PI16 (peptidase inhibitor 16)

Gene
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
221476
Gene name Gene Name - the full gene name approved by the HGNC.
Peptidase inhibitor 16
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
PI16
Synonyms (NCBI Gene) Gene synonyms aliases
CD364, CRISP9, MSMBBP, PSPBP
Chromosome Chromosome number
6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
6p21.2
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(8)
miRTarBase ID miRNA Experiments Reference
MIRT023574 hsa-miR-1-3p Microarray 18668037
MIRT1232688 hsa-miR-1193 CLIP-seq
MIRT1232689 hsa-miR-1827 CLIP-seq
MIRT1232690 hsa-miR-3064-3p CLIP-seq
MIRT1232691 hsa-miR-3650 CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(5)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32296183
GO:0005615 Component Extracellular space IBA 21873635
GO:0010466 Process Negative regulation of peptidase activity IEA
GO:0030414 Function Peptidase inhibitor activity IEA
GO:0061052 Process Negative regulation of cell growth involved in cardiac muscle cell development IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Q6UXB8
Protein name Peptidase inhibitor 16 (PI-16) (Cysteine-rich secretory protein 9) (CRISP-9) (PSP94-binding protein) (CD antigen CD364)
Protein function May inhibit cardiomyocyte growth.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00188 CAP 37 → 165 Cysteine-rich secretory protein family Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in prostate, testis, ovary and intestine. Concentrates in prostate cancer patient's sera. {ECO:0000269|PubMed:15344909, ECO:0000269|PubMed:17062675}.
Sequence 
MHGSCSFLMLLLPLLLLLVATTGPVGALTDEEKRLMVELHNLYRAQVSPTASDMLHMRWD
EELAAFAKAYARQCVWGHNKERGRRGENLFAITDEGMDVPLAMEEWHHEREHYNLSAATC
SPGQMCGHYTQVVWAKTERIGCGSHFCEKLQGVEETNIELLVCNYEPPGNVKGKRPYQEG
TPCSQCPSGYHCKNSLCEPIGSPEDAQDLPYLVTEAPSFRATEASDSRKMGTPSSLATGI
PAFLVTEVSGSLATKALPAVETQAPTSLATKDPPSMATEAPPCVTTEVPSILAAHSLPSL
DEEPVTFPKSTHVPIPKSADKVTDKTKVPSRSPENSLDPKMSLTGARELLPHAQEEAEAE
AELPPSSEVLASVFPAQDKPGELQATLDHTGHTSSKSLPNFPNTSATANATGGRALALQS
SLPGAEGPDKPSVVSGLNSGPGHVWGPLLGLLLLPPLVLAGIF
Sequence length 463
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide Causal Diseases (1)
Causal
Disease term Disease name dbSNP ID References
Leukemia Leukemia, Myelocytic, Acute rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297 27903959
Show/Hide Unknown Diseases (1)
Unknown
Disease term Disease name Evidence References Source
Diabetes Diabetes GWAS
Show/Hide Text Mining Associations (12)
Associations from Text Mining
Disease Name Relationship Type References
Dementia Associate 34341761
Diabetes Mellitus Type 1 Associate 31127857
Hernia Stimulate 34341761
Inflammation Associate 27996045
Internal Hernia Associate 34341761
Irritable Bowel Syndrome Associate 35502856
Neoplasm Metastasis Inhibit 37525118
Neoplasms Inhibit 37525118
Prostatic Neoplasms Associate 19644707
Stomach Neoplasms Associate 39524442