Gene Gene information from NCBI Gene database.
Entrez ID 22879
Gene name MON1 vesicular trafficking associated B
Gene symbol MON1B
Synonyms (NCBI Gene)
HSRG1SAND2SRG1
Chromosome 16
Chromosome location 16q23.1
miRNA miRNA information provided by mirtarbase database.
609
miRTarBase ID miRNA Experiments Reference
MIRT048627 hsa-miR-99a-5p CLASH 23622248
MIRT038816 hsa-miR-93-3p CLASH 23622248
MIRT719852 hsa-miR-2114-5p HITS-CLIP 19536157
MIRT719851 hsa-miR-345-3p HITS-CLIP 19536157
MIRT719850 hsa-miR-4732-3p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
8
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 20434987, 21509660
GO:0005737 Component Cytoplasm IDA 21509660
GO:0006623 Process Protein targeting to vacuole IEA
GO:0016192 Process Vesicle-mediated transport IEA
GO:0019085 Process Early viral transcription IDA 21509660
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
608954 25020 ENSG00000103111
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q7L1V2
Protein name Vacuolar fusion protein MON1 homolog B (HSV-1 stimulation-related gene 1 protein) (HSV-I stimulating-related protein)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF19036 Fuz_longin_1 110 232 First Longin domain of FUZ, MON1 and HPS1 Domain
PF19037 Fuz_longin_2 273 370 Second Longin domain of FUZ, MON1 and HPS1 Domain
PF19038 Fuz_longin_3 409 516 Third Longin domain of FUZ, MON1 and HPS1 Domain
Sequence
Sequence length 547
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  Mitophagy - animal   RAB GEFs exchange GTP for GDP on RABs
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
12
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
CENTRAL NERVOUS SYSTEM CANCER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
EOSINOPHILIC ESOPHAGITIS GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
GLIOBLASTOMA MULTIFORME GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
GLIOMA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations