COBLL1 (cordon-bleu WH2 repeat protein like 1)

Gene

• Entrez ID: 22837
• Gene name: Cordon-bleu WH2 repeat protein like 1
• Gene symbol: COBLL1
• Synonyms (NCBI Gene): COBLR1
• Chromosome: 2
• Chromosome location: 2q24.3

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT024539	hsa-miR-215-5p	Microarray	19074876
MIRT026290	hsa-miR-192-5p	Microarray	19074876
MIRT030747	hsa-miR-21-5p	Microarray	18591254
MIRT717215	hsa-miR-4694-3p	HITS-CLIP	19536157
MIRT717214	hsa-miR-224-3p	HITS-CLIP	19536157
MIRT717213	hsa-miR-522-3p	HITS-CLIP	19536157
MIRT717212	hsa-miR-200a-5p	HITS-CLIP	19536157
MIRT717211	hsa-miR-200b-5p	HITS-CLIP	19536157
MIRT717210	hsa-miR-600	HITS-CLIP	19536157
MIRT717209	hsa-miR-520d-5p	HITS-CLIP	19536157
MIRT717208	hsa-miR-524-5p	HITS-CLIP	19536157
MIRT717207	hsa-miR-6768-5p	HITS-CLIP	19536157
MIRT717206	hsa-miR-627-3p	HITS-CLIP	19536157
MIRT717205	hsa-miR-4424	HITS-CLIP	19536157
MIRT613875	hsa-miR-8485	HITS-CLIP	23313552
MIRT692429	hsa-miR-329-3p	HITS-CLIP	23313552
MIRT692428	hsa-miR-362-3p	HITS-CLIP	23313552
MIRT692427	hsa-miR-603	HITS-CLIP	23313552
MIRT613874	hsa-miR-3943	HITS-CLIP	23313552
MIRT692426	hsa-miR-6793-3p	HITS-CLIP	23313552
MIRT692425	hsa-miR-3941	HITS-CLIP	23313552
MIRT613875	hsa-miR-8485	HITS-CLIP	23824327
MIRT613874	hsa-miR-3943	HITS-CLIP	23824327
MIRT613875	hsa-miR-8485	HITS-CLIP	23824327
MIRT613874	hsa-miR-3943	HITS-CLIP	23824327
MIRT613875	hsa-miR-8485	HITS-CLIP	23824327
MIRT613874	hsa-miR-3943	HITS-CLIP	23824327
MIRT613875	hsa-miR-8485	HITS-CLIP	23824327
MIRT613874	hsa-miR-3943	HITS-CLIP	23824327
MIRT613874	hsa-miR-3943	HITS-CLIP	27418678
MIRT613875	hsa-miR-8485	HITS-CLIP	27418678
MIRT613875	hsa-miR-8485	HITS-CLIP	27418678
MIRT717215	hsa-miR-4694-3p	HITS-CLIP	19536157
MIRT717214	hsa-miR-224-3p	HITS-CLIP	19536157
MIRT717213	hsa-miR-522-3p	HITS-CLIP	19536157
MIRT717212	hsa-miR-200a-5p	HITS-CLIP	19536157
MIRT717211	hsa-miR-200b-5p	HITS-CLIP	19536157
MIRT717210	hsa-miR-600	HITS-CLIP	19536157
MIRT717209	hsa-miR-520d-5p	HITS-CLIP	19536157
MIRT717208	hsa-miR-524-5p	HITS-CLIP	19536157
MIRT717207	hsa-miR-6768-5p	HITS-CLIP	19536157
MIRT717206	hsa-miR-627-3p	HITS-CLIP	19536157
MIRT717205	hsa-miR-4424	HITS-CLIP	19536157
MIRT613875	hsa-miR-8485	HITS-CLIP	23313552
MIRT692429	hsa-miR-329-3p	HITS-CLIP	23313552
MIRT692428	hsa-miR-362-3p	HITS-CLIP	23313552
MIRT692427	hsa-miR-603	HITS-CLIP	23313552
MIRT613874	hsa-miR-3943	HITS-CLIP	23313552
MIRT692426	hsa-miR-6793-3p	HITS-CLIP	23313552
MIRT692425	hsa-miR-3941	HITS-CLIP	23313552
MIRT613875	hsa-miR-8485	HITS-CLIP	23824327
MIRT613874	hsa-miR-3943	HITS-CLIP	23824327
MIRT613875	hsa-miR-8485	HITS-CLIP	23824327
MIRT613874	hsa-miR-3943	HITS-CLIP	23824327
MIRT613875	hsa-miR-8485	HITS-CLIP	23824327
MIRT613874	hsa-miR-3943	HITS-CLIP	23824327
MIRT613875	hsa-miR-8485	HITS-CLIP	23824327
MIRT613874	hsa-miR-3943	HITS-CLIP	23824327
MIRT902017	hsa-miR-103a	CLIP-seq
MIRT902018	hsa-miR-107	CLIP-seq
MIRT902019	hsa-miR-138	CLIP-seq
MIRT902020	hsa-miR-15a	CLIP-seq
MIRT902021	hsa-miR-15b	CLIP-seq
MIRT902022	hsa-miR-16	CLIP-seq
MIRT902023	hsa-miR-195	CLIP-seq
MIRT902024	hsa-miR-224	CLIP-seq
MIRT902025	hsa-miR-3123	CLIP-seq
MIRT902026	hsa-miR-3168	CLIP-seq
MIRT902027	hsa-miR-3190	CLIP-seq
MIRT902028	hsa-miR-3616-5p	CLIP-seq
MIRT902029	hsa-miR-3647-5p	CLIP-seq
MIRT902030	hsa-miR-3674	CLIP-seq
MIRT902031	hsa-miR-3925-5p	CLIP-seq
MIRT902032	hsa-miR-424	CLIP-seq
MIRT902033	hsa-miR-4272	CLIP-seq
MIRT902034	hsa-miR-4422	CLIP-seq
MIRT902035	hsa-miR-4427	CLIP-seq
MIRT902036	hsa-miR-4490	CLIP-seq
MIRT902037	hsa-miR-4509	CLIP-seq
MIRT902038	hsa-miR-4527	CLIP-seq
MIRT902039	hsa-miR-4670-3p	CLIP-seq
MIRT902040	hsa-miR-4680-3p	CLIP-seq
MIRT902041	hsa-miR-4698	CLIP-seq
MIRT902042	hsa-miR-4732-5p	CLIP-seq
MIRT902043	hsa-miR-4744	CLIP-seq
MIRT902044	hsa-miR-4776-3p	CLIP-seq
MIRT902045	hsa-miR-4795-5p	CLIP-seq
MIRT902046	hsa-miR-4799-5p	CLIP-seq
MIRT902047	hsa-miR-497	CLIP-seq
MIRT902048	hsa-miR-519a	CLIP-seq
MIRT902049	hsa-miR-519b-3p	CLIP-seq
MIRT902050	hsa-miR-519c-3p	CLIP-seq
MIRT902051	hsa-miR-573	CLIP-seq
MIRT902052	hsa-miR-885-5p	CLIP-seq
MIRT1546538	hsa-miR-3647-3p	CLIP-seq
MIRT1546538	hsa-miR-3647-3p	CLIP-seq
MIRT1546538	hsa-miR-3647-3p	CLIP-seq
MIRT1546538	hsa-miR-3647-3p	CLIP-seq
MIRT1546538	hsa-miR-3647-3p	CLIP-seq
MIRT1967575	hsa-miR-1256	CLIP-seq
MIRT1967576	hsa-miR-1827	CLIP-seq
MIRT902024	hsa-miR-224	CLIP-seq
MIRT1967577	hsa-miR-27a	CLIP-seq
MIRT1967578	hsa-miR-27b	CLIP-seq
MIRT1967579	hsa-miR-3074-3p	CLIP-seq
MIRT902025	hsa-miR-3123	CLIP-seq
MIRT1967580	hsa-miR-3128	CLIP-seq
MIRT1967581	hsa-miR-3155	CLIP-seq
MIRT1967582	hsa-miR-3155b	CLIP-seq
MIRT1967583	hsa-miR-3163	CLIP-seq
MIRT1967584	hsa-miR-338-5p	CLIP-seq
MIRT1967585	hsa-miR-3591-3p	CLIP-seq
MIRT1967586	hsa-miR-3662	CLIP-seq
MIRT902030	hsa-miR-3674	CLIP-seq
MIRT902031	hsa-miR-3925-5p	CLIP-seq
MIRT1967587	hsa-miR-3945	CLIP-seq
MIRT1967588	hsa-miR-4253	CLIP-seq
MIRT1967589	hsa-miR-4305	CLIP-seq
MIRT1967590	hsa-miR-4310	CLIP-seq
MIRT1967591	hsa-miR-4438	CLIP-seq
MIRT1967592	hsa-miR-4477b	CLIP-seq
MIRT1967593	hsa-miR-4504	CLIP-seq
MIRT1967594	hsa-miR-4652-3p	CLIP-seq
MIRT1967595	hsa-miR-4720-5p	CLIP-seq
MIRT902042	hsa-miR-4732-5p	CLIP-seq
MIRT1967596	hsa-miR-4799-3p	CLIP-seq
MIRT1967597	hsa-miR-484	CLIP-seq
MIRT1967598	hsa-miR-5096	CLIP-seq
MIRT1967599	hsa-miR-513a-5p	CLIP-seq
MIRT1967600	hsa-miR-542-3p	CLIP-seq
MIRT1967601	hsa-miR-579	CLIP-seq
MIRT1967602	hsa-miR-944	CLIP-seq
MIRT902024	hsa-miR-224	CLIP-seq
MIRT1546538	hsa-miR-3647-3p	CLIP-seq
MIRT1967581	hsa-miR-3155	CLIP-seq
MIRT1967582	hsa-miR-3155b	CLIP-seq
MIRT1967585	hsa-miR-3591-3p	CLIP-seq
MIRT1967591	hsa-miR-4438	CLIP-seq
MIRT1967597	hsa-miR-484	CLIP-seq
MIRT1967602	hsa-miR-944	CLIP-seq
MIRT1967577	hsa-miR-27a	CLIP-seq
MIRT1967578	hsa-miR-27b	CLIP-seq
MIRT1967590	hsa-miR-4310	CLIP-seq
MIRT1967592	hsa-miR-4477b	CLIP-seq
MIRT1967593	hsa-miR-4504	CLIP-seq
MIRT1967594	hsa-miR-4652-3p	CLIP-seq
MIRT1967598	hsa-miR-5096	CLIP-seq
MIRT1967599	hsa-miR-513a-5p	CLIP-seq
MIRT1967600	hsa-miR-542-3p	CLIP-seq
MIRT1967602	hsa-miR-944	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003779	Function	Actin binding	IEA
GO:0003785	Function	Actin monomer binding	IEA
GO:0005515	Function	Protein binding	IPI	20936779, 33961781
GO:0005938	Component	Cell cortex	IEA
GO:0016020	Component	Membrane	IEA
GO:0045296	Function	Cadherin binding	HDA	25468996
GO:0070062	Component	Extracellular exosome	HDA	19056867

Other IDs

• MIM: 610318
• HGNC: 23571
• e!Ensembl: ENSG00000082438

Protein

• UniProt ID: Q53SF7
• Protein name: Cordon-bleu protein-like 1
• PDB: 2DAJ
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF09469	Cobl	136 → 227	Cordon-bleu ubiquitin-like domain	Domain

• Sequence:

  MDGRTPRPQDAPARRKPKAKAPLPPAETKYTDVSSAADSVESTAFIMEQKENMIDKDVEL
  SVVLPGDIIKSTTVHGSKPMMDLLIFLCAQYHLNPSSYTIDLLSAEQNHIKFKPNTPIGM
  LEVEKVILKPKMLDKKKPTPIIPEKTVRVVINFKKTQKTIVRVSPHASLQELAPIICSKC
  EFDPLHTLLLKDYQSQEPLDLTKSLNDLGLRELYAMDVNRESCQISQNLDIMKEKENKGF
  FSFFQRSKKKRDQTASAPATPLVNKHRPTFTRSNTISKPYISNTLPSDAPKKRRAPLPPM
  PASQSVPQDLAHIQERPASCIVKSMSVDETDKSPCEAGRVRAGSLQLSSMSAGNSSLRRT
  KRKAPSPPSKIPPHQSDENSRVTALQPVDGVPPDSASEANSPEELSSPAGISSDYSLEEI
  DEKEELSEVPKVEAENISPKSQDIPFVSTDIINTLKNDPDSALGNGSGEFSQNSMEEKQE
  TKSTDGQEPHSVVYDTSNGKKVVDSIRNLKSLGPNQENVVQNEIIVYPENTEDNMKNGVK
  KTEINVEGVAKNNNIDMEVERPSNSEAHETDTAISYKENHLAASSVPDQKLNQPSAEKTK
  DAAIQTTPSCNSFDGKHQDHNLSDSKVEECVQTSNNNISTQHSCLSSQDSVNTSREFRSQ
  GTLIIHSEDPLTVKDPICAHGNDDLLPPVDRIDKNSTASYLKNYPLYRQDYNPKPKPSNE
  ITREYIPKIGMTTYKIVPPKSLEISKDWQSETIEYKDDQDMHALGKKHTHENVKETAIQT
  EDSAISESPEEPLPNLKPKPNLRTEHQVPSSVSSPDDAMVSPLKPAPKMTRDTGTAPFAP
  NLEEINNILESKFKSRASNAQAKPSSFFLQMQKRVSGHYVTSAAAKSVHAAPNPAPKELT
  NKEAERDMLPSPEQTLSPLSKMPHSVPQPLVEKTDDDVIGQAPAEASPPPIAPKPVTIPA
  SQVSTQNLKTLKTFGAPRPYSSSGPSPFALAVVKRSQSFSKERTESPSASALVQPPANTE
  EGKTHSVNKFVDIPQLGVSDKENNSAHNEQNSQIPTPTDGPSFTVMRQSSLTFQSSDPEQ
  MRQSLLTAIRSGEAAAKLKRVTIPSNTISVNGRSRLSHSMSPDAQDGH

• Sequence length: 1128