Gene Gene information from NCBI Gene database.
Entrez ID 22841
Gene name RAB11 family interacting protein 2
Gene symbol RAB11FIP2
Synonyms (NCBI Gene)
Rab11-FIP2nRip11
Chromosome 10
Chromosome location 10q26.11
miRNA miRNA information provided by mirtarbase database.
596
miRTarBase ID miRNA Experiments Reference
MIRT002812 hsa-miR-1-3p Microarray 15685193
MIRT020855 hsa-miR-155-5p Reporter assay;Other 20584899
MIRT002812 hsa-miR-1-3p Microarray;Other 15685193
MIRT024655 hsa-miR-215-5p Microarray 19074876
MIRT026543 hsa-miR-192-5p Microarray 19074876
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
31
GO ID Ontology Definition Evidence Reference
GO:0001891 Component Phagocytic cup IBA
GO:0001891 Component Phagocytic cup IDA 30883606
GO:0001891 Component Phagocytic cup IEA
GO:0005515 Function Protein binding IPI 12470645, 16905101, 17082457, 19542231, 26032412, 26496610, 28514442, 29997244, 30883606, 32296183, 32814053, 33961781, 35271311, 36931259
GO:0005654 Component Nucleoplasm IDA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
608599 29152 ENSG00000107560
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q7L804
Protein name Rab11 family-interacting protein 2 (Rab11-FIP2) (NRip11)
Protein function A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membran
PDB 2GZD , 2GZH , 2K6S , 3TSO , 4C4P , 6S8X
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00168 C2 13 122 C2 domain Domain
PF09457 RBD-FIP 452 499 FIP domain Motif
Sequence
MMLSEQAQKWFPTHVQVTVLQAKDLKPKGKSGTNDTYTIIQLGKEKYSTSVAEKTLEPVW
KEEASFELPGLLIQGSPEKYILFLIVMHRSLVGLDKFLGQVAINLNDIFEDKQRRKTEWF
RL
ESKQGKRIKNRGEIKVNIQFMRNNMTASMFDLSMKDKTRSPFAKLKDKMKGRKNDGTF
SDTSSAIIPSTHMPDANSEFSSGEIQMKSKPKKPFLLGPQRLSSAHSMSDLSGSHMSSEK
LKAGTIGQTHLLGHQLDSFGTVPESGSLKSPHRRTLSFDTSKMNQPDSIVDEGELCFGRQ
NDPFTNVTASLPQKFATLPRKKNPFEESSETWDSSMNLFSKPIEIRKENKREKREKVSLF
ERVTGKKDSRRSDKLNNGGSDSPCDLKSPNAFSENRQDYFDYESTNPFTAKFRASNIMPS
SSFHMSPTSNEDLRKIPDSNPFDATAGYRSLTYEEVLQELVKHKELLRRKDTHIRELEDY
IDNLLVRVMEETPSILRVP
YEPSRKAGKFSNS
Sequence length 512
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  Endocytosis   Vasopressin regulates renal water homeostasis via Aquaporins
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
12
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ASTHMA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
BASAL CELL CARCINOMA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
CELIAC DISEASE GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
CHOROIDAL MELANOMA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References Evidence Score
Stomach Neoplasms Associate 36984512
★☆☆☆☆
Found in Text Mining only