ERP44 (endoplasmic reticulum protein 44)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 23071 |
| Gene name | Endoplasmic reticulum protein 44 |
| Gene symbol | ERP44 |
| Synonyms (NCBI Gene) |
PDIA10TXNDC4
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| Chromosome | 9 |
| Chromosome location | 9q31.1 |
| Summary | This gene encodes a member of the protein disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins. It has an inferred N-terminal signal peptide, a catalytically active thioredoxin (TRX) domain, two TRX-like domains and a C-terminal ER-rete |
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miRNA
miRNA information provided by mirtarbase database.
316
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Transcription factors
Transcription factors information provided by TRRUST V2 database.
2
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
21
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9BS26 | |||||||||||||||
| Protein name | Endoplasmic reticulum resident protein 44 (ER protein 44) (ERp44) (Thioredoxin domain-containing protein 4) | |||||||||||||||
| Protein function | Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif (PubMed:11847130, PubMed:14517240). Inhibits the calcium channel activity of ITPR1 (PubMed:15652 | |||||||||||||||
| PDB | 2R2J , 5GU6 , 5GU7 , 5HQP , 5XWM | |||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 406 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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