Gene Gene information from NCBI Gene database.
Entrez ID 23008
Gene name Kelch domain containing 10
Gene symbol KLHDC10
Synonyms (NCBI Gene)
PNAS-138slim
Chromosome 7
Chromosome location 7q32.2
miRNA miRNA information provided by mirtarbase database.
809
miRTarBase ID miRNA Experiments Reference
MIRT040901 hsa-miR-18a-3p CLASH 23622248
MIRT723202 hsa-miR-3121-3p HITS-CLIP 19536157
MIRT723201 hsa-miR-5197-3p HITS-CLIP 19536157
MIRT402088 hsa-miR-7705 HITS-CLIP 19536157
MIRT392663 hsa-miR-4696 HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
11
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 20562859, 25036637
GO:0005634 Component Nucleus IEA
GO:0005654 Component Nucleoplasm IDA
GO:0005737 Component Cytoplasm IDA 23102700
GO:0005737 Component Cytoplasm IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
615152 22194 ENSG00000128607
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q6PID8
Protein name Kelch domain-containing protein 10
Protein function Substrate-recognition component of a Cul2-RING (CRL2) E3 ubiquitin-protein ligase complex of the DesCEND (destruction via C-end degrons) pathway, which recognizes a C-degron located at the extreme C-terminus of target proteins, leading to their
PDB 9D8P
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13964 Kelch_6 91 153 Repeat
PF13418 Kelch_4 205 253 Repeat
PF01344 Kelch_1 259 306 Kelch motif Repeat
PF01344 Kelch_1 315 360 Kelch motif Repeat
Sequence
MSAAQGWDRNRRRGGGAAGAGGGGSGAGGGSGGSGGRGTGQLNRFVQLSGRPHLPGKKKI
RWDPVRRRFIQSCPIIRIPNRFLRGHRPPPARSGHRCVADNTNLYVFGGYNPDYDESGGP
DNEDYPLFRELWRYHFATGVWHQMGTDGYMPRE
LASMSLVLHGNNLLVFGGTGIPFGESN
GNDVHVCNVKYKRWALLSCRGKKPSRIYGQAMAIINGSLYVFGGTTGYIYSTDLHKLDLN
TREWTQLKPNNLS
CDLPEERYRHEIAHDGQRIYILGGGTSWTAYSLNKIHAYNLETNAWE
EIATKP
HEKIGFPAARRCHSCVQIKNDVFICGGYNGEVILGDIWKLNLQTFQWVKLPATM
PEPVYFHCAAVTPAGCMYIHGGVVNIHENKRTGSLFKIWLVVPSLLELAWEKLLAAFPNL
ANLSRTQLLHLGLTQGLIERLK
Sequence length 442
Interactions View interactions