Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	2177
Gene name Gene Name - the full gene name approved by the HGNC.	FA complementation group D2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	FANCD2
Synonyms (NCBI Gene) Gene synonyms aliases	FA-D2, FA4, FACD, FAD, FAD2, FANCD
Chromosome Chromosome number	3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	3p25.3
Summary Summary of gene provided in NCBI Entrez Gene.	The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FAN

Show/Hide all(14)

SNP ID	Visualize variation	Clinical significance	Consequence
rs112832879	G>A	Pathogenic	Genic downstream transcript variant, splice acceptor variant
rs121917787	C>T	Pathogenic, likely-pathogenic	Missense variant, coding sequence variant, genic downstream transcript variant
rs121917788	C>T	Pathogenic	Stop gained, coding sequence variant, genic downstream transcript variant
rs200118565	G>A,C	Likely-benign, conflicting-interpretations-of-pathogenicity, uncertain-significance	Genic downstream transcript variant, coding sequence variant, synonymous variant
rs201811817	G>A	Pathogenic	Genic downstream transcript variant, splice donor variant
rs374328858	C>T	Pathogenic	Coding sequence variant, genic downstream transcript variant, stop gained
rs748688174	G>A,T	Likely-pathogenic	Splice donor variant, intron variant, genic downstream transcript variant
rs766567785	G>A	Pathogenic	Coding sequence variant, genic downstream transcript variant, missense variant
rs869312805	CCT>-	Likely-pathogenic	Genic downstream transcript variant, inframe deletion, coding sequence variant
rs943009372	G>A	Likely-pathogenic	Splice donor variant
rs1289665675	C>G	Pathogenic, likely-pathogenic	Genic downstream transcript variant, stop gained, coding sequence variant
rs1553607671	->A	Pathogenic	Frameshift variant, coding sequence variant
rs1553608812	A>-	Pathogenic	Frameshift variant, genic downstream transcript variant, coding sequence variant
rs1575723664	->A	Likely-pathogenic	Frameshift variant, coding sequence variant

Show/Hide all(189)

miRTarBase ID	miRNA	Experiments	Reference
MIRT016578	hsa-miR-193b-3p	Microarray	20304954
MIRT052045	hsa-let-7b-5p	CLASH	23622248
MIRT043406	hsa-miR-331-3p	CLASH	23622248
MIRT041043	hsa-miR-505-3p	CLASH	23622248
MIRT039141	hsa-miR-769-5p	CLASH	23622248
MIRT039141	hsa-miR-769-5p	CLASH	23622248
MIRT039141	hsa-miR-769-5p	CLASH	23622248
MIRT717060	hsa-miR-618	HITS-CLIP	19536157
MIRT717059	hsa-miR-34c-3p	HITS-CLIP	19536157
MIRT717058	hsa-miR-759	HITS-CLIP	19536157
MIRT717057	hsa-miR-6870-3p	HITS-CLIP	19536157
MIRT717060	hsa-miR-618	HITS-CLIP	19536157
MIRT717059	hsa-miR-34c-3p	HITS-CLIP	19536157
MIRT717058	hsa-miR-759	HITS-CLIP	19536157
MIRT717057	hsa-miR-6870-3p	HITS-CLIP	19536157
MIRT989021	hsa-miR-103a	CLIP-seq
MIRT989022	hsa-miR-107	CLIP-seq
MIRT989023	hsa-miR-1207-3p	CLIP-seq
MIRT989024	hsa-miR-1285	CLIP-seq
MIRT989025	hsa-miR-1301	CLIP-seq
MIRT989026	hsa-miR-1827	CLIP-seq
MIRT989027	hsa-miR-3153	CLIP-seq
MIRT989028	hsa-miR-3165	CLIP-seq
MIRT989029	hsa-miR-3187-5p	CLIP-seq
MIRT989030	hsa-miR-3622b-5p	CLIP-seq
MIRT989031	hsa-miR-3665	CLIP-seq
MIRT989032	hsa-miR-3672	CLIP-seq
MIRT989033	hsa-miR-3945	CLIP-seq
MIRT989034	hsa-miR-4253	CLIP-seq
MIRT989035	hsa-miR-4261	CLIP-seq
MIRT989036	hsa-miR-4280	CLIP-seq
MIRT989037	hsa-miR-4433	CLIP-seq
MIRT989038	hsa-miR-4459	CLIP-seq
MIRT989039	hsa-miR-4461	CLIP-seq
MIRT989040	hsa-miR-4646-5p	CLIP-seq
MIRT989041	hsa-miR-4668-5p	CLIP-seq
MIRT989042	hsa-miR-4722-5p	CLIP-seq
MIRT989043	hsa-miR-4768-3p	CLIP-seq
MIRT989044	hsa-miR-4793-3p	CLIP-seq
MIRT989045	hsa-miR-5047	CLIP-seq
MIRT989046	hsa-miR-508-5p	CLIP-seq
MIRT989047	hsa-miR-548aa	CLIP-seq
MIRT989048	hsa-miR-548c-3p	CLIP-seq
MIRT989049	hsa-miR-612	CLIP-seq
MIRT989050	hsa-miR-629	CLIP-seq
MIRT989051	hsa-miR-661	CLIP-seq
MIRT989052	hsa-miR-766	CLIP-seq
MIRT989053	hsa-miR-940	CLIP-seq
MIRT989054	hsa-miR-1234	CLIP-seq
MIRT989055	hsa-miR-150	CLIP-seq
MIRT989056	hsa-miR-1913	CLIP-seq
MIRT989057	hsa-miR-324-3p	CLIP-seq
MIRT989058	hsa-miR-520g	CLIP-seq
MIRT989059	hsa-miR-520h	CLIP-seq
MIRT989054	hsa-miR-1234	CLIP-seq
MIRT989055	hsa-miR-150	CLIP-seq
MIRT989056	hsa-miR-1913	CLIP-seq
MIRT989057	hsa-miR-324-3p	CLIP-seq
MIRT989058	hsa-miR-520g	CLIP-seq
MIRT989059	hsa-miR-520h	CLIP-seq
MIRT1993059	hsa-miR-1273f	CLIP-seq
MIRT989026	hsa-miR-1827	CLIP-seq
MIRT1993060	hsa-miR-24	CLIP-seq
MIRT1993061	hsa-miR-3122	CLIP-seq
MIRT989028	hsa-miR-3165	CLIP-seq
MIRT1993062	hsa-miR-3664-3p	CLIP-seq
MIRT989031	hsa-miR-3665	CLIP-seq
MIRT1993063	hsa-miR-3689a-3p	CLIP-seq
MIRT1993064	hsa-miR-3689c	CLIP-seq
MIRT1993065	hsa-miR-3689d	CLIP-seq
MIRT1993066	hsa-miR-3913-5p	CLIP-seq
MIRT1993067	hsa-miR-3919	CLIP-seq
MIRT1993068	hsa-miR-3929	CLIP-seq
MIRT1993069	hsa-miR-4284	CLIP-seq
MIRT1993070	hsa-miR-4419b	CLIP-seq
MIRT989037	hsa-miR-4433	CLIP-seq
MIRT989038	hsa-miR-4459	CLIP-seq
MIRT1993071	hsa-miR-4478	CLIP-seq
MIRT1993072	hsa-miR-4534	CLIP-seq
MIRT1993073	hsa-miR-4649-3p	CLIP-seq
MIRT1993074	hsa-miR-4695-5p	CLIP-seq
MIRT989042	hsa-miR-4722-5p	CLIP-seq
MIRT1993075	hsa-miR-4728-5p	CLIP-seq
MIRT1993076	hsa-miR-4736	CLIP-seq
MIRT1993077	hsa-miR-4756-3p	CLIP-seq
MIRT989043	hsa-miR-4768-3p	CLIP-seq
MIRT1993078	hsa-miR-4802-5p	CLIP-seq
MIRT1993079	hsa-miR-485-5p	CLIP-seq
MIRT1993080	hsa-miR-510	CLIP-seq
MIRT1993081	hsa-miR-512-5p	CLIP-seq
MIRT1993082	hsa-miR-550a	CLIP-seq
MIRT1993083	hsa-miR-607	CLIP-seq
MIRT989053	hsa-miR-940	CLIP-seq
MIRT1993059	hsa-miR-1273f	CLIP-seq
MIRT989055	hsa-miR-150	CLIP-seq
MIRT989026	hsa-miR-1827	CLIP-seq
MIRT2226996	hsa-miR-198	CLIP-seq
MIRT1993060	hsa-miR-24	CLIP-seq
MIRT1993061	hsa-miR-3122	CLIP-seq
MIRT989028	hsa-miR-3165	CLIP-seq
MIRT2226997	hsa-miR-3192	CLIP-seq
MIRT2226998	hsa-miR-3652	CLIP-seq
MIRT1993062	hsa-miR-3664-3p	CLIP-seq
MIRT989031	hsa-miR-3665	CLIP-seq
MIRT1993063	hsa-miR-3689a-3p	CLIP-seq
MIRT1993064	hsa-miR-3689c	CLIP-seq
MIRT1993066	hsa-miR-3913-5p	CLIP-seq
MIRT1993068	hsa-miR-3929	CLIP-seq
MIRT1993069	hsa-miR-4284	CLIP-seq
MIRT2226999	hsa-miR-4300	CLIP-seq
MIRT1993070	hsa-miR-4419b	CLIP-seq
MIRT2227000	hsa-miR-4430	CLIP-seq
MIRT989037	hsa-miR-4433	CLIP-seq
MIRT989038	hsa-miR-4459	CLIP-seq
MIRT1993071	hsa-miR-4478	CLIP-seq
MIRT2227001	hsa-miR-4505	CLIP-seq
MIRT1993072	hsa-miR-4534	CLIP-seq
MIRT2227002	hsa-miR-455-5p	CLIP-seq
MIRT1993073	hsa-miR-4649-3p	CLIP-seq
MIRT2227003	hsa-miR-4661-5p	CLIP-seq
MIRT1993074	hsa-miR-4695-5p	CLIP-seq
MIRT989042	hsa-miR-4722-5p	CLIP-seq
MIRT1993075	hsa-miR-4728-5p	CLIP-seq
MIRT1993076	hsa-miR-4736	CLIP-seq
MIRT989043	hsa-miR-4768-3p	CLIP-seq
MIRT1993079	hsa-miR-485-5p	CLIP-seq
MIRT1993080	hsa-miR-510	CLIP-seq
MIRT1993081	hsa-miR-512-5p	CLIP-seq
MIRT1993082	hsa-miR-550a	CLIP-seq
MIRT2227004	hsa-miR-920	CLIP-seq
MIRT989053	hsa-miR-940	CLIP-seq
MIRT989043	hsa-miR-4768-3p	CLIP-seq
MIRT989024	hsa-miR-1285	CLIP-seq
MIRT989026	hsa-miR-1827	CLIP-seq
MIRT1993061	hsa-miR-3122	CLIP-seq
MIRT989028	hsa-miR-3165	CLIP-seq
MIRT989029	hsa-miR-3187-5p	CLIP-seq
MIRT989030	hsa-miR-3622b-5p	CLIP-seq
MIRT989031	hsa-miR-3665	CLIP-seq
MIRT1993063	hsa-miR-3689a-3p	CLIP-seq
MIRT1993064	hsa-miR-3689c	CLIP-seq
MIRT1993066	hsa-miR-3913-5p	CLIP-seq
MIRT1993068	hsa-miR-3929	CLIP-seq
MIRT989033	hsa-miR-3945	CLIP-seq
MIRT989034	hsa-miR-4253	CLIP-seq
MIRT1993070	hsa-miR-4419b	CLIP-seq
MIRT1993071	hsa-miR-4478	CLIP-seq
MIRT2227002	hsa-miR-455-5p	CLIP-seq
MIRT1993073	hsa-miR-4649-3p	CLIP-seq
MIRT1993075	hsa-miR-4728-5p	CLIP-seq
MIRT1993076	hsa-miR-4736	CLIP-seq
MIRT1993079	hsa-miR-485-5p	CLIP-seq
MIRT989047	hsa-miR-548aa	CLIP-seq
MIRT989048	hsa-miR-548c-3p	CLIP-seq
MIRT1993082	hsa-miR-550a	CLIP-seq
MIRT989049	hsa-miR-612	CLIP-seq
MIRT989053	hsa-miR-940	CLIP-seq
MIRT989024	hsa-miR-1285	CLIP-seq
MIRT989026	hsa-miR-1827	CLIP-seq
MIRT1993061	hsa-miR-3122	CLIP-seq
MIRT989028	hsa-miR-3165	CLIP-seq
MIRT989029	hsa-miR-3187-5p	CLIP-seq
MIRT989030	hsa-miR-3622b-5p	CLIP-seq
MIRT1993062	hsa-miR-3664-3p	CLIP-seq
MIRT989031	hsa-miR-3665	CLIP-seq
MIRT1993063	hsa-miR-3689a-3p	CLIP-seq
MIRT1993064	hsa-miR-3689c	CLIP-seq
MIRT1993066	hsa-miR-3913-5p	CLIP-seq
MIRT1993068	hsa-miR-3929	CLIP-seq
MIRT989033	hsa-miR-3945	CLIP-seq
MIRT989034	hsa-miR-4253	CLIP-seq
MIRT1993070	hsa-miR-4419b	CLIP-seq
MIRT989037	hsa-miR-4433	CLIP-seq
MIRT989038	hsa-miR-4459	CLIP-seq
MIRT1993071	hsa-miR-4478	CLIP-seq
MIRT2227002	hsa-miR-455-5p	CLIP-seq
MIRT1993073	hsa-miR-4649-3p	CLIP-seq
MIRT1993074	hsa-miR-4695-5p	CLIP-seq
MIRT1993075	hsa-miR-4728-5p	CLIP-seq
MIRT1993076	hsa-miR-4736	CLIP-seq
MIRT989043	hsa-miR-4768-3p	CLIP-seq
MIRT1993079	hsa-miR-485-5p	CLIP-seq
MIRT1993080	hsa-miR-510	CLIP-seq
MIRT1993081	hsa-miR-512-5p	CLIP-seq
MIRT989047	hsa-miR-548aa	CLIP-seq
MIRT989048	hsa-miR-548c-3p	CLIP-seq
MIRT1993082	hsa-miR-550a	CLIP-seq
MIRT989049	hsa-miR-612	CLIP-seq
MIRT989053	hsa-miR-940	CLIP-seq

Show/Hide all(32)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000785	Component	Chromatin	NAS	19965384
GO:0000793	Component	Condensed chromosome	IBA
GO:0000793	Component	Condensed chromosome	IEA
GO:0005515	Function	Protein binding	IPI	12874027, 15115758, 17460694, 18212739, 19609304, 20603015, 20603016, 20603073, 20805509, 35384245, 35512704
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	26323318
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005730	Component	Nucleolus	IDA
GO:0005829	Component	Cytosol	IDA
GO:0006281	Process	DNA repair	IEA
GO:0006974	Process	DNA damage response	IEA
GO:0006974	Process	DNA damage response	IEA
GO:0007129	Process	Homologous chromosome pairing at meiosis	IBA
GO:0007129	Process	Homologous chromosome pairing at meiosis	IEA
GO:0007276	Process	Gamete generation	IEA
GO:0010332	Process	Response to gamma radiation	IDA	12874027
GO:0016604	Component	Nuclear body	IDA
GO:0031573	Process	Mitotic intra-S DNA damage checkpoint signaling	IBA
GO:0034599	Process	Cellular response to oxidative stress	IEA
GO:0036297	Process	Interstrand cross-link repair	IBA
GO:0036297	Process	Interstrand cross-link repair	NAS	19965384
GO:0045589	Process	Regulation of regulatory T cell differentiation	IEA
GO:0048854	Process	Brain morphogenesis	IEA
GO:0050727	Process	Regulation of inflammatory response	IEA
GO:0070182	Function	DNA polymerase binding	IBA
GO:0070182	Function	DNA polymerase binding	IPI	19995904
GO:0097150	Process	Neuronal stem cell population maintenance	IEA
GO:1990391	Component	DNA repair complex	IPI	32269332
GO:1990918	Process	Double-strand break repair involved in meiotic recombination	IBA
GO:2000348	Process	Regulation of CD40 signaling pathway	IEA

MIM	HGNC	e!Ensembl
613984	3585	ENSG00000144554

Protein

UniProt ID

Q9BXW9

Protein name

Fanconi anemia group D2 protein (Protein FACD2)

Protein function

Required for maintenance of chromosomal stability (PubMed:11239453, PubMed:14517836). Promotes accurate and efficient pairing of homologs during meiosis (PubMed:14517836). Involved in the repair of DNA double-strand breaks, both by homologous re

PDB

6VAA , 6VAD , 6VAE , 6VAF , 7AY1 , 7KZQ , 7KZR , 7KZS , 7KZT , 7KZV , 7ZF1 , 8A9J , 8A9K

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF14631	FancD2	1 → 1415	Fanconi anaemia protein FancD2 nuclease	Family

Tissue specificity

TISSUE SPECIFICITY: Highly expressed in germinal center cells of the spleen, tonsil, and reactive lymph nodes, and in the proliferating basal layer of squamous epithelium of tonsil, esophagus, oropharynx, larynx and cervix. Expressed in cytotrophoblastic

Sequence

MVSKRRLSKSEDKESLTEDASKTRKQPLSKKTKKSHIANEVEENDSIFVKLLKISGIILK
TGESQNQLAVDQIAFQKKLFQTLRRHPSYPKIIEEFVSGLESYIEDEDSFRNCLLSCERL
QDEEASMGASYSKSLIKLLLGIDILQPAIIKTLFEKLPEYFFENKNSDEINIPRLIVSQL
KWLDRVVDGKDLTTKIMQLISIAPENLQHDIITSLPEILGDSQHADVGKELSDLLIENTS
LTVPILDVLSSLRLDPNFLLKVRQLVMDKLSSIRLEDLPVIIKFILHSVTAMDTLEVISE
LREKLDLQHCVLPSRLQASQVKLKSKGRASSSGNQESSGQSCIILLFDVIKSAIRYEKTI
SEAWIKAIENTASVSEHKVFDLVMLFIIYSTNTQTKKYIDRVLRNKIRSGCIQEQLLQST
FSVHYLVLKDMCSSILSLAQSLLHSLDQSIISFGSLLYKYAFKFFDTYCQQEVVGALVTH
ICSGNEAEVDTALDVLLELVVLNPSAMMMNAVFVKGILDYLDNISPQQIRKLFYVLSTLA
FSKQNEASSHIQDDMHLVIRKQLSSTVFKYKLIGIIGAVTMAGIMAADRSESPSLTQERA
NLSDEQCTQVTSLLQLVHSCSEQSPQASALYYDEFANLIQHEKLDPKALEWVGHTICNDF
QDAFVVDSCVVPEGDFPFPVKALYGLEEYDTQDGIAINLLPLLFSQDFAKDGGPVTSQES
GQKLVSPLCLAPYFRLLRLCVERQHNGNLEEIDGLLDCPIFLTDLEPGEKLESMSAKERS
FMCSLIFLTLNWFREIVNAFCQETSPEMKGKVLTRLKHIVELQIILEKYLAVTPDYVPPL
GNFDVETLDITPHTVTAISAKIRKKGKIERKQKTDGSKTSSSDTLSEEKNSECDPTPSHR
GQLNKEFTGKEEKTSLLLHNSHAFFRELDIEVFSILHCGLVTKFILDTEMHTEATEVVQL
GPPELLFLLEDLSQKLESMLTPPIARRVPFLKNKGSRNIGFSHLQQRSAQEIVHCVFQLL
TPMCNHLENIHNYFQCLAAENHGVVDGPGVKVQEYHIMSSCYQRLLQIFHGLFAWSGFSQ
PENQNLLYSALHVLSSRLKQGEHSQPLEELLSQSVHYLQNFHQSIPSFQCALYLIRLLMV
ILEKSTASAQNKEKIASLARQFLCRVWPSGDKEKSNISNDQLHALLCIYLEHTESILKAI
EEIAGVGVPELINSPKDASSSTFPTLTRHTFVVFFRVMMAELEKTVKKIEPGTAADSQQI
HEEKLLYWNMAVRDFSILINLIKVFDSHPVLHVCLKYGRLFVEAFLKQCMPLLDFSFRKH
REDVLSLLETFQLDTRLLHHLCGHSKIHQDTRLTQHVPLLKKTLELLVCRVKAMLTLNNC
REAFWLGNLKNRDLQGEEIKSQNSQESTADESEDDMSSQASKSKATEDGEEDEVSAGEKE
QDSDESYDDSD

Sequence length

1451

Interactions

View interactions

	KEGG		Reactome
	Fanconi anemia pathway		Fanconi Anemia Pathway TP53 Regulates Transcription of DNA Repair Genes

Show/Hide Causal Diseases (2)

Disease merge term	Disease name	dbSNP ID	References
Causal Diseases caused by PATHOGENIC or LIKELY PATHOGENIC variants from ClinVar only
Fanconi Anemia	fanconi anemia, Fanconi anemia complementation group D2	rs943009372, rs766567785, rs1559399574, rs112832879, rs374328858, rs201811817, rs121917786, rs1553608812, rs1553607671, rs1468320596, rs121917787, rs1289665675, rs1575723664, rs121917788, rs1575824608	N/A
acute myeloid leukemia	Acute myeloid leukemia	rs112832879	N/A

Show/Hide Unknown Diseases (4)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Alzheimer disease	Alzheimer's disease or family history of Alzheimer's disease	N/A	N/A	GWAS
Breast Cancer	Malignant tumor of breast	N/A	N/A	ClinVar
Hepatoblastoma	hepatoblastoma	N/A	N/A	ClinVar
ovarian cancer	Ovarian cancer	N/A	N/A	ClinVar

Show/Hide Text Mining Associations (91)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Aagenaes syndrome	Associate	29118324
Acromegaly	Associate	40415137
Adenocarcinoma of Lung	Associate	35236309, 35509981, 38104669
Adenomatous Polyposis Coli	Associate	39519399
Adrenocortical Carcinoma	Associate	35500219
Alternating hemiplegia of childhood	Associate	31633027
Anemia Hemolytic	Associate	17308347, 17384638, 19609304, 20456353, 21389083, 23318456, 25071006, 27208205, 27405460, 32269332, 32409752, 36385258, 36894310, 8896563
ATR X syndrome	Associate	31628488
Biliary Tract Neoplasms	Associate	25736055
Breast Diseases	Associate	23440494
Breast Neoplasms	Associate	17333336, 19671671, 21766209, 22952942, 23063585, 23897704, 28386063, 29605812, 30799775
Carcinogenesis	Associate	18475298, 19428384, 23965832, 23993743, 28157704, 32420600, 38104669, 40237267
Carcinogenesis	Inhibit	25176410
Carcinoma Hepatocellular	Associate	20509860, 37599085, 40237267, 40287803
Carcinoma Hepatocellular	Stimulate	37821996
Carcinoma Non Small Cell Lung	Associate	25742788
Carcinoma Renal Cell	Associate	32688345, 36081434
Carcinoma Squamous Cell	Associate	26819410, 29118324, 33883185
Chromosomal Instability	Associate	18475298, 38104669
Chromosome Aberrations	Associate	26083937
Chromosome Breakage	Associate	14673148
Chromosome Disorders	Associate	36543851
Chromosome Fragility	Associate	29394375
Colorectal Neoplasms	Associate	15886296, 25669972
Colorectal Neoplasms Hereditary Nonpolyposis	Associate	36011265
Death	Associate	23897704, 30822218
Death	Stimulate	40237267
Digestive System Neoplasms	Stimulate	40237267
Disease	Associate	12086603
DNA Repair Deficiency Disorders	Associate	37777152
DNA Virus Infections	Associate	16893675, 34748904
Drug Related Side Effects and Adverse Reactions	Associate	21766209, 27399778
Endometrial Neoplasms	Associate	29955143, 38218826
Esophageal Neoplasms	Associate	21279724
Esophageal Squamous Cell Carcinoma	Associate	21279724
Fanconi Anemia	Associate	11750104, 12086603, 12239156, 12393398, 14630800, 15199141, 15314022, 15383454, 15849361, 16116422, 16127171, 16893675, 16916645, 17333336, 17387268 View all (82 more)
Fanconi Anemia	Stimulate	16720839, 18174376, 23993743, 29059323, 38104669
Fanconi Anemia Complementation Group J	Associate	25070891
Focal Epithelial Hyperplasia	Associate	19015634
Fragile Site 16p12	Associate	31180492, 37777152
Gallbladder Neoplasms	Associate	33328484
Genetic Diseases Inborn	Associate	27399778, 29659569
Genomic Instability	Associate	18263878
Glioblastoma	Associate	35962621
Glioma	Associate	25071006, 32484805
Hematologic Diseases	Associate	32106311
Hepatitis B	Associate	37821996
Hereditary Breast and Ovarian Cancer Syndrome	Associate	17333336
Hypogonadism	Associate	33270637
Hypoxia	Inhibit	24688021
Hypoxia Brain	Associate	24688021
Infections	Stimulate	21421559
Leukemia	Associate	15886296
Leukemia Lymphocytic Chronic B Cell	Associate	35845961
Leukemia Myelogenous Chronic BCR ABL Positive	Associate	21203397
Leukemia Myeloid Acute	Associate	15886296
Leukemia T Cell	Associate	17539775
Lung Neoplasms	Associate	26385482
Lymphoma Non Hodgkin	Associate	32484805
Melanoma Cutaneous Malignant	Associate	35232428
Mental Disorders	Associate	39365306
Mesothelioma	Associate	22905093
Microsatellite Instability	Associate	15886296, 34328261
Mitochondrial Diseases	Associate	33514811
Multiple Myeloma	Associate	19934314
Myelodysplastic Syndromes	Associate	15886296
Myocardial Infarction	Associate	38253721
Neoplasm Metastasis	Associate	23897704
Neoplasms	Associate	17387268, 18277096, 18483568, 21389083, 22253870, 23063585, 23897704, 23965832, 24221193, 25071006, 25402475, 26083937, 26848151, 27322732, 27399778 View all (24 more)
Neoplasms	Inhibit	17539775, 25557546
Neoplasms Squamous Cell	Associate	24708616, 32560902
Neurilemmoma	Associate	25071006
Neurotoxicity Syndromes	Associate	21766209
Osteosarcoma	Associate	36814203
Ovarian Diseases	Associate	23063585
Ovarian Neoplasms	Associate	23063585, 30822218, 32180586, 34861889, 39456660
Pancreatic Neoplasms	Associate	15277238
Papillomavirus Infections	Associate	28196964
Precancerous Conditions	Inhibit	18475298
Precancerous Conditions	Associate	33099537
Prostate cancer familial	Associate	29659569
Prostatic Neoplasms	Associate	29659569, 34897998
Rectal Neoplasms	Stimulate	36414988
Shwachman Diamond Syndrome	Associate	17539775
Squamous Cell Carcinoma of Head and Neck	Associate	28678401, 36768994
Squamous Intraepithelial Lesions	Stimulate	29995652
Stomach Neoplasms	Associate	36011265
Triple Negative Breast Neoplasms	Associate	34748904
Urinary Bladder Neoplasms	Associate	25316812, 27399778
Uterine Cervical Neoplasms	Associate	24708616, 29995652
Uveal melanoma	Inhibit	23318456

FANCD2 (FA complementation group D2)