Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	23105
Gene name Gene Name - the full gene name approved by the HGNC.	Follistatin like 4
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	FSTL4
Synonyms (NCBI Gene) Gene synonyms aliases	-
Chromosome Chromosome number	5
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	5q31.1

Show/Hide all(236)

miRTarBase ID	miRNA	Experiments	Reference
MIRT658054	hsa-miR-6792-5p	HITS-CLIP	23824327
MIRT615983	hsa-miR-183-3p	HITS-CLIP	23824327
MIRT615982	hsa-miR-4452	HITS-CLIP	23824327
MIRT658053	hsa-miR-4503	HITS-CLIP	23824327
MIRT658052	hsa-miR-7856-5p	HITS-CLIP	23824327
MIRT615989	hsa-miR-4780	HITS-CLIP	23824327
MIRT615988	hsa-miR-6780b-3p	HITS-CLIP	23824327
MIRT615987	hsa-miR-4742-3p	HITS-CLIP	23824327
MIRT615986	hsa-miR-623	HITS-CLIP	23824327
MIRT615985	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT615984	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT615983	hsa-miR-183-3p	HITS-CLIP	23824327
MIRT615982	hsa-miR-4452	HITS-CLIP	23824327
MIRT615981	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT615980	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT615979	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT490710	hsa-miR-4426	PAR-CLIP	23592263
MIRT490711	hsa-miR-4647	PAR-CLIP	23592263
MIRT490709	hsa-miR-4662b	PAR-CLIP	23592263
MIRT490708	hsa-miR-4475	PAR-CLIP	23592263
MIRT490707	hsa-miR-7845-5p	PAR-CLIP	23592263
MIRT490706	hsa-miR-1296-3p	PAR-CLIP	23592263
MIRT490705	hsa-miR-194-3p	PAR-CLIP	23592263
MIRT490704	hsa-miR-7515	PAR-CLIP	23592263
MIRT490703	hsa-miR-4533	PAR-CLIP	23592263
MIRT490702	hsa-miR-3202	PAR-CLIP	23592263
MIRT490701	hsa-miR-4434	PAR-CLIP	23592263
MIRT490700	hsa-miR-4516	PAR-CLIP	23592263
MIRT490699	hsa-miR-5703	PAR-CLIP	23592263
MIRT490698	hsa-miR-6878-5p	PAR-CLIP	23592263
MIRT490696	hsa-miR-3175	PAR-CLIP	23592263
MIRT490697	hsa-miR-4447	PAR-CLIP	23592263
MIRT490695	hsa-miR-4472	PAR-CLIP	23592263
MIRT460823	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT460822	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT460821	hsa-miR-3681-5p	PAR-CLIP	23592263
MIRT460820	hsa-miR-6849-5p	PAR-CLIP	23592263
MIRT460819	hsa-miR-1193	PAR-CLIP	23592263
MIRT460818	hsa-miR-4640-5p	PAR-CLIP	23592263
MIRT460817	hsa-miR-4726-5p	PAR-CLIP	23592263
MIRT460816	hsa-miR-6508-3p	PAR-CLIP	23592263
MIRT460814	hsa-miR-3691-5p	PAR-CLIP	23592263
MIRT460815	hsa-miR-432-3p	PAR-CLIP	23592263
MIRT658054	hsa-miR-6792-5p	HITS-CLIP	23824327
MIRT615983	hsa-miR-183-3p	HITS-CLIP	23824327
MIRT615982	hsa-miR-4452	HITS-CLIP	23824327
MIRT658053	hsa-miR-4503	HITS-CLIP	23824327
MIRT658052	hsa-miR-7856-5p	HITS-CLIP	23824327
MIRT615989	hsa-miR-4780	HITS-CLIP	23824327
MIRT615988	hsa-miR-6780b-3p	HITS-CLIP	23824327
MIRT615987	hsa-miR-4742-3p	HITS-CLIP	23824327
MIRT615986	hsa-miR-623	HITS-CLIP	23824327
MIRT615985	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT615984	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT615983	hsa-miR-183-3p	HITS-CLIP	23824327
MIRT615982	hsa-miR-4452	HITS-CLIP	23824327
MIRT615981	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT615980	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT615979	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT490710	hsa-miR-4426	PAR-CLIP	23592263
MIRT490711	hsa-miR-4647	PAR-CLIP	23592263
MIRT490709	hsa-miR-4662b	PAR-CLIP	23592263
MIRT490708	hsa-miR-4475	PAR-CLIP	23592263
MIRT490707	hsa-miR-7845-5p	PAR-CLIP	23592263
MIRT490706	hsa-miR-1296-3p	PAR-CLIP	23592263
MIRT490705	hsa-miR-194-3p	PAR-CLIP	23592263
MIRT490704	hsa-miR-7515	PAR-CLIP	23592263
MIRT490703	hsa-miR-4533	PAR-CLIP	23592263
MIRT490702	hsa-miR-3202	PAR-CLIP	23592263
MIRT490701	hsa-miR-4434	PAR-CLIP	23592263
MIRT490700	hsa-miR-4516	PAR-CLIP	23592263
MIRT490699	hsa-miR-5703	PAR-CLIP	23592263
MIRT490698	hsa-miR-6878-5p	PAR-CLIP	23592263
MIRT490696	hsa-miR-3175	PAR-CLIP	23592263
MIRT490697	hsa-miR-4447	PAR-CLIP	23592263
MIRT490695	hsa-miR-4472	PAR-CLIP	23592263
MIRT460823	hsa-miR-6758-5p	PAR-CLIP	23592263
MIRT460822	hsa-miR-6856-5p	PAR-CLIP	23592263
MIRT460821	hsa-miR-3681-5p	PAR-CLIP	23592263
MIRT460820	hsa-miR-6849-5p	PAR-CLIP	23592263
MIRT460819	hsa-miR-1193	PAR-CLIP	23592263
MIRT460818	hsa-miR-4640-5p	PAR-CLIP	23592263
MIRT460817	hsa-miR-4726-5p	PAR-CLIP	23592263
MIRT460816	hsa-miR-6508-3p	PAR-CLIP	23592263
MIRT460814	hsa-miR-3691-5p	PAR-CLIP	23592263
MIRT460815	hsa-miR-432-3p	PAR-CLIP	23592263
MIRT1005568	hsa-miR-103a	CLIP-seq
MIRT1005569	hsa-miR-107	CLIP-seq
MIRT1005570	hsa-miR-1270	CLIP-seq
MIRT1005571	hsa-miR-1271	CLIP-seq
MIRT1005572	hsa-miR-1301	CLIP-seq
MIRT1005573	hsa-miR-1304	CLIP-seq
MIRT1005574	hsa-miR-15a	CLIP-seq
MIRT1005575	hsa-miR-15b	CLIP-seq
MIRT1005576	hsa-miR-16	CLIP-seq
MIRT1005577	hsa-miR-1827	CLIP-seq
MIRT1005578	hsa-miR-185	CLIP-seq
MIRT1005579	hsa-miR-188-5p	CLIP-seq
MIRT1005580	hsa-miR-195	CLIP-seq
MIRT1005581	hsa-miR-204	CLIP-seq
MIRT1005582	hsa-miR-211	CLIP-seq
MIRT1005583	hsa-miR-2117	CLIP-seq
MIRT1005584	hsa-miR-3121-3p	CLIP-seq
MIRT1005585	hsa-miR-3148	CLIP-seq
MIRT1005586	hsa-miR-3160-5p	CLIP-seq
MIRT1005587	hsa-miR-3184	CLIP-seq
MIRT1005588	hsa-miR-346	CLIP-seq
MIRT1005589	hsa-miR-3660	CLIP-seq
MIRT1005590	hsa-miR-3682-3p	CLIP-seq
MIRT1005591	hsa-miR-3910	CLIP-seq
MIRT1005592	hsa-miR-3922-5p	CLIP-seq
MIRT1005593	hsa-miR-3941	CLIP-seq
MIRT1005594	hsa-miR-3944-5p	CLIP-seq
MIRT1005595	hsa-miR-410	CLIP-seq
MIRT1005596	hsa-miR-423-5p	CLIP-seq
MIRT1005597	hsa-miR-424	CLIP-seq
MIRT1005598	hsa-miR-4257	CLIP-seq
MIRT1005599	hsa-miR-4273	CLIP-seq
MIRT1005600	hsa-miR-4288	CLIP-seq
MIRT1005601	hsa-miR-4306	CLIP-seq
MIRT1005602	hsa-miR-432	CLIP-seq
MIRT1005603	hsa-miR-4453	CLIP-seq
MIRT1005604	hsa-miR-4461	CLIP-seq
MIRT1005605	hsa-miR-4526	CLIP-seq
MIRT1005606	hsa-miR-4531	CLIP-seq
MIRT1005607	hsa-miR-4538	CLIP-seq
MIRT1005608	hsa-miR-4644	CLIP-seq
MIRT1005609	hsa-miR-466	CLIP-seq
MIRT1005610	hsa-miR-4660	CLIP-seq
MIRT1005611	hsa-miR-4672	CLIP-seq
MIRT1005612	hsa-miR-497	CLIP-seq
MIRT1005613	hsa-miR-5047	CLIP-seq
MIRT1005614	hsa-miR-526b	CLIP-seq
MIRT1005615	hsa-miR-578	CLIP-seq
MIRT1005616	hsa-miR-620	CLIP-seq
MIRT1005617	hsa-miR-629	CLIP-seq
MIRT1005618	hsa-miR-632	CLIP-seq
MIRT1005619	hsa-miR-940	CLIP-seq
MIRT1005620	hsa-miR-96	CLIP-seq
MIRT1998018	hsa-miR-1237	CLIP-seq
MIRT1005570	hsa-miR-1270	CLIP-seq
MIRT1998019	hsa-miR-140-3p	CLIP-seq
MIRT1998020	hsa-miR-149	CLIP-seq
MIRT1005579	hsa-miR-188-5p	CLIP-seq
MIRT1998021	hsa-miR-197	CLIP-seq
MIRT1998022	hsa-miR-223	CLIP-seq
MIRT1998023	hsa-miR-299-3p	CLIP-seq
MIRT1998024	hsa-miR-3064-5p	CLIP-seq
MIRT1005584	hsa-miR-3121-3p	CLIP-seq
MIRT1998025	hsa-miR-3607-5p	CLIP-seq
MIRT1005595	hsa-miR-410	CLIP-seq
MIRT1998026	hsa-miR-4293	CLIP-seq
MIRT1005602	hsa-miR-432	CLIP-seq
MIRT1998027	hsa-miR-4324	CLIP-seq
MIRT1998028	hsa-miR-4329	CLIP-seq
MIRT1005606	hsa-miR-4531	CLIP-seq
MIRT1998029	hsa-miR-4648	CLIP-seq
MIRT1998030	hsa-miR-4654	CLIP-seq
MIRT1998031	hsa-miR-4687-3p	CLIP-seq
MIRT1998032	hsa-miR-4693-3p	CLIP-seq
MIRT1998033	hsa-miR-4697-3p	CLIP-seq
MIRT1998034	hsa-miR-4764-5p	CLIP-seq
MIRT1998035	hsa-miR-4769-5p	CLIP-seq
MIRT1998036	hsa-miR-4794	CLIP-seq
MIRT1998037	hsa-miR-488	CLIP-seq
MIRT1005616	hsa-miR-620	CLIP-seq
MIRT1005617	hsa-miR-629	CLIP-seq
MIRT1005568	hsa-miR-103a	CLIP-seq
MIRT1005569	hsa-miR-107	CLIP-seq
MIRT2231627	hsa-miR-1197	CLIP-seq
MIRT1005570	hsa-miR-1270	CLIP-seq
MIRT1005574	hsa-miR-15a	CLIP-seq
MIRT1005575	hsa-miR-15b	CLIP-seq
MIRT1005576	hsa-miR-16	CLIP-seq
MIRT1005578	hsa-miR-185	CLIP-seq
MIRT1005579	hsa-miR-188-5p	CLIP-seq
MIRT1005580	hsa-miR-195	CLIP-seq
MIRT1005581	hsa-miR-204	CLIP-seq
MIRT1005582	hsa-miR-211	CLIP-seq
MIRT1005583	hsa-miR-2117	CLIP-seq
MIRT1005588	hsa-miR-346	CLIP-seq
MIRT2231628	hsa-miR-34a	CLIP-seq
MIRT2231629	hsa-miR-34c-5p	CLIP-seq
MIRT1005593	hsa-miR-3941	CLIP-seq
MIRT1005597	hsa-miR-424	CLIP-seq
MIRT1005598	hsa-miR-4257	CLIP-seq
MIRT2231630	hsa-miR-4269	CLIP-seq
MIRT1005599	hsa-miR-4273	CLIP-seq
MIRT1005600	hsa-miR-4288	CLIP-seq
MIRT1998026	hsa-miR-4293	CLIP-seq
MIRT1005601	hsa-miR-4306	CLIP-seq
MIRT1005602	hsa-miR-432	CLIP-seq
MIRT1998027	hsa-miR-4324	CLIP-seq
MIRT1998028	hsa-miR-4329	CLIP-seq
MIRT2231631	hsa-miR-4433	CLIP-seq
MIRT2231632	hsa-miR-4436a	CLIP-seq
MIRT2231633	hsa-miR-449a	CLIP-seq
MIRT2231634	hsa-miR-449b	CLIP-seq
MIRT2231635	hsa-miR-4514	CLIP-seq
MIRT1005606	hsa-miR-4531	CLIP-seq
MIRT2231636	hsa-miR-4643	CLIP-seq
MIRT1005608	hsa-miR-4644	CLIP-seq
MIRT1005609	hsa-miR-466	CLIP-seq
MIRT1005611	hsa-miR-4672	CLIP-seq
MIRT2231637	hsa-miR-4692	CLIP-seq
MIRT2231638	hsa-miR-4714-5p	CLIP-seq
MIRT2231639	hsa-miR-4722-5p	CLIP-seq
MIRT2231640	hsa-miR-4742-5p	CLIP-seq
MIRT2231641	hsa-miR-487a	CLIP-seq
MIRT1005612	hsa-miR-497	CLIP-seq
MIRT2231642	hsa-miR-548ac	CLIP-seq
MIRT2231643	hsa-miR-548d-3p	CLIP-seq
MIRT2231644	hsa-miR-548z	CLIP-seq
MIRT1005616	hsa-miR-620	CLIP-seq
MIRT1005618	hsa-miR-632	CLIP-seq
MIRT2231645	hsa-miR-642b	CLIP-seq
MIRT1005619	hsa-miR-940	CLIP-seq
MIRT2388239	hsa-miR-1184	CLIP-seq
MIRT2388240	hsa-miR-1205	CLIP-seq
MIRT2388241	hsa-miR-3158-5p	CLIP-seq
MIRT2449920	hsa-miR-1224-3p	CLIP-seq
MIRT2449921	hsa-miR-1260	CLIP-seq
MIRT2449922	hsa-miR-1260b	CLIP-seq
MIRT2449923	hsa-miR-1280	CLIP-seq
MIRT2449924	hsa-miR-345	CLIP-seq
MIRT2449925	hsa-miR-4286	CLIP-seq
MIRT2449926	hsa-miR-4732-3p	CLIP-seq
MIRT2449927	hsa-miR-532-3p	CLIP-seq
MIRT2681218	hsa-miR-1245b-3p	CLIP-seq
MIRT1998020	hsa-miR-149	CLIP-seq
MIRT2681219	hsa-miR-2116	CLIP-seq
MIRT1998024	hsa-miR-3064-5p	CLIP-seq
MIRT1005599	hsa-miR-4273	CLIP-seq
MIRT2681220	hsa-miR-4677-5p	CLIP-seq
MIRT1998036	hsa-miR-4794	CLIP-seq
MIRT2681221	hsa-miR-591	CLIP-seq

Show/Hide all(9)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005509	Function	Calcium ion binding	IEA
GO:0005576	Component	Extracellular region	IEA
GO:0007275	Process	Multicellular organism development	IBA	21873635
GO:0030141	Component	Secretory granule	IEA
GO:0030154	Process	Cell differentiation	IBA	21873635
GO:0031549	Process	Negative regulation of brain-derived neurotrophic factor receptor signaling pathway	IEA
GO:0048403	Function	Brain-derived neurotrophic factor binding	IEA
GO:0048671	Process	Negative regulation of collateral sprouting	IEA
GO:0061000	Process	Negative regulation of dendritic spine development	IEA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Protein

UniProt ID

Q6MZW2

Protein name

Follistatin-related protein 4 (Follistatin-like protein 4)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF07648	Kazal_2	87 → 133	Kazal-type serine protease inhibitor domain	Domain
PF13927	Ig_3	250 → 324		Domain
PF13927	Ig_3	340 → 417		Domain

Sequence

MKPGGFWLHLTLLGASLPAALGWMDPGTSRGPDVGVGESQAEEPRSFEVTRREGLSSHNE
LLASCGKKFCSRGSRCVLSRKTGEPECQCLEACRPSYVPVCGSDGRFYENHCKLHRAACL
LGKRITVIHSKDCFLKGDTCTMAGYARLKNVLLALQTRLQPLQEGDSRQDPASQKRLLVE
SLFRDLDADGNGHLSSSELAQHVLKKQDLDEDLLGCSPGDLLRFDDYNSDSSLTLREFYM
AFQVVQLSLAPEDRVSVTTVTVGLSTVLTCAVHGDLRPPIIWKRNGLTLNFLDLEDINDF
GEDDSLYITKVTTIHMGNYTCHASGHEQLFQTHVLQVNVPPVIRVYPESQAQEPGVAASL
RCHAEGIPMPRITWLKNGVDVSTQMSKQLSLLANGSELHISSVRYEDTGAYTCIAKNEVG
VDEDISSLFIEDSARKTLANILWREEGLSVGNMFYVFSDDGIIVIHPVDCEIQRHLKPTE
KIFMSYEEICPQREKNATQPCQWVSAVNVRNRYIYVAQPALSRVLVVDIQAQKVLQSIGV
DPLPAKLSYDKSHDQVWVLSWGDVHKSRPSLQVITEASTGQSQHLIRTPFAGVDDFFIPP
TNLIINHIRFGFIFNKSDPAVHKVDLETMMPLKTIGLHHHGCVPQAMAHTHLGGYFFIQC
RQDSPASAARQLLVDSVTDSVLGPNGDVTGTPHTSPDGRFIVSAAADSPWLHVQEITVRG
EIQTLYDLQINSGISDLAFQRSFTESNQYNIYAALHTEPDLLFLELSTGKVGMLKNLKEP
PAGPAQPWGGTHRIMRDSGLFGQYLLTPARESLFLINGRQNTLRCEVSGIKGGTTVVWVG
EV

Sequence length

842

Interactions

View interactions

Show/Hide Unknown Diseases (8)

Disease term	Disease name	Evidence	References	Source
Unknown
Mental depression	Major Depressive Disorder		27622933	ClinVar
Gout	Gout			GWAS
Hypertension	Hypertension			GWAS
Moyamoya Disease	Moyamoya Disease			GWAS
Breast Cancer	Breast Cancer	Importantly, breast cancer patients bearing PRC2 LOF mutations displayed significantly worse prognosis compared with PRC2 wild-type patients		GWAS, CBGDA
Rheumatoid arthritis	Rheumatoid arthritis			GWAS
Stress Disorder	Stress Disorder			GWAS
Prostate cancer	Prostate cancer	Together, these results show that PRRX2 is an oncogene and might play a role in the aggressiveness of PC within the DNPC population.		GWAS, CBGDA

Show/Hide Text Mining Associations (4)

Disease Name	Relationship Type	References
Associations from Text Mining
Colorectal Neoplasms	Associate	39930364
Neoplasms	Associate	39930364
Pancreatic Neoplasms	Associate	30747226
Stroke	Associate	19023099

FSTL4 (follistatin like 4)