Gene Gene information from NCBI Gene database.
Entrez ID 23042
Gene name Pyridoxal dependent decarboxylase domain containing 1
Gene symbol PDXDC1
Synonyms (NCBI Gene)
LP8165
Chromosome 16
Chromosome location 16p13.11
miRNA miRNA information provided by mirtarbase database.
489
miRTarBase ID miRNA Experiments Reference
MIRT016276 hsa-miR-193b-3p Proteomics 21512034
MIRT046621 hsa-miR-222-3p CLASH 23622248
MIRT040072 hsa-miR-615-3p CLASH 23622248
MIRT040072 hsa-miR-615-3p CLASH 23622248
MIRT1223473 hsa-miR-1197 CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
8
GO ID Ontology Definition Evidence Reference
GO:0005794 Component Golgi apparatus IDA
GO:0016829 Function Lyase activity IEA
GO:0016830 Function Carbon-carbon lyase activity IEA
GO:0016831 Function Carboxy-lyase activity IEA
GO:0019752 Process Carboxylic acid metabolic process IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
614244 28995 ENSG00000179889
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q6P996
Protein name Pyridoxal-dependent decarboxylase domain-containing protein 1 (EC 4.1.1.-)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00282 Pyridoxal_deC 167 318 Pyridoxal-dependent decarboxylase conserved domain Domain
Sequence
MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
PWLGLPAVPAVTLYKHDD
PALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
VEGPESLR
Sequence length 788
Interactions View interactions
Associated diseases Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
11
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession
PDXDC1-related disorder Likely benign; Benign rs148061029, rs761085473, rs747080202, rs3198697, rs756591425, rs757982126, rs77031093, rs7200543, rs35811052, rs117719642, rs140715398 RCV003929069
RCV003981588
RCV003904084
RCV003984503
RCV003941762
RCV003941505
RCV003937022
RCV003981998
RCV003976356
RCV003972183
RCV003928560
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References
Brain Neoplasms Associate 32644145
Glioblastoma Associate 32644145
Glioma Associate 28339748
Hearing Loss Associate 25528277
Neoplasms Associate 33199044