RAB21 (RAB21, member RAS oncogene family)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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23011 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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RAB21, member RAS oncogene family |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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RAB21 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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Chromosome
Chromosome number
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12 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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12q21.1 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequ |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q9UL25 | ||||||||||
Protein name | Ras-related protein Rab-21 (EC 3.6.5.2) | ||||||||||
Protein function | The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to r | ||||||||||
PDB | 1YZT , 1YZU , 1Z08 , 1Z0I , 2OT3 | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Widely expressed. In jejunal tissue, predominantly expressed in the apical region of the epithelial cell layer of the villi, weak expression, if any, in the crypt epithelium. Capillary endothelium and some cell types in the lamina prop | ||||||||||
Sequence |
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Sequence length | 225 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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