Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
22834
Gene name Gene Name - the full gene name approved by the HGNC.
Zinc finger protein 652
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ZNF652
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
17q21.32-q21.33
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT000975 hsa-miR-155-5p Luciferase reporter assay 18367535
MIRT000975 hsa-miR-155-5p Luciferase reporter assay 18367535
MIRT000975 hsa-miR-155-5p Reporter assay;Other 20584899
MIRT021105 hsa-miR-186-5p Sequencing 20371350
MIRT021763 hsa-miR-132-3p Microarray 17612493
Transcription factors
Transcription factor Regulation Reference
CBFA2T3 Repression 20116376
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000978 Function RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA 21873635
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific IBA 21873635
GO:0005515 Function Protein binding IPI 16966434
GO:0005634 Component Nucleus IBA 21873635
GO:0006357 Process Regulation of transcription by RNA polymerase II IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
613907 29147 ENSG00000198740
Protein
UniProt ID Q9Y2D9
Protein name Zinc finger protein 652
Protein function Functions as a transcriptional repressor.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00096 zf-C2H2 245 268 Zinc finger, C2H2 type Domain
PF12874 zf-met 329 351 Domain
PF00096 zf-C2H2 357 379 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 385 407 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 441 463 Zinc finger, C2H2 type Domain
Tissue specificity TISSUE SPECIFICITY: Widely expressed with higher expression in breast, prostate, vulva and pancreas. {ECO:0000269|PubMed:16966434}.
Sequence
MSHTASSCQELVENCAVHVAGMAQEDSRRGQVPSSFYHGANQELDLSTKVYKRESGSPYS
VLVDTKMSKPHLHETEEQPYFRETRAVSDVHAVKEDRENSDDTEEEEEEVSYKREQIIVE
VNLNNQTLNVSKGEKGVSSQSKETPVLKTSSEEEEEESEEEATDDSNDYGENEKQKKKEK
IVEKVSVTQRRTRRAASVAAATTSPTPRTTRGRRKSVEPPKRKKRATKEPKAPVQKAKCE
EKETLTCEKCPRVFNTRWYLEKHMNVTHRRMQICDKCGKKFVLESELSLHQQTDCEKNIQ
CVSCNKSFKKLWSLHEHIKIVHGYAEKKFSCEICEKKFYTMAHVRKHMVAHTKDMPFTCE
TCGKSFKRSMSLKVHSLQH
SGEKPFRCENCDERFQYKYQLRSHMSIHIGHKQFMCQWCGK
DFNMKQYFDEHMKTHTGEKPFICEICGKSFTSRPNMKRHRRTHTGEKPYPCDVCGQRFRF
SNMLKAHKEKCFRVTSPVNVPPAVQIPLTTSPATPVPSVVNTATTPTPPINMNPVSTLPP
RPIPHPFSHLHIHPHPHHPHHLPIPPVPHLPPPPALFKSEPLNHRGQSEDNFLRHLAEKN
SSAQHH
Sequence length 606
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Coronary artery disease Coronary Artery Disease rs137852988, rs121918313, rs121918529, rs121918531, rs137852340, rs1555800701, rs1215189537 29212778
Prostate cancer Malignant neoplasm of prostate, Prostate carcinoma rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 21602798
Unknown
Disease term Disease name Evidence References Source
Asthma Asthma 30552067 ClinVar, GWAS
Eczema Eczema GWAS
Bipolar Disorder Bipolar Disorder GWAS
Alzheimer disease Alzheimer disease GWAS
Associations from Text Mining
Disease Name Relationship Type References
Alzheimer Disease Associate 39201500
Breast Neoplasms Associate 37906592
Carcinogenesis Associate 35258403
Coronary Artery Disease Associate 39201500
Dermatitis Atopic Associate 29489655
Diabetic Nephropathies Associate 32778679
Egg Hypersensitivity Associate 29489655
Food Hypersensitivity Associate 29489655
Glioblastoma Associate 35258403
Hypertension Associate 19430483