Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	22891
Gene name Gene Name - the full gene name approved by the HGNC.	Zinc finger protein 365
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ZNF365
Synonyms (NCBI Gene) Gene synonyms aliases	Su48, UAN, ZNF365D
Chromosome Chromosome number	10
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	10q21.2
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a zinc finger protein that may play a role in the repair of DNA damage and maintenance of genome stability. The N-terminal C2H2 zinc finger motif is required to form a protein complex with PARP1 and MRE11, which are known to be involved

Show/Hide all(139)

miRTarBase ID	miRNA	Experiments	Reference
MIRT016433	hsa-miR-193b-3p	Microarray	20304954
MIRT025758	hsa-miR-7-5p	Microarray	17612493
MIRT437691	hsa-miR-223-3p	Microarray, qRT-PCR	22815788
MIRT1523164	hsa-miR-1299	CLIP-seq
MIRT1523165	hsa-miR-3182	CLIP-seq
MIRT1523166	hsa-miR-3686	CLIP-seq
MIRT1523167	hsa-miR-875-3p	CLIP-seq
MIRT1523168	hsa-miR-1233	CLIP-seq
MIRT1523169	hsa-miR-1266	CLIP-seq
MIRT1523170	hsa-miR-129-3p	CLIP-seq
MIRT1523171	hsa-miR-1294	CLIP-seq
MIRT1523172	hsa-miR-1304	CLIP-seq
MIRT1523173	hsa-miR-132	CLIP-seq
MIRT1523174	hsa-miR-1343	CLIP-seq
MIRT1523175	hsa-miR-140-5p	CLIP-seq
MIRT1523176	hsa-miR-186	CLIP-seq
MIRT1523177	hsa-miR-200b	CLIP-seq
MIRT1523178	hsa-miR-200c	CLIP-seq
MIRT1523179	hsa-miR-21	CLIP-seq
MIRT1523180	hsa-miR-212	CLIP-seq
MIRT1523181	hsa-miR-3133	CLIP-seq
MIRT1523182	hsa-miR-3143	CLIP-seq
MIRT1523183	hsa-miR-3156-5p	CLIP-seq
MIRT1523184	hsa-miR-3165	CLIP-seq
MIRT1523185	hsa-miR-323-5p	CLIP-seq
MIRT1523186	hsa-miR-3646	CLIP-seq
MIRT1523187	hsa-miR-3650	CLIP-seq
MIRT1523188	hsa-miR-3662	CLIP-seq
MIRT1523189	hsa-miR-3664-3p	CLIP-seq
MIRT1523190	hsa-miR-3682-5p	CLIP-seq
MIRT1523191	hsa-miR-3688-5p	CLIP-seq
MIRT1523192	hsa-miR-374c	CLIP-seq
MIRT1523193	hsa-miR-3919	CLIP-seq
MIRT1523194	hsa-miR-409-5p	CLIP-seq
MIRT1523195	hsa-miR-4269	CLIP-seq
MIRT1523196	hsa-miR-429	CLIP-seq
MIRT1523197	hsa-miR-4303	CLIP-seq
MIRT1523198	hsa-miR-4316	CLIP-seq
MIRT1523199	hsa-miR-4423-5p	CLIP-seq
MIRT1523200	hsa-miR-4428	CLIP-seq
MIRT1523201	hsa-miR-4455	CLIP-seq
MIRT1523202	hsa-miR-4481	CLIP-seq
MIRT1523203	hsa-miR-4514	CLIP-seq
MIRT1523204	hsa-miR-4518	CLIP-seq
MIRT1523205	hsa-miR-4668-5p	CLIP-seq
MIRT1523206	hsa-miR-4677-3p	CLIP-seq
MIRT1523207	hsa-miR-4679	CLIP-seq
MIRT1523208	hsa-miR-4682	CLIP-seq
MIRT1523209	hsa-miR-4692	CLIP-seq
MIRT1523210	hsa-miR-4711-3p	CLIP-seq
MIRT1523211	hsa-miR-4742-5p	CLIP-seq
MIRT1523212	hsa-miR-4745-5p	CLIP-seq
MIRT1523213	hsa-miR-4756-3p	CLIP-seq
MIRT1523214	hsa-miR-4758-5p	CLIP-seq
MIRT1523215	hsa-miR-4790-3p	CLIP-seq
MIRT1523216	hsa-miR-509-3p	CLIP-seq
MIRT1523217	hsa-miR-543	CLIP-seq
MIRT1523218	hsa-miR-555	CLIP-seq
MIRT1523219	hsa-miR-590-5p	CLIP-seq
MIRT1523220	hsa-miR-605	CLIP-seq
MIRT1523221	hsa-miR-609	CLIP-seq
MIRT1523222	hsa-miR-640	CLIP-seq
MIRT1523223	hsa-miR-655	CLIP-seq
MIRT1523224	hsa-miR-876-3p	CLIP-seq
MIRT1523225	hsa-miR-891b	CLIP-seq
MIRT1523226	hsa-miR-944	CLIP-seq
MIRT1523166	hsa-miR-3686	CLIP-seq
MIRT2158089	hsa-miR-4752	CLIP-seq
MIRT2377671	hsa-miR-15a	CLIP-seq
MIRT2377672	hsa-miR-15b	CLIP-seq
MIRT2377673	hsa-miR-16	CLIP-seq
MIRT2377674	hsa-miR-195	CLIP-seq
MIRT2377675	hsa-miR-214	CLIP-seq
MIRT2377676	hsa-miR-2681	CLIP-seq
MIRT2377677	hsa-miR-298	CLIP-seq
MIRT2377678	hsa-miR-3609	CLIP-seq
MIRT2377679	hsa-miR-3617	CLIP-seq
MIRT2377680	hsa-miR-3619-5p	CLIP-seq
MIRT2377681	hsa-miR-3973	CLIP-seq
MIRT2377682	hsa-miR-424	CLIP-seq
MIRT2377683	hsa-miR-4459	CLIP-seq
MIRT2377684	hsa-miR-4527	CLIP-seq
MIRT2377685	hsa-miR-4641	CLIP-seq
MIRT2377686	hsa-miR-4699-5p	CLIP-seq
MIRT2377687	hsa-miR-4722-5p	CLIP-seq
MIRT2377688	hsa-miR-497	CLIP-seq
MIRT2377689	hsa-miR-510	CLIP-seq
MIRT2377690	hsa-miR-512-5p	CLIP-seq
MIRT2377691	hsa-miR-520g	CLIP-seq
MIRT2377692	hsa-miR-520h	CLIP-seq
MIRT2377693	hsa-miR-548ah	CLIP-seq
MIRT2377694	hsa-miR-641	CLIP-seq
MIRT2377695	hsa-miR-761	CLIP-seq
MIRT2441820	hsa-miR-3622a-3p	CLIP-seq
MIRT2441821	hsa-miR-3622b-3p	CLIP-seq
MIRT2441822	hsa-miR-5096	CLIP-seq
MIRT2441823	hsa-miR-511	CLIP-seq
MIRT2670000	hsa-miR-1193	CLIP-seq
MIRT2670001	hsa-miR-1273	CLIP-seq
MIRT2670002	hsa-miR-193a-3p	CLIP-seq
MIRT2670003	hsa-miR-193b	CLIP-seq
MIRT2670004	hsa-miR-2115	CLIP-seq
MIRT2670005	hsa-miR-2392	CLIP-seq
MIRT2670006	hsa-miR-3117-5p	CLIP-seq
MIRT2670007	hsa-miR-3158-3p	CLIP-seq
MIRT2670008	hsa-miR-4496	CLIP-seq
MIRT2670009	hsa-miR-455-3p	CLIP-seq
MIRT2670010	hsa-miR-4743	CLIP-seq
MIRT2670011	hsa-miR-501-3p	CLIP-seq
MIRT2670012	hsa-miR-502-3p	CLIP-seq
MIRT2670013	hsa-miR-516a-3p	CLIP-seq
MIRT2670014	hsa-miR-520f	CLIP-seq
MIRT2670015	hsa-miR-665	CLIP-seq
MIRT2670016	hsa-miR-767-5p	CLIP-seq
MIRT2670000	hsa-miR-1193	CLIP-seq
MIRT2670001	hsa-miR-1273	CLIP-seq
MIRT2670002	hsa-miR-193a-3p	CLIP-seq
MIRT2670003	hsa-miR-193b	CLIP-seq
MIRT2670004	hsa-miR-2115	CLIP-seq
MIRT2670005	hsa-miR-2392	CLIP-seq
MIRT2670006	hsa-miR-3117-5p	CLIP-seq
MIRT2670007	hsa-miR-3158-3p	CLIP-seq
MIRT2695976	hsa-miR-3173-3p	CLIP-seq
MIRT2695977	hsa-miR-3612	CLIP-seq
MIRT1523200	hsa-miR-4428	CLIP-seq
MIRT2670008	hsa-miR-4496	CLIP-seq
MIRT2695978	hsa-miR-4521	CLIP-seq
MIRT2695979	hsa-miR-4695-5p	CLIP-seq
MIRT2670010	hsa-miR-4743	CLIP-seq
MIRT2670011	hsa-miR-501-3p	CLIP-seq
MIRT2670012	hsa-miR-502-3p	CLIP-seq
MIRT2695980	hsa-miR-513a-3p	CLIP-seq
MIRT2670013	hsa-miR-516a-3p	CLIP-seq
MIRT2670014	hsa-miR-520f	CLIP-seq
MIRT2695981	hsa-miR-593	CLIP-seq
MIRT2695982	hsa-miR-650	CLIP-seq
MIRT2695983	hsa-miR-654-3p	CLIP-seq
MIRT2670015	hsa-miR-665	CLIP-seq
MIRT2670016	hsa-miR-767-5p	CLIP-seq

Show/Hide all(29)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000281	Process	Mitotic cytokinesis	IMP	16617106
GO:0000723	Process	Telomere maintenance	IBA
GO:0000723	Process	Telomere maintenance	IEA
GO:0000723	Process	Telomere maintenance	IMP	23776040
GO:0005515	Function	Protein binding	IPI	16682949, 17389905, 23966166
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IDA	16617106
GO:0005813	Component	Centrosome	IEA
GO:0005856	Component	Cytoskeleton	IEA
GO:0007399	Process	Nervous system development	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0010569	Process	Regulation of double-strand break repair via homologous recombination	IBA
GO:0010569	Process	Regulation of double-strand break repair via homologous recombination	IMP	23966166
GO:0010975	Process	Regulation of neuron projection development	IBA
GO:0010977	Process	Negative regulation of neuron projection development	IDA	17389905
GO:0021687	Process	Cerebellar molecular layer morphogenesis	IEA
GO:0021687	Process	Cerebellar molecular layer morphogenesis	ISS
GO:0033566	Process	Gamma-tubulin complex localization	IMP	16617106
GO:0042802	Function	Identical protein binding	IPI	16617106
GO:0042803	Function	Protein homodimerization activity	IDA	16617106
GO:0046872	Function	Metal ion binding	IEA
GO:0048714	Process	Positive regulation of oligodendrocyte differentiation	IEA
GO:0048714	Process	Positive regulation of oligodendrocyte differentiation	ISS
GO:0060997	Process	Dendritic spine morphogenesis	IEA
GO:0060997	Process	Dendritic spine morphogenesis	ISS
GO:0110026	Process	Regulation of DNA strand resection involved in replication fork processing	IBA
GO:0110026	Process	Regulation of DNA strand resection involved in replication fork processing	IMP	23966166
GO:0140059	Process	Dendrite arborization	IEA
GO:0140059	Process	Dendrite arborization	ISS

MIM	HGNC	e!Ensembl
607818	18194	ENSG00000138311

Protein

UniProt ID

Q70YC4

Protein name

Talanin

Protein function

May play a role in uric acid excretion.

Family and domains

Tissue specificity

TISSUE SPECIFICITY: Isoform 4 is expressed in placenta, lung, kidney and pancreas. {ECO:0000269|PubMed:12740763}.

Sequence

MSALGQITITVSRCWNTERNQTDKNPCLHGAYLQLRETVKNKSTHLKKPLMKQAPPWKDH
LTFQPLHPAERKTQVWRWQSGNSSDLETTSSASPWPTGSNRDVVLNTLAESCCGLSELIT
APPYAGVSIQGFSQIWVLFPFCGGTFHHNEKDVLGLQDFERESVSTSQSRNISLLTLGQL
QNCVIGKLTIIDLLTEHLLGVRHGVICFPWGLPSSS

Sequence length

216

UniProt ID

Q70YC5

Protein name

Protein ZNF365 (DISC1-binding zinc-finger protein) (Protein su48)

Protein function

Involved in the regulation of neurogenesis. Negatively regulates neurite outgrowth (PubMed:17389905). Involved in the morphogenesis of basket cells in the somatosensory cortex during embryogenesis. Involved in the positive regulation of oligoden

Family and domains

Tissue specificity

TISSUE SPECIFICITY: Isoform 1 is expressed in brain. Isoform 2 is expressed in placenta and at low level in lung and liver. Isoform 3 is expressed in kidney and pancreas. Isoform 1 is expressed exclusively in brain (PubMed:17389905). {ECO:0000269|PubMed:1

Sequence

MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLT
KCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAE
RPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRI
DKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESE
EELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGF
VRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPA
KAIHEQAESSRDLCRPPKKGELLGFGRKGNIRPKMAKKKPTAIVNII

Sequence length

407

Interactions

View interactions

Show/Hide Unknown Diseases (2)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Breast cancer	Breast cancer (estrogen-receptor negative), Breast cancer	N/A	N/A	GWAS
Schizophrenia	Schizophrenia	N/A	N/A	GWAS

Show/Hide Text Mining Associations (16)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Aneuploidy	Inhibit	23776040
Breast Carcinoma In Situ	Associate	24743323
Breast Neoplasms	Associate	21060860, 21908515, 22348646, 22351618, 22747683, 24528085, 24722754, 24743323, 25329322, 25862352, 26036842, 26073781, 27863437, 38094285
Colitis Ulcerative	Associate	21818367, 21830272
Colonic Diseases	Associate	21830272
Crohn Disease	Associate	21257989, 21818367, 21830272, 25489960, 28300425, 30500874
Death Sudden Cardiac	Associate	23593153
Disease	Associate	21853134
Inflammation	Associate	28300425
Narcolepsy	Associate	24204295
Neoplasms	Associate	23776040
Ovarian Neoplasms	Associate	22351618
Renal Insufficiency	Inhibit	23776040
Telomeric 22q13 Monosomy Syndrome	Associate	23776040
Triple Negative Breast Neoplasms	Associate	27863437
Uveomeningoencephalitic Syndrome	Associate	32437414

ZNF365 (zinc finger protein 365)