Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID	220134
Gene name	Spindle and kinetochore associated complex subunit 1
Gene symbol	SKA1
Synonyms (NCBI Gene)	C18orf24
Chromosome	18
Chromosome location	18q21.1

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miRTarBase ID	miRNA	Experiments	Reference
MIRT016380	hsa-miR-193b-3p	Microarray	20304954
MIRT024386	hsa-miR-215-5p	Microarray	19074876
MIRT026316	hsa-miR-192-5p	Microarray	19074876
MIRT043769	hsa-miR-328-3p	CLASH	23622248
MIRT711382	hsa-miR-6771-3p	HITS-CLIP	19536157
MIRT711381	hsa-miR-3613-3p	HITS-CLIP	19536157
MIRT711380	hsa-miR-519d-5p	HITS-CLIP	19536157
MIRT711379	hsa-miR-5695	HITS-CLIP	19536157
MIRT711378	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT711377	hsa-miR-196a-3p	HITS-CLIP	19536157
MIRT711376	hsa-miR-515-5p	HITS-CLIP	19536157
MIRT711375	hsa-miR-519e-5p	HITS-CLIP	19536157
MIRT736834	hsa-miR-10a-5p	Luciferase reporter assayWestern blottingqRT-PCR	34002462
MIRT711382	hsa-miR-6771-3p	HITS-CLIP	19536157
MIRT711381	hsa-miR-3613-3p	HITS-CLIP	19536157
MIRT711380	hsa-miR-519d-5p	HITS-CLIP	19536157
MIRT711379	hsa-miR-5695	HITS-CLIP	19536157
MIRT711378	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT711377	hsa-miR-196a-3p	HITS-CLIP	19536157
MIRT711376	hsa-miR-515-5p	HITS-CLIP	19536157
MIRT711375	hsa-miR-519e-5p	HITS-CLIP	19536157
MIRT1350620	hsa-miR-1207-5p	CLIP-seq
MIRT1350621	hsa-miR-1268	CLIP-seq
MIRT1350622	hsa-miR-1268b	CLIP-seq
MIRT1350623	hsa-miR-1304	CLIP-seq
MIRT1350624	hsa-miR-1827	CLIP-seq
MIRT1350625	hsa-miR-2114	CLIP-seq
MIRT1350626	hsa-miR-2392	CLIP-seq
MIRT1350627	hsa-miR-24	CLIP-seq
MIRT1350628	hsa-miR-2467-5p	CLIP-seq
MIRT1350629	hsa-miR-3122	CLIP-seq
MIRT1350630	hsa-miR-3150b-3p	CLIP-seq
MIRT1350631	hsa-miR-3165	CLIP-seq
MIRT1350632	hsa-miR-3178	CLIP-seq
MIRT1350633	hsa-miR-3188	CLIP-seq
MIRT1350634	hsa-miR-3192	CLIP-seq
MIRT1350635	hsa-miR-330-3p	CLIP-seq
MIRT1350636	hsa-miR-3605-5p	CLIP-seq
MIRT1350637	hsa-miR-3614-5p	CLIP-seq
MIRT1350638	hsa-miR-3664-3p	CLIP-seq
MIRT1350639	hsa-miR-3665	CLIP-seq
MIRT1350640	hsa-miR-3675-3p	CLIP-seq
MIRT1350641	hsa-miR-3689a-3p	CLIP-seq
MIRT1350642	hsa-miR-3689c	CLIP-seq
MIRT1350643	hsa-miR-371-5p	CLIP-seq
MIRT1350644	hsa-miR-371b-5p	CLIP-seq
MIRT1350645	hsa-miR-382	CLIP-seq
MIRT1350646	hsa-miR-3913-5p	CLIP-seq
MIRT1350647	hsa-miR-3929	CLIP-seq
MIRT1350648	hsa-miR-3975	CLIP-seq
MIRT1350649	hsa-miR-410	CLIP-seq
MIRT1350650	hsa-miR-4261	CLIP-seq
MIRT1350651	hsa-miR-4284	CLIP-seq
MIRT1350652	hsa-miR-4419b	CLIP-seq
MIRT1350653	hsa-miR-4421	CLIP-seq
MIRT1350654	hsa-miR-4433	CLIP-seq
MIRT1350655	hsa-miR-4459	CLIP-seq
MIRT1350656	hsa-miR-4478	CLIP-seq
MIRT1350657	hsa-miR-4486	CLIP-seq
MIRT1350658	hsa-miR-4496	CLIP-seq
MIRT1350659	hsa-miR-451b	CLIP-seq
MIRT1350660	hsa-miR-4649-3p	CLIP-seq
MIRT1350661	hsa-miR-4683	CLIP-seq
MIRT1350662	hsa-miR-4684-5p	CLIP-seq
MIRT1350663	hsa-miR-4689	CLIP-seq
MIRT1350664	hsa-miR-4695-5p	CLIP-seq
MIRT1350665	hsa-miR-4715-5p	CLIP-seq
MIRT1350666	hsa-miR-4716-5p	CLIP-seq
MIRT1350667	hsa-miR-4722-5p	CLIP-seq
MIRT1350668	hsa-miR-4728-5p	CLIP-seq
MIRT1350669	hsa-miR-4736	CLIP-seq
MIRT1350670	hsa-miR-4743	CLIP-seq
MIRT1350671	hsa-miR-4763-3p	CLIP-seq
MIRT1350672	hsa-miR-4768-3p	CLIP-seq
MIRT1350673	hsa-miR-4779	CLIP-seq
MIRT1350674	hsa-miR-4784	CLIP-seq
MIRT1350675	hsa-miR-4786-5p	CLIP-seq
MIRT1350676	hsa-miR-485-5p	CLIP-seq
MIRT1350677	hsa-miR-498	CLIP-seq
MIRT1350678	hsa-miR-510	CLIP-seq
MIRT1350679	hsa-miR-512-5p	CLIP-seq
MIRT1350680	hsa-miR-541	CLIP-seq
MIRT1350681	hsa-miR-548c-3p	CLIP-seq
MIRT1350682	hsa-miR-548n	CLIP-seq
MIRT1350683	hsa-miR-548t	CLIP-seq
MIRT1350684	hsa-miR-550a	CLIP-seq
MIRT1350685	hsa-miR-585	CLIP-seq
MIRT1350686	hsa-miR-654-5p	CLIP-seq
MIRT1350687	hsa-miR-661	CLIP-seq
MIRT1350688	hsa-miR-764	CLIP-seq
MIRT1350689	hsa-miR-940	CLIP-seq
MIRT1350624	hsa-miR-1827	CLIP-seq
MIRT1350626	hsa-miR-2392	CLIP-seq
MIRT1350627	hsa-miR-24	CLIP-seq
MIRT1350629	hsa-miR-3122	CLIP-seq
MIRT1350632	hsa-miR-3178	CLIP-seq
MIRT1350634	hsa-miR-3192	CLIP-seq
MIRT1350636	hsa-miR-3605-5p	CLIP-seq
MIRT1350690	hsa-miR-3612	CLIP-seq
MIRT1350637	hsa-miR-3614-5p	CLIP-seq
MIRT1350641	hsa-miR-3689a-3p	CLIP-seq
MIRT1350642	hsa-miR-3689c	CLIP-seq
MIRT1350645	hsa-miR-382	CLIP-seq
MIRT1350646	hsa-miR-3913-5p	CLIP-seq
MIRT1350651	hsa-miR-4284	CLIP-seq
MIRT1350654	hsa-miR-4433	CLIP-seq
MIRT1350655	hsa-miR-4459	CLIP-seq
MIRT1350661	hsa-miR-4683	CLIP-seq
MIRT1350665	hsa-miR-4715-5p	CLIP-seq
MIRT1350667	hsa-miR-4722-5p	CLIP-seq
MIRT1350668	hsa-miR-4728-5p	CLIP-seq
MIRT1350670	hsa-miR-4743	CLIP-seq
MIRT1350672	hsa-miR-4768-3p	CLIP-seq
MIRT1350691	hsa-miR-490-3p	CLIP-seq
MIRT1350680	hsa-miR-541	CLIP-seq
MIRT1350692	hsa-miR-650	CLIP-seq
MIRT1350686	hsa-miR-654-5p	CLIP-seq
MIRT1350687	hsa-miR-661	CLIP-seq
MIRT1350689	hsa-miR-940	CLIP-seq
MIRT1350620	hsa-miR-1207-5p	CLIP-seq
MIRT1350621	hsa-miR-1268	CLIP-seq
MIRT1350622	hsa-miR-1268b	CLIP-seq
MIRT1350623	hsa-miR-1304	CLIP-seq
MIRT1350625	hsa-miR-2114	CLIP-seq
MIRT1350628	hsa-miR-2467-5p	CLIP-seq
MIRT1350633	hsa-miR-3188	CLIP-seq
MIRT1350634	hsa-miR-3192	CLIP-seq
MIRT1350637	hsa-miR-3614-5p	CLIP-seq
MIRT1350639	hsa-miR-3665	CLIP-seq
MIRT1350641	hsa-miR-3689a-3p	CLIP-seq
MIRT1350642	hsa-miR-3689c	CLIP-seq
MIRT1350648	hsa-miR-3975	CLIP-seq
MIRT1350654	hsa-miR-4433	CLIP-seq
MIRT1350655	hsa-miR-4459	CLIP-seq
MIRT1350657	hsa-miR-4486	CLIP-seq
MIRT2103894	hsa-miR-4656	CLIP-seq
MIRT1350661	hsa-miR-4683	CLIP-seq
MIRT1350668	hsa-miR-4728-5p	CLIP-seq
MIRT1350669	hsa-miR-4736	CLIP-seq
MIRT1350671	hsa-miR-4763-3p	CLIP-seq
MIRT1350672	hsa-miR-4768-3p	CLIP-seq
MIRT1350675	hsa-miR-4786-5p	CLIP-seq
MIRT2103895	hsa-miR-4793-5p	CLIP-seq
MIRT2103896	hsa-miR-4794	CLIP-seq
MIRT1350676	hsa-miR-485-5p	CLIP-seq
MIRT1350680	hsa-miR-541	CLIP-seq
MIRT1350684	hsa-miR-550a	CLIP-seq
MIRT1350685	hsa-miR-585	CLIP-seq
MIRT1350686	hsa-miR-654-5p	CLIP-seq
MIRT1350687	hsa-miR-661	CLIP-seq
MIRT1350688	hsa-miR-764	CLIP-seq
MIRT2103897	hsa-miR-4445	CLIP-seq
MIRT2103898	hsa-miR-4537	CLIP-seq
MIRT2328063	hsa-miR-624	CLIP-seq
MIRT2328064	hsa-miR-122	CLIP-seq
MIRT1350623	hsa-miR-1304	CLIP-seq
MIRT1350624	hsa-miR-1827	CLIP-seq
MIRT1350625	hsa-miR-2114	CLIP-seq
MIRT1350626	hsa-miR-2392	CLIP-seq
MIRT1350628	hsa-miR-2467-5p	CLIP-seq
MIRT1350629	hsa-miR-3122	CLIP-seq
MIRT1350630	hsa-miR-3150b-3p	CLIP-seq
MIRT1350631	hsa-miR-3165	CLIP-seq
MIRT1350633	hsa-miR-3188	CLIP-seq
MIRT1350634	hsa-miR-3192	CLIP-seq
MIRT2328065	hsa-miR-323b-3p	CLIP-seq
MIRT1350636	hsa-miR-3605-5p	CLIP-seq
MIRT1350637	hsa-miR-3614-5p	CLIP-seq
MIRT1350638	hsa-miR-3664-3p	CLIP-seq
MIRT1350641	hsa-miR-3689a-3p	CLIP-seq
MIRT1350642	hsa-miR-3689c	CLIP-seq
MIRT1350646	hsa-miR-3913-5p	CLIP-seq
MIRT1350647	hsa-miR-3929	CLIP-seq
MIRT1350648	hsa-miR-3975	CLIP-seq
MIRT1350651	hsa-miR-4284	CLIP-seq
MIRT1350652	hsa-miR-4419b	CLIP-seq
MIRT2328066	hsa-miR-4423-5p	CLIP-seq
MIRT1350654	hsa-miR-4433	CLIP-seq
MIRT1350655	hsa-miR-4459	CLIP-seq
MIRT2328067	hsa-miR-4463	CLIP-seq
MIRT1350656	hsa-miR-4478	CLIP-seq
MIRT2328068	hsa-miR-4494	CLIP-seq
MIRT1350660	hsa-miR-4649-3p	CLIP-seq
MIRT2103894	hsa-miR-4656	CLIP-seq
MIRT2328069	hsa-miR-4659a-3p	CLIP-seq
MIRT2328070	hsa-miR-4659b-3p	CLIP-seq
MIRT1350663	hsa-miR-4689	CLIP-seq
MIRT1350664	hsa-miR-4695-5p	CLIP-seq
MIRT1350666	hsa-miR-4716-5p	CLIP-seq
MIRT1350667	hsa-miR-4722-5p	CLIP-seq
MIRT1350668	hsa-miR-4728-5p	CLIP-seq
MIRT1350672	hsa-miR-4768-3p	CLIP-seq
MIRT1350673	hsa-miR-4779	CLIP-seq
MIRT1350674	hsa-miR-4784	CLIP-seq
MIRT2103895	hsa-miR-4793-5p	CLIP-seq
MIRT1350676	hsa-miR-485-5p	CLIP-seq
MIRT1350691	hsa-miR-490-3p	CLIP-seq
MIRT1350678	hsa-miR-510	CLIP-seq
MIRT1350679	hsa-miR-512-5p	CLIP-seq
MIRT2328071	hsa-miR-564	CLIP-seq
MIRT1350687	hsa-miR-661	CLIP-seq
MIRT1350689	hsa-miR-940	CLIP-seq
MIRT2328064	hsa-miR-122	CLIP-seq
MIRT2328066	hsa-miR-4423-5p	CLIP-seq
MIRT2328067	hsa-miR-4463	CLIP-seq
MIRT2328068	hsa-miR-4494	CLIP-seq
MIRT2328071	hsa-miR-564	CLIP-seq
MIRT1350620	hsa-miR-1207-5p	CLIP-seq
MIRT2328064	hsa-miR-122	CLIP-seq
MIRT2622921	hsa-miR-1234	CLIP-seq
MIRT2622922	hsa-miR-1262	CLIP-seq
MIRT1350621	hsa-miR-1268	CLIP-seq
MIRT1350622	hsa-miR-1268b	CLIP-seq
MIRT2622923	hsa-miR-1276	CLIP-seq
MIRT1350623	hsa-miR-1304	CLIP-seq
MIRT2622924	hsa-miR-1307	CLIP-seq
MIRT1350625	hsa-miR-2114	CLIP-seq
MIRT1350628	hsa-miR-2467-5p	CLIP-seq
MIRT1350629	hsa-miR-3122	CLIP-seq
MIRT2622925	hsa-miR-3135	CLIP-seq
MIRT1350630	hsa-miR-3150b-3p	CLIP-seq
MIRT1350631	hsa-miR-3165	CLIP-seq
MIRT1350633	hsa-miR-3188	CLIP-seq
MIRT1350634	hsa-miR-3192	CLIP-seq
MIRT1350635	hsa-miR-330-3p	CLIP-seq
MIRT1350637	hsa-miR-3614-5p	CLIP-seq
MIRT2622926	hsa-miR-3622b-5p	CLIP-seq
MIRT1350639	hsa-miR-3665	CLIP-seq
MIRT1350640	hsa-miR-3675-3p	CLIP-seq
MIRT1350641	hsa-miR-3689a-3p	CLIP-seq
MIRT1350642	hsa-miR-3689c	CLIP-seq
MIRT1350643	hsa-miR-371-5p	CLIP-seq
MIRT1350644	hsa-miR-371b-5p	CLIP-seq
MIRT1350646	hsa-miR-3913-5p	CLIP-seq
MIRT1350647	hsa-miR-3929	CLIP-seq
MIRT1350648	hsa-miR-3975	CLIP-seq
MIRT1350650	hsa-miR-4261	CLIP-seq
MIRT1350651	hsa-miR-4284	CLIP-seq
MIRT1350652	hsa-miR-4419b	CLIP-seq
MIRT1350653	hsa-miR-4421	CLIP-seq
MIRT2328066	hsa-miR-4423-5p	CLIP-seq
MIRT1350654	hsa-miR-4433	CLIP-seq
MIRT1350655	hsa-miR-4459	CLIP-seq
MIRT2328067	hsa-miR-4463	CLIP-seq
MIRT1350656	hsa-miR-4478	CLIP-seq
MIRT1350657	hsa-miR-4486	CLIP-seq
MIRT2328068	hsa-miR-4494	CLIP-seq
MIRT1350658	hsa-miR-4496	CLIP-seq
MIRT1350659	hsa-miR-451b	CLIP-seq
MIRT2622927	hsa-miR-4638-5p	CLIP-seq
MIRT2622928	hsa-miR-4645-5p	CLIP-seq
MIRT2622929	hsa-miR-4662a-5p	CLIP-seq
MIRT2622930	hsa-miR-4673	CLIP-seq
MIRT2622931	hsa-miR-4676-5p	CLIP-seq
MIRT1350661	hsa-miR-4683	CLIP-seq
MIRT1350662	hsa-miR-4684-5p	CLIP-seq
MIRT1350663	hsa-miR-4689	CLIP-seq
MIRT2622932	hsa-miR-4701-3p	CLIP-seq
MIRT1350668	hsa-miR-4728-5p	CLIP-seq
MIRT1350669	hsa-miR-4736	CLIP-seq
MIRT2622933	hsa-miR-4755-3p	CLIP-seq
MIRT1350671	hsa-miR-4763-3p	CLIP-seq
MIRT1350672	hsa-miR-4768-3p	CLIP-seq
MIRT2622934	hsa-miR-4772-3p	CLIP-seq
MIRT1350673	hsa-miR-4779	CLIP-seq
MIRT1350674	hsa-miR-4784	CLIP-seq
MIRT1350675	hsa-miR-4786-5p	CLIP-seq
MIRT2103895	hsa-miR-4793-5p	CLIP-seq
MIRT2103896	hsa-miR-4794	CLIP-seq
MIRT1350676	hsa-miR-485-5p	CLIP-seq
MIRT1350677	hsa-miR-498	CLIP-seq
MIRT1350680	hsa-miR-541	CLIP-seq
MIRT1350681	hsa-miR-548c-3p	CLIP-seq
MIRT1350684	hsa-miR-550a	CLIP-seq
MIRT2328071	hsa-miR-564	CLIP-seq
MIRT2622935	hsa-miR-575	CLIP-seq
MIRT1350685	hsa-miR-585	CLIP-seq
MIRT1350686	hsa-miR-654-5p	CLIP-seq
MIRT1350687	hsa-miR-661	CLIP-seq
MIRT1350688	hsa-miR-764	CLIP-seq
MIRT1350620	hsa-miR-1207-5p	CLIP-seq
MIRT2328064	hsa-miR-122	CLIP-seq
MIRT2622921	hsa-miR-1234	CLIP-seq
MIRT2622922	hsa-miR-1262	CLIP-seq
MIRT1350621	hsa-miR-1268	CLIP-seq
MIRT1350622	hsa-miR-1268b	CLIP-seq
MIRT2622923	hsa-miR-1276	CLIP-seq
MIRT1350623	hsa-miR-1304	CLIP-seq
MIRT2622924	hsa-miR-1307	CLIP-seq
MIRT1350625	hsa-miR-2114	CLIP-seq
MIRT1350628	hsa-miR-2467-5p	CLIP-seq
MIRT1350629	hsa-miR-3122	CLIP-seq
MIRT2622925	hsa-miR-3135	CLIP-seq
MIRT1350630	hsa-miR-3150b-3p	CLIP-seq
MIRT1350631	hsa-miR-3165	CLIP-seq
MIRT1350633	hsa-miR-3188	CLIP-seq
MIRT1350634	hsa-miR-3192	CLIP-seq
MIRT1350635	hsa-miR-330-3p	CLIP-seq
MIRT1350637	hsa-miR-3614-5p	CLIP-seq
MIRT1350639	hsa-miR-3665	CLIP-seq
MIRT1350640	hsa-miR-3675-3p	CLIP-seq
MIRT1350641	hsa-miR-3689a-3p	CLIP-seq
MIRT1350642	hsa-miR-3689c	CLIP-seq
MIRT1350643	hsa-miR-371-5p	CLIP-seq
MIRT1350644	hsa-miR-371b-5p	CLIP-seq
MIRT1350646	hsa-miR-3913-5p	CLIP-seq
MIRT1350647	hsa-miR-3929	CLIP-seq
MIRT1350648	hsa-miR-3975	CLIP-seq
MIRT1350652	hsa-miR-4419b	CLIP-seq
MIRT1350653	hsa-miR-4421	CLIP-seq
MIRT2328066	hsa-miR-4423-5p	CLIP-seq
MIRT1350654	hsa-miR-4433	CLIP-seq
MIRT1350655	hsa-miR-4459	CLIP-seq
MIRT2328067	hsa-miR-4463	CLIP-seq
MIRT1350656	hsa-miR-4478	CLIP-seq
MIRT1350657	hsa-miR-4486	CLIP-seq
MIRT2328068	hsa-miR-4494	CLIP-seq
MIRT1350659	hsa-miR-451b	CLIP-seq
MIRT2622927	hsa-miR-4638-5p	CLIP-seq
MIRT1350661	hsa-miR-4683	CLIP-seq
MIRT1350662	hsa-miR-4684-5p	CLIP-seq
MIRT1350663	hsa-miR-4689	CLIP-seq
MIRT2622932	hsa-miR-4701-3p	CLIP-seq
MIRT1350668	hsa-miR-4728-5p	CLIP-seq
MIRT1350669	hsa-miR-4736	CLIP-seq
MIRT1350671	hsa-miR-4763-3p	CLIP-seq
MIRT1350672	hsa-miR-4768-3p	CLIP-seq
MIRT1350673	hsa-miR-4779	CLIP-seq
MIRT1350674	hsa-miR-4784	CLIP-seq
MIRT1350675	hsa-miR-4786-5p	CLIP-seq
MIRT2103895	hsa-miR-4793-5p	CLIP-seq
MIRT2103896	hsa-miR-4794	CLIP-seq
MIRT1350676	hsa-miR-485-5p	CLIP-seq
MIRT1350677	hsa-miR-498	CLIP-seq
MIRT1350680	hsa-miR-541	CLIP-seq
MIRT1350681	hsa-miR-548c-3p	CLIP-seq
MIRT1350684	hsa-miR-550a	CLIP-seq
MIRT2328071	hsa-miR-564	CLIP-seq
MIRT1350685	hsa-miR-585	CLIP-seq
MIRT1350686	hsa-miR-654-5p	CLIP-seq
MIRT1350687	hsa-miR-661	CLIP-seq
MIRT1350688	hsa-miR-764	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0000070	Process	Mitotic sister chromatid segregation	IMP	17093495, 19289083
GO:0000278	Process	Mitotic cell cycle	IBA
GO:0000278	Process	Mitotic cell cycle	IMP	19289083
GO:0000280	Process	Nuclear division	IEA
GO:0000775	Component	Chromosome, centromeric region	IEA
GO:0000776	Component	Kinetochore	IDA	24413531
GO:0000776	Component	Kinetochore	IEA
GO:0000776	Component	Kinetochore	IPI	21633384
GO:0000940	Component	Outer kinetochore	IBA
GO:0000940	Component	Outer kinetochore	IDA	17093495, 19289083, 26981768, 28479321
GO:0005515	Function	Protein binding	IPI	16189514, 17093495, 19289083, 19360002, 25416956, 26496610, 28514442, 31515488, 32296183, 33961781, 36592928
GO:0005654	Component	Nucleoplasm	IDA
GO:0005694	Component	Chromosome	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IDA	26981768
GO:0005813	Component	Centrosome	IEA
GO:0005819	Component	Spindle	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005856	Component	Cytoskeleton	IEA
GO:0005874	Component	Microtubule	IEA
GO:0005876	Component	Spindle microtubule	IBA
GO:0005876	Component	Spindle microtubule	IDA	17093495, 19289083
GO:0005929	Component	Cilium	IDA
GO:0007056	Process	Spindle assembly involved in female meiosis	ISS
GO:0007059	Process	Chromosome segregation	IBA
GO:0007059	Process	Chromosome segregation	IEA
GO:0007080	Process	Mitotic metaphase chromosome alignment	IMP	28495837
GO:0008017	Function	Microtubule binding	IBA
GO:0008017	Function	Microtubule binding	IDA	19289083, 24413531, 29487209
GO:0008017	Function	Microtubule binding	IEA
GO:0015630	Component	Microtubule cytoskeleton	IDA
GO:0031110	Process	Regulation of microtubule polymerization or depolymerization	IBA
GO:0031110	Process	Regulation of microtubule polymerization or depolymerization	IDA	19289083
GO:0031116	Process	Positive regulation of microtubule polymerization	IDA	27225956
GO:0034451	Component	Centriolar satellite	IDA
GO:0036064	Component	Ciliary basal body	IDA
GO:0045171	Component	Intercellular bridge	IDA
GO:0051296	Process	Establishment of meiotic spindle orientation	ISS
GO:0051301	Process	Cell division	IEA
GO:0051310	Process	Metaphase chromosome alignment	IMP	22371557
GO:0051315	Process	Attachment of mitotic spindle microtubules to kinetochore	IDA	29487209
GO:0051315	Process	Attachment of mitotic spindle microtubules to kinetochore	IMP	36592928
GO:0051649	Process	Establishment of localization in cell	IEA
GO:0051656	Process	Establishment of organelle localization	IEA
GO:0072686	Component	Mitotic spindle	IBA
GO:0072686	Component	Mitotic spindle	IDA	26981768
GO:0098813	Process	Nuclear chromosome segregation	IEA
GO:0140499	Process	Negative regulation of mitotic spindle assembly checkpoint signaling	IMP	26981768
GO:0170027	Component	SKA complex	IDA	31804178
GO:1990498	Component	Mitotic spindle microtubule	IDA	27225956

MIM	HGNC	e!Ensembl
616673	28109	ENSG00000154839

Q96BD8

Protein name

SKA complex subunit 1 (Spindle and kinetochore-associated protein 1)

Protein function

Component of the SKA complex, a microtubule plus end-binding complex of the outer kinetochore that stabilizes spindle microtubule-kinetochore attachments, promotes alignment of chromosomes at the mitotic spindle equator (chromosome congression)

PDB

4AJ5 , 4C9Y , 4CA0

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF07160	SKA1	16 → 248	Spindle and kinetochore-associated protein 1	Family

Sequence

MASSDLEQLCSHVNEKIGNIKKTLSLRNCGQEPTLKTVLNKIGDEIIVINELLNKLELEI
QYQEQTNNSLKELCESLEEDYKDIEHLKENVPSHLPQVTVTQSCVKGSDLDPEEPIKVEE
PEPVKKPPKEQRSIKEMPFITCDEFNGVPSYMKSRLTYNQINDVIKEINKAVISKYKILH
QPKKSMNSVTRNLYHRFIDEETKDTKGRYFIVEADIKEFTTLKADKKFHVLLNILRHCRR
LSEVRGGGLTRYVIT

Sequence length

255

Interactions

View interactions

	Reactome
			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation

SKA1 (spindle and kinetochore associated complex subunit 1)