Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	23098
Gene name Gene Name - the full gene name approved by the HGNC.	Sterile alpha and TIR motif containing 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	SARM1
Synonyms (NCBI Gene) Gene synonyms aliases	HsTIR, MyD88-5, SAMD2, SARM, hSARM1
Chromosome Chromosome number	17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	17q11.2

Show/Hide all(417)

miRTarBase ID	miRNA	Experiments	Reference
MIRT716214	hsa-miR-1295b-5p	HITS-CLIP	19536157
MIRT716213	hsa-miR-1912	HITS-CLIP	19536157
MIRT716212	hsa-miR-3130-5p	HITS-CLIP	19536157
MIRT716211	hsa-miR-4482-5p	HITS-CLIP	19536157
MIRT716210	hsa-miR-4714-5p	HITS-CLIP	19536157
MIRT286265	hsa-miR-4691-3p	HITS-CLIP	19536157
MIRT716209	hsa-miR-6777-3p	HITS-CLIP	19536157
MIRT716208	hsa-miR-146a-3p	HITS-CLIP	19536157
MIRT716207	hsa-miR-4539	HITS-CLIP	19536157
MIRT716214	hsa-miR-1295b-5p	HITS-CLIP	19536157
MIRT716213	hsa-miR-1912	HITS-CLIP	19536157
MIRT716212	hsa-miR-3130-5p	HITS-CLIP	19536157
MIRT716211	hsa-miR-4482-5p	HITS-CLIP	19536157
MIRT716210	hsa-miR-4714-5p	HITS-CLIP	19536157
MIRT286265	hsa-miR-4691-3p	HITS-CLIP	19536157
MIRT716209	hsa-miR-6777-3p	HITS-CLIP	19536157
MIRT716208	hsa-miR-146a-3p	HITS-CLIP	19536157
MIRT716207	hsa-miR-4539	HITS-CLIP	19536157
MIRT439706	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT439706	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT734451	hsa-miR-124-3p	Immunoprecipitaion (IP), In situ hybridization, Luciferase reporter assay, qRT-PCR	32428870
MIRT716214	hsa-miR-1295b-5p	HITS-CLIP	19536157
MIRT716213	hsa-miR-1912	HITS-CLIP	19536157
MIRT716212	hsa-miR-3130-5p	HITS-CLIP	19536157
MIRT716211	hsa-miR-4482-5p	HITS-CLIP	19536157
MIRT716210	hsa-miR-4714-5p	HITS-CLIP	19536157
MIRT286265	hsa-miR-4691-3p	HITS-CLIP	19536157
MIRT716209	hsa-miR-6777-3p	HITS-CLIP	19536157
MIRT716208	hsa-miR-146a-3p	HITS-CLIP	19536157
MIRT716207	hsa-miR-4539	HITS-CLIP	19536157
MIRT716214	hsa-miR-1295b-5p	HITS-CLIP	19536157
MIRT716213	hsa-miR-1912	HITS-CLIP	19536157
MIRT716212	hsa-miR-3130-5p	HITS-CLIP	19536157
MIRT716211	hsa-miR-4482-5p	HITS-CLIP	19536157
MIRT716210	hsa-miR-4714-5p	HITS-CLIP	19536157
MIRT286265	hsa-miR-4691-3p	HITS-CLIP	19536157
MIRT716209	hsa-miR-6777-3p	HITS-CLIP	19536157
MIRT716208	hsa-miR-146a-3p	HITS-CLIP	19536157
MIRT716207	hsa-miR-4539	HITS-CLIP	19536157
MIRT755849	hsa-miR-330-5p	Luciferase reporter assay, Western blotting, qRT-PCR	34993722
MIRT1326207	hsa-miR-10a	CLIP-seq
MIRT1326208	hsa-miR-10b	CLIP-seq
MIRT1326209	hsa-miR-1205	CLIP-seq
MIRT1326210	hsa-miR-1207-3p	CLIP-seq
MIRT1326211	hsa-miR-1225-3p	CLIP-seq
MIRT1326212	hsa-miR-1233	CLIP-seq
MIRT1326213	hsa-miR-124	CLIP-seq
MIRT1326214	hsa-miR-1263	CLIP-seq
MIRT1326215	hsa-miR-1270	CLIP-seq
MIRT1326216	hsa-miR-1286	CLIP-seq
MIRT1326217	hsa-miR-1291	CLIP-seq
MIRT1326218	hsa-miR-1321	CLIP-seq
MIRT1326219	hsa-miR-182	CLIP-seq
MIRT1326220	hsa-miR-1827	CLIP-seq
MIRT1326221	hsa-miR-199a-5p	CLIP-seq
MIRT1326222	hsa-miR-199b-5p	CLIP-seq
MIRT1326223	hsa-miR-2110	CLIP-seq
MIRT1326224	hsa-miR-2117	CLIP-seq
MIRT1326225	hsa-miR-22	CLIP-seq
MIRT1326226	hsa-miR-2467-3p	CLIP-seq
MIRT1326227	hsa-miR-29a	CLIP-seq
MIRT1326228	hsa-miR-29b	CLIP-seq
MIRT1326229	hsa-miR-29c	CLIP-seq
MIRT1326230	hsa-miR-3065-3p	CLIP-seq
MIRT1326231	hsa-miR-31	CLIP-seq
MIRT1326232	hsa-miR-3151	CLIP-seq
MIRT1326233	hsa-miR-3155	CLIP-seq
MIRT1326234	hsa-miR-3155b	CLIP-seq
MIRT1326235	hsa-miR-3173-3p	CLIP-seq
MIRT1326236	hsa-miR-3184	CLIP-seq
MIRT1326237	hsa-miR-3194-5p	CLIP-seq
MIRT1326238	hsa-miR-328	CLIP-seq
MIRT1326239	hsa-miR-339-5p	CLIP-seq
MIRT1326240	hsa-miR-3614-5p	CLIP-seq
MIRT1326241	hsa-miR-3667-5p	CLIP-seq
MIRT1326242	hsa-miR-3925-3p	CLIP-seq
MIRT1326243	hsa-miR-3929	CLIP-seq
MIRT1326244	hsa-miR-3940-3p	CLIP-seq
MIRT1326245	hsa-miR-423-5p	CLIP-seq
MIRT1326246	hsa-miR-4257	CLIP-seq
MIRT1326247	hsa-miR-4271	CLIP-seq
MIRT1326248	hsa-miR-4273	CLIP-seq
MIRT1326249	hsa-miR-4290	CLIP-seq
MIRT1326250	hsa-miR-4293	CLIP-seq
MIRT1326251	hsa-miR-4418	CLIP-seq
MIRT1326252	hsa-miR-4419a	CLIP-seq
MIRT1326253	hsa-miR-4419b	CLIP-seq
MIRT1326254	hsa-miR-4421	CLIP-seq
MIRT1326255	hsa-miR-4428	CLIP-seq
MIRT1326256	hsa-miR-4433	CLIP-seq
MIRT1326257	hsa-miR-4434	CLIP-seq
MIRT1326258	hsa-miR-4436a	CLIP-seq
MIRT1326259	hsa-miR-4459	CLIP-seq
MIRT1326260	hsa-miR-4468	CLIP-seq
MIRT1326261	hsa-miR-4476	CLIP-seq
MIRT1326262	hsa-miR-4478	CLIP-seq
MIRT1326263	hsa-miR-4492	CLIP-seq
MIRT1326264	hsa-miR-4493	CLIP-seq
MIRT1326265	hsa-miR-4498	CLIP-seq
MIRT1326266	hsa-miR-4504	CLIP-seq
MIRT1326267	hsa-miR-4505	CLIP-seq
MIRT1326268	hsa-miR-4510	CLIP-seq
MIRT1326269	hsa-miR-4516	CLIP-seq
MIRT1326270	hsa-miR-451b	CLIP-seq
MIRT1326271	hsa-miR-4521	CLIP-seq
MIRT1326272	hsa-miR-4531	CLIP-seq
MIRT1326273	hsa-miR-4533	CLIP-seq
MIRT1326274	hsa-miR-4640-5p	CLIP-seq
MIRT1326275	hsa-miR-4649-3p	CLIP-seq
MIRT1326276	hsa-miR-4667-5p	CLIP-seq
MIRT1326277	hsa-miR-4684-5p	CLIP-seq
MIRT1326278	hsa-miR-4695-5p	CLIP-seq
MIRT1326279	hsa-miR-4696	CLIP-seq
MIRT1326280	hsa-miR-4700-5p	CLIP-seq
MIRT1326281	hsa-miR-4708-3p	CLIP-seq
MIRT1326282	hsa-miR-4722-5p	CLIP-seq
MIRT1326283	hsa-miR-4725-3p	CLIP-seq
MIRT1326284	hsa-miR-4725-5p	CLIP-seq
MIRT1326285	hsa-miR-4726-5p	CLIP-seq
MIRT1326286	hsa-miR-4728-5p	CLIP-seq
MIRT1326287	hsa-miR-4731-5p	CLIP-seq
MIRT1326288	hsa-miR-4739	CLIP-seq
MIRT1326289	hsa-miR-4753-5p	CLIP-seq
MIRT1326290	hsa-miR-4756-5p	CLIP-seq
MIRT1326291	hsa-miR-4772-5p	CLIP-seq
MIRT1326292	hsa-miR-4779	CLIP-seq
MIRT1326293	hsa-miR-4786-3p	CLIP-seq
MIRT1326294	hsa-miR-4786-5p	CLIP-seq
MIRT1326295	hsa-miR-484	CLIP-seq
MIRT1326296	hsa-miR-485-5p	CLIP-seq
MIRT1326297	hsa-miR-504	CLIP-seq
MIRT1326298	hsa-miR-506	CLIP-seq
MIRT1326299	hsa-miR-508-5p	CLIP-seq
MIRT1326300	hsa-miR-509-3-5p	CLIP-seq
MIRT1326301	hsa-miR-509-3p	CLIP-seq
MIRT1326302	hsa-miR-509-5p	CLIP-seq
MIRT1326303	hsa-miR-520a-5p	CLIP-seq
MIRT1326304	hsa-miR-520d-5p	CLIP-seq
MIRT1326305	hsa-miR-524-5p	CLIP-seq
MIRT1326306	hsa-miR-525-5p	CLIP-seq
MIRT1326307	hsa-miR-544b	CLIP-seq
MIRT1326308	hsa-miR-561	CLIP-seq
MIRT1326309	hsa-miR-593	CLIP-seq
MIRT1326310	hsa-miR-610	CLIP-seq
MIRT1326311	hsa-miR-620	CLIP-seq
MIRT1326312	hsa-miR-661	CLIP-seq
MIRT1326313	hsa-miR-665	CLIP-seq
MIRT1326314	hsa-miR-668	CLIP-seq
MIRT1326315	hsa-miR-671-5p	CLIP-seq
MIRT1326316	hsa-miR-762	CLIP-seq
MIRT1326317	hsa-miR-765	CLIP-seq
MIRT1326318	hsa-miR-766	CLIP-seq
MIRT1326319	hsa-miR-940	CLIP-seq
MIRT1326256	hsa-miR-4433	CLIP-seq
MIRT1326259	hsa-miR-4459	CLIP-seq
MIRT1326211	hsa-miR-1225-3p	CLIP-seq
MIRT1326212	hsa-miR-1233	CLIP-seq
MIRT2096830	hsa-miR-1234	CLIP-seq
MIRT2096831	hsa-miR-1254	CLIP-seq
MIRT2096832	hsa-miR-125a-3p	CLIP-seq
MIRT2096833	hsa-miR-1260	CLIP-seq
MIRT2096834	hsa-miR-1260b	CLIP-seq
MIRT1326220	hsa-miR-1827	CLIP-seq
MIRT2096835	hsa-miR-188-3p	CLIP-seq
MIRT2096836	hsa-miR-200b	CLIP-seq
MIRT2096837	hsa-miR-200c	CLIP-seq
MIRT1326223	hsa-miR-2110	CLIP-seq
MIRT2096838	hsa-miR-214	CLIP-seq
MIRT2096839	hsa-miR-218	CLIP-seq
MIRT2096840	hsa-miR-224	CLIP-seq
MIRT2096841	hsa-miR-3116	CLIP-seq
MIRT2096842	hsa-miR-3120-5p	CLIP-seq
MIRT2096843	hsa-miR-3140-3p	CLIP-seq
MIRT2096844	hsa-miR-3144-5p	CLIP-seq
MIRT2096845	hsa-miR-3150a-3p	CLIP-seq
MIRT2096846	hsa-miR-3156-3p	CLIP-seq
MIRT1326235	hsa-miR-3173-3p	CLIP-seq
MIRT2096847	hsa-miR-3189-3p	CLIP-seq
MIRT2096848	hsa-miR-3191	CLIP-seq
MIRT1326240	hsa-miR-3614-5p	CLIP-seq
MIRT2096849	hsa-miR-3619-5p	CLIP-seq
MIRT2096850	hsa-miR-3649	CLIP-seq
MIRT2096851	hsa-miR-3664-3p	CLIP-seq
MIRT2096852	hsa-miR-3915	CLIP-seq
MIRT2096853	hsa-miR-3918	CLIP-seq
MIRT2096854	hsa-miR-3921	CLIP-seq
MIRT2096855	hsa-miR-3928	CLIP-seq
MIRT1326243	hsa-miR-3929	CLIP-seq
MIRT2096856	hsa-miR-3934	CLIP-seq
MIRT2096857	hsa-miR-3943	CLIP-seq
MIRT2096858	hsa-miR-4251	CLIP-seq
MIRT2096859	hsa-miR-4254	CLIP-seq
MIRT1326247	hsa-miR-4271	CLIP-seq
MIRT2096860	hsa-miR-429	CLIP-seq
MIRT1326249	hsa-miR-4290	CLIP-seq
MIRT2096861	hsa-miR-4301	CLIP-seq
MIRT2096862	hsa-miR-4303	CLIP-seq
MIRT2096863	hsa-miR-4329	CLIP-seq
MIRT1326253	hsa-miR-4419b	CLIP-seq
MIRT1326255	hsa-miR-4428	CLIP-seq
MIRT1326256	hsa-miR-4433	CLIP-seq
MIRT2096864	hsa-miR-4446-3p	CLIP-seq
MIRT1326259	hsa-miR-4459	CLIP-seq
MIRT2096865	hsa-miR-4471	CLIP-seq
MIRT1326262	hsa-miR-4478	CLIP-seq
MIRT2096866	hsa-miR-4488	CLIP-seq
MIRT1326263	hsa-miR-4492	CLIP-seq
MIRT1326265	hsa-miR-4498	CLIP-seq
MIRT1326267	hsa-miR-4505	CLIP-seq
MIRT1326271	hsa-miR-4521	CLIP-seq
MIRT1326275	hsa-miR-4649-3p	CLIP-seq
MIRT2096867	hsa-miR-4652-5p	CLIP-seq
MIRT2096868	hsa-miR-4653-5p	CLIP-seq
MIRT2096869	hsa-miR-4659a-5p	CLIP-seq
MIRT2096870	hsa-miR-4659b-5p	CLIP-seq
MIRT1326276	hsa-miR-4667-5p	CLIP-seq
MIRT2096871	hsa-miR-4690-3p	CLIP-seq
MIRT1326278	hsa-miR-4695-5p	CLIP-seq
MIRT2096872	hsa-miR-4697-5p	CLIP-seq
MIRT1326280	hsa-miR-4700-5p	CLIP-seq
MIRT2096873	hsa-miR-4711-3p	CLIP-seq
MIRT1326282	hsa-miR-4722-5p	CLIP-seq
MIRT1326283	hsa-miR-4725-3p	CLIP-seq
MIRT1326287	hsa-miR-4731-5p	CLIP-seq
MIRT2096874	hsa-miR-4768-3p	CLIP-seq
MIRT2096875	hsa-miR-4769-3p	CLIP-seq
MIRT1326291	hsa-miR-4772-5p	CLIP-seq
MIRT2096876	hsa-miR-4792	CLIP-seq
MIRT1326296	hsa-miR-485-5p	CLIP-seq
MIRT2096877	hsa-miR-543	CLIP-seq
MIRT1326310	hsa-miR-610	CLIP-seq
MIRT2096878	hsa-miR-645	CLIP-seq
MIRT1326312	hsa-miR-661	CLIP-seq
MIRT1326313	hsa-miR-665	CLIP-seq
MIRT1326314	hsa-miR-668	CLIP-seq
MIRT2096879	hsa-miR-761	CLIP-seq
MIRT1326316	hsa-miR-762	CLIP-seq
MIRT2096880	hsa-miR-764	CLIP-seq
MIRT2096881	hsa-miR-938	CLIP-seq
MIRT1326319	hsa-miR-940	CLIP-seq
MIRT1326207	hsa-miR-10a	CLIP-seq
MIRT1326208	hsa-miR-10b	CLIP-seq
MIRT2321150	hsa-miR-1178	CLIP-seq
MIRT1326211	hsa-miR-1225-3p	CLIP-seq
MIRT2321151	hsa-miR-1231	CLIP-seq
MIRT1326212	hsa-miR-1233	CLIP-seq
MIRT2321152	hsa-miR-1245b-5p	CLIP-seq
MIRT2096831	hsa-miR-1254	CLIP-seq
MIRT1326214	hsa-miR-1263	CLIP-seq
MIRT2321153	hsa-miR-1266	CLIP-seq
MIRT2321154	hsa-miR-1285	CLIP-seq
MIRT1326220	hsa-miR-1827	CLIP-seq
MIRT2321155	hsa-miR-192	CLIP-seq
MIRT2321156	hsa-miR-215	CLIP-seq
MIRT2321157	hsa-miR-296-5p	CLIP-seq
MIRT2096841	hsa-miR-3116	CLIP-seq
MIRT2096842	hsa-miR-3120-5p	CLIP-seq
MIRT2321158	hsa-miR-3121-5p	CLIP-seq
MIRT2321159	hsa-miR-3142	CLIP-seq
MIRT1326235	hsa-miR-3173-3p	CLIP-seq
MIRT2321160	hsa-miR-3187-5p	CLIP-seq
MIRT2321161	hsa-miR-326	CLIP-seq
MIRT755849	hsa-miR-330-5p	CLIP-seq
MIRT1326240	hsa-miR-3614-5p	CLIP-seq
MIRT2321162	hsa-miR-3622a-3p	CLIP-seq
MIRT2321163	hsa-miR-3622b-3p	CLIP-seq
MIRT2321164	hsa-miR-3652	CLIP-seq
MIRT2096851	hsa-miR-3664-3p	CLIP-seq
MIRT1326241	hsa-miR-3667-5p	CLIP-seq
MIRT1326243	hsa-miR-3929	CLIP-seq
MIRT2321165	hsa-miR-4288	CLIP-seq
MIRT1326249	hsa-miR-4290	CLIP-seq
MIRT1326253	hsa-miR-4419b	CLIP-seq
MIRT2321166	hsa-miR-4430	CLIP-seq
MIRT1326256	hsa-miR-4433	CLIP-seq
MIRT1326259	hsa-miR-4459	CLIP-seq
MIRT1326262	hsa-miR-4478	CLIP-seq
MIRT1326264	hsa-miR-4493	CLIP-seq
MIRT1326267	hsa-miR-4505	CLIP-seq
MIRT2321167	hsa-miR-4518	CLIP-seq
MIRT1326270	hsa-miR-451b	CLIP-seq
MIRT1326271	hsa-miR-4521	CLIP-seq
MIRT1326273	hsa-miR-4533	CLIP-seq
MIRT1326275	hsa-miR-4649-3p	CLIP-seq
MIRT2321168	hsa-miR-4650-5p	CLIP-seq
MIRT1326279	hsa-miR-4696	CLIP-seq
MIRT2321169	hsa-miR-4721	CLIP-seq
MIRT1326282	hsa-miR-4722-5p	CLIP-seq
MIRT1326284	hsa-miR-4725-5p	CLIP-seq
MIRT1326286	hsa-miR-4728-5p	CLIP-seq
MIRT2321170	hsa-miR-4747-5p	CLIP-seq
MIRT2321171	hsa-miR-4751	CLIP-seq
MIRT1326289	hsa-miR-4753-5p	CLIP-seq
MIRT2321172	hsa-miR-4755-3p	CLIP-seq
MIRT2096874	hsa-miR-4768-3p	CLIP-seq
MIRT1326296	hsa-miR-485-5p	CLIP-seq
MIRT1326297	hsa-miR-504	CLIP-seq
MIRT1326310	hsa-miR-610	CLIP-seq
MIRT2321173	hsa-miR-612	CLIP-seq
MIRT2321174	hsa-miR-632	CLIP-seq
MIRT1326312	hsa-miR-661	CLIP-seq
MIRT1326313	hsa-miR-665	CLIP-seq
MIRT1326314	hsa-miR-668	CLIP-seq
MIRT1326319	hsa-miR-940	CLIP-seq
MIRT1326211	hsa-miR-1225-3p	CLIP-seq
MIRT1326212	hsa-miR-1233	CLIP-seq
MIRT1326220	hsa-miR-1827	CLIP-seq
MIRT2096851	hsa-miR-3664-3p	CLIP-seq
MIRT1326256	hsa-miR-4433	CLIP-seq
MIRT1326259	hsa-miR-4459	CLIP-seq
MIRT2394036	hsa-miR-4522	CLIP-seq
MIRT1326275	hsa-miR-4649-3p	CLIP-seq
MIRT2096874	hsa-miR-4768-3p	CLIP-seq
MIRT2096838	hsa-miR-214	CLIP-seq
MIRT2096849	hsa-miR-3619-5p	CLIP-seq
MIRT2440038	hsa-miR-4291	CLIP-seq
MIRT1326282	hsa-miR-4722-5p	CLIP-seq
MIRT2096879	hsa-miR-761	CLIP-seq
MIRT2440039	hsa-miR-922	CLIP-seq
MIRT2096838	hsa-miR-214	CLIP-seq
MIRT2096849	hsa-miR-3619-5p	CLIP-seq
MIRT2440038	hsa-miR-4291	CLIP-seq
MIRT1326282	hsa-miR-4722-5p	CLIP-seq
MIRT2096879	hsa-miR-761	CLIP-seq
MIRT2440039	hsa-miR-922	CLIP-seq
MIRT2458815	hsa-miR-1207-5p	CLIP-seq
MIRT2458816	hsa-miR-1237	CLIP-seq
MIRT1326213	hsa-miR-124	CLIP-seq
MIRT2458817	hsa-miR-1273d	CLIP-seq
MIRT2458818	hsa-miR-1587	CLIP-seq
MIRT2458819	hsa-miR-3074-5p	CLIP-seq
MIRT2096842	hsa-miR-3120-5p	CLIP-seq
MIRT2096847	hsa-miR-3189-3p	CLIP-seq
MIRT2458820	hsa-miR-3607-3p	CLIP-seq
MIRT2458821	hsa-miR-3662	CLIP-seq
MIRT2458822	hsa-miR-3682-3p	CLIP-seq
MIRT2458823	hsa-miR-3686	CLIP-seq
MIRT2458824	hsa-miR-370	CLIP-seq
MIRT2458825	hsa-miR-4260	CLIP-seq
MIRT2458826	hsa-miR-4299	CLIP-seq
MIRT2458827	hsa-miR-4302	CLIP-seq
MIRT2458828	hsa-miR-4312	CLIP-seq
MIRT2458829	hsa-miR-4450	CLIP-seq
MIRT2458830	hsa-miR-4456	CLIP-seq
MIRT2458831	hsa-miR-4528	CLIP-seq
MIRT2458832	hsa-miR-4661-3p	CLIP-seq
MIRT2458833	hsa-miR-4674	CLIP-seq
MIRT2458834	hsa-miR-4736	CLIP-seq
MIRT2458835	hsa-miR-4762-3p	CLIP-seq
MIRT2458836	hsa-miR-4763-3p	CLIP-seq
MIRT2458837	hsa-miR-494	CLIP-seq
MIRT2458838	hsa-miR-495	CLIP-seq
MIRT1326298	hsa-miR-506	CLIP-seq
MIRT2458839	hsa-miR-548q	CLIP-seq
MIRT2458840	hsa-miR-616	CLIP-seq
MIRT2458841	hsa-miR-635	CLIP-seq
MIRT1326312	hsa-miR-661	CLIP-seq
MIRT2466002	hsa-miR-149	CLIP-seq
MIRT2466003	hsa-miR-3176	CLIP-seq
MIRT2466004	hsa-miR-3663-3p	CLIP-seq
MIRT2466005	hsa-miR-3922-3p	CLIP-seq
MIRT2458827	hsa-miR-4302	CLIP-seq
MIRT2466006	hsa-miR-4783-3p	CLIP-seq
MIRT2096876	hsa-miR-4792	CLIP-seq
MIRT2466007	hsa-miR-760	CLIP-seq
MIRT1326207	hsa-miR-10a	CLIP-seq
MIRT1326208	hsa-miR-10b	CLIP-seq
MIRT1326211	hsa-miR-1225-3p	CLIP-seq
MIRT1326212	hsa-miR-1233	CLIP-seq
MIRT2466002	hsa-miR-149	CLIP-seq
MIRT2466003	hsa-miR-3176	CLIP-seq
MIRT2617348	hsa-miR-3180-5p	CLIP-seq
MIRT1326239	hsa-miR-339-5p	CLIP-seq
MIRT1326240	hsa-miR-3614-5p	CLIP-seq
MIRT2466004	hsa-miR-3663-3p	CLIP-seq
MIRT1326241	hsa-miR-3667-5p	CLIP-seq
MIRT2466005	hsa-miR-3922-3p	CLIP-seq
MIRT1326254	hsa-miR-4421	CLIP-seq
MIRT1326256	hsa-miR-4433	CLIP-seq
MIRT1326270	hsa-miR-451b	CLIP-seq
MIRT1326279	hsa-miR-4696	CLIP-seq
MIRT1326284	hsa-miR-4725-5p	CLIP-seq
MIRT2466006	hsa-miR-4783-3p	CLIP-seq
MIRT2096876	hsa-miR-4792	CLIP-seq
MIRT1326297	hsa-miR-504	CLIP-seq
MIRT1326303	hsa-miR-520a-5p	CLIP-seq
MIRT1326306	hsa-miR-525-5p	CLIP-seq
MIRT1326309	hsa-miR-593	CLIP-seq
MIRT1326313	hsa-miR-665	CLIP-seq
MIRT2466007	hsa-miR-760	CLIP-seq
MIRT1326207	hsa-miR-10a	CLIP-seq
MIRT1326208	hsa-miR-10b	CLIP-seq
MIRT2321151	hsa-miR-1231	CLIP-seq
MIRT2466002	hsa-miR-149	CLIP-seq
MIRT2690210	hsa-miR-3163	CLIP-seq
MIRT2466003	hsa-miR-3176	CLIP-seq
MIRT2617348	hsa-miR-3180-5p	CLIP-seq
MIRT1326239	hsa-miR-339-5p	CLIP-seq
MIRT2466004	hsa-miR-3663-3p	CLIP-seq
MIRT1326241	hsa-miR-3667-5p	CLIP-seq
MIRT2466005	hsa-miR-3922-3p	CLIP-seq
MIRT2690211	hsa-miR-4282	CLIP-seq
MIRT2321165	hsa-miR-4288	CLIP-seq
MIRT1326254	hsa-miR-4421	CLIP-seq
MIRT1326270	hsa-miR-451b	CLIP-seq
MIRT1326279	hsa-miR-4696	CLIP-seq
MIRT1326284	hsa-miR-4725-5p	CLIP-seq
MIRT2690212	hsa-miR-4742-3p	CLIP-seq
MIRT2466006	hsa-miR-4783-3p	CLIP-seq
MIRT2096876	hsa-miR-4792	CLIP-seq
MIRT1326297	hsa-miR-504	CLIP-seq
MIRT1326303	hsa-miR-520a-5p	CLIP-seq
MIRT1326306	hsa-miR-525-5p	CLIP-seq
MIRT2690213	hsa-miR-568	CLIP-seq
MIRT1326309	hsa-miR-593	CLIP-seq
MIRT2321174	hsa-miR-632	CLIP-seq
MIRT2466007	hsa-miR-760	CLIP-seq

Show/Hide all(27)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003953	Function	NAD+ nucleosidase activity	IDA	28334607, 31128467, 31439792, 31439793
GO:0005515	Function	Protein binding	IPI	17258210, 26592460
GO:0005737	Component	Cytoplasm	ISS
GO:0005739	Component	Mitochondrion	IDA	22145856
GO:0005829	Component	Cytosol	TAS
GO:0005874	Component	Microtubule	ISS
GO:0007165	Process	Signal transduction	IEA
GO:0007399	Process	Nervous system development	IEA
GO:0009749	Process	Response to glucose	IEA
GO:0019677	Process	NAD catabolic process	IDA	25908823, 27671644, 28334607, 31128467, 31439792, 31439793
GO:0030154	Process	Cell differentiation	IEA
GO:0030424	Component	Axon	IEA
GO:0030425	Component	Dendrite	IBA	21873635
GO:0030425	Component	Dendrite	ISS
GO:0031315	Component	Extrinsic component of mitochondrial outer membrane	IEA
GO:0034128	Process	Negative regulation of MyD88-independent toll-like receptor signaling pathway	TAS
GO:0035591	Function	Signaling adaptor activity	IEA
GO:0042981	Process	Regulation of apoptotic process	IEA
GO:0045087	Process	Innate immune response	IEA
GO:0045202	Component	Synapse	ISS
GO:0048678	Process	Response to axon injury	IDA	25908823
GO:0048814	Process	Regulation of dendrite morphogenesis	ISS
GO:0050135	Function	NAD(P)+ nucleosidase activity	IEA
GO:0061809	Function	NAD+ nucleotidase, cyclic ADP-ribose generating	IDA	28334607, 31128467
GO:1901214	Process	Regulation of neuron death	IBA	21873635
GO:1901214	Process	Regulation of neuron death	ISS
GO:1901216	Process	Positive regulation of neuron death	IDA	25908823, 27671644, 28334607

MIM	HGNC	e!Ensembl
607732	17074	ENSG00000004139

Protein

UniProt ID

Q6SZW1

Protein name

NAD(+) hydrolase SARM1 (NADase SARM1) (hSARM1) (EC 3.2.2.6) (NADP(+) hydrolase SARM1) (EC 3.2.2.-) (Sterile alpha and Armadillo repeat protein) (Sterile alpha and TIR motif-containing protein 1) (Sterile alpha motif domain-containing protein 2) (MyD88-5)

Protein function

NAD(+) hydrolase, which plays a key role in axonal degeneration following injury by regulating NAD(+) metabolism (PubMed:25908823, PubMed:27671644, PubMed:28334607). Acts as a negative regulator of MYD88- and TRIF-dependent toll-like receptor si

PDB

6O0Q , 6O0R , 6O0S , 6O0T , 6O0U , 6O0V , 6O1B , 6QWV , 6WPK , 6ZFX , 6ZG0 , 6ZG1 , 7ANW , 7CM5 , 7CM6 , 7CM7 , 7DJT , 7KNQ , 7LD0 , 7NAG , 7NAH , 7NAI , 7NAJ , 7NAK , 7NAL , 7QG0 , 8D0C , 8D0D , 8D0E , 8D0F , 8D0G , 8D0H , 8D0I , 8D0J , 8GNI , 8GNJ , 8GQ5 , 8P2L , 9L2D , 9L2E

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF07647	SAM_2	409 → 474	SAM domain (Sterile alpha motif)	Domain
PF07647	SAM_2	479 → 546	SAM domain (Sterile alpha motif)	Domain
PF13676	TIR_2	564 → 696	TIR domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Predominantly expressed in brain, kidney and liver. Expressed at lower level in placenta. {ECO:0000269|PubMed:11386760, ECO:0000269|PubMed:17724133}.

Sequence

MVLTLLLSAYKLCRFFAMSGPRPGAERLAVPGPDGGGGTGPWWAAGGRGPREVSPGAGTE
VQDALERALPELQQALSALKQAGGARAVGAGLAEVFQLVEEAWLLPAVGREVAQGLCDAI
RLDGGLDLLLRLLQAPELETRVQAARLLEQILVAENRDRVARIGLGVILNLAKEREPVEL
ARSVAGILEHMFKHSEETCQRLVAAGGLDAVLYWCRRTDPALLRHCALALGNCALHGGQA
VQRRMVEKRAAEWLFPLAFSKEDELLRLHACLAVAVLATNKEVEREVERSGTLALVEPLV
ASLDPGRFARCLVDASDTSQGRGPDDLQRLVPLLDSNRLEAQCIGAFYLCAEAAIKSLQG
KTKVFSDIGAIQSLKRLVSYSTNGTKSALAKRALRLLGEEVPRPILPSVPSWKEAEVQTW
LQQIGFSKYCESFREQQVDGDLLLRLTEEELQTDLGMKSGITRKRFFRELTELKTFANYS
TCDRSNLADWLGSLDPRFRQYTYGLVSCGLDRSLLHRVSEQQLLEDCGIHLGVHRARILT
AAREMLHSPLPCTGGKPSGDTPDVFISYRRNSGSQLASLLKVHLQLHGFSVFIDVEKLEA
GKFEDKLIQSVMGARNFVLVLSPGALDKCMQDHDCKDWVHKEIVTALSCGKNIVPIIDGF
EWPEPQVLPEDMQAVLTFNGIKWSHEYQEATIEKIIRFLQGRSSRDSSAGSDTSLEGAAP
MGPT

Sequence length

724

Interactions

View interactions

	KEGG		Reactome
	Nicotinate and nicotinamide metabolism Metabolic pathways		MyD88-independent TLR4 cascade Toll Like Receptor 3 (TLR3) Cascade Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon IKK complex recruitment mediated by RIP1 TRAF6-mediated induction of TAK1 complex within TLR4 complex

Show/Hide Causal Diseases (3)

Disease term	Disease name	dbSNP ID	References
Causal
Amyotrophic lateral sclerosis	Amyotrophic Lateral Sclerosis, AMYOTROPHIC LATERAL SCLEROSIS 6 (disorder), AMYOTROPHIC LATERAL SCLEROSIS 1, AUTOSOMAL RECESSIVE	rs267607084, rs312262720, rs312262752, rs121908287, rs121908288, rs29001584, rs28941475, rs121434378, rs386134173, rs386134174, rs80356730, rs80356727, rs4884357, rs80356717, rs80356733 View all (171 more)	27455348, 28931804
Congenital defect of folate absorption	Folate Malabsorption, Hereditary	rs80338775, rs80338769, rs80338770, rs80338772, rs80338773, rs80338774, rs397515574, rs397515391, rs281875209, rs1597834560
Lateral sclerosis	AMYOTROPHIC LATERAL SCLEROSIS 1, Amyotrophic Lateral Sclerosis, Sporadic	rs386134181, rs386134176, rs386134174, rs386134184, rs386134178, rs1693780539, rs1574698048	28931804

Show/Hide Unknown Diseases (4)

Disease term	Disease name	Source
Unknown
Amyotrophic Lateral Sclerosis	Amyotrophic Lateral Sclerosis	GWAS
Giant Cell Arteritis	Giant Cell Arteritis	GWAS
Diabetes	Diabetes	GWAS
Hypertension	Hypertension	GWAS

Show/Hide Text Mining Associations (15)

Disease Name	Relationship Type	References
Associations from Text Mining
Alzheimer Disease	Associate	32413284
Amyotrophic Lateral Sclerosis	Associate	32413284, 36759259, 37639066
Arthritis Rheumatoid	Associate	33605409
Cystic Fibrosis	Inhibit	31813753
Heredodegenerative Disorders Nervous System	Associate	33548217
Inflammation	Associate	23923041
Neoplasm Metastasis	Stimulate	32428870
Nerve Degeneration	Associate	30333228, 32413284, 33548217
Neurodegenerative Diseases	Associate	30333228, 32828421
Parkinson Disease	Associate	30333228
Peripheral Nervous System Diseases	Associate	33548217
Prostatic Neoplasms	Associate	32428870
Retrograde Degeneration	Associate	33548217
Wallerian Degeneration	Associate	32828421
Wounds and Injuries	Associate	33548217

SARM1 (sterile alpha and TIR motif containing 1)