Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
23042
Gene name Gene Name - the full gene name approved by the HGNC.
Pyridoxal dependent decarboxylase domain containing 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
PDXDC1
Synonyms (NCBI Gene) Gene synonyms aliases
LP8165
Chromosome Chromosome number
16
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
16p13.11
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT016276 hsa-miR-193b-3p Proteomics 21512034
MIRT046621 hsa-miR-222-3p CLASH 23622248
MIRT040072 hsa-miR-615-3p CLASH 23622248
MIRT040072 hsa-miR-615-3p CLASH 23622248
MIRT1223473 hsa-miR-1197 CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005794 Component Golgi apparatus IDA
GO:0016829 Function Lyase activity IEA
GO:0016830 Function Carbon-carbon lyase activity IEA
GO:0016831 Function Carboxy-lyase activity IEA
GO:0019752 Process Carboxylic acid metabolic process IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
614244 28995 ENSG00000179889
Protein
UniProt ID Q6P996
Protein name Pyridoxal-dependent decarboxylase domain-containing protein 1 (EC 4.1.1.-)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00282 Pyridoxal_deC 167 318 Pyridoxal-dependent decarboxylase conserved domain Domain
Sequence
MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
PWLGLPAVPAVTLYKHDD
PALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
VEGPESLR
Sequence length 788
Interactions View interactions
<
Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Diabetes Type 2 diabetes N/A N/A GWAS
Insomnia Insomnia N/A N/A GWAS
Metabolic Syndrome Metabolic syndrome N/A N/A GWAS
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Brain Neoplasms Associate 32644145
Glioblastoma Associate 32644145
Glioma Associate 28339748
Hearing Loss Associate 25528277
Neoplasms Associate 33199044