PPM1E (protein phosphatase, Mg2+/Mn2+ dependent 1E)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 22843 |
| Gene name | Protein phosphatase, Mg2+/Mn2+ dependent 1E |
| Gene symbol | PPM1E |
| Synonyms (NCBI Gene) |
CAMKPNCaMKP-NPOPX1PP2CHcaMKN
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| Chromosome | 17 |
| Chromosome location | 17q22 |
| Summary | This gene encodes a member of the PPM family of serine/threonine-protein phosphatases. The encoded protein is localized to the nucleus and dephosphorylates and inactivates multiple substrates including serine/threonine-protein kinase PAK 1, 5`-AMP-activat |
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miRNA
miRNA information provided by mirtarbase database.
436
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
21
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q8WY54 | ||||||||||
| Protein name | Protein phosphatase 1E (EC 3.1.3.16) (Ca(2+)/calmodulin-dependent protein kinase phosphatase N) (CaMKP-N) (CaMKP-nucleus) (CaMKN) (Partner of PIX 1) (Partner of PIX-alpha) (Partner of PIXA) | ||||||||||
| Protein function | Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2 (By similarity). Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 755 | ||||||||||
| Interactions | View interactions | ||||||||||