Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
221079
Gene name Gene Name - the full gene name approved by the HGNC.
ARF like GTPase 5B
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ARL5B
Synonyms (NCBI Gene) Gene synonyms aliases
ARL8
Chromosome Chromosome number
10
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
10p12.31
Summary Summary of gene provided in NCBI Entrez Gene.
ARL5B (ARL8) belongs to a family of proteins that are structurally similar to ADP-ribosylation factors (ARFs; see MIM 103180). ARLs and ARFs are part of the RAS superfamily of regulatory GTPases.[supplied by OMIM, Nov 2010]
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT001567 hsa-miR-155-5p pSILAC 18668040
MIRT017382 hsa-miR-335-5p Microarray 18185580
MIRT001567 hsa-miR-155-5p Proteomics;Other 18668040
MIRT044984 hsa-miR-186-5p CLASH 23622248
MIRT669480 hsa-miR-6828-3p HITS-CLIP 23824327
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 32296183
GO:0005525 Function GTP binding IBA 21873635
GO:0005737 Component Cytoplasm IBA 21873635
GO:0005802 Component Trans-Golgi network IBA 21873635
GO:0006886 Process Intracellular protein transport IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
608909 23052 ENSG00000165997
Protein
UniProt ID Q96KC2
Protein name ADP-ribosylation factor-like protein 5B (ADP-ribosylation factor-like protein 8)
Protein function Binds and exchanges GTP and GDP.
PDB 1YZG
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00025 Arf 1 176 ADP-ribosylation factor family Domain
Sequence
Sequence length 179
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Melanoma melanoma rs121913315, rs121913323, rs137853080, rs137853081, rs121909232, rs121913388, rs104894094, rs104894095, rs104894097, rs104894098, rs104894099, rs104894109, rs137854599, rs11547328, rs104894340
View all (64 more)
22535842
Unknown
Disease term Disease name Evidence References Source
Mental depression Major Depressive Disorder 31164008 ClinVar
Associations from Text Mining
Disease Name Relationship Type References
Alzheimer Disease Associate 20932310
Breast Neoplasms Associate 32805088
Ovarian Neoplasms Associate 33419459
Precancerous Conditions Associate 32805088