Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	2289
Gene name	FKBP prolyl isomerase 5
Gene symbol	FKBP5
Synonyms (NCBI Gene)	AIG6FKBP51FKBP54P54PPIasePtg-10
Chromosome	6
Chromosome location	6p21.31
Summary	The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds

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SNP ID	Visualize variation	Clinical significance	Consequence
rs4713916	A>C,G,T	Drug-response	Genic upstream transcript variant, intron variant

447

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miRTarBase ID	miRNA	Experiments	Reference
MIRT030843	hsa-miR-21-5p	Microarray	18591254
MIRT050456	hsa-miR-22-3p	CLASH	23622248
MIRT043776	hsa-miR-328-3p	CLASH	23622248
MIRT038745	hsa-miR-93-3p	CLASH	23622248
MIRT437605	hsa-miR-100-5p	FACSLuciferase reporter assayqRT-PCRWestern blot	24030073
MIRT437605	hsa-miR-100-5p	FACSLuciferase reporter assayqRT-PCRWestern blot	24030073
MIRT437608	hsa-miR-99a-5p	FACSLuciferase reporter assayqRT-PCRWestern blot	24030073
MIRT437608	hsa-miR-99a-5p	FACSLuciferase reporter assayqRT-PCRWestern blot	24030073
MIRT668337	hsa-miR-4485-5p	HITS-CLIP	23824327
MIRT668336	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT668335	hsa-miR-939-3p	HITS-CLIP	23824327
MIRT668334	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT668333	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT668332	hsa-miR-1281	HITS-CLIP	23824327
MIRT668331	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT668330	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT668329	hsa-miR-23a-5p	HITS-CLIP	23824327
MIRT668328	hsa-miR-23b-5p	HITS-CLIP	23824327
MIRT668327	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT668326	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT537342	hsa-miR-8080	PAR-CLIP	22012620
MIRT537340	hsa-miR-6816-3p	PAR-CLIP	22012620
MIRT537341	hsa-miR-3169	PAR-CLIP	22012620
MIRT537339	hsa-miR-4272	PAR-CLIP	22012620
MIRT537338	hsa-miR-4740-5p	PAR-CLIP	22012620
MIRT537337	hsa-miR-4666a-5p	PAR-CLIP	22012620
MIRT514720	hsa-miR-512-5p	PAR-CLIP	23446348
MIRT514719	hsa-miR-510-5p	PAR-CLIP	23446348
MIRT514718	hsa-miR-5690	PAR-CLIP	23446348
MIRT514717	hsa-miR-3664-3p	PAR-CLIP	23446348
MIRT514716	hsa-miR-3166	PAR-CLIP	23446348
MIRT514715	hsa-miR-7977	PAR-CLIP	23446348
MIRT452010	hsa-miR-4779	PAR-CLIP	23592263
MIRT452011	hsa-miR-6760-5p	PAR-CLIP	23592263
MIRT452009	hsa-miR-1321	PAR-CLIP	23592263
MIRT452008	hsa-miR-4739	PAR-CLIP	23592263
MIRT452007	hsa-miR-4756-5p	PAR-CLIP	23592263
MIRT452006	hsa-miR-4270	PAR-CLIP	23592263
MIRT452005	hsa-miR-4441	PAR-CLIP	23592263
MIRT452004	hsa-miR-6754-5p	PAR-CLIP	23592263
MIRT452003	hsa-miR-539-5p	PAR-CLIP	23592263
MIRT452002	hsa-miR-4419a	PAR-CLIP	23592263
MIRT452001	hsa-miR-4510	PAR-CLIP	23592263
MIRT452000	hsa-miR-6127	PAR-CLIP	23592263
MIRT451999	hsa-miR-6129	PAR-CLIP	23592263
MIRT451998	hsa-miR-6130	PAR-CLIP	23592263
MIRT451996	hsa-miR-6133	PAR-CLIP	23592263
MIRT451997	hsa-miR-765	PAR-CLIP	23592263
MIRT451995	hsa-miR-1249-5p	PAR-CLIP	23592263
MIRT451994	hsa-miR-6797-5p	PAR-CLIP	23592263
MIRT451993	hsa-miR-6878-5p	PAR-CLIP	23592263
MIRT451992	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT451991	hsa-miR-302c-5p	PAR-CLIP	23592263
MIRT451990	hsa-miR-200b-3p	PAR-CLIP	23592263
MIRT451989	hsa-miR-200c-3p	PAR-CLIP	23592263
MIRT451988	hsa-miR-429	PAR-CLIP	23592263
MIRT451987	hsa-miR-3654	PAR-CLIP	23592263
MIRT451986	hsa-miR-1243	PAR-CLIP	23592263
MIRT451985	hsa-miR-1910-3p	PAR-CLIP	23592263
MIRT451984	hsa-miR-6511a-5p	PAR-CLIP	23592263
MIRT451983	hsa-miR-4257	PAR-CLIP	23592263
MIRT451982	hsa-miR-5186	PAR-CLIP	23592263
MIRT451981	hsa-miR-4537	PAR-CLIP	23592263
MIRT451980	hsa-miR-1827	PAR-CLIP	23592263
MIRT451979	hsa-miR-377-5p	PAR-CLIP	23592263
MIRT451978	hsa-miR-6086	PAR-CLIP	23592263
MIRT451977	hsa-miR-2467-3p	PAR-CLIP	23592263
MIRT451976	hsa-miR-6499-3p	PAR-CLIP	23592263
MIRT451975	hsa-miR-3612	PAR-CLIP	23592263
MIRT451974	hsa-miR-650	PAR-CLIP	23592263
MIRT451973	hsa-miR-455-3p	PAR-CLIP	23592263
MIRT451972	hsa-miR-4443	PAR-CLIP	23592263
MIRT451971	hsa-miR-550b-2-5p	PAR-CLIP	23592263
MIRT451970	hsa-miR-6516-5p	PAR-CLIP	23592263
MIRT731709	hsa-miR-511-5p	Luciferase reporter assayqRT-PCR	27334923
MIRT731709	hsa-miR-511-5p	Luciferase reporter assayqRT-PCR	27334923
MIRT668337	hsa-miR-4485-5p	HITS-CLIP	23824327
MIRT668336	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT668335	hsa-miR-939-3p	HITS-CLIP	23824327
MIRT668334	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT668333	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT668332	hsa-miR-1281	HITS-CLIP	23824327
MIRT668331	hsa-miR-6791-3p	HITS-CLIP	23824327
MIRT668330	hsa-miR-6829-3p	HITS-CLIP	23824327
MIRT668329	hsa-miR-23a-5p	HITS-CLIP	23824327
MIRT668328	hsa-miR-23b-5p	HITS-CLIP	23824327
MIRT668327	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT668326	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT537342	hsa-miR-8080	PAR-CLIP	22012620
MIRT537340	hsa-miR-6816-3p	PAR-CLIP	22012620
MIRT537341	hsa-miR-3169	PAR-CLIP	22012620
MIRT537339	hsa-miR-4272	PAR-CLIP	22012620
MIRT537338	hsa-miR-4740-5p	PAR-CLIP	22012620
MIRT537337	hsa-miR-4666a-5p	PAR-CLIP	22012620
MIRT514720	hsa-miR-512-5p	PAR-CLIP	23446348
MIRT514719	hsa-miR-510-5p	PAR-CLIP	23446348
MIRT514718	hsa-miR-5690	PAR-CLIP	23446348
MIRT514717	hsa-miR-3664-3p	PAR-CLIP	23446348
MIRT514716	hsa-miR-3166	PAR-CLIP	23446348
MIRT514715	hsa-miR-7977	PAR-CLIP	23446348
MIRT452010	hsa-miR-4779	PAR-CLIP	23592263
MIRT452011	hsa-miR-6760-5p	PAR-CLIP	23592263
MIRT452009	hsa-miR-1321	PAR-CLIP	23592263
MIRT452008	hsa-miR-4739	PAR-CLIP	23592263
MIRT452007	hsa-miR-4756-5p	PAR-CLIP	23592263
MIRT452006	hsa-miR-4270	PAR-CLIP	23592263
MIRT452005	hsa-miR-4441	PAR-CLIP	23592263
MIRT452004	hsa-miR-6754-5p	PAR-CLIP	23592263
MIRT452003	hsa-miR-539-5p	PAR-CLIP	23592263
MIRT452002	hsa-miR-4419a	PAR-CLIP	23592263
MIRT452001	hsa-miR-4510	PAR-CLIP	23592263
MIRT452000	hsa-miR-6127	PAR-CLIP	23592263
MIRT451999	hsa-miR-6129	PAR-CLIP	23592263
MIRT451998	hsa-miR-6130	PAR-CLIP	23592263
MIRT451996	hsa-miR-6133	PAR-CLIP	23592263
MIRT451997	hsa-miR-765	PAR-CLIP	23592263
MIRT451995	hsa-miR-1249-5p	PAR-CLIP	23592263
MIRT451994	hsa-miR-6797-5p	PAR-CLIP	23592263
MIRT451993	hsa-miR-6878-5p	PAR-CLIP	23592263
MIRT451992	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT451991	hsa-miR-302c-5p	PAR-CLIP	23592263
MIRT451990	hsa-miR-200b-3p	PAR-CLIP	23592263
MIRT451989	hsa-miR-200c-3p	PAR-CLIP	23592263
MIRT451988	hsa-miR-429	PAR-CLIP	23592263
MIRT451987	hsa-miR-3654	PAR-CLIP	23592263
MIRT451986	hsa-miR-1243	PAR-CLIP	23592263
MIRT451985	hsa-miR-1910-3p	PAR-CLIP	23592263
MIRT451984	hsa-miR-6511a-5p	PAR-CLIP	23592263
MIRT451983	hsa-miR-4257	PAR-CLIP	23592263
MIRT451982	hsa-miR-5186	PAR-CLIP	23592263
MIRT451981	hsa-miR-4537	PAR-CLIP	23592263
MIRT451980	hsa-miR-1827	PAR-CLIP	23592263
MIRT451979	hsa-miR-377-5p	PAR-CLIP	23592263
MIRT451978	hsa-miR-6086	PAR-CLIP	23592263
MIRT451977	hsa-miR-2467-3p	PAR-CLIP	23592263
MIRT451976	hsa-miR-6499-3p	PAR-CLIP	23592263
MIRT451975	hsa-miR-3612	PAR-CLIP	23592263
MIRT451974	hsa-miR-650	PAR-CLIP	23592263
MIRT451973	hsa-miR-455-3p	PAR-CLIP	23592263
MIRT451972	hsa-miR-4443	PAR-CLIP	23592263
MIRT451971	hsa-miR-550b-2-5p	PAR-CLIP	23592263
MIRT451970	hsa-miR-6516-5p	PAR-CLIP	23592263
MIRT755358	hsa-miR-340-3p	Luciferase reporter assayWestern blottingqRT-PCR	36769373
MIRT997558	hsa-miR-1261	CLIP-seq
MIRT997559	hsa-miR-147	CLIP-seq
MIRT997560	hsa-miR-1470	CLIP-seq
MIRT997561	hsa-miR-15a	CLIP-seq
MIRT997562	hsa-miR-15b	CLIP-seq
MIRT997563	hsa-miR-16	CLIP-seq
MIRT997564	hsa-miR-1909	CLIP-seq
MIRT997565	hsa-miR-1915	CLIP-seq
MIRT997566	hsa-miR-195	CLIP-seq
MIRT997567	hsa-miR-203	CLIP-seq
MIRT997568	hsa-miR-208a	CLIP-seq
MIRT997569	hsa-miR-208b	CLIP-seq
MIRT997570	hsa-miR-2115	CLIP-seq
MIRT997571	hsa-miR-214	CLIP-seq
MIRT997572	hsa-miR-219-2-3p	CLIP-seq
MIRT997573	hsa-miR-2964a-3p	CLIP-seq
MIRT997574	hsa-miR-3117-5p	CLIP-seq
MIRT997575	hsa-miR-3140-5p	CLIP-seq
MIRT997576	hsa-miR-3150a-3p	CLIP-seq
MIRT997577	hsa-miR-3157-3p	CLIP-seq
MIRT997578	hsa-miR-3160-3p	CLIP-seq
MIRT997579	hsa-miR-3175	CLIP-seq
MIRT997580	hsa-miR-3180-5p	CLIP-seq
MIRT997581	hsa-miR-3190	CLIP-seq
MIRT997582	hsa-miR-320e	CLIP-seq
MIRT997583	hsa-miR-3529	CLIP-seq
MIRT997584	hsa-miR-361-3p	CLIP-seq
MIRT997585	hsa-miR-3619-5p	CLIP-seq
MIRT997586	hsa-miR-3658	CLIP-seq
MIRT997587	hsa-miR-375	CLIP-seq
MIRT997588	hsa-miR-376c	CLIP-seq
MIRT997589	hsa-miR-378	CLIP-seq
MIRT997590	hsa-miR-378b	CLIP-seq
MIRT997591	hsa-miR-378c	CLIP-seq
MIRT997592	hsa-miR-378d	CLIP-seq
MIRT997593	hsa-miR-378e	CLIP-seq
MIRT997594	hsa-miR-378f	CLIP-seq
MIRT997595	hsa-miR-378h	CLIP-seq
MIRT997596	hsa-miR-378i	CLIP-seq
MIRT997597	hsa-miR-379	CLIP-seq
MIRT997598	hsa-miR-3911	CLIP-seq
MIRT997599	hsa-miR-3977	CLIP-seq
MIRT997600	hsa-miR-422a	CLIP-seq
MIRT997601	hsa-miR-424	CLIP-seq
MIRT997602	hsa-miR-4432	CLIP-seq
MIRT997603	hsa-miR-4438	CLIP-seq
MIRT997604	hsa-miR-4451	CLIP-seq
MIRT997605	hsa-miR-4487	CLIP-seq
MIRT997606	hsa-miR-4536	CLIP-seq
MIRT997607	hsa-miR-4635	CLIP-seq
MIRT997608	hsa-miR-4639-3p	CLIP-seq
MIRT997609	hsa-miR-4643	CLIP-seq
MIRT997610	hsa-miR-4650-3p	CLIP-seq
MIRT997611	hsa-miR-4652-3p	CLIP-seq
MIRT997612	hsa-miR-4659a-5p	CLIP-seq
MIRT997613	hsa-miR-4659b-5p	CLIP-seq
MIRT997614	hsa-miR-466	CLIP-seq
MIRT997615	hsa-miR-4666-5p	CLIP-seq
MIRT997616	hsa-miR-4667-5p	CLIP-seq
MIRT997617	hsa-miR-4675	CLIP-seq
MIRT997618	hsa-miR-4680-3p	CLIP-seq
MIRT997619	hsa-miR-4687-3p	CLIP-seq
MIRT997620	hsa-miR-4700-5p	CLIP-seq
MIRT997621	hsa-miR-4725-5p	CLIP-seq
MIRT997622	hsa-miR-4738-3p	CLIP-seq
MIRT997623	hsa-miR-4741	CLIP-seq
MIRT997624	hsa-miR-4747-5p	CLIP-seq
MIRT997625	hsa-miR-4776-3p	CLIP-seq
MIRT997626	hsa-miR-4789-3p	CLIP-seq
MIRT997627	hsa-miR-493	CLIP-seq
MIRT997628	hsa-miR-495	CLIP-seq
MIRT997629	hsa-miR-497	CLIP-seq
MIRT997630	hsa-miR-499-5p	CLIP-seq
MIRT997631	hsa-miR-504	CLIP-seq
MIRT997632	hsa-miR-516a-3p	CLIP-seq
MIRT997633	hsa-miR-520a-5p	CLIP-seq
MIRT997634	hsa-miR-525-5p	CLIP-seq
MIRT997635	hsa-miR-556-5p	CLIP-seq
MIRT997636	hsa-miR-558	CLIP-seq
MIRT997637	hsa-miR-619	CLIP-seq
MIRT997638	hsa-miR-644	CLIP-seq
MIRT997639	hsa-miR-761	CLIP-seq
MIRT997640	hsa-miR-769-5p	CLIP-seq
MIRT997641	hsa-miR-874	CLIP-seq
MIRT997642	hsa-miR-939	CLIP-seq
MIRT997643	hsa-miR-122	CLIP-seq
MIRT997644	hsa-miR-1254	CLIP-seq
MIRT997645	hsa-miR-1262	CLIP-seq
MIRT997646	hsa-miR-127-5p	CLIP-seq
MIRT997647	hsa-miR-130a	CLIP-seq
MIRT997648	hsa-miR-130b	CLIP-seq
MIRT997649	hsa-miR-2110	CLIP-seq
MIRT997650	hsa-miR-301a	CLIP-seq
MIRT997651	hsa-miR-301b	CLIP-seq
MIRT997652	hsa-miR-3116	CLIP-seq
MIRT997576	hsa-miR-3150a-3p	CLIP-seq
MIRT997653	hsa-miR-3156-5p	CLIP-seq
MIRT997654	hsa-miR-337-3p	CLIP-seq
MIRT997655	hsa-miR-3666	CLIP-seq
MIRT997656	hsa-miR-3667-5p	CLIP-seq
MIRT997657	hsa-miR-3688-3p	CLIP-seq
MIRT997658	hsa-miR-3978	CLIP-seq
MIRT997659	hsa-miR-4261	CLIP-seq
MIRT997660	hsa-miR-4271	CLIP-seq
MIRT997661	hsa-miR-4295	CLIP-seq
MIRT997662	hsa-miR-4496	CLIP-seq
MIRT997663	hsa-miR-454	CLIP-seq
MIRT997664	hsa-miR-4637	CLIP-seq
MIRT997665	hsa-miR-4687-5p	CLIP-seq
MIRT997666	hsa-miR-4700-3p	CLIP-seq
MIRT997667	hsa-miR-4701-3p	CLIP-seq
MIRT997668	hsa-miR-4725-3p	CLIP-seq
MIRT997669	hsa-miR-4728-3p	CLIP-seq
MIRT997670	hsa-miR-4731-3p	CLIP-seq
MIRT997671	hsa-miR-4781-3p	CLIP-seq
MIRT997672	hsa-miR-4786-3p	CLIP-seq
MIRT997673	hsa-miR-4797-5p	CLIP-seq
MIRT997674	hsa-miR-4801	CLIP-seq
MIRT997675	hsa-miR-485-3p	CLIP-seq
MIRT997676	hsa-miR-491-3p	CLIP-seq
MIRT997677	hsa-miR-508-5p	CLIP-seq
MIRT997678	hsa-miR-539	CLIP-seq
MIRT997679	hsa-miR-542-3p	CLIP-seq
MIRT997680	hsa-miR-561	CLIP-seq
MIRT997681	hsa-miR-566	CLIP-seq
MIRT997682	hsa-miR-652	CLIP-seq
MIRT997683	hsa-miR-653	CLIP-seq
MIRT997684	hsa-miR-656	CLIP-seq
MIRT997685	hsa-miR-661	CLIP-seq
MIRT997686	hsa-miR-766	CLIP-seq
MIRT997687	hsa-miR-875-3p	CLIP-seq
MIRT997688	hsa-miR-889	CLIP-seq
MIRT997689	hsa-miR-1264	CLIP-seq
MIRT997690	hsa-miR-1278	CLIP-seq
MIRT997691	hsa-miR-1297	CLIP-seq
MIRT997692	hsa-miR-140-3p	CLIP-seq
MIRT997560	hsa-miR-1470	CLIP-seq
MIRT997693	hsa-miR-149	CLIP-seq
MIRT997561	hsa-miR-15a	CLIP-seq
MIRT997562	hsa-miR-15b	CLIP-seq
MIRT997563	hsa-miR-16	CLIP-seq
MIRT997564	hsa-miR-1909	CLIP-seq
MIRT997566	hsa-miR-195	CLIP-seq
MIRT997567	hsa-miR-203	CLIP-seq
MIRT997571	hsa-miR-214	CLIP-seq
MIRT997694	hsa-miR-24	CLIP-seq
MIRT997695	hsa-miR-26a	CLIP-seq
MIRT997696	hsa-miR-26b	CLIP-seq
MIRT997697	hsa-miR-3159	CLIP-seq
MIRT997578	hsa-miR-3160-3p	CLIP-seq
MIRT997582	hsa-miR-320e	CLIP-seq
MIRT997585	hsa-miR-3619-5p	CLIP-seq
MIRT997589	hsa-miR-378	CLIP-seq
MIRT997590	hsa-miR-378b	CLIP-seq
MIRT997591	hsa-miR-378c	CLIP-seq
MIRT997592	hsa-miR-378d	CLIP-seq
MIRT997593	hsa-miR-378e	CLIP-seq
MIRT997594	hsa-miR-378f	CLIP-seq
MIRT997595	hsa-miR-378h	CLIP-seq
MIRT997596	hsa-miR-378i	CLIP-seq
MIRT997600	hsa-miR-422a	CLIP-seq
MIRT997601	hsa-miR-424	CLIP-seq
MIRT997698	hsa-miR-4284	CLIP-seq
MIRT997699	hsa-miR-4465	CLIP-seq
MIRT997700	hsa-miR-4469	CLIP-seq
MIRT997605	hsa-miR-4487	CLIP-seq
MIRT997701	hsa-miR-451b	CLIP-seq
MIRT997702	hsa-miR-4667-3p	CLIP-seq
MIRT997617	hsa-miR-4675	CLIP-seq
MIRT997619	hsa-miR-4687-3p	CLIP-seq
MIRT997623	hsa-miR-4741	CLIP-seq
MIRT997703	hsa-miR-483-3p	CLIP-seq
MIRT997629	hsa-miR-497	CLIP-seq
MIRT997635	hsa-miR-556-5p	CLIP-seq
MIRT997636	hsa-miR-558	CLIP-seq
MIRT997704	hsa-miR-633	CLIP-seq
MIRT997639	hsa-miR-761	CLIP-seq
MIRT997644	hsa-miR-1254	CLIP-seq
MIRT997652	hsa-miR-3116	CLIP-seq
MIRT997684	hsa-miR-656	CLIP-seq
MIRT997685	hsa-miR-661	CLIP-seq
MIRT997688	hsa-miR-889	CLIP-seq
MIRT1995735	hsa-miR-4318	CLIP-seq
MIRT997701	hsa-miR-451b	CLIP-seq
MIRT1995736	hsa-miR-4693-5p	CLIP-seq
MIRT1995737	hsa-miR-4766-3p	CLIP-seq
MIRT1995738	hsa-miR-548aa	CLIP-seq
MIRT1995739	hsa-miR-548ag	CLIP-seq
MIRT1995740	hsa-miR-548ai	CLIP-seq
MIRT1995741	hsa-miR-548m	CLIP-seq
MIRT1995742	hsa-miR-548p	CLIP-seq
MIRT1995743	hsa-miR-892a	CLIP-seq
MIRT1995744	hsa-miR-1208	CLIP-seq
MIRT1995745	hsa-miR-3119	CLIP-seq
MIRT2388013	hsa-miR-1267	CLIP-seq
MIRT1995735	hsa-miR-4318	CLIP-seq
MIRT997611	hsa-miR-4652-3p	CLIP-seq
MIRT1995736	hsa-miR-4693-5p	CLIP-seq
MIRT997640	hsa-miR-769-5p	CLIP-seq
MIRT1995743	hsa-miR-892a	CLIP-seq
MIRT2449714	hsa-miR-1976	CLIP-seq
MIRT2449715	hsa-miR-2355-5p	CLIP-seq
MIRT2449716	hsa-miR-3151	CLIP-seq
MIRT2449717	hsa-miR-3165	CLIP-seq
MIRT2449718	hsa-miR-323b-3p	CLIP-seq
MIRT2449719	hsa-miR-3622a-3p	CLIP-seq
MIRT2449720	hsa-miR-3622b-3p	CLIP-seq
MIRT2449721	hsa-miR-3622b-5p	CLIP-seq
MIRT2449722	hsa-miR-3662	CLIP-seq
MIRT2449723	hsa-miR-3679-3p	CLIP-seq
MIRT2449724	hsa-miR-4279	CLIP-seq
MIRT2449725	hsa-miR-4433	CLIP-seq
MIRT2449726	hsa-miR-4446-5p	CLIP-seq
MIRT2449727	hsa-miR-4459	CLIP-seq
MIRT2449728	hsa-miR-4532	CLIP-seq
MIRT2449729	hsa-miR-4645-5p	CLIP-seq
MIRT2449730	hsa-miR-4673	CLIP-seq
MIRT2449731	hsa-miR-4716-5p	CLIP-seq
MIRT2449732	hsa-miR-4722-3p	CLIP-seq
MIRT2449733	hsa-miR-4738-5p	CLIP-seq
MIRT2449734	hsa-miR-4755-3p	CLIP-seq
MIRT2449735	hsa-miR-4768-3p	CLIP-seq
MIRT2449736	hsa-miR-4775	CLIP-seq
MIRT2449737	hsa-miR-544b	CLIP-seq
MIRT2449738	hsa-miR-552	CLIP-seq
MIRT2449739	hsa-miR-576-3p	CLIP-seq
MIRT2449740	hsa-miR-587	CLIP-seq
MIRT2449741	hsa-miR-590-3p	CLIP-seq
MIRT2533665	hsa-miR-1202	CLIP-seq
MIRT2533666	hsa-miR-1207-3p	CLIP-seq
MIRT2388013	hsa-miR-1267	CLIP-seq
MIRT2533667	hsa-miR-1270	CLIP-seq
MIRT997690	hsa-miR-1278	CLIP-seq
MIRT997691	hsa-miR-1297	CLIP-seq
MIRT997560	hsa-miR-1470	CLIP-seq
MIRT997561	hsa-miR-15a	CLIP-seq
MIRT997562	hsa-miR-15b	CLIP-seq
MIRT997563	hsa-miR-16	CLIP-seq
MIRT2533668	hsa-miR-193a-3p	CLIP-seq
MIRT2533669	hsa-miR-193b	CLIP-seq
MIRT997566	hsa-miR-195	CLIP-seq
MIRT997568	hsa-miR-208a	CLIP-seq
MIRT997569	hsa-miR-208b	CLIP-seq
MIRT997571	hsa-miR-214	CLIP-seq
MIRT997695	hsa-miR-26a	CLIP-seq
MIRT997696	hsa-miR-26b	CLIP-seq
MIRT2533670	hsa-miR-3064-5p	CLIP-seq
MIRT997574	hsa-miR-3117-5p	CLIP-seq
MIRT997576	hsa-miR-3150a-3p	CLIP-seq
MIRT997577	hsa-miR-3157-3p	CLIP-seq
MIRT997579	hsa-miR-3175	CLIP-seq
MIRT2533671	hsa-miR-3177-5p	CLIP-seq
MIRT997581	hsa-miR-3190	CLIP-seq
MIRT2533672	hsa-miR-3200-5p	CLIP-seq
MIRT2533673	hsa-miR-329	CLIP-seq
MIRT2533674	hsa-miR-331-3p	CLIP-seq
MIRT997585	hsa-miR-3619-5p	CLIP-seq
MIRT2533675	hsa-miR-362-3p	CLIP-seq
MIRT997586	hsa-miR-3658	CLIP-seq
MIRT2533676	hsa-miR-3673	CLIP-seq
MIRT2449723	hsa-miR-3679-3p	CLIP-seq
MIRT2533677	hsa-miR-369-3p	CLIP-seq
MIRT2533678	hsa-miR-374c	CLIP-seq
MIRT2533679	hsa-miR-377	CLIP-seq
MIRT2533680	hsa-miR-3941	CLIP-seq
MIRT2533681	hsa-miR-3972	CLIP-seq
MIRT997601	hsa-miR-424	CLIP-seq
MIRT2533682	hsa-miR-4276	CLIP-seq
MIRT2533683	hsa-miR-4286	CLIP-seq
MIRT2533684	hsa-miR-4299	CLIP-seq
MIRT1995735	hsa-miR-4318	CLIP-seq
MIRT2533685	hsa-miR-432	CLIP-seq
MIRT997602	hsa-miR-4432	CLIP-seq
MIRT997699	hsa-miR-4465	CLIP-seq
MIRT2533686	hsa-miR-4642	CLIP-seq
MIRT997609	hsa-miR-4643	CLIP-seq
MIRT997611	hsa-miR-4652-3p	CLIP-seq
MIRT997614	hsa-miR-466	CLIP-seq
MIRT997615	hsa-miR-4666-5p	CLIP-seq
MIRT997616	hsa-miR-4667-5p	CLIP-seq
MIRT2533687	hsa-miR-4682	CLIP-seq
MIRT2533688	hsa-miR-4683	CLIP-seq
MIRT997619	hsa-miR-4687-3p	CLIP-seq
MIRT1995736	hsa-miR-4693-5p	CLIP-seq
MIRT997620	hsa-miR-4700-5p	CLIP-seq
MIRT2533689	hsa-miR-4715-3p	CLIP-seq
MIRT2533690	hsa-miR-4720-5p	CLIP-seq
MIRT997624	hsa-miR-4747-5p	CLIP-seq
MIRT997625	hsa-miR-4776-3p	CLIP-seq
MIRT997626	hsa-miR-4789-3p	CLIP-seq
MIRT2533691	hsa-miR-4799-3p	CLIP-seq
MIRT997629	hsa-miR-497	CLIP-seq
MIRT997630	hsa-miR-499-5p	CLIP-seq
MIRT2533692	hsa-miR-603	CLIP-seq
MIRT2533693	hsa-miR-620	CLIP-seq
MIRT2533694	hsa-miR-627	CLIP-seq
MIRT2533695	hsa-miR-655	CLIP-seq
MIRT997639	hsa-miR-761	CLIP-seq
MIRT997640	hsa-miR-769-5p	CLIP-seq
MIRT997641	hsa-miR-874	CLIP-seq
MIRT1995743	hsa-miR-892a	CLIP-seq
MIRT2533696	hsa-miR-892b	CLIP-seq
MIRT2533697	hsa-miR-924	CLIP-seq
MIRT997642	hsa-miR-939	CLIP-seq

Show/Hide all (26)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003755	Function	Peptidyl-prolyl cis-trans isomerase activity	IBA
GO:0003755	Function	Peptidyl-prolyl cis-trans isomerase activity	IDA	11350175
GO:0003755	Function	Peptidyl-prolyl cis-trans isomerase activity	IEA
GO:0005515	Function	Protein binding	IPI	14676191, 14743216, 19615732, 19875381, 20562859, 21170051, 21360678, 23455922, 23602568, 24169621, 24981860, 25036637, 25852190, 27086506, 28514442, 29079741, 30021884, 30382094, 32296183, 32707033, 33961781, 34591612, 35271311
GO:0005528	Function	FK506 binding	IEA
GO:0005528	Function	FK506 binding	TAS	9001212
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IC	28147277
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0006457	Process	Protein folding	IBA
GO:0006457	Process	Protein folding	IDA	11350175
GO:0006457	Process	Protein folding	TAS	9001212
GO:0009617	Process	Response to bacterium	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0016853	Function	Isomerase activity	IEA
GO:0030674	Function	Protein-macromolecule adaptor activity	IDA	28147277
GO:0031072	Function	Heat shock protein binding	IEA
GO:0031072	Function	Heat shock protein binding	IPI	9660753
GO:0042220	Process	Response to cocaine	IEA
GO:0043491	Process	Phosphatidylinositol 3-kinase/protein kinase B signal transduction	IDA	28147277
GO:0051898	Process	Negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IMP	17386267
GO:0070062	Component	Extracellular exosome	HDA	19056867
GO:0097305	Process	Response to alcohol	IEA

MIM	HGNC	e!Ensembl
602623	3721	ENSG00000096060

Q13451

Protein name

Peptidyl-prolyl cis-trans isomerase FKBP5 (PPIase FKBP5) (EC 5.2.1.8) (51 kDa FK506-binding protein) (51 kDa FKBP) (FKBP-51) (54 kDa progesterone receptor-associated immunophilin) (Androgen-regulated protein 6) (FF1 antigen) (FK506-binding protein 5) (FKB

Protein function

Immunophilin protein with PPIase and co-chaperone activities (PubMed:11350175). Component of unligated steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). Plays a role in the intracellular trafficking of het

PDB

1KT0 , 3O5D , 3O5E , 3O5F , 3O5G , 3O5I , 3O5J , 3O5K , 3O5L , 3O5M , 3O5O , 3O5P , 3O5Q , 3O5R , 4DRH , 4DRI , 4DRK , 4DRM , 4DRN , 4DRO , 4DRP , 4DRQ , 4JFI , 4JFJ , 4JFK , 4JFL , 4JFM , 4R0X , 4TW6 , 4TW7 , 4TX0 , 4W9O , 4W9P , 4W9Q , 5BXJ , 5DIT , 5DIU , 5DIV , 5NJX , 5OBK , 5OMP , 6SAF , 6TX4 , 6TX5 , 6TX6 , 6TX7 , 6TX8 , 6TX9 , 6TXX , 7A6W , 7A6X

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00254	FKBP_C	43 → 135	FKBP-type peptidyl-prolyl cis-trans isomerase	Domain
PF00254	FKBP_C	158 → 248	FKBP-type peptidyl-prolyl cis-trans isomerase	Domain
PF00515	TPR_1	318 → 350	Tetratricopeptide repeat	Repeat

Tissue specificity

TISSUE SPECIFICITY: Widely expressed, enriched in testis compared to other tissues.

Sequence

MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK
LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP
KIPSNATLFFEIELLDFKGEDLFEDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGGRM
FDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAE
LIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEM
EYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEA
QLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAEQD
AKEEANKAMGKKTSEGVTNEKGTDSQAMEEEKPEGHV

Sequence length

457

Interactions

View interactions

	KEGG		Reactome
	Estrogen signaling pathway		HSP90 chaperone cycle for steroid hormone receptors (SHR) ESR-mediated signaling

Show/Hide Unknown Diseases (4)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Antidepressant drug treatment, accelerated response to	drug response; risk factor	rs1360780	RCV000007401
Asthma	risk factor	rs1581842283	RCV000791245
Post-traumatic stress disorder	Likely risk allele	rs1360780	RCV002481079
Susceptibility to severe depressive disorder	Likely risk allele	rs6926133, rs9380525, rs737054, rs9470079, rs4713902, rs4713916	RCV003128203 RCV003128205 RCV003128206 RCV003128207 RCV003128208 RCV003128204

Show/Hide Text Mining Associations (100)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Adenocarcinoma	Associate	29052817, 34417596
Alzheimer Disease	Associate	35205209
Anxiety	Associate	23274505, 26424511, 28300138, 28364727, 29466454, 30036794, 30334356, 31908177, 31931271, 33705478, 34715840, 35205209, 38460581
Anxiety Disorders	Associate	23406438, 24253961, 24411633, 24756342
Arthritis Rheumatoid	Associate	17082220, 36941600
Asthma	Associate	39868576
Atrial Fibrillation	Associate	25706326
Attention Deficit and Disruptive Behavior Disorders	Associate	26228411
Binge Drinking	Associate	31931271
Bipolar Disorder	Associate	18180755, 24345775, 25522387, 28002634, 28030643, 30524168
Borderline Personality Disorder	Associate	25047302
Breast Neoplasms	Associate	31908177, 37987640
Bruck syndrome 1	Associate	27298363
Carcinoma Hepatocellular	Associate	35865544
Cardiomyopathies	Associate	32631246
Cardiomyopathy Dilated	Associate	34713710
Cardiovascular Diseases	Associate	29951131
Cognition Disorders	Associate	30524168
Colorectal Neoplasms	Associate	28441737
Coronary Disease	Associate	32860562
Creutzfeldt Jakob Disease Sporadic	Associate	32918118
Cushing Syndrome	Associate	27664120, 34914631, 36329530
Death	Associate	27389186
Delirium	Inhibit	35017578
Delirium	Associate	35017578
Depressive Disorder	Associate	17081296, 18180755, 23406438, 24411633, 24756342, 26424511, 26740367, 28590587, 29466454, 29936334, 30036794, 31908177, 31931271, 32699209, 32860562, 37628589 View all (1 more)
Depressive Disorder Major	Associate	18180755, 20726698, 23406438, 26371764, 28002634, 29182159, 31113877, 36825897
Diabetes Mellitus Type 2	Associate	29951131
Diabetes Mellitus Type 2	Stimulate	30032404
Diabetic Nephropathies	Associate	34858345, 37745718, 40114624
Dissociative Disorders	Associate	26424511
Dyslipidemias	Associate	32860562
Eosinophilic Esophagitis	Associate	20371398
Epilepsy	Associate	36825897, 37078238, 37628589
Epilepsy Post Traumatic	Associate	28002634
Fibrocartilaginous embolism	Associate	33135363
Fibrosis	Associate	34858345
Glioma	Associate	18320068
Glomerulonephritis IGA	Stimulate	39516745
Glucocorticoid Receptor Deficiency	Associate	32699209
Hamartoma Syndrome Multiple	Associate	27664120
Headache	Associate	37078238
Heart Diseases	Associate	34713710
HIV Infections	Associate	20726698
HIV Infections	Stimulate	29936334
Hyperandrogenism	Associate	35787810
Hypersplenism	Associate	35865544
Inflammation	Associate	31113877, 32958048, 34713710, 34858345
Influenza Human	Associate	32580383
Insulin Resistance	Associate	30032404, 32958048
Iron Overload	Associate	34713710
Kidney Failure Chronic	Associate	34858345
Labor Pain	Inhibit	20629487
Learning Disabilities	Associate	28002634
Leiomyoma	Associate	35426036
Leukoencephalopathies	Associate	24253961
Melanoma	Associate	28434031
Mental Disorders	Associate	23201972, 23274505, 23407841, 25115650, 25331639, 26424511, 26740367, 27196697, 27915167, 28030643, 34780285, 36729133, 38460581
Mood Disorders	Associate	23407841, 27389186, 33829973
Myocardial Infarction	Associate	31113877
Nasopharyngeal Carcinoma	Associate	36769373
Neglected Diseases	Associate	22979952
Neoplasms	Associate	18757419
Neoplasms Adipose Tissue	Associate	32958048
Neurobehavioral Manifestations	Associate	36729133
Neurocognitive Disorders	Associate	37285328
Neurodegenerative Diseases	Associate	35205209
Neurologic Manifestations	Associate	37285328
Obesity	Inhibit	32958048
Obesity	Associate	34267209, 35817784, 39868576
Occupational Stress	Associate	27389186
Osteoporosis	Associate	34914631
Paget Disease Extramammary	Associate	34895219
Pancreatic Neoplasms	Associate	23936393
Paranoid Disorders	Associate	27389186
Phobia Social	Associate	28002634, 29466454
Polycystic Ovary Syndrome	Associate	34267209, 35787810
Precursor Cell Lymphoblastic Leukemia Lymphoma	Associate	30575921
Prostatic Hyperplasia	Associate	19676094
Prostatic Neoplasms	Associate	25829060
Psychological Distress	Associate	23406438, 27389186, 32860562, 37078238
Psychological Trauma	Associate	28002634
Psychotic Disorders	Associate	24345775, 27389186
Pulmonary Disease Chronic Obstructive	Associate	31022961
Renal Insufficiency Chronic	Associate	24253112
Retinitis Pigmentosa Concentric	Associate	25331639
Schizophrenia	Stimulate	24345775, 36729133
Schizophrenia	Associate	30524168
Seizures	Associate	36825897
Signs and Symptoms	Associate	26588823
Sleep Wake Disorders	Associate	36743961
ST Elevation Myocardial Infarction	Associate	26367242, 31863085
Status Asthmaticus	Stimulate	28045928
Stress Disorders Post Traumatic	Associate	23407841, 24253961, 25115650, 25331639, 27754486, 30862937
Substance Related Disorders	Associate	22979952, 30862937
Temporomandibular Joint Disorders	Associate	40435063
Trauma and Stressor Related Disorders	Associate	24411633, 24756342, 33541187
Trigeminal Neuralgia	Associate	38158702
Ventricular Remodeling	Associate	34713710
Wounds and Injuries	Associate	22979952, 23201972, 27196697, 31113877

FKBP5 (FKBP prolyl isomerase 5)