Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	222256
Gene name Gene Name - the full gene name approved by the HGNC.	Cadherin related family member 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	CDHR3
Synonyms (NCBI Gene) Gene synonyms aliases	CDH28
Chromosome Chromosome number	7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	7q22.3

Show/Hide all(206)

miRTarBase ID	miRNA	Experiments	Reference
MIRT043326	hsa-miR-331-3p	CLASH	23622248
MIRT880028	hsa-miR-1178	CLIP-seq
MIRT880029	hsa-miR-1200	CLIP-seq
MIRT880030	hsa-miR-1224-3p	CLIP-seq
MIRT880031	hsa-miR-1245b-3p	CLIP-seq
MIRT880032	hsa-miR-1253	CLIP-seq
MIRT880033	hsa-miR-125a-3p	CLIP-seq
MIRT880034	hsa-miR-1273f	CLIP-seq
MIRT880035	hsa-miR-129-5p	CLIP-seq
MIRT880036	hsa-miR-1343	CLIP-seq
MIRT880037	hsa-miR-1913	CLIP-seq
MIRT880038	hsa-miR-197	CLIP-seq
MIRT880039	hsa-miR-27a	CLIP-seq
MIRT880040	hsa-miR-27b	CLIP-seq
MIRT880041	hsa-miR-3117-5p	CLIP-seq
MIRT880042	hsa-miR-3140-3p	CLIP-seq
MIRT880043	hsa-miR-3149	CLIP-seq
MIRT880044	hsa-miR-3152-5p	CLIP-seq
MIRT880045	hsa-miR-3156-3p	CLIP-seq
MIRT880046	hsa-miR-3187-3p	CLIP-seq
MIRT880047	hsa-miR-323-3p	CLIP-seq
MIRT880048	hsa-miR-324-3p	CLIP-seq
MIRT880049	hsa-miR-338-3p	CLIP-seq
MIRT880050	hsa-miR-3545-3p	CLIP-seq
MIRT880051	hsa-miR-3663-5p	CLIP-seq
MIRT880052	hsa-miR-371-5p	CLIP-seq
MIRT880053	hsa-miR-371b-5p	CLIP-seq
MIRT880054	hsa-miR-3934	CLIP-seq
MIRT880055	hsa-miR-3938	CLIP-seq
MIRT880056	hsa-miR-411	CLIP-seq
MIRT880057	hsa-miR-4274	CLIP-seq
MIRT880058	hsa-miR-4301	CLIP-seq
MIRT880059	hsa-miR-4317	CLIP-seq
MIRT880060	hsa-miR-4324	CLIP-seq
MIRT880061	hsa-miR-4419a	CLIP-seq
MIRT880062	hsa-miR-4435	CLIP-seq
MIRT880063	hsa-miR-4506	CLIP-seq
MIRT880064	hsa-miR-450b-5p	CLIP-seq
MIRT880065	hsa-miR-4510	CLIP-seq
MIRT880066	hsa-miR-4519	CLIP-seq
MIRT880067	hsa-miR-4530	CLIP-seq
MIRT880068	hsa-miR-4635	CLIP-seq
MIRT880069	hsa-miR-4659a-5p	CLIP-seq
MIRT880070	hsa-miR-4659b-5p	CLIP-seq
MIRT880071	hsa-miR-4680-5p	CLIP-seq
MIRT880072	hsa-miR-4701-5p	CLIP-seq
MIRT880073	hsa-miR-4716-5p	CLIP-seq
MIRT880074	hsa-miR-4727-5p	CLIP-seq
MIRT880075	hsa-miR-4729	CLIP-seq
MIRT880076	hsa-miR-4753-3p	CLIP-seq
MIRT880077	hsa-miR-4755-3p	CLIP-seq
MIRT880078	hsa-miR-4763-5p	CLIP-seq
MIRT880079	hsa-miR-4776-3p	CLIP-seq
MIRT880080	hsa-miR-4781-3p	CLIP-seq
MIRT880081	hsa-miR-498	CLIP-seq
MIRT880082	hsa-miR-507	CLIP-seq
MIRT880083	hsa-miR-5095	CLIP-seq
MIRT880084	hsa-miR-5096	CLIP-seq
MIRT880085	hsa-miR-513a-5p	CLIP-seq
MIRT880086	hsa-miR-518a-5p	CLIP-seq
MIRT880087	hsa-miR-520d-5p	CLIP-seq
MIRT880088	hsa-miR-524-5p	CLIP-seq
MIRT880089	hsa-miR-527	CLIP-seq
MIRT880090	hsa-miR-544b	CLIP-seq
MIRT880091	hsa-miR-548s	CLIP-seq
MIRT880092	hsa-miR-550a	CLIP-seq
MIRT880093	hsa-miR-552	CLIP-seq
MIRT880094	hsa-miR-557	CLIP-seq
MIRT880095	hsa-miR-580	CLIP-seq
MIRT880096	hsa-miR-588	CLIP-seq
MIRT880097	hsa-miR-640	CLIP-seq
MIRT880098	hsa-miR-764	CLIP-seq
MIRT880099	hsa-miR-766	CLIP-seq
MIRT880100	hsa-miR-885-5p	CLIP-seq
MIRT880101	hsa-miR-891b	CLIP-seq
MIRT880033	hsa-miR-125a-3p	CLIP-seq
MIRT880038	hsa-miR-197	CLIP-seq
MIRT880046	hsa-miR-3187-3p	CLIP-seq
MIRT880051	hsa-miR-3663-5p	CLIP-seq
MIRT880052	hsa-miR-371-5p	CLIP-seq
MIRT880053	hsa-miR-371b-5p	CLIP-seq
MIRT880054	hsa-miR-3934	CLIP-seq
MIRT880062	hsa-miR-4435	CLIP-seq
MIRT880072	hsa-miR-4701-5p	CLIP-seq
MIRT880073	hsa-miR-4716-5p	CLIP-seq
MIRT880077	hsa-miR-4755-3p	CLIP-seq
MIRT880080	hsa-miR-4781-3p	CLIP-seq
MIRT880084	hsa-miR-5096	CLIP-seq
MIRT880091	hsa-miR-548s	CLIP-seq
MIRT880096	hsa-miR-588	CLIP-seq
MIRT880097	hsa-miR-640	CLIP-seq
MIRT880098	hsa-miR-764	CLIP-seq
MIRT880029	hsa-miR-1200	CLIP-seq
MIRT880033	hsa-miR-125a-3p	CLIP-seq
MIRT880036	hsa-miR-1343	CLIP-seq
MIRT1960748	hsa-miR-182	CLIP-seq
MIRT880038	hsa-miR-197	CLIP-seq
MIRT1960749	hsa-miR-2115	CLIP-seq
MIRT1960750	hsa-miR-216a	CLIP-seq
MIRT1960751	hsa-miR-31	CLIP-seq
MIRT880044	hsa-miR-3152-5p	CLIP-seq
MIRT880046	hsa-miR-3187-3p	CLIP-seq
MIRT880051	hsa-miR-3663-5p	CLIP-seq
MIRT880052	hsa-miR-371-5p	CLIP-seq
MIRT880053	hsa-miR-371b-5p	CLIP-seq
MIRT1960752	hsa-miR-375	CLIP-seq
MIRT880054	hsa-miR-3934	CLIP-seq
MIRT1960753	hsa-miR-3976	CLIP-seq
MIRT880060	hsa-miR-4324	CLIP-seq
MIRT880062	hsa-miR-4435	CLIP-seq
MIRT1960754	hsa-miR-4438	CLIP-seq
MIRT880072	hsa-miR-4701-5p	CLIP-seq
MIRT880073	hsa-miR-4716-5p	CLIP-seq
MIRT880074	hsa-miR-4727-5p	CLIP-seq
MIRT1960755	hsa-miR-4731-5p	CLIP-seq
MIRT1960756	hsa-miR-4733-5p	CLIP-seq
MIRT880076	hsa-miR-4753-3p	CLIP-seq
MIRT880077	hsa-miR-4755-3p	CLIP-seq
MIRT1960757	hsa-miR-4775	CLIP-seq
MIRT880080	hsa-miR-4781-3p	CLIP-seq
MIRT880081	hsa-miR-498	CLIP-seq
MIRT880083	hsa-miR-5095	CLIP-seq
MIRT880084	hsa-miR-5096	CLIP-seq
MIRT1960758	hsa-miR-512-3p	CLIP-seq
MIRT880090	hsa-miR-544b	CLIP-seq
MIRT880091	hsa-miR-548s	CLIP-seq
MIRT880093	hsa-miR-552	CLIP-seq
MIRT880096	hsa-miR-588	CLIP-seq
MIRT1960759	hsa-miR-590-3p	CLIP-seq
MIRT880097	hsa-miR-640	CLIP-seq
MIRT1960760	hsa-miR-759	CLIP-seq
MIRT880098	hsa-miR-764	CLIP-seq
MIRT880028	hsa-miR-1178	CLIP-seq
MIRT880029	hsa-miR-1200	CLIP-seq
MIRT2197413	hsa-miR-122	CLIP-seq
MIRT2197414	hsa-miR-1255a	CLIP-seq
MIRT2197415	hsa-miR-1255b	CLIP-seq
MIRT880033	hsa-miR-125a-3p	CLIP-seq
MIRT880036	hsa-miR-1343	CLIP-seq
MIRT1960750	hsa-miR-216a	CLIP-seq
MIRT2197416	hsa-miR-3135b	CLIP-seq
MIRT880044	hsa-miR-3152-5p	CLIP-seq
MIRT2197417	hsa-miR-3157-3p	CLIP-seq
MIRT2197418	hsa-miR-3652	CLIP-seq
MIRT880051	hsa-miR-3663-5p	CLIP-seq
MIRT2197419	hsa-miR-3691-5p	CLIP-seq
MIRT880052	hsa-miR-371-5p	CLIP-seq
MIRT880053	hsa-miR-371b-5p	CLIP-seq
MIRT2197420	hsa-miR-3919	CLIP-seq
MIRT880054	hsa-miR-3934	CLIP-seq
MIRT2197421	hsa-miR-412	CLIP-seq
MIRT2197422	hsa-miR-4305	CLIP-seq
MIRT880059	hsa-miR-4317	CLIP-seq
MIRT880060	hsa-miR-4324	CLIP-seq
MIRT2197423	hsa-miR-4430	CLIP-seq
MIRT2197424	hsa-miR-4436a	CLIP-seq
MIRT1960754	hsa-miR-4438	CLIP-seq
MIRT880064	hsa-miR-450b-5p	CLIP-seq
MIRT2197425	hsa-miR-4700-3p	CLIP-seq
MIRT880074	hsa-miR-4727-5p	CLIP-seq
MIRT1960755	hsa-miR-4731-5p	CLIP-seq
MIRT880076	hsa-miR-4753-3p	CLIP-seq
MIRT880077	hsa-miR-4755-3p	CLIP-seq
MIRT2197426	hsa-miR-4756-3p	CLIP-seq
MIRT880078	hsa-miR-4763-5p	CLIP-seq
MIRT2197427	hsa-miR-4797-5p	CLIP-seq
MIRT880081	hsa-miR-498	CLIP-seq
MIRT880083	hsa-miR-5095	CLIP-seq
MIRT1960758	hsa-miR-512-3p	CLIP-seq
MIRT880086	hsa-miR-518a-5p	CLIP-seq
MIRT880089	hsa-miR-527	CLIP-seq
MIRT880090	hsa-miR-544b	CLIP-seq
MIRT880092	hsa-miR-550a	CLIP-seq
MIRT880093	hsa-miR-552	CLIP-seq
MIRT2197428	hsa-miR-579	CLIP-seq
MIRT2197429	hsa-miR-587	CLIP-seq
MIRT880097	hsa-miR-640	CLIP-seq
MIRT1960760	hsa-miR-759	CLIP-seq
MIRT880098	hsa-miR-764	CLIP-seq
MIRT2197430	hsa-miR-873	CLIP-seq
MIRT2197431	hsa-miR-874	CLIP-seq
MIRT880101	hsa-miR-891b	CLIP-seq
MIRT2197432	hsa-miR-938	CLIP-seq
MIRT2197428	hsa-miR-579	CLIP-seq
MIRT2197429	hsa-miR-587	CLIP-seq
MIRT880033	hsa-miR-125a-3p	CLIP-seq
MIRT880036	hsa-miR-1343	CLIP-seq
MIRT1960750	hsa-miR-216a	CLIP-seq
MIRT880054	hsa-miR-3934	CLIP-seq
MIRT880074	hsa-miR-4727-5p	CLIP-seq
MIRT880081	hsa-miR-498	CLIP-seq
MIRT1960758	hsa-miR-512-3p	CLIP-seq
MIRT880097	hsa-miR-640	CLIP-seq
MIRT1960760	hsa-miR-759	CLIP-seq
MIRT880098	hsa-miR-764	CLIP-seq
MIRT880101	hsa-miR-891b	CLIP-seq
MIRT880033	hsa-miR-125a-3p	CLIP-seq
MIRT1960750	hsa-miR-216a	CLIP-seq
MIRT880054	hsa-miR-3934	CLIP-seq
MIRT1960754	hsa-miR-4438	CLIP-seq
MIRT1960755	hsa-miR-4731-5p	CLIP-seq
MIRT880083	hsa-miR-5095	CLIP-seq
MIRT1960758	hsa-miR-512-3p	CLIP-seq
MIRT880097	hsa-miR-640	CLIP-seq
MIRT1960760	hsa-miR-759	CLIP-seq
MIRT880098	hsa-miR-764	CLIP-seq

Show/Hide all(20)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000902	Process	Cell morphogenesis	IBA
GO:0001618	Function	Virus receptor activity	IEA
GO:0005509	Function	Calcium ion binding	IEA
GO:0005515	Function	Protein binding	IPI	32296183, 32814053
GO:0005886	Component	Plasma membrane	IDA	24241537
GO:0005886	Component	Plasma membrane	IEA
GO:0005912	Component	Adherens junction	IBA
GO:0007043	Process	Cell-cell junction assembly	IBA
GO:0007155	Process	Cell adhesion	IEA
GO:0007156	Process	Homophilic cell adhesion via plasma membrane adhesion molecules	IEA
GO:0008013	Function	Beta-catenin binding	IBA
GO:0016020	Component	Membrane	IEA
GO:0016339	Process	Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	IBA
GO:0016342	Component	Catenin complex	IBA
GO:0016477	Process	Cell migration	IBA
GO:0034332	Process	Adherens junction organization	IBA
GO:0044331	Process	Cell-cell adhesion mediated by cadherin	IBA
GO:0045296	Function	Cadherin binding	IBA
GO:0046718	Process	Symbiont entry into host cell	IEA
GO:0098609	Process	Cell-cell adhesion	IEA

MIM	HGNC	e!Ensembl
615610	26308	ENSG00000128536

Protein

UniProt ID

Q6ZTQ4

Protein name

Cadherin-related family member 3 (Cadherin-like protein 28)

Protein function

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.; (Microbial infe

PDB

6PPO , 6PSF , 7KNV

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00028	Cadherin	141 → 227	Cadherin domain	Domain
PF00028	Cadherin	241 → 336	Cadherin domain	Domain
PF00028	Cadherin	466 → 557	Cadherin domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in bronchial epithelium from adults and in fetal lung tissue. {ECO:0000269|PubMed:24241537}.

Sequence

MQEAIILLALLGAMSGGEALHLILLPATGNVAENSPPGTSVHKFSVKLSASLSPVIPGFP
QIVNSNPLTEAFRVNWLSGTYFEVVTTGMEQLDFETGPNIFDLQIYVKDEVGVTDLQVLT
VQVTDVNEPPQFQGNLAEGLHLYIVERANPGFIYQVEAFDPEDTSRNIPLSYFLISPPKS
FRMSANGTLFSTTELDFEAGHRSFHLIVEVRDSGGLKASTELQVNIVNLNDEVPRFTSPT
RVYTVLEELSPGTIVANITAEDPDDEGFPSHLLYSITTVSKYFMINQLTGTIQVAQRIDR
DAGELRQNPTISLEVLVKDRPYGGQENRIQITFIVEDVNDNPATCQKFTFSIMVPERTAK
GTLLLDLNKFCFDDDSEAPNNRFNFTMPSGVGSGSRFLQDPAGSGKIVLIGDLDYENPSN
LAAGNKYTVIIQVQDVAPPYYKNNVYVYILTSPENEFPLIFDRPSYVFDVSERRPARTRV
GQVRATDKDLPQSSLLYSISTGGASLQYPNVFWINPKTGELQLVTKVDCETTPIYILRIQ
ATNNEDTSSVTVTVNILEENDEKPICTPNSYFLALPVDLKVGTNIQNFKLTCTDLDSSPR
SFRYSIGPGNVNNHFTFSPNAGSNVTRLLLTSRFDYAGGFDKIWDYKLLVYVTDDNLMSD
RKKAEALVETGTVTLSIKVIPHPTTIITTTPRPRVTYQVLRKNVYSPSAWYVPFVITLGS
ILLLGLLVYLVVLLAKAIHRHCPCKTGKNKEPLTKKGETKTAERDVVVETIQMNTIFDGE
AIDPVTGETYEFNSKTGARKWKDPLTQMPKWKESSHQGAAPRRVTAGEGMGSLRSANWEE
DELSGKAWAEDAGLGSRNEGGKLGNPKNRNPAFMNRAYPKPHPGK

Sequence length

885

Interactions

View interactions

Show/Hide Unknown Diseases (4)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Asthma	Asthma (childhood onset), Asthma	N/A	N/A	GWAS
Atrial Fibrillation	Atrial fibrillation	N/A	N/A	GWAS
Crohn Disease	Crohn's disease (indolent vs progressive)	N/A	N/A	GWAS
Multiple Sclerosis	Multiple sclerosis	N/A	N/A	GWAS

Show/Hide Text Mining Associations (12)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Allergic Fungal Sinusitis	Associate	27923563
Asthma	Associate	25848009, 26119467, 28318885, 29121479, 30532249, 30916989, 30930175, 31841129, 33213402, 35050846, 36967681
Ben Ari Shuper Mimouni syndrome	Associate	36967681
Drug Hypersensitivity	Associate	35123074
Ige Responsiveness Atopic	Associate	28318885, 30584054
Infections	Associate	25848009, 27743961, 30916989, 30930175, 31841129, 36967681
Infections	Inhibit	30532249
Neoplasms	Associate	28072738
Otitis Media	Associate	36167494
Respiratory Sounds	Associate	25848009, 28318885, 35050846
Respiratory Tract Diseases	Associate	29121479
Respiratory Tract Infections	Associate	29121479, 36967681

CDHR3 (cadherin related family member 3)