NKAPL (NFKB activating protein like)

Gene

• Entrez ID: 222698
• Gene name: NFKB activating protein like
• Gene symbol: NKAPL
• Synonyms (NCBI Gene): C6orf194, bA424I5.1
• Chromosome: 6
• Chromosome location: 6p22.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT663507	hsa-miR-873-3p	HITS-CLIP	23313552
MIRT684694	hsa-miR-6867-5p	HITS-CLIP	23313552
MIRT663506	hsa-miR-3672	HITS-CLIP	23313552
MIRT663505	hsa-miR-6864-3p	HITS-CLIP	23313552
MIRT663504	hsa-miR-6818-5p	HITS-CLIP	23313552
MIRT684693	hsa-miR-574-5p	HITS-CLIP	23313552
MIRT663507	hsa-miR-873-3p	HITS-CLIP	23824327
MIRT663506	hsa-miR-3672	HITS-CLIP	23824327
MIRT663505	hsa-miR-6864-3p	HITS-CLIP	23824327
MIRT663504	hsa-miR-6818-5p	HITS-CLIP	23824327
MIRT663506	hsa-miR-3672	HITS-CLIP	27418678
MIRT663506	hsa-miR-3672	HITS-CLIP	27418678
MIRT663506	hsa-miR-3672	HITS-CLIP	27418678
MIRT663506	hsa-miR-3672	HITS-CLIP	27418678
MIRT684693	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT684693	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT684693	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT684693	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT663504	hsa-miR-6818-5p	HITS-CLIP	27418678
MIRT663504	hsa-miR-6818-5p	HITS-CLIP	27418678
MIRT663504	hsa-miR-6818-5p	HITS-CLIP	27418678
MIRT663504	hsa-miR-6818-5p	HITS-CLIP	27418678
MIRT663505	hsa-miR-6864-3p	HITS-CLIP	27418678
MIRT663505	hsa-miR-6864-3p	HITS-CLIP	27418678
MIRT663505	hsa-miR-6864-3p	HITS-CLIP	27418678
MIRT663505	hsa-miR-6864-3p	HITS-CLIP	27418678
MIRT684694	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT684694	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT684694	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT684694	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT663507	hsa-miR-873-3p	HITS-CLIP	27418678
MIRT663507	hsa-miR-873-3p	HITS-CLIP	27418678
MIRT663507	hsa-miR-873-3p	HITS-CLIP	27418678
MIRT663507	hsa-miR-873-3p	HITS-CLIP	27418678
MIRT663507	hsa-miR-873-3p	HITS-CLIP	23313552
MIRT684694	hsa-miR-6867-5p	HITS-CLIP	23313552
MIRT663506	hsa-miR-3672	HITS-CLIP	23313552
MIRT663505	hsa-miR-6864-3p	HITS-CLIP	23313552
MIRT663504	hsa-miR-6818-5p	HITS-CLIP	23313552
MIRT684693	hsa-miR-574-5p	HITS-CLIP	23313552
MIRT663507	hsa-miR-873-3p	HITS-CLIP	23824327
MIRT663506	hsa-miR-3672	HITS-CLIP	23824327
MIRT663505	hsa-miR-6864-3p	HITS-CLIP	23824327
MIRT663504	hsa-miR-6818-5p	HITS-CLIP	23824327
MIRT1186069	hsa-miR-19a	CLIP-seq
MIRT1186070	hsa-miR-19b	CLIP-seq
MIRT1186071	hsa-miR-3074-5p	CLIP-seq
MIRT1186072	hsa-miR-320e	CLIP-seq
MIRT1186073	hsa-miR-3613-3p	CLIP-seq
MIRT1186074	hsa-miR-370	CLIP-seq
MIRT1186075	hsa-miR-4282	CLIP-seq
MIRT1186076	hsa-miR-4744	CLIP-seq
MIRT1186077	hsa-miR-495	CLIP-seq
MIRT1186078	hsa-miR-548aa	CLIP-seq
MIRT2283122	hsa-miR-4772-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003682	Function	Chromatin binding	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0007283	Process	Spermatogenesis	IEA
GO:0010468	Process	Regulation of gene expression	IBA
GO:0030154	Process	Cell differentiation	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q5M9Q1
• Protein name: NKAP-like protein
• Protein function: Transcriptional repressor of Notch-mediated signaling. Required for spermatogenesis.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF15692	NKAP	109 → 204		Family
  PF06047	Nkap_C	293 → 394	NF-kappa-B-activating protein C-terminal domain	Domain

• Sequence:

  MPPVSRSSYSEDIVGSRRRRRSSSGSPPSPQSRCSSWDGCSRSHSRGREGLRPPWSELDV
  GALYPFSRSGSRGRLPRFRNYAFASSWSTSYSGYRYHRHCYAEERQSAEDYEKEESHRQR
  RLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSSSDSNSEEHRKKKT
  SRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKK
  NKKTKKESSDSSCKDSEEDLSEATWMEQPNVADTMDLIGPEAPIIHTSQDEKPLKYGHAL
  LPGEGAAMAEYVKAGKRIPRRGEIGLTSEEIGSFECSGYVMSGSRHRRMEAVRLRKENQI
  YSADEKRALASFNQEERRKRESKILASFREMVHKKTKEKDDK

• Sequence length: 402