSPDTGLSSVS
SPSELSDGTFSVTSAYSSAPDGSPPPAPLPASEMTMEDMAPGQLSSGVPEAPLLLMDYEA
TNSKGPLSSLPALPPASDDGAAPEDADSPQAVDVIPVDMISLAKQIIEATPERIKREDFV
GLPEAGASMRERTGAVGLSETMSWLASYLENVDHFPSSTPPSELPFERGRLAVPSAPSWA
EFLSASTSGKMESDFALLTLSDHEQRELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQR
CYRKYKQLTWIALKFALYKKMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYRR
RPGPPHRTSATLPARNKGSFLTKKQDQAARKIMRFLRRCRHRMRELKQNQELEGLPQPGL
AT

Sequence length

1202

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
CEREBELLAR DYSFUNCTION WITH VARIABLE COGNITIVE AND BEHAVIORAL ABNORMALITIES	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Malignant tumor of esophagus	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (4)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
Dystonia	Associate	29110692	★★★★★ ★☆☆☆☆ Found in Text Mining only
Fetal Diseases	Associate	36585686	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Associate	25502777	★★★★★ ★☆☆☆☆ Found in Text Mining only
Tetralogy of Fallot	Associate	30582441	★★★★★ ★☆☆☆☆ Found in Text Mining only

CAMTA2 (calmodulin binding transcription activator 2)