Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
22862
Gene name Gene Name - the full gene name approved by the HGNC.
Fibronectin type III domain containing 3A
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
FNDC3A
Synonyms (NCBI Gene) Gene synonyms aliases
FNDC3, HUGO, bA203I16.1, bA203I16.5
Chromosome Chromosome number
13
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
13q14.2
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT001631 hsa-let-7b-5p pSILAC 18668040
MIRT023556 hsa-miR-1-3p Microarray 18668037
MIRT023556 hsa-miR-1-3p Proteomics 18668040
MIRT027515 hsa-miR-98-5p Microarray 19088304
MIRT001631 hsa-let-7b-5p Proteomics;Other 18668040
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000139 Component Golgi membrane IEA
GO:0001669 Component Acrosomal vesicle IEA
GO:0003723 Function RNA binding HDA 22658674
GO:0005737 Component Cytoplasm IBA
GO:0005737 Component Cytoplasm IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
615794 20296 ENSG00000102531
Protein
UniProt ID Q9Y2H6
Protein name Fibronectin type-III domain-containing protein 3A (Human gene expressed in odontoblasts)
Protein function Mediates spermatid-Sertoli adhesion during spermatogenesis.
PDB 1WK0 , 1X3D , 1X4X , 1X5X , 2CRM , 2CRZ
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00041 fn3 267 359 Fibronectin type III domain Domain
PF00041 fn3 372 455 Fibronectin type III domain Domain
PF00041 fn3 468 552 Fibronectin type III domain Domain
PF00041 fn3 567 650 Fibronectin type III domain Domain
PF00041 fn3 667 747 Fibronectin type III domain Domain
PF00041 fn3 760 841 Fibronectin type III domain Domain
PF00041 fn3 865 940 Fibronectin type III domain Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in the odontoblast and nerves in the dental pulp. Also expressed in trachea and to a lesser extent in the brain, liver, lung and kidney. {ECO:0000269|PubMed:18218838}.
Sequence
MAEHPPLLDTTQILSSDISLLSAPIVSADGTQQVILVQVNPGEAFTIRREDGQFQCITGP
AQVPMMSPNGSVPPIYVPPGYAPQVIEDNGVRRVVVVPQAPEFHPGSHTVLHRSPHPPLP
GFIPVPTMMPPPPRHMYSPVTGAGDMTTQYMPQYQSSQVYGDVDAHSTHGRSNFRDERSS
KTYERLQKKLKDRQGTQKDKMSSPPSSPQKCPSPINEHNGLIKGQIAGGINTGSAKIKSG
KGKGGTQVDTEIEEKDEETKAFEALLSNIVKPVASDIQARTVVLTWSPPSSLINGETDES
SVPELYGYEVLISSTGKDGKYKSVYVGEETNITLNDLKPAMDYHAKVQAEYNSIKGTPS
E
AEIFTTLSCEPDIPNPPRIANRTKNSLTLQWKAPSDNGSKIQNFVLEWDEGKGNGEFCQC
YMGSQKQFKITKLSPAMGCKFRLSARNDYGTSGFS
EEVLYYTSGCAPSMPASPVLTKAGI
TWLSLQWSKPSGTPSDEGISYILEMEEETSGYGFKPKYDGEDLAYTVKNLRRSTKYKFKV
IAYNSEGKSNPS
EVVEFTTCPDKPGIPVKPSVKGKIHSHSFKITWDPPKDNGGATINKYV
VEMAEGSNGNKWEMIYSGATREHLCDRLNPGCFYRLRVYCISDGGQSAVS
ESLLVQTPAV
PPGPCLPPRLQGRPKAKEIQLRWGPPLVDGGSPISCYSVEMSPIEKDEPREVYQGSEVEC
TVSSLLPGKTYSFRLRAANKMGFGPFS
EKCDITTAPGPPDQCKPPQVTCRSATCAQVNWE
VPLSNGTDVTEYRLEWGGVEGSMQICYCGPGLSYEIKGLSPATTYYCRVQALSVVGAGPF
S
EVVACVTPPSVPGIVTCLQEISDDEIENPHYSPSTCLAISWEKPCDHGSEILAYSIDFG
DKQSLTVGKVTSYIINNLQPDTTYRIRIQALNSLGAGPFS
HMIKLKTKPLPPDPPRLECV
AFSHQNLKLKWGEGTPKTLSTDSIQYHLQMEDKNGRFVSLYRGPCHTYKVQRLNESTSYK
FCIQACNEAGEGPLSQEYIFTTPKSVPAALKAPKIEKVNDHICEITWECLQPMKGDPVIY
SLQVMLGKDSEFKQIYKGPDSSFRYSSLQLNCEYRFRVCAIRQCQDSLGHQDLVGPYSTT
VLFISQRTEPPASTNRDTVESTRTRRALSDEQCAAVILVLFAFFSILIAFIIQYFVIK
Sequence length 1198
Interactions View interactions
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Crohn Disease Crohn's disease N/A N/A GWAS
Glioblastoma Glioblastoma N/A N/A GWAS
Hypothyroidism Hypothyroidism N/A N/A GWAS
Inflammatory Bowel Disease Inflammatory bowel disease N/A N/A GWAS
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Colorectal Neoplasms Associate 27080994
Infertility Male Associate 32026199
Neoplasms Associate 27080994, 35238908
Stomach Neoplasms Associate 37800836