Gene Gene information from NCBI Gene database.
Entrez ID 23107
Gene name Mitochondrial ribosomal protein S27
Gene symbol MRPS27
Synonyms (NCBI Gene)
MRP-S27S27mtmS27
Chromosome 5
Chromosome location 5q13.2
Summary Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% prot
miRNA miRNA information provided by mirtarbase database.
666
miRTarBase ID miRNA Experiments Reference
MIRT001060 hsa-miR-218-5p qRT-PCRWestern blot 17998940
MIRT020718 hsa-miR-155-5p Proteomics 18668040
MIRT020718 hsa-miR-155-5p Reporter assay;Other 20584899
MIRT649783 hsa-miR-6793-3p HITS-CLIP 19536157
MIRT649782 hsa-miR-1470 HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
25
GO ID Ontology Definition Evidence Reference
GO:0000049 Function TRNA binding IDA 22841715
GO:0000049 Function TRNA binding IEA
GO:0003723 Function RNA binding IEA
GO:0005515 Function Protein binding IPI 19103604, 22003127, 22841715, 25416956, 28514442, 30215512, 33961781, 35156780, 36012204
GO:0005730 Component Nucleolus IDA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
611989 14512 ENSG00000113048
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q92552
Protein name Small ribosomal subunit protein mS27 (28S ribosomal protein S27, mitochondrial) (MRP-S27) (S27mt) (Mitochondrial ribosomal protein S27)
Protein function RNA-binding component of the mitochondrial small ribosomal subunit (mt-SSU) that plays a role in mitochondrial protein synthesis (PubMed:22841715). Stimulates mitochondrial mRNA translation of subunit components of the mitochondrial electron tra
PDB 3J9M , 6NU2 , 6NU3 , 6RW4 , 6RW5 , 6VLZ , 6VMI , 6ZM5 , 6ZM6 , 6ZS9 , 6ZSA , 6ZSB , 6ZSC , 6ZSD , 6ZSE , 6ZSG , 7A5F , 7A5G , 7A5I , 7A5K , 7L08 , 7OG4 , 7P2E , 7PNX , 7PNY , 7PNZ , 7PO0 , 7PO1 , 7PO2 , 7PO3 , 7QI4 , 7QI5 , 7QI6 , 8ANY , 8CSP , 8CSQ , 8CSR , 8CSS , 8CST , 8CSU , 8K2A , 8OIR , 8OIS , 8QRK , 8QRL , 8QRM , 8QRN , 8RRI , 8XT0 , 8XT2
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF10037 MRP-S27 1 412 Mitochondrial 28S ribosomal protein S27 Family
Tissue specificity TISSUE SPECIFICITY: Overexpressed in hepatocellular carcinoma tissues compared with adjacent non-tumoral liver tissues (at protein level) (PubMed:28714366). Ubiquitous (PubMed:22841715). {ECO:0000269|PubMed:22841715, ECO:0000269|PubMed:28714366}.
Sequence
Sequence length 414
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Mitochondrial translation elongation
Mitochondrial translation termination