ARHGAP26 (Rho GTPase activating protein 26)
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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23092 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Rho GTPase activating protein 26 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ARHGAP26 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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GRAF, GRAF1, OPHN1L, OPHN1L1 |
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Chromosome
Chromosome number
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5 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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5q31.3 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||||||||||||
| UniProt ID | Q9UNA1 | |||||||||||||||||||||||||
| Protein name | Rho GTPase-activating protein 26 (GTPase regulator associated with focal adhesion kinase) (GRAF1) (Oligophrenin-1-like protein) (Rho-type GTPase-activating protein 26) | |||||||||||||||||||||||||
| Protein function | GTPase-activating protein for RHOA and CDC42. Facilitates mitochondrial quality control by promoting Parkin-mediated recruitment of autophagosomes to damaged mitochondria (PubMed:38081847). Negatively regulates the growth of human parainfluenza | |||||||||||||||||||||||||
| PDB | 1UGV | |||||||||||||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 814 | |||||||||||||||||||||||||
| Interactions | View interactions | |||||||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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