Gene Gene information from NCBI Gene database.
Entrez ID 23012
Gene name Serine/threonine kinase 38 like
Gene symbol STK38L
Synonyms (NCBI Gene)
NDR2
Chromosome 12
Chromosome location 12p11.23
miRNA miRNA information provided by mirtarbase database.
401
miRTarBase ID miRNA Experiments Reference
MIRT019964 hsa-miR-375 Microarray 20215506
MIRT022750 hsa-miR-124-3p Microarray 18668037
MIRT045849 hsa-miR-130a-3p CLASH 23622248
MIRT063948 hsa-miR-205-5p HITS-CLIP 22473208
MIRT063948 hsa-miR-205-5p HITS-CLIP 22473208
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
33
GO ID Ontology Definition Evidence Reference
GO:0000166 Function Nucleotide binding IEA
GO:0000287 Function Magnesium ion binding IDA 15067004
GO:0000287 Function Magnesium ion binding IEA
GO:0003779 Function Actin binding IEA
GO:0004672 Function Protein kinase activity IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
615836 17848 ENSG00000211455
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9Y2H1
Protein name Serine/threonine-protein kinase 38-like (EC 2.7.11.1) (NDR2 protein kinase) (Nuclear Dbf2-related kinase 2)
Protein function Involved in the regulation of structural processes in differentiating and mature neuronal cells.
PDB 5XQZ
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00069 Pkinase 90 383 Protein kinase domain Domain
PF00433 Pkinase_C 402 443 Protein kinase C terminal domain Family
Tissue specificity TISSUE SPECIFICITY: Ubiquitously expressed with highest levels observed in the thymus. {ECO:0000269|PubMed:15067004}.
Sequence
Sequence length 464
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
12
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
CENTRAL NERVOUS SYSTEM CANCER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Cholangiocarcinoma Benign ClinVar
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
DEMENTIA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Familial cancer of breast Likely benign ClinVar
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References Evidence Score
Developmental Disabilities Associate 37563198
★☆☆☆☆
Found in Text Mining only
Kallmann Syndrome Associate 37563198
★☆☆☆☆
Found in Text Mining only
Microsatellite Instability Associate 30108113
★☆☆☆☆
Found in Text Mining only
Ovarian Neoplasms Associate 30392041
★☆☆☆☆
Found in Text Mining only