Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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22853
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Lemur tyrosine kinase 2 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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LMTK2 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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AATYK2, BREK, KPI-2, KPI2, LMR2, PPP1R100, cprk, hBREK |
Chromosome
Chromosome number
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7 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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7q21.3 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This pro |
Causal |
Disease term |
Disease name |
dbSNP ID |
References |
Lung carcinoma |
Large cell carcinoma of lung |
rs1805076, rs121909071, rs121913530, rs112445441, rs121913529, rs121913535, rs121913297, rs121913279, rs104886003, rs397516975, rs11554290, rs121913364, rs121913351, rs121913369, rs121913355, rs121912470, rs121913273, rs121913281, rs121913348, rs727503093, rs121913353, rs397516890, rs397516896, rs121913378, rs397516897, rs397516977, rs397516978, rs397516979, rs397516980, rs397516981, rs397516982, rs121913240, rs17851045, rs397517086, rs121913428, rs397517094, rs397517098, rs397517106, rs121913465, rs397517108, rs397517111, rs397517112, rs397517114, rs397517116, rs1554350366, rs397517127, rs397517200, rs397517202, rs121913283, rs121913370, rs121913357, rs727503106, rs121913238, rs727503108, rs397517040, rs397516976, rs1555618025, rs1057519729, rs1584238193 View all (44 more) |
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Prostate cancer |
Malignant neoplasm of prostate, Prostate carcinoma |
rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 |
18264097, 19767753, 29892016 |
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Unknown |
Disease term |
Disease name |
Evidence |
References |
Source |
Nasopharyngeal carcinoma |
Nasopharyngeal carcinoma |
These data suggest that KAT7 can contribute NPC cell growth and survival through up-regulation of NPC-essential genes. |
20512145 |
ClinVar, CBGDA |
Neuroticism |
Neuroticism |
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GWAS |
Diabetes |
Diabetes |
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GWAS |
Breast Cancer |
Breast Cancer |
Importantly, breast cancer patients bearing PRC2 LOF mutations displayed significantly worse prognosis compared with PRC2 wild-type patients |
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GWAS, CBGDA |
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