Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	22878
Gene name Gene Name - the full gene name approved by the HGNC.	Trafficking protein particle complex subunit 8
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	TRAPPC8
Synonyms (NCBI Gene) Gene synonyms aliases	GSG1, HsT2706, KIAA1012, TRS85
Chromosome Chromosome number	18
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	18q12.1

Show/Hide all(178)

miRTarBase ID	miRNA	Experiments	Reference
MIRT652225	hsa-miR-1323	HITS-CLIP	23824327
MIRT652224	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT652223	hsa-miR-3148	HITS-CLIP	23824327
MIRT652222	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT652221	hsa-miR-607	HITS-CLIP	23824327
MIRT652225	hsa-miR-1323	HITS-CLIP	23824327
MIRT652224	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT652223	hsa-miR-3148	HITS-CLIP	23824327
MIRT652222	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT652221	hsa-miR-607	HITS-CLIP	23824327
MIRT652225	hsa-miR-1323	HITS-CLIP	23824327
MIRT652224	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT652223	hsa-miR-3148	HITS-CLIP	23824327
MIRT652222	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT652221	hsa-miR-607	HITS-CLIP	23824327
MIRT652225	hsa-miR-1323	HITS-CLIP	23824327
MIRT652224	hsa-miR-548o-3p	HITS-CLIP	23824327
MIRT652223	hsa-miR-3148	HITS-CLIP	23824327
MIRT652222	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT652221	hsa-miR-607	HITS-CLIP	23824327
MIRT1452203	hsa-miR-105	CLIP-seq
MIRT1452204	hsa-miR-1245b-5p	CLIP-seq
MIRT1452205	hsa-miR-1278	CLIP-seq
MIRT1452206	hsa-miR-128	CLIP-seq
MIRT1452207	hsa-miR-1290	CLIP-seq
MIRT1452208	hsa-miR-1303	CLIP-seq
MIRT1452209	hsa-miR-135a	CLIP-seq
MIRT1452210	hsa-miR-135b	CLIP-seq
MIRT1452211	hsa-miR-141	CLIP-seq
MIRT1452212	hsa-miR-151-3p	CLIP-seq
MIRT1452213	hsa-miR-15a	CLIP-seq
MIRT1452214	hsa-miR-15b	CLIP-seq
MIRT1452215	hsa-miR-16	CLIP-seq
MIRT1452216	hsa-miR-194	CLIP-seq
MIRT1452217	hsa-miR-195	CLIP-seq
MIRT1452218	hsa-miR-200a	CLIP-seq
MIRT1452219	hsa-miR-27a	CLIP-seq
MIRT1452220	hsa-miR-27b	CLIP-seq
MIRT1452221	hsa-miR-3124-3p	CLIP-seq
MIRT1452222	hsa-miR-3142	CLIP-seq
MIRT1452223	hsa-miR-3167	CLIP-seq
MIRT1452224	hsa-miR-320a	CLIP-seq
MIRT1452225	hsa-miR-320b	CLIP-seq
MIRT1452226	hsa-miR-320c	CLIP-seq
MIRT1452227	hsa-miR-320d	CLIP-seq
MIRT1452228	hsa-miR-320e	CLIP-seq
MIRT1452229	hsa-miR-365	CLIP-seq
MIRT1452230	hsa-miR-3691-5p	CLIP-seq
MIRT1452231	hsa-miR-382	CLIP-seq
MIRT1452232	hsa-miR-3920	CLIP-seq
MIRT1452233	hsa-miR-3921	CLIP-seq
MIRT1452234	hsa-miR-3922-5p	CLIP-seq
MIRT1452235	hsa-miR-424	CLIP-seq
MIRT1452236	hsa-miR-4330	CLIP-seq
MIRT1452237	hsa-miR-4429	CLIP-seq
MIRT1452238	hsa-miR-4433	CLIP-seq
MIRT1452239	hsa-miR-4641	CLIP-seq
MIRT1452240	hsa-miR-4653-5p	CLIP-seq
MIRT1452241	hsa-miR-4752	CLIP-seq
MIRT1452242	hsa-miR-4771	CLIP-seq
MIRT1452243	hsa-miR-4775	CLIP-seq
MIRT1452244	hsa-miR-4804-3p	CLIP-seq
MIRT1452245	hsa-miR-497	CLIP-seq
MIRT1452246	hsa-miR-499a-5p	CLIP-seq
MIRT1452247	hsa-miR-513a-5p	CLIP-seq
MIRT1452248	hsa-miR-548c-3p	CLIP-seq
MIRT1452249	hsa-miR-590-3p	CLIP-seq
MIRT1452250	hsa-miR-876-5p	CLIP-seq
MIRT1452251	hsa-miR-922	CLIP-seq
MIRT2135392	hsa-miR-3611	CLIP-seq
MIRT2135393	hsa-miR-4477b	CLIP-seq
MIRT2135394	hsa-miR-451b	CLIP-seq
MIRT2135395	hsa-miR-4696	CLIP-seq
MIRT2135396	hsa-miR-548o	CLIP-seq
MIRT2135397	hsa-miR-892a	CLIP-seq
MIRT1452205	hsa-miR-1278	CLIP-seq
MIRT1452206	hsa-miR-128	CLIP-seq
MIRT1452208	hsa-miR-1303	CLIP-seq
MIRT1452209	hsa-miR-135a	CLIP-seq
MIRT1452210	hsa-miR-135b	CLIP-seq
MIRT2356506	hsa-miR-144	CLIP-seq
MIRT2356507	hsa-miR-200b	CLIP-seq
MIRT2356508	hsa-miR-200c	CLIP-seq
MIRT2356509	hsa-miR-224	CLIP-seq
MIRT1452219	hsa-miR-27a	CLIP-seq
MIRT1452220	hsa-miR-27b	CLIP-seq
MIRT2356510	hsa-miR-3074-3p	CLIP-seq
MIRT1452224	hsa-miR-320a	CLIP-seq
MIRT1452225	hsa-miR-320b	CLIP-seq
MIRT1452226	hsa-miR-320c	CLIP-seq
MIRT1452227	hsa-miR-320d	CLIP-seq
MIRT1452228	hsa-miR-320e	CLIP-seq
MIRT2356511	hsa-miR-331-5p	CLIP-seq
MIRT2356512	hsa-miR-3607-3p	CLIP-seq
MIRT2135392	hsa-miR-3611	CLIP-seq
MIRT2356513	hsa-miR-3671	CLIP-seq
MIRT2356514	hsa-miR-369-3p	CLIP-seq
MIRT2356515	hsa-miR-374a	CLIP-seq
MIRT2356516	hsa-miR-374b	CLIP-seq
MIRT2356517	hsa-miR-3924	CLIP-seq
MIRT2356518	hsa-miR-429	CLIP-seq
MIRT1452237	hsa-miR-4429	CLIP-seq
MIRT1452238	hsa-miR-4433	CLIP-seq
MIRT2356519	hsa-miR-4678	CLIP-seq
MIRT2356520	hsa-miR-4705	CLIP-seq
MIRT2356521	hsa-miR-4714-3p	CLIP-seq
MIRT2356522	hsa-miR-4718	CLIP-seq
MIRT1452244	hsa-miR-4804-3p	CLIP-seq
MIRT1452247	hsa-miR-513a-5p	CLIP-seq
MIRT2356523	hsa-miR-548aa	CLIP-seq
MIRT2356524	hsa-miR-568	CLIP-seq
MIRT2650074	hsa-miR-1266	CLIP-seq
MIRT2650075	hsa-miR-1273f	CLIP-seq
MIRT1452205	hsa-miR-1278	CLIP-seq
MIRT2650076	hsa-miR-143	CLIP-seq
MIRT1452212	hsa-miR-151-3p	CLIP-seq
MIRT2650077	hsa-miR-186	CLIP-seq
MIRT2650078	hsa-miR-18a	CLIP-seq
MIRT2650079	hsa-miR-18b	CLIP-seq
MIRT2650080	hsa-miR-3133	CLIP-seq
MIRT2650081	hsa-miR-3184	CLIP-seq
MIRT2650082	hsa-miR-330-3p	CLIP-seq
MIRT2650083	hsa-miR-3664-3p	CLIP-seq
MIRT2650084	hsa-miR-3675-5p	CLIP-seq
MIRT2650085	hsa-miR-423-5p	CLIP-seq
MIRT2650086	hsa-miR-4272	CLIP-seq
MIRT2650087	hsa-miR-4282	CLIP-seq
MIRT2650088	hsa-miR-4283	CLIP-seq
MIRT2650089	hsa-miR-4422	CLIP-seq
MIRT2650090	hsa-miR-4426	CLIP-seq
MIRT1452238	hsa-miR-4433	CLIP-seq
MIRT2650091	hsa-miR-4489	CLIP-seq
MIRT2650092	hsa-miR-4495	CLIP-seq
MIRT2650093	hsa-miR-4518	CLIP-seq
MIRT2650094	hsa-miR-4647	CLIP-seq
MIRT2650095	hsa-miR-4662b	CLIP-seq
MIRT2650096	hsa-miR-4708-5p	CLIP-seq
MIRT2650097	hsa-miR-4711-5p	CLIP-seq
MIRT2650098	hsa-miR-4719	CLIP-seq
MIRT2650099	hsa-miR-4728-3p	CLIP-seq
MIRT2650100	hsa-miR-4735-3p	CLIP-seq
MIRT2650101	hsa-miR-4742-3p	CLIP-seq
MIRT2650102	hsa-miR-4770	CLIP-seq
MIRT1452244	hsa-miR-4804-3p	CLIP-seq
MIRT2650103	hsa-miR-486-5p	CLIP-seq
MIRT2135396	hsa-miR-548o	CLIP-seq
MIRT2650104	hsa-miR-556-5p	CLIP-seq
MIRT2650105	hsa-miR-599	CLIP-seq
MIRT2650106	hsa-miR-629	CLIP-seq
MIRT2650107	hsa-miR-944	CLIP-seq
MIRT2650074	hsa-miR-1266	CLIP-seq
MIRT1452205	hsa-miR-1278	CLIP-seq
MIRT1452212	hsa-miR-151-3p	CLIP-seq
MIRT2650077	hsa-miR-186	CLIP-seq
MIRT2650078	hsa-miR-18a	CLIP-seq
MIRT2650079	hsa-miR-18b	CLIP-seq
MIRT2650080	hsa-miR-3133	CLIP-seq
MIRT2650083	hsa-miR-3664-3p	CLIP-seq
MIRT2650084	hsa-miR-3675-5p	CLIP-seq
MIRT2650088	hsa-miR-4283	CLIP-seq
MIRT2650090	hsa-miR-4426	CLIP-seq
MIRT1452238	hsa-miR-4433	CLIP-seq
MIRT2650091	hsa-miR-4489	CLIP-seq
MIRT2650092	hsa-miR-4495	CLIP-seq
MIRT2650093	hsa-miR-4518	CLIP-seq
MIRT2650094	hsa-miR-4647	CLIP-seq
MIRT2650095	hsa-miR-4662b	CLIP-seq
MIRT2650098	hsa-miR-4719	CLIP-seq
MIRT2650099	hsa-miR-4728-3p	CLIP-seq
MIRT2650100	hsa-miR-4735-3p	CLIP-seq
MIRT2650101	hsa-miR-4742-3p	CLIP-seq
MIRT1452244	hsa-miR-4804-3p	CLIP-seq
MIRT2650103	hsa-miR-486-5p	CLIP-seq
MIRT2135396	hsa-miR-548o	CLIP-seq
MIRT2650104	hsa-miR-556-5p	CLIP-seq
MIRT2650105	hsa-miR-599	CLIP-seq
MIRT2650106	hsa-miR-629	CLIP-seq
MIRT2650107	hsa-miR-944	CLIP-seq

Show/Hide all(10)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000407	Component	Phagophore assembly site	IBA	21873635
GO:0005515	Function	Protein binding	IPI	21453443, 21525244
GO:0005829	Component	Cytosol	TAS
GO:0006888	Process	Endoplasmic reticulum to Golgi vesicle-mediated transport	IBA	21873635
GO:0007030	Process	Golgi organization	IMP	21525244
GO:0030008	Component	TRAPP complex	IDA	21525244
GO:0030242	Process	Autophagy of peroxisome	IBA	21873635
GO:0031410	Component	Cytoplasmic vesicle	IBA	21873635
GO:0034497	Process	Protein localization to phagophore assembly site	IBA	21873635
GO:1990072	Component	TRAPPIII protein complex	IBA	21873635

MIM	HGNC	e!Ensembl
614136	29169	ENSG00000153339

Protein

UniProt ID

Q9Y2L5

Protein name

Trafficking protein particle complex subunit 8 (Protein TRS85 homolog)

Protein function

Plays a role in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage (PubMed:21525244). Maintains together with TBC1D14 the cycling pool of ATG9 required for initiation of autophagy (PubMed:26711178). Involved in collagen s

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF12739	TRAPPC-Trs85	157 → 604	ER-Golgi trafficking TRAPP I complex 85 kDa subunit	Family

Sequence

MAQCVQSVQELIPDSFVPCVAALCSDEAERLTRLNHLSFAELLKPFSRLTSEVHMRDPNN
QLHVIKNLKIAVSNIVTQPPQPGAIRKLLNDVVSGSQPAEGLVANVITAGDYDLNISATT
PWFESYRETFLQSMPALDHEFLNHYLACMLVASSSEAEPVEQFSKLSQEQHRIQHNSDYS
YPKWFIPNTLKYYVLLHDVSAGDEQRAESIYEEMKQKYGTQGCYLLKINSRTSNRASDEQ
IPDPWSQYLQKNSIQNQESYEDGPCTITSNKNSDNNLLSLDGLDNEVKDGLPNNFRAHPL
QLEQSSDPSNSIDGPDHLRSASSLHETKKGNTGIIHGACLTLTDHDRIRQFIQEFTFRGL
LPHIEKTIRQLNDQLISRKGLSRSLFSATKKWFSGSKVPEKSINDLKNTSGLLYPPEAPE
LQIRKMADLCFLVQHYDLAYSCYHTAKKDFLNDQAMLYAAGALEMAAVSAFLQPGAPRPY
PAHYMDTAIQTYRDICKNMVLAERCVLLSAELLKSQSKYSEAAALLIRLTSEDSDLRSAL
LLEQAAHCFINMKSPMVRKYAFHMILAGHRFSKAGQKKHALRCYCQAMQVYKGKGWSLAE
DHINFTIGRQSYTLRQLDNAVSAFRHILINESKQSAAQQGAFLREYLYVYKNVSQLSPDG
PLPQLPLPYINSSATRVFFGHDRRPADGEKQAATHVSLDQEYDSESSQQWRELEEQVVSV
VNKGVIPSNFHPTQYCLNSYSDNSRFPLAVVEEPITVEVAFRNPLKVLLLLTDLSLLWKF
HPKDFSGKDNEEVKQLVTSEPEMIGAEVISEFLINGEESKVARLKLFPHHIGELHILGVV
YNLGTIQGSMTVDGIGALPGCHTGKYSLSMSVRGKQDLEIQGPRLNNTKEEKTSVKYGPD
RRLDPIITEEMPLLEVFFIHFPTGLLCGEIRKAYVEFVNVSKCPLTGLKVVSKRPEFFTF
GGNTAVLTPLSPSASENCSAYKTVVTDATSVCTALISSASSVDFGIGTGSQPEVIPVPLP
DTVLLPGASVQLPMWLRGPDEEGVHEINFLFYYESVKKQPKIRHRILRHTAIICTSRSLN
VRATVCRSNSLENEEGRGGNMLVFVDVENTNTSEAGVKEFHIVQVSSSSKHWKLQKSVNL
SENKDTKLASREKGKFCFKAIRCEKEEAATQSSEKYTFADIIFGNEQIISSASPCADFFY
RSLSSELKKPQAHLPVHTEKQSTEDAVRLIQKCSEVDLNIVILWKAYVVEDSKQLILEGQ
HHVILRTIGKEAFSYPQKQEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESF
NHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQL
KSQEIHSLQLKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV

Sequence length

1435

Interactions

View interactions

	Reactome
			RAB GEFs exchange GTP for GDP on RABs

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Breast cancer	Malignant neoplasm of breast	rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158 View all (309 more)

TRAPPC8 (trafficking protein particle complex subunit 8)