Gene Gene information from NCBI Gene database.
Entrez ID 22885
Gene name Actin binding LIM protein family member 3
Gene symbol ABLIM3
Synonyms (NCBI Gene)
HMFN1661
Chromosome 5
Chromosome location 5q32
Summary This gene encodes a member of the actin-binding LIM (abLIM) family of proteins. These proteins are characterized by an N-terminal LIM domain and a C-terminal dematin-like domain. The encoded protein interacts with actin filaments and may be a component of
miRNA miRNA information provided by mirtarbase database.
375
miRTarBase ID miRNA Experiments Reference
MIRT437668 hsa-miR-214-3p MicroarrayqRT-PCR 22815788
MIRT760947 hsa-miR-103a CLIP-seq
MIRT760948 hsa-miR-107 CLIP-seq
MIRT760949 hsa-miR-1301 CLIP-seq
MIRT760950 hsa-miR-1908 CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
23
GO ID Ontology Definition Evidence Reference
GO:0001725 Component Stress fiber IBA
GO:0001725 Component Stress fiber IDA 22684256
GO:0001725 Component Stress fiber IEA
GO:0003779 Function Actin binding IEA
GO:0005515 Function Protein binding IPI 25416956, 31515488, 32296183
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
611305 29132 ENSG00000173210
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O94929
Protein name Actin-binding LIM protein 3 (abLIM-3) (Actin-binding LIM protein family member 3)
Protein function May act as scaffold protein. May stimulate ABRA activity and ABRA-dependent SRF transcriptional activity.
PDB 1UJS , 2DJ7
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00412 LIM 23 78 LIM domain Domain
PF00412 LIM 82 138 LIM domain Domain
PF00412 LIM 151 206 LIM domain Domain
PF00412 LIM 210 269 LIM domain Domain
PF16182 AbLIM_anchor 273 647 Putative adherens-junction anchoring region of AbLIM Family
PF02209 VHP 648 683 Villin headpiece domain Domain
Tissue specificity TISSUE SPECIFICITY: Expressed predominantly in heart and brain. {ECO:0000269|PubMed:17194709}.
Sequence
Sequence length 683
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG 
  Axon guidance