Gene Gene information from NCBI Gene database.
Entrez ID 220992
Gene name Zinc finger protein 485
Gene symbol ZNF485
Synonyms (NCBI Gene)
-
Chromosome 10
Chromosome location 10q11.21
miRNA miRNA information provided by mirtarbase database.
428
miRTarBase ID miRNA Experiments Reference
MIRT043989 hsa-miR-378a-5p CLASH 23622248
MIRT043989 hsa-miR-378a-5p CLASH 23622248
MIRT541968 hsa-miR-374c-3p HITS-CLIP 21572407
MIRT528975 hsa-miR-6514-5p HITS-CLIP 21572407
MIRT499322 hsa-miR-4781-3p HITS-CLIP 21572407
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
15
GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IEA
GO:0000978 Function RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
GO:0001227 Function DNA-binding transcription repressor activity, RNA polymerase II-specific IEA
GO:0001228 Function DNA-binding transcription activator activity, RNA polymerase II-specific IBA
GO:0003677 Function DNA binding IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8NCK3
Protein name Zinc finger protein 485
Protein function May be involved in transcriptional regulation.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01352 KRAB 10 51 KRAB box Family
PF00096 zf-C2H2 130 152 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 158 180 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 242 264 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 270 292 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 298 320 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 326 348 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 354 376 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 382 404 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 410 432 Zinc finger, C2H2 type Domain
Sequence
MAPRAQIQGPLTFGDVAVAFTRIEWRHLDAAQRALYRDVMLENYGNLVSVGLLSSKPKLI
TQLEQGAEPWTEVREAPSGTHAVEDYWFETKMSALKQSTSEASVLGERTKSVMMEKGLDW
EGRSSTEKNYKCKECGKVFKYNSSFISHQRNHTSEKPHKCKECGIAFMNSSSLLNHHKVH
AGKQPYRCIECGKFLKKHSTFINHQRIHSREKPHKCIECGKTFRKNSILLSHQRIHTGQK
PYKCNDCGKAFAQNAALTRHERIHSGEKPFKCNKCGRAFRDNSTVLEHQKIHTGEKPYQC
NECGKAFRKSSTLISHQRMH
TGEKPYHCSKCGKSFRYSSSFAGHQKTHSGNKPYQCRDCG
KAFTKSSTLTGHQRIH
TGEKPYHCKKCGKAFRHSSGLVEHQRLHTGEKPYKCNECGKAFP
RSSALKQHKKIH
NKERAMKCS
Sequence length 441
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Generic Transcription Pathway
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
OLIGODENDROGLIOMA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations