Gene Gene information from NCBI Gene database.
Entrez ID 23076
Gene name Ribosomal RNA processing 1B
Gene symbol RRP1B
Synonyms (NCBI Gene)
KIAA0179NNP1LNnp1PPP1R136RRP1
Chromosome 21
Chromosome location 21q22.3
miRNA miRNA information provided by mirtarbase database.
617
miRTarBase ID miRNA Experiments Reference
MIRT005231 hsa-let-7b-5p pSILAC 18668040
MIRT025330 hsa-miR-34a-5p Proteomics 21566225
MIRT027588 hsa-miR-98-5p Microarray 19088304
MIRT005231 hsa-let-7b-5p Proteomics 18668040
MIRT047655 hsa-miR-10a-5p CLASH 23622248
Transcription factors Transcription factors information provided by TRRUST V2 database.
1
Transcription factor Regulation Reference
E2F1 Unknown 20040599
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
28
GO ID Ontology Definition Evidence Reference
GO:0000791 Component Euchromatin IEA
GO:0000792 Component Heterochromatin IEA
GO:0001652 Component Granular component IDA 20926688
GO:0003713 Function Transcription coactivator activity IMP 20040599
GO:0003723 Function RNA binding HDA 22658674, 22681889
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
610654 23818 ENSG00000160208
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q14684
Protein name Ribosomal RNA processing protein 1 homolog B (RRP1-like protein B)
Protein function Positively regulates DNA damage-induced apoptosis by acting as a transcriptional coactivator of proapoptotic target genes of the transcriptional activator E2F1 (PubMed:20040599). Likely to play a role in ribosome biogenesis by targeting serine/t
PDB 7T0Y
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05997 Nop52 10 218 Nucleolar protein,Nop52 Family
Sequence
MAPAMQPAEIQFAQRLASSEKGIRDRAVKKLRQYISVKTQRETGGFSQEELLKIWKGLFY
CMWVQDEPLLQEELANTIAQLVHAVNNSAAQHLFIQTFWQTMNREWKGIDRLRLDKYYML
IRLVLRQSFEVLKRNGWEESRIKVFLDVLMKEVLCPESQSPNGVRFHFIDIYLDELSKVG
GKELLADQNLKFIDPFCKIAAKTKDHTLVQTIARGVFE
AIVDQSPFVPEETMEEQKTKVG
DGDLSAEEIPENEVSLRRAVSKKKTALGKNHSRKDGLSDERGRDDCGTFEDTGPLLQFDY
KAVADRLLEMTSRKNTPHFNRKRLSKLIKKFQDLSEGSSISQLSFAEDISADEDDQILSQ
GKHKKKGNKLLEKTNLEKEKGSRVFCVEEEDSESSLQKRRRKKKKKHHLQPENPGPGGAA
PSLEQNRGREPEASGLKALKARVAEPGAEATSSTGEESGSEHPPAVPMHNKRKRPRKKSP
RAHREMLESAVLPPEDMSQSGPSGSHPQGPRGSPTGGAQLLKRKRKLGVVPVNGSGLSTP
AWPPLQQEGPPTGPAEGANSHTTLPQRRRLQKKKAGPGSLELCGLPSQKTASLKKRKKMR
VMSNLVEHNGVLESEAGQPQALGSSGTCSSLKKQKLRAESDFVKFDTPFLPKPLFFRRAK
SSTATHPPGPAVQLNKTPSSSKKVTFGLNRNMTAEFKKTDKSILVSPTGPSRVAFDPEQK
PLHGVLKTPTSSPASSPLVAKKPLTTTPRRRPRAMDFF
Sequence length 758
Interactions View interactions