SLC4A1AP (solute carrier family 4 member 1 adaptor protein)

Gene

• Entrez ID: 22950
• Gene name: Solute carrier family 4 member 1 adaptor protein
• Gene symbol: SLC4A1AP
• Synonyms (NCBI Gene): HLC3
• Chromosome: 2
• Chromosome location: 2p23.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT019988	hsa-miR-375	Microarray	20215506
MIRT032022	hsa-miR-16-5p	Proteomics	18668040
MIRT045177	hsa-miR-186-5p	CLASH	23622248
MIRT710811	hsa-miR-583	HITS-CLIP	19536157
MIRT710810	hsa-miR-6759-3p	HITS-CLIP	19536157
MIRT710809	hsa-miR-377-5p	HITS-CLIP	19536157
MIRT710808	hsa-miR-6086	HITS-CLIP	19536157
MIRT710807	hsa-miR-7973	HITS-CLIP	19536157
MIRT710806	hsa-miR-6808-3p	HITS-CLIP	19536157
MIRT710805	hsa-miR-758-3p	HITS-CLIP	19536157
MIRT710811	hsa-miR-583	HITS-CLIP	19536157
MIRT710810	hsa-miR-6759-3p	HITS-CLIP	19536157
MIRT710809	hsa-miR-377-5p	HITS-CLIP	19536157
MIRT710808	hsa-miR-6086	HITS-CLIP	19536157
MIRT710807	hsa-miR-7973	HITS-CLIP	19536157
MIRT710806	hsa-miR-6808-3p	HITS-CLIP	19536157
MIRT710805	hsa-miR-758-3p	HITS-CLIP	19536157
MIRT710811	hsa-miR-583	HITS-CLIP	19536157
MIRT710810	hsa-miR-6759-3p	HITS-CLIP	19536157
MIRT710809	hsa-miR-377-5p	HITS-CLIP	19536157
MIRT710808	hsa-miR-6086	HITS-CLIP	19536157
MIRT710807	hsa-miR-7973	HITS-CLIP	19536157
MIRT710806	hsa-miR-6808-3p	HITS-CLIP	19536157
MIRT710805	hsa-miR-758-3p	HITS-CLIP	19536157
MIRT710811	hsa-miR-583	HITS-CLIP	19536157
MIRT710810	hsa-miR-6759-3p	HITS-CLIP	19536157
MIRT710809	hsa-miR-377-5p	HITS-CLIP	19536157
MIRT710808	hsa-miR-6086	HITS-CLIP	19536157
MIRT710807	hsa-miR-7973	HITS-CLIP	19536157
MIRT710806	hsa-miR-6808-3p	HITS-CLIP	19536157
MIRT710805	hsa-miR-758-3p	HITS-CLIP	19536157
MIRT2108303	hsa-miR-3122	CLIP-seq
MIRT2108304	hsa-miR-3913-5p	CLIP-seq
MIRT2108305	hsa-miR-4320	CLIP-seq
MIRT2108306	hsa-miR-4476	CLIP-seq
MIRT2108307	hsa-miR-450b-3p	CLIP-seq
MIRT2108308	hsa-miR-4786-3p	CLIP-seq
MIRT2108309	hsa-miR-513a-3p	CLIP-seq
MIRT2108310	hsa-miR-577	CLIP-seq
MIRT2108311	hsa-miR-580	CLIP-seq
MIRT2108312	hsa-miR-624	CLIP-seq
MIRT2108313	hsa-miR-651	CLIP-seq
MIRT2108314	hsa-miR-671-5p	CLIP-seq
MIRT2108315	hsa-miR-769-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003729	Function	MRNA binding	IBA
GO:0005515	Function	Protein binding	IPI	17553790, 25416956
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IEA
GO:0005886	Component	Plasma membrane	IDA

Other IDs

• MIM: 602655
• HGNC: 13813
• e!Ensembl: ENSG00000163798

Protein

• UniProt ID: Q9BWU0
• Protein name: Kanadaptin (Human lung cancer oncogene 3 protein) (HLC-3) (Kidney anion exchanger adapter protein) (Solute carrier family 4 anion exchanger member 1 adapter protein)
• PDB: 4H87
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00498	FHA	189 → 266	FHA domain	Family

• Tissue specificity: TISSUE SPECIFICITY: Ubiquitously expressed. {ECO:0000269|PubMed:15764369}.
• Sequence:

  MLAPLRNAPGREGATSPSPPTDATGSLGEWDVDRNVKTEGWVSKERISKLHRLRMADILS
  QSETLASQDLSGDFKKPALPVSPAARSKAPASSSSNPEEVQKEGPTALQDSNSGEPDIPP
  PQPDCGDFRSLQEEQSRPPTAVSSPGGPARAPPYQEPPWGGPATAPYSLETLKGGTILGT
  RSLKGTSYCLFGRLSGCDVCLEHPSVSRYHAVLQHRASGPDGECDSNGPGFYLYDLGSTH
  GTFLNKTRIPPRTYCRVHVGHVVRFGGSTRLFILQGPEEDREAESELTVTQLKELRKQQQ
  ILLEKKMLGEDSDEEEEMDTSERKINAGSQDDEMGCTWGMGEDAVEDDAEENPIVLEFQQ
  EREAFYIKDPKKALQGFFDREGEELEYEFDEQGHSTWLCRVRLPVDDSTGKQLVAEAIHS
  GKKKEAMIQCSLEACRILDTLGLLRQEAVSRKRKAKNWEDEDFYDSDDDTFLDRTGLIEK
  KRLNRMKKAGKIDEKPETFESLVAKLNDAERELSEISERLKASSQVLSESPSQDSLDAFM
  SEMKSGSTLDGVSRKKLHLRTFELRKEQQRLKGLIKIVKPAEIPELKKTETQTTGAENKA
  KKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKE
  KEEHEKKKLEDGSLSRPQPEIEPEAAVQEMRPPTDLTHFKETQTHENMSQLSEEEQNKDY
  QDCSKTTSLCAGPSASKNEYEKSRGELKKKKTPGPGKLPPTLSSKYPEDDPDYCVWVPPE
  GQSGDGRTHLNDKYGY

• Sequence length: 796

Associated diseases

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
EBV-positive nodal T- and NK-cell lymphoma	Likely benign	rs1418769633	RCV004557959