Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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221981
|
Gene name
Gene Name - the full gene name approved by the HGNC.
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Thrombospondin type 1 domain containing 7A |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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THSD7A |
Synonyms (NCBI Gene)
Gene synonyms aliases
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- |
Chromosome
Chromosome number
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7 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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7p21.3 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is found almost exclusively in endothelial cells from placenta and umbilical cord. The encoded protein appears to interact with alpha(V)beta(3) integrin and paxillin to inhibit endothelial cell migration and tube formation |
Causal |
Disease term |
Disease name |
dbSNP ID |
References |
Coronary artery disease |
Coronary Artery Disease |
rs137852988, rs121918313, rs121918529, rs121918531, rs137852340, rs1555800701, rs1215189537 |
29472232 |
Glaucoma |
Glaucoma, Glaucoma, Open-Angle |
rs121918355, rs1566660365, rs1566635134, rs121918356, rs1566634475, rs28936700, rs55771538, rs28936701, rs104893622, rs55989760, rs72549387, rs104893628, rs2125316417, rs104893629, rs74315328, rs121909193, rs74315330, rs74315329, rs74315332, rs74315334, rs74315336, rs74315338, rs74315341, rs121909194, rs74315331, rs1558603396, rs387907175, rs587778873, rs587778875, rs104894979, rs137854895, rs766425037, rs72549380, rs148542782, rs541217363, rs753021890, rs771076928, rs56010818, rs777678299, rs1446110883, rs1573274915, rs1587545234, rs751768343, rs944452644 View all (29 more) |
30054594, 29891935 |
Leukemia |
Leukemia, Myelocytic, Acute |
rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297 |
27903959 |
|
Unknown |
Disease term |
Disease name |
Evidence |
References |
Source |
Tourette Syndrome |
Tourette Syndrome |
|
|
GWAS |
Anorexia |
Anorexia |
|
|
GWAS |
Neuroticism |
Neuroticism |
|
|
GWAS |
Bipolar Disorder |
Bipolar Disorder |
|
|
GWAS |
Metabolic Syndrome |
Metabolic Syndrome |
|
|
GWAS |
Crohn Disease |
Crohn Disease |
|
|
GWAS |
Ovarian cancer |
Ovarian cancer |
Conditional KD of IL6 in the OCCA xenograft model delays tumor growth |
|
GWAS, CBGDA |
Mental Depression |
Mental Depression |
|
|
GWAS |
Insomnia |
Insomnia |
|
|
GWAS |
Glioblastoma |
Glioblastoma |
CRISPR screening of E3 ubiquitin ligases reveals Ring Finger Protein 185 as a novel tumor suppressor in glioblastoma repressed by promoter hypermethylation and miR-587 |
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GWAS, CBGDA |
Polymyositis |
Polymyositis |
|
|
GWAS |
|
Associations from Text Mining |
Disease Name |
Relationship Type |
References |
Autoimmune Diseases |
Associate
|
30520531 |
Bipolar Disorder |
Associate
|
32627186, 40562893 |
Breast Neoplasms |
Stimulate
|
31443644 |
Carcinoma Ovarian Epithelial |
Associate
|
30898391 |
Carcinoma Squamous Cell |
Associate
|
37445817 |
Colorectal Neoplasms |
Stimulate
|
31443644 |
Colorectal Neoplasms |
Associate
|
40098080 |
Drug Hypersensitivity |
Associate
|
30868298 |
Endometrial Neoplasms |
Associate
|
27436855 |
Eosinophilia |
Associate
|
31705303 |
Esophageal Squamous Cell Carcinoma |
Associate
|
35755171 |
Glioblastoma |
Associate
|
32253832 |
Glomerulonephritis Membranous |
Associate
|
25394321, 26393352, 27436855, 28801527, 30032157, 30520531, 30619370, 30868298, 31443644, 31705303, 32879127, 33849930, 36277605 |
Inflammation |
Associate
|
37905960 |
Kidney Diseases |
Associate
|
31443644 |
Kimura Disease |
Associate
|
30868298 |
Lymphatic Metastasis |
Associate
|
31443644 |
Mental Disorders |
Associate
|
32627186 |
Neoplasm Metastasis |
Associate
|
27436855 |
Neoplasms |
Associate
|
27436855, 28801527, 31443644, 37445817, 37905960, 40098080 |
Neoplasms |
Stimulate
|
30619370 |
Osteoporosis |
Associate
|
22957024 |
Proteinuria |
Associate
|
28801527, 30868298, 31443644 |
Schizophrenia |
Associate
|
19521112 |
Sick Sinus Syndrome |
Associate
|
27436855 |
Stomach Neoplasms |
Stimulate
|
37905960 |
Thrombosis |
Associate
|
23742623 |
Venous Thromboembolism |
Associate
|
23742623 |
|