LMTK2 (lemur tyrosine kinase 2)
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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22853 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Lemur tyrosine kinase 2 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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LMTK2 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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AATYK2, BREK, KPI-2, KPI2, LMR2, PPP1R100, cprk, hBREK |
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Chromosome
Chromosome number
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7 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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7q21.3 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This pro |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | Q8IWU2 | ||||||||||
| Protein name | Serine/threonine-protein kinase LMTK2 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase 2) (Brain-enriched kinase) (hBREK) (CDK5/p35-regulated kinase) (CPRK) (Kinase/phosphatase/inhibitor 2) (Lemur tyrosine kinase 2) (Serine/threonine-protein kinase KPI | ||||||||||
| Protein function | Phosphorylates PPP1C, phosphorylase b and CFTR. | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Mainly expressed in skeletal muscle, and weakly in brain and pancreas. {ECO:0000269|PubMed:12393858}. | ||||||||||
| Sequence |
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| Sequence length | 1503 | ||||||||||
| Interactions | View interactions | ||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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