Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	2181
Gene name	Acyl-CoA synthetase long chain family member 3
Gene symbol	ACSL3
Synonyms (NCBI Gene)	ACS3FACL3LACS 3LACS3PRO2194
Chromosome	2
Chromosome location	2q36.1
Summary	The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty

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miRTarBase ID	miRNA	Experiments	Reference
MIRT017614	hsa-miR-335-5p	Microarray	18185580
MIRT019639	hsa-miR-340-5p	Sequencing	20371350
MIRT019874	hsa-miR-375	Microarray	20215506
MIRT024182	hsa-miR-221-3p	Sequencing	20371350
MIRT048455	hsa-miR-100-5p	CLASH	23622248
MIRT446308	hsa-miR-548ac	PAR-CLIP	22100165
MIRT446307	hsa-miR-548bb-3p	PAR-CLIP	22100165
MIRT446306	hsa-miR-548d-3p	PAR-CLIP	22100165
MIRT446305	hsa-miR-548h-3p	PAR-CLIP	22100165
MIRT446304	hsa-miR-548z	PAR-CLIP	22100165
MIRT446303	hsa-miR-548ae-3p	PAR-CLIP	22100165
MIRT446302	hsa-miR-548ah-3p	PAR-CLIP	22100165
MIRT446301	hsa-miR-548aj-3p	PAR-CLIP	22100165
MIRT446300	hsa-miR-548am-3p	PAR-CLIP	22100165
MIRT446299	hsa-miR-548aq-3p	PAR-CLIP	22100165
MIRT446298	hsa-miR-548j-3p	PAR-CLIP	22100165
MIRT446297	hsa-miR-548x-3p	PAR-CLIP	22100165
MIRT446296	hsa-miR-5582-3p	PAR-CLIP	22100165
MIRT446295	hsa-miR-551b-5p	PAR-CLIP	22100165
MIRT446294	hsa-miR-329-5p	PAR-CLIP	22100165
MIRT446293	hsa-miR-96-3p	PAR-CLIP	22100165
MIRT446292	hsa-miR-655-5p	PAR-CLIP	22100165
MIRT441287	hsa-miR-377-5p	PAR-CLIP	22100165
MIRT446291	hsa-miR-6086	PAR-CLIP	22100165
MIRT441287	hsa-miR-377-5p	HITS-CLIP	24374217
MIRT728396	hsa-miR-26a-5p	HITS-CLIP	22473208
MIRT728395	hsa-miR-26b-5p	HITS-CLIP	22473208
MIRT441287	hsa-miR-377-5p	HITS-CLIP	24374217
MIRT732422	hsa-miR-26a-1-3p	Luciferase reporter assayqRT-PCRWestern blot	25961460
MIRT732422	hsa-miR-26a-1-3p	Luciferase reporter assayqRT-PCRWestern blot	25961460
MIRT446308	hsa-miR-548ac	PAR-CLIP	22100165
MIRT446307	hsa-miR-548bb-3p	PAR-CLIP	22100165
MIRT446306	hsa-miR-548d-3p	PAR-CLIP	22100165
MIRT446305	hsa-miR-548h-3p	PAR-CLIP	22100165
MIRT446304	hsa-miR-548z	PAR-CLIP	22100165
MIRT446303	hsa-miR-548ae-3p	PAR-CLIP	22100165
MIRT446302	hsa-miR-548ah-3p	PAR-CLIP	22100165
MIRT446301	hsa-miR-548aj-3p	PAR-CLIP	22100165
MIRT446300	hsa-miR-548am-3p	PAR-CLIP	22100165
MIRT446299	hsa-miR-548aq-3p	PAR-CLIP	22100165
MIRT446298	hsa-miR-548j-3p	PAR-CLIP	22100165
MIRT446297	hsa-miR-548x-3p	PAR-CLIP	22100165
MIRT446296	hsa-miR-5582-3p	PAR-CLIP	22100165
MIRT446295	hsa-miR-551b-5p	PAR-CLIP	22100165
MIRT446294	hsa-miR-329-5p	PAR-CLIP	22100165
MIRT446293	hsa-miR-96-3p	PAR-CLIP	22100165
MIRT446292	hsa-miR-655-5p	PAR-CLIP	22100165
MIRT441287	hsa-miR-377-5p	PAR-CLIP	22100165
MIRT446291	hsa-miR-6086	PAR-CLIP	22100165
MIRT763481	hsa-miR-1183	CLIP-seq
MIRT763482	hsa-miR-1208	CLIP-seq
MIRT763483	hsa-miR-1245b-3p	CLIP-seq
MIRT763484	hsa-miR-129-5p	CLIP-seq
MIRT763485	hsa-miR-1297	CLIP-seq
MIRT763486	hsa-miR-1301	CLIP-seq
MIRT763487	hsa-miR-1305	CLIP-seq
MIRT763488	hsa-miR-141	CLIP-seq
MIRT763489	hsa-miR-200a	CLIP-seq
MIRT763490	hsa-miR-25	CLIP-seq
MIRT763491	hsa-miR-26a	CLIP-seq
MIRT763492	hsa-miR-26b	CLIP-seq
MIRT763493	hsa-miR-300	CLIP-seq
MIRT763494	hsa-miR-3065-5p	CLIP-seq
MIRT763495	hsa-miR-3120-3p	CLIP-seq
MIRT763496	hsa-miR-3137	CLIP-seq
MIRT763497	hsa-miR-3156-5p	CLIP-seq
MIRT763498	hsa-miR-32	CLIP-seq
MIRT763499	hsa-miR-3200-5p	CLIP-seq
MIRT763500	hsa-miR-337-3p	CLIP-seq
MIRT763501	hsa-miR-342-3p	CLIP-seq
MIRT763502	hsa-miR-345	CLIP-seq
MIRT763503	hsa-miR-363	CLIP-seq
MIRT763504	hsa-miR-3646	CLIP-seq
MIRT763505	hsa-miR-367	CLIP-seq
MIRT763506	hsa-miR-3670	CLIP-seq
MIRT763507	hsa-miR-3672	CLIP-seq
MIRT763508	hsa-miR-3685	CLIP-seq
MIRT763509	hsa-miR-377	CLIP-seq
MIRT763510	hsa-miR-381	CLIP-seq
MIRT763511	hsa-miR-384	CLIP-seq
MIRT763512	hsa-miR-3924	CLIP-seq
MIRT763513	hsa-miR-3941	CLIP-seq
MIRT763514	hsa-miR-421	CLIP-seq
MIRT763515	hsa-miR-4303	CLIP-seq
MIRT763516	hsa-miR-4457	CLIP-seq
MIRT763517	hsa-miR-4465	CLIP-seq
MIRT763518	hsa-miR-466	CLIP-seq
MIRT763519	hsa-miR-4660	CLIP-seq
MIRT763520	hsa-miR-4672	CLIP-seq
MIRT763521	hsa-miR-4695-3p	CLIP-seq
MIRT763522	hsa-miR-4709-3p	CLIP-seq
MIRT763523	hsa-miR-4709-5p	CLIP-seq
MIRT763524	hsa-miR-4742-3p	CLIP-seq
MIRT763525	hsa-miR-498	CLIP-seq
MIRT763526	hsa-miR-5047	CLIP-seq
MIRT763527	hsa-miR-513b	CLIP-seq
MIRT763528	hsa-miR-548p	CLIP-seq
MIRT763529	hsa-miR-586	CLIP-seq
MIRT763530	hsa-miR-92a	CLIP-seq
MIRT763531	hsa-miR-92b	CLIP-seq
MIRT1924995	hsa-miR-105	CLIP-seq
MIRT763481	hsa-miR-1183	CLIP-seq
MIRT763482	hsa-miR-1208	CLIP-seq
MIRT763485	hsa-miR-1297	CLIP-seq
MIRT1924996	hsa-miR-154	CLIP-seq
MIRT1924997	hsa-miR-181a	CLIP-seq
MIRT1924998	hsa-miR-181b	CLIP-seq
MIRT1924999	hsa-miR-181c	CLIP-seq
MIRT1925000	hsa-miR-181d	CLIP-seq
MIRT1925001	hsa-miR-1908	CLIP-seq
MIRT763491	hsa-miR-26a	CLIP-seq
MIRT763492	hsa-miR-26b	CLIP-seq
MIRT763493	hsa-miR-300	CLIP-seq
MIRT1925002	hsa-miR-3115	CLIP-seq
MIRT763496	hsa-miR-3137	CLIP-seq
MIRT1925003	hsa-miR-3152-5p	CLIP-seq
MIRT1925004	hsa-miR-3177-5p	CLIP-seq
MIRT763499	hsa-miR-3200-5p	CLIP-seq
MIRT763500	hsa-miR-337-3p	CLIP-seq
MIRT1925005	hsa-miR-3591-5p	CLIP-seq
MIRT763506	hsa-miR-3670	CLIP-seq
MIRT1925006	hsa-miR-3671	CLIP-seq
MIRT763508	hsa-miR-3685	CLIP-seq
MIRT1925007	hsa-miR-371-5p	CLIP-seq
MIRT1925008	hsa-miR-371b-5p	CLIP-seq
MIRT763510	hsa-miR-381	CLIP-seq
MIRT1925009	hsa-miR-382	CLIP-seq
MIRT763511	hsa-miR-384	CLIP-seq
MIRT763513	hsa-miR-3941	CLIP-seq
MIRT763514	hsa-miR-421	CLIP-seq
MIRT1925010	hsa-miR-4262	CLIP-seq
MIRT1925011	hsa-miR-4280	CLIP-seq
MIRT763515	hsa-miR-4303	CLIP-seq
MIRT763517	hsa-miR-4465	CLIP-seq
MIRT763518	hsa-miR-466	CLIP-seq
MIRT763520	hsa-miR-4672	CLIP-seq
MIRT1925012	hsa-miR-4731-3p	CLIP-seq
MIRT1925013	hsa-miR-4768-5p	CLIP-seq
MIRT1925014	hsa-miR-4774-3p	CLIP-seq
MIRT1925015	hsa-miR-4801	CLIP-seq
MIRT1925016	hsa-miR-4803	CLIP-seq
MIRT763525	hsa-miR-498	CLIP-seq
MIRT1925017	hsa-miR-520d-5p	CLIP-seq
MIRT1925018	hsa-miR-524-5p	CLIP-seq
MIRT1925019	hsa-miR-548a-5p	CLIP-seq
MIRT1925020	hsa-miR-548ab	CLIP-seq
MIRT1925021	hsa-miR-548ak	CLIP-seq
MIRT1925022	hsa-miR-548b-5p	CLIP-seq
MIRT1925023	hsa-miR-548c-5p	CLIP-seq
MIRT1925024	hsa-miR-548d-5p	CLIP-seq
MIRT1925025	hsa-miR-548h	CLIP-seq
MIRT1925026	hsa-miR-548i	CLIP-seq
MIRT1925027	hsa-miR-548j	CLIP-seq
MIRT1925028	hsa-miR-548k	CLIP-seq
MIRT1925029	hsa-miR-548l	CLIP-seq
MIRT763528	hsa-miR-548p	CLIP-seq
MIRT1925030	hsa-miR-548w	CLIP-seq
MIRT1925031	hsa-miR-548y	CLIP-seq
MIRT1925032	hsa-miR-559	CLIP-seq
MIRT1925033	hsa-miR-579	CLIP-seq
MIRT763529	hsa-miR-586	CLIP-seq
MIRT1925034	hsa-miR-663	CLIP-seq
MIRT763481	hsa-miR-1183	CLIP-seq
MIRT763482	hsa-miR-1208	CLIP-seq
MIRT763485	hsa-miR-1297	CLIP-seq
MIRT763486	hsa-miR-1301	CLIP-seq
MIRT763488	hsa-miR-141	CLIP-seq
MIRT1925001	hsa-miR-1908	CLIP-seq
MIRT763489	hsa-miR-200a	CLIP-seq
MIRT2166452	hsa-miR-2115	CLIP-seq
MIRT2166453	hsa-miR-223	CLIP-seq
MIRT2166454	hsa-miR-2355-5p	CLIP-seq
MIRT763490	hsa-miR-25	CLIP-seq
MIRT763491	hsa-miR-26a	CLIP-seq
MIRT763492	hsa-miR-26b	CLIP-seq
MIRT763494	hsa-miR-3065-5p	CLIP-seq
MIRT763495	hsa-miR-3120-3p	CLIP-seq
MIRT2166455	hsa-miR-3127-3p	CLIP-seq
MIRT763496	hsa-miR-3137	CLIP-seq
MIRT763498	hsa-miR-32	CLIP-seq
MIRT763499	hsa-miR-3200-5p	CLIP-seq
MIRT763500	hsa-miR-337-3p	CLIP-seq
MIRT2166456	hsa-miR-34a	CLIP-seq
MIRT2166457	hsa-miR-34b	CLIP-seq
MIRT2166458	hsa-miR-34c-5p	CLIP-seq
MIRT2166459	hsa-miR-3607-5p	CLIP-seq
MIRT2166460	hsa-miR-3613-3p	CLIP-seq
MIRT763503	hsa-miR-363	CLIP-seq
MIRT763504	hsa-miR-3646	CLIP-seq
MIRT2166461	hsa-miR-3662	CLIP-seq
MIRT763505	hsa-miR-367	CLIP-seq
MIRT763506	hsa-miR-3670	CLIP-seq
MIRT763507	hsa-miR-3672	CLIP-seq
MIRT2166462	hsa-miR-3682-5p	CLIP-seq
MIRT763508	hsa-miR-3685	CLIP-seq
MIRT1925009	hsa-miR-382	CLIP-seq
MIRT763511	hsa-miR-384	CLIP-seq
MIRT763513	hsa-miR-3941	CLIP-seq
MIRT2166463	hsa-miR-409-3p	CLIP-seq
MIRT763514	hsa-miR-421	CLIP-seq
MIRT763515	hsa-miR-4303	CLIP-seq
MIRT2166464	hsa-miR-4421	CLIP-seq
MIRT763517	hsa-miR-4465	CLIP-seq
MIRT2166465	hsa-miR-449a	CLIP-seq
MIRT2166466	hsa-miR-449b	CLIP-seq
MIRT2166467	hsa-miR-4517	CLIP-seq
MIRT2166468	hsa-miR-4659a-3p	CLIP-seq
MIRT2166469	hsa-miR-4659b-3p	CLIP-seq
MIRT763518	hsa-miR-466	CLIP-seq
MIRT763519	hsa-miR-4660	CLIP-seq
MIRT2166470	hsa-miR-4668-3p	CLIP-seq
MIRT2166471	hsa-miR-4668-5p	CLIP-seq
MIRT763520	hsa-miR-4672	CLIP-seq
MIRT2166472	hsa-miR-4697-3p	CLIP-seq
MIRT2166473	hsa-miR-4706	CLIP-seq
MIRT2166474	hsa-miR-4711-5p	CLIP-seq
MIRT1925012	hsa-miR-4731-3p	CLIP-seq
MIRT2166475	hsa-miR-4733-5p	CLIP-seq
MIRT763524	hsa-miR-4742-3p	CLIP-seq
MIRT2166476	hsa-miR-4749-5p	CLIP-seq
MIRT2166477	hsa-miR-4760-5p	CLIP-seq
MIRT2166478	hsa-miR-4762-5p	CLIP-seq
MIRT2166479	hsa-miR-4775	CLIP-seq
MIRT2166480	hsa-miR-4778-3p	CLIP-seq
MIRT1925015	hsa-miR-4801	CLIP-seq
MIRT763525	hsa-miR-498	CLIP-seq
MIRT2166481	hsa-miR-500a	CLIP-seq
MIRT763526	hsa-miR-5047	CLIP-seq
MIRT2166482	hsa-miR-514	CLIP-seq
MIRT2166483	hsa-miR-514b-3p	CLIP-seq
MIRT2166484	hsa-miR-516a-3p	CLIP-seq
MIRT2166485	hsa-miR-522	CLIP-seq
MIRT1925019	hsa-miR-548a-5p	CLIP-seq
MIRT1925020	hsa-miR-548ab	CLIP-seq
MIRT2166486	hsa-miR-548ae	CLIP-seq
MIRT2166487	hsa-miR-548aj	CLIP-seq
MIRT1925021	hsa-miR-548ak	CLIP-seq
MIRT2166488	hsa-miR-548am	CLIP-seq
MIRT1925022	hsa-miR-548b-5p	CLIP-seq
MIRT2166489	hsa-miR-548c-3p	CLIP-seq
MIRT1925023	hsa-miR-548c-5p	CLIP-seq
MIRT1925024	hsa-miR-548d-5p	CLIP-seq
MIRT1925025	hsa-miR-548h	CLIP-seq
MIRT1925026	hsa-miR-548i	CLIP-seq
MIRT1925027	hsa-miR-548j	CLIP-seq
MIRT1925028	hsa-miR-548k	CLIP-seq
MIRT1925029	hsa-miR-548l	CLIP-seq
MIRT763528	hsa-miR-548p	CLIP-seq
MIRT1925030	hsa-miR-548w	CLIP-seq
MIRT2166490	hsa-miR-548x	CLIP-seq
MIRT1925031	hsa-miR-548y	CLIP-seq
MIRT1925032	hsa-miR-559	CLIP-seq
MIRT2166491	hsa-miR-570	CLIP-seq
MIRT763529	hsa-miR-586	CLIP-seq
MIRT2166492	hsa-miR-590-3p	CLIP-seq
MIRT2166493	hsa-miR-598	CLIP-seq
MIRT2166494	hsa-miR-603	CLIP-seq
MIRT2166495	hsa-miR-626	CLIP-seq
MIRT1925034	hsa-miR-663	CLIP-seq
MIRT2166496	hsa-miR-758	CLIP-seq
MIRT763530	hsa-miR-92a	CLIP-seq
MIRT763531	hsa-miR-92b	CLIP-seq
MIRT2166497	hsa-miR-935	CLIP-seq
MIRT763520	hsa-miR-4672	CLIP-seq
MIRT2425910	hsa-miR-1284	CLIP-seq
MIRT763485	hsa-miR-1297	CLIP-seq
MIRT2425911	hsa-miR-188-5p	CLIP-seq
MIRT763491	hsa-miR-26a	CLIP-seq
MIRT763492	hsa-miR-26b	CLIP-seq
MIRT763500	hsa-miR-337-3p	CLIP-seq
MIRT763508	hsa-miR-3685	CLIP-seq
MIRT763511	hsa-miR-384	CLIP-seq
MIRT763517	hsa-miR-4465	CLIP-seq
MIRT763525	hsa-miR-498	CLIP-seq
MIRT1925017	hsa-miR-520d-5p	CLIP-seq
MIRT1925018	hsa-miR-524-5p	CLIP-seq
MIRT763529	hsa-miR-586	CLIP-seq
MIRT2425912	hsa-miR-642a	CLIP-seq
MIRT763494	hsa-miR-3065-5p	CLIP-seq
MIRT763513	hsa-miR-3941	CLIP-seq
MIRT763518	hsa-miR-466	CLIP-seq
MIRT763520	hsa-miR-4672	CLIP-seq
MIRT1925019	hsa-miR-548a-5p	CLIP-seq
MIRT1925020	hsa-miR-548ab	CLIP-seq
MIRT1925021	hsa-miR-548ak	CLIP-seq
MIRT1925022	hsa-miR-548b-5p	CLIP-seq
MIRT1925023	hsa-miR-548c-5p	CLIP-seq
MIRT1925024	hsa-miR-548d-5p	CLIP-seq
MIRT1925025	hsa-miR-548h	CLIP-seq
MIRT1925026	hsa-miR-548i	CLIP-seq
MIRT1925027	hsa-miR-548j	CLIP-seq
MIRT1925030	hsa-miR-548w	CLIP-seq
MIRT1925031	hsa-miR-548y	CLIP-seq
MIRT1925032	hsa-miR-559	CLIP-seq
MIRT2468916	hsa-miR-1253	CLIP-seq
MIRT763485	hsa-miR-1297	CLIP-seq
MIRT763486	hsa-miR-1301	CLIP-seq
MIRT2468917	hsa-miR-130a	CLIP-seq
MIRT2468918	hsa-miR-130b	CLIP-seq
MIRT2468919	hsa-miR-137	CLIP-seq
MIRT763488	hsa-miR-141	CLIP-seq
MIRT2468920	hsa-miR-148a	CLIP-seq
MIRT2468921	hsa-miR-148b	CLIP-seq
MIRT2468922	hsa-miR-152	CLIP-seq
MIRT1925001	hsa-miR-1908	CLIP-seq
MIRT2468923	hsa-miR-19a	CLIP-seq
MIRT2468924	hsa-miR-19b	CLIP-seq
MIRT763489	hsa-miR-200a	CLIP-seq
MIRT2166453	hsa-miR-223	CLIP-seq
MIRT763491	hsa-miR-26a	CLIP-seq
MIRT763492	hsa-miR-26b	CLIP-seq
MIRT2468925	hsa-miR-301a	CLIP-seq
MIRT2468926	hsa-miR-301b	CLIP-seq
MIRT763494	hsa-miR-3065-5p	CLIP-seq
MIRT1925002	hsa-miR-3115	CLIP-seq
MIRT2166455	hsa-miR-3127-3p	CLIP-seq
MIRT2468927	hsa-miR-3140-3p	CLIP-seq
MIRT2468928	hsa-miR-3148	CLIP-seq
MIRT1925003	hsa-miR-3152-5p	CLIP-seq
MIRT763497	hsa-miR-3156-5p	CLIP-seq
MIRT2468929	hsa-miR-3161	CLIP-seq
MIRT763500	hsa-miR-337-3p	CLIP-seq
MIRT763504	hsa-miR-3646	CLIP-seq
MIRT2468930	hsa-miR-3660	CLIP-seq
MIRT2166461	hsa-miR-3662	CLIP-seq
MIRT2468931	hsa-miR-3663-3p	CLIP-seq
MIRT2468932	hsa-miR-3666	CLIP-seq
MIRT763507	hsa-miR-3672	CLIP-seq
MIRT763508	hsa-miR-3685	CLIP-seq
MIRT763509	hsa-miR-377	CLIP-seq
MIRT1925009	hsa-miR-382	CLIP-seq
MIRT763511	hsa-miR-384	CLIP-seq
MIRT2468933	hsa-miR-3915	CLIP-seq
MIRT2468934	hsa-miR-3928	CLIP-seq
MIRT763513	hsa-miR-3941	CLIP-seq
MIRT2468935	hsa-miR-3973	CLIP-seq
MIRT2166463	hsa-miR-409-3p	CLIP-seq
MIRT2468936	hsa-miR-410	CLIP-seq
MIRT2468937	hsa-miR-4295	CLIP-seq
MIRT2468938	hsa-miR-4307	CLIP-seq
MIRT2468939	hsa-miR-4312	CLIP-seq
MIRT2166464	hsa-miR-4421	CLIP-seq
MIRT763516	hsa-miR-4457	CLIP-seq
MIRT763517	hsa-miR-4465	CLIP-seq
MIRT2468940	hsa-miR-4496	CLIP-seq
MIRT2166467	hsa-miR-4517	CLIP-seq
MIRT2468941	hsa-miR-4526	CLIP-seq
MIRT2468942	hsa-miR-454	CLIP-seq
MIRT2468943	hsa-miR-4653-3p	CLIP-seq
MIRT763518	hsa-miR-466	CLIP-seq
MIRT763519	hsa-miR-4660	CLIP-seq
MIRT2166471	hsa-miR-4668-5p	CLIP-seq
MIRT763520	hsa-miR-4672	CLIP-seq
MIRT763521	hsa-miR-4695-3p	CLIP-seq
MIRT2166472	hsa-miR-4697-3p	CLIP-seq
MIRT2166473	hsa-miR-4706	CLIP-seq
MIRT2166474	hsa-miR-4711-5p	CLIP-seq
MIRT1925012	hsa-miR-4731-3p	CLIP-seq
MIRT2468944	hsa-miR-4735-5p	CLIP-seq
MIRT2166476	hsa-miR-4749-5p	CLIP-seq
MIRT2166477	hsa-miR-4760-5p	CLIP-seq
MIRT1925014	hsa-miR-4774-3p	CLIP-seq
MIRT2166479	hsa-miR-4775	CLIP-seq
MIRT1925015	hsa-miR-4801	CLIP-seq
MIRT1925016	hsa-miR-4803	CLIP-seq
MIRT763525	hsa-miR-498	CLIP-seq
MIRT2166481	hsa-miR-500a	CLIP-seq
MIRT763526	hsa-miR-5047	CLIP-seq
MIRT763527	hsa-miR-513b	CLIP-seq
MIRT2166485	hsa-miR-522	CLIP-seq
MIRT1925019	hsa-miR-548a-5p	CLIP-seq
MIRT1925020	hsa-miR-548ab	CLIP-seq
MIRT1925021	hsa-miR-548ak	CLIP-seq
MIRT1925022	hsa-miR-548b-5p	CLIP-seq
MIRT2166489	hsa-miR-548c-3p	CLIP-seq
MIRT1925023	hsa-miR-548c-5p	CLIP-seq
MIRT1925024	hsa-miR-548d-5p	CLIP-seq
MIRT1925025	hsa-miR-548h	CLIP-seq
MIRT1925026	hsa-miR-548i	CLIP-seq
MIRT1925027	hsa-miR-548j	CLIP-seq
MIRT1925028	hsa-miR-548k	CLIP-seq
MIRT1925029	hsa-miR-548l	CLIP-seq
MIRT1925030	hsa-miR-548w	CLIP-seq
MIRT1925031	hsa-miR-548y	CLIP-seq
MIRT1925032	hsa-miR-559	CLIP-seq
MIRT2468945	hsa-miR-580	CLIP-seq
MIRT763529	hsa-miR-586	CLIP-seq
MIRT2166492	hsa-miR-590-3p	CLIP-seq
MIRT2166493	hsa-miR-598	CLIP-seq
MIRT2166495	hsa-miR-626	CLIP-seq
MIRT2468946	hsa-miR-633	CLIP-seq
MIRT1925034	hsa-miR-663	CLIP-seq
MIRT2468947	hsa-miR-889	CLIP-seq
MIRT2166497	hsa-miR-935	CLIP-seq
MIRT2468916	hsa-miR-1253	CLIP-seq
MIRT763485	hsa-miR-1297	CLIP-seq
MIRT763486	hsa-miR-1301	CLIP-seq
MIRT2468917	hsa-miR-130a	CLIP-seq
MIRT2468918	hsa-miR-130b	CLIP-seq
MIRT2468919	hsa-miR-137	CLIP-seq
MIRT2468920	hsa-miR-148a	CLIP-seq
MIRT2468921	hsa-miR-148b	CLIP-seq
MIRT2468922	hsa-miR-152	CLIP-seq
MIRT1925001	hsa-miR-1908	CLIP-seq
MIRT2468923	hsa-miR-19a	CLIP-seq
MIRT2468924	hsa-miR-19b	CLIP-seq
MIRT2166453	hsa-miR-223	CLIP-seq
MIRT763491	hsa-miR-26a	CLIP-seq
MIRT763492	hsa-miR-26b	CLIP-seq
MIRT2468925	hsa-miR-301a	CLIP-seq
MIRT2468926	hsa-miR-301b	CLIP-seq
MIRT763494	hsa-miR-3065-5p	CLIP-seq
MIRT2468927	hsa-miR-3140-3p	CLIP-seq
MIRT2468928	hsa-miR-3148	CLIP-seq
MIRT1925003	hsa-miR-3152-5p	CLIP-seq
MIRT2468929	hsa-miR-3161	CLIP-seq
MIRT763499	hsa-miR-3200-5p	CLIP-seq
MIRT763500	hsa-miR-337-3p	CLIP-seq
MIRT763504	hsa-miR-3646	CLIP-seq
MIRT2468930	hsa-miR-3660	CLIP-seq
MIRT2166461	hsa-miR-3662	CLIP-seq
MIRT2468931	hsa-miR-3663-3p	CLIP-seq
MIRT2468932	hsa-miR-3666	CLIP-seq
MIRT763506	hsa-miR-3670	CLIP-seq
MIRT763507	hsa-miR-3672	CLIP-seq
MIRT763508	hsa-miR-3685	CLIP-seq
MIRT763509	hsa-miR-377	CLIP-seq
MIRT1925009	hsa-miR-382	CLIP-seq
MIRT763511	hsa-miR-384	CLIP-seq
MIRT2468933	hsa-miR-3915	CLIP-seq
MIRT2468934	hsa-miR-3928	CLIP-seq
MIRT2468935	hsa-miR-3973	CLIP-seq
MIRT2166463	hsa-miR-409-3p	CLIP-seq
MIRT2468936	hsa-miR-410	CLIP-seq
MIRT2468937	hsa-miR-4295	CLIP-seq
MIRT763515	hsa-miR-4303	CLIP-seq
MIRT2468938	hsa-miR-4307	CLIP-seq
MIRT2468939	hsa-miR-4312	CLIP-seq
MIRT2166464	hsa-miR-4421	CLIP-seq
MIRT763517	hsa-miR-4465	CLIP-seq
MIRT2468940	hsa-miR-4496	CLIP-seq
MIRT2166467	hsa-miR-4517	CLIP-seq
MIRT2468941	hsa-miR-4526	CLIP-seq
MIRT2468942	hsa-miR-454	CLIP-seq
MIRT2468943	hsa-miR-4653-3p	CLIP-seq
MIRT763519	hsa-miR-4660	CLIP-seq
MIRT2166471	hsa-miR-4668-5p	CLIP-seq
MIRT2166472	hsa-miR-4697-3p	CLIP-seq
MIRT2166473	hsa-miR-4706	CLIP-seq
MIRT2166474	hsa-miR-4711-5p	CLIP-seq
MIRT1925012	hsa-miR-4731-3p	CLIP-seq
MIRT2468944	hsa-miR-4735-5p	CLIP-seq
MIRT2166476	hsa-miR-4749-5p	CLIP-seq
MIRT1925014	hsa-miR-4774-3p	CLIP-seq
MIRT2166479	hsa-miR-4775	CLIP-seq
MIRT1925015	hsa-miR-4801	CLIP-seq
MIRT763525	hsa-miR-498	CLIP-seq
MIRT2166481	hsa-miR-500a	CLIP-seq
MIRT763526	hsa-miR-5047	CLIP-seq
MIRT2166485	hsa-miR-522	CLIP-seq
MIRT1925019	hsa-miR-548a-5p	CLIP-seq
MIRT1925020	hsa-miR-548ab	CLIP-seq
MIRT1925021	hsa-miR-548ak	CLIP-seq
MIRT1925022	hsa-miR-548b-5p	CLIP-seq
MIRT2166489	hsa-miR-548c-3p	CLIP-seq
MIRT1925023	hsa-miR-548c-5p	CLIP-seq
MIRT1925024	hsa-miR-548d-5p	CLIP-seq
MIRT1925025	hsa-miR-548h	CLIP-seq
MIRT1925026	hsa-miR-548i	CLIP-seq
MIRT1925027	hsa-miR-548j	CLIP-seq
MIRT1925028	hsa-miR-548k	CLIP-seq
MIRT1925029	hsa-miR-548l	CLIP-seq
MIRT1925030	hsa-miR-548w	CLIP-seq
MIRT1925031	hsa-miR-548y	CLIP-seq
MIRT1925032	hsa-miR-559	CLIP-seq
MIRT2468945	hsa-miR-580	CLIP-seq
MIRT763529	hsa-miR-586	CLIP-seq
MIRT2166492	hsa-miR-590-3p	CLIP-seq
MIRT2166493	hsa-miR-598	CLIP-seq
MIRT2166495	hsa-miR-626	CLIP-seq
MIRT2468946	hsa-miR-633	CLIP-seq
MIRT1925034	hsa-miR-663	CLIP-seq
MIRT2468947	hsa-miR-889	CLIP-seq
MIRT2166497	hsa-miR-935	CLIP-seq
MIRT763494	hsa-miR-3065-5p	CLIP-seq
MIRT1925019	hsa-miR-548a-5p	CLIP-seq
MIRT1925020	hsa-miR-548ab	CLIP-seq
MIRT1925021	hsa-miR-548ak	CLIP-seq
MIRT1925022	hsa-miR-548b-5p	CLIP-seq
MIRT1925023	hsa-miR-548c-5p	CLIP-seq
MIRT1925024	hsa-miR-548d-5p	CLIP-seq
MIRT1925025	hsa-miR-548h	CLIP-seq
MIRT1925026	hsa-miR-548i	CLIP-seq
MIRT1925027	hsa-miR-548j	CLIP-seq
MIRT1925030	hsa-miR-548w	CLIP-seq
MIRT1925031	hsa-miR-548y	CLIP-seq
MIRT1925032	hsa-miR-559	CLIP-seq

Show/Hide all (47)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0001676	Process	Long-chain fatty acid metabolic process	IBA
GO:0001676	Process	Long-chain fatty acid metabolic process	IMP	22633490
GO:0001676	Process	Long-chain fatty acid metabolic process	ISS
GO:0004467	Function	Long-chain fatty acid-CoA ligase activity	IBA
GO:0004467	Function	Long-chain fatty acid-CoA ligase activity	IEA
GO:0004467	Function	Long-chain fatty acid-CoA ligase activity	IMP	20219900, 22633490
GO:0004467	Function	Long-chain fatty acid-CoA ligase activity	ISS
GO:0004467	Function	Long-chain fatty acid-CoA ligase activity	TAS
GO:0005515	Function	Protein binding	IPI	29549094
GO:0005524	Function	ATP binding	IEA
GO:0005739	Component	Mitochondrion	IEA
GO:0005741	Component	Mitochondrial outer membrane	IEA
GO:0005741	Component	Mitochondrial outer membrane	TAS
GO:0005777	Component	Peroxisome	IEA
GO:0005778	Component	Peroxisomal membrane	IEA
GO:0005783	Component	Endoplasmic reticulum	IBA
GO:0005783	Component	Endoplasmic reticulum	IDA	14741744, 20605918
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	TAS
GO:0005794	Component	Golgi apparatus	IDA	20605918
GO:0005811	Component	Lipid droplet	IBA
GO:0005811	Component	Lipid droplet	IDA	14741744, 21498505
GO:0005886	Component	Plasma membrane	IBA
GO:0006629	Process	Lipid metabolic process	IEA
GO:0006631	Process	Fatty acid metabolic process	IEA
GO:0006631	Process	Fatty acid metabolic process	TAS
GO:0016020	Component	Membrane	HDA	19946888
GO:0016020	Component	Membrane	IEA
GO:0016874	Function	Ligase activity	IEA
GO:0019901	Function	Protein kinase binding	IPI	20605918
GO:0019904	Function	Protein domain specific binding	IPI	20605918
GO:0030182	Process	Neuron differentiation	IBA
GO:0031956	Function	Medium-chain fatty acid-CoA ligase activity	IEA
GO:0034379	Process	Very-low-density lipoprotein particle assembly	IMP	18003621
GO:0035336	Process	Long-chain fatty-acyl-CoA metabolic process	IBA
GO:0035338	Process	Long-chain fatty-acyl-CoA biosynthetic process	TAS
GO:0042998	Process	Positive regulation of Golgi to plasma membrane protein transport	IMP	20605918
GO:0044539	Process	Long-chain fatty acid import into cell	IDA	20219900
GO:0047676	Function	Arachidonate-CoA ligase activity	IEA
GO:0047676	Function	Arachidonate-CoA ligase activity	ISS
GO:0048471	Component	Perinuclear region of cytoplasm	IDA	14741744, 20605918
GO:0051047	Process	Positive regulation of secretion	IMP	18003621
GO:0090433	Function	Palmitoyl-CoA ligase activity	TAS
GO:0120515	Function	Fatty acid-CoA ligase activity	IEA
GO:2001247	Process	Positive regulation of phosphatidylcholine biosynthetic process	IMP	18003621

MIM	HGNC	e!Ensembl
602371	3570	ENSG00000123983

O95573

Protein name

Fatty acid CoA ligase Acsl3 (Arachidonate--CoA ligase) (EC 6.2.1.15) (Long-chain acyl-CoA synthetase 3) (LACS 3) (Long-chain-fatty-acid--CoA ligase 3) (EC 6.2.1.3) (Medium-chain acyl-CoA ligase Acsl3) (EC 6.2.1.2)

Protein function

Acyl-CoA synthetases (ACSL) activates long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:22633490). Required for the incorporation of fatty acids into phosphatidylcholine, the major phospholi

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00501	AMP-binding	113 → 587	AMP-binding enzyme	Family

Sequence

MNNHVSSKPSTMKLKHTINPILLYFIHFLISLYTILTYIPFYFFSESRQEKSNRIKAKPV
NSKPDSAYRSVNSLDGLASVLYPGCDTLDKVFTYAKNKFKNKRLLGTREVLNEEDEVQPN
GKIFKKVILGQYNWLSYEDVFVRAFNFGNGLQMLGQKPKTNIAIFCETRAEWMIAAQACF
MYNFQLVTLYATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGK
PPTWSEFPKGIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMIS
HSNIIAGITGMAERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQ
SSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQI
SKGRNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTES
AGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMGYY
KNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAA
LKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNSCEMENEVLK
VLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMYGRK

Sequence length

720

Interactions

View interactions

	KEGG		Reactome
	Fatty acid biosynthesis Fatty acid degradation Metabolic pathways Fatty acid metabolism PPAR signaling pathway Peroxisome Ferroptosis Thermogenesis Adipocytokine signaling pathway		Intracellular metabolism of fatty acids regulates insulin secretion Synthesis of very long-chain fatty acyl-CoAs

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ASTHMA	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OROPHARYNX CANCER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (24)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
Adenocarcinoma of Lung	Associate	37072786, 39323079	★★★★★ ★☆☆☆☆ Found in Text Mining only
Asthma	Associate	19221603	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Breast Neoplasms	Associate	29450800	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Associate	37248280, 37957550, 39179766	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Non Small Cell Lung	Associate	33030783	★★★★★ ★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Associate	36081434	★★★★★ ★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Associate	36129915	★★★★★ ★☆☆☆☆ Found in Text Mining only
Death Sudden Cardiac	Associate	22661490	★★★★★ ★☆☆☆☆ Found in Text Mining only
Fibrosarcoma	Associate	29450800	★★★★★ ★☆☆☆☆ Found in Text Mining only
Hepatitis C	Associate	18003621	★★★★★ ★☆☆☆☆ Found in Text Mining only
Inflammation	Associate	26016511	★★★★★ ★☆☆☆☆ Found in Text Mining only
Intervertebral Disc Degeneration	Associate	38492610	★★★★★ ★☆☆☆☆ Found in Text Mining only
Leiomyosarcoma	Associate	29450800	★★★★★ ★☆☆☆☆ Found in Text Mining only
Melanoma	Associate	27171439	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Associate	36129915, 39323079	★★★★★ ★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Associate	27171439	★★★★★ ★☆☆☆☆ Found in Text Mining only
Poliomyelitis	Associate	23762027	★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Associate	15556626, 21829708, 28771887	★★★★★ ★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms Castration Resistant	Stimulate	28771887	★★★★★ ★☆☆☆☆ Found in Text Mining only
Rhabdomyosarcoma	Associate	29450800	★★★★★ ★☆☆☆☆ Found in Text Mining only
Sarcoma	Associate	29450800	★★★★★ ★☆☆☆☆ Found in Text Mining only
Squamous Cell Carcinoma of Head and Neck	Associate	38003537	★★★★★ ★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Associate	35182729	★★★★★ ★☆☆☆☆ Found in Text Mining only
Uveal melanoma	Associate	35536719	★★★★★ ★☆☆☆☆ Found in Text Mining only

ACSL3 (acyl-CoA synthetase long chain family member 3)