Gene Gene information from NCBI Gene database.
Entrez ID 2123
Gene name Ecotropic viral integration site 2A
Gene symbol EVI2A
Synonyms (NCBI Gene)
EVDAEVI-2AEVI2
Chromosome 17
Chromosome location 17q11.2
miRNA miRNA information provided by mirtarbase database.
337
miRTarBase ID miRNA Experiments Reference
MIRT022670 hsa-miR-124-3p Microarray 18668037
MIRT029616 hsa-miR-26b-5p Microarray 19088304
MIRT609564 hsa-miR-551b-5p HITS-CLIP 23313552
MIRT607267 hsa-miR-8485 HITS-CLIP 23313552
MIRT607266 hsa-miR-329-3p HITS-CLIP 23313552
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
7
GO ID Ontology Definition Evidence Reference
GO:0004888 Function Transmembrane signaling receptor activity NAS 2117566
GO:0005515 Function Protein binding IPI 32296183, 33961781
GO:0005794 Component Golgi apparatus IDA
GO:0005829 Component Cytosol IDA
GO:0005886 Component Plasma membrane IDA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
158380 3499 ENSG00000126860
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P22794
Protein name Protein EVI2A (Ecotropic viral integration site 2A protein homolog) (EVI-2A)
Protein function May complex with itself or/and other proteins within the membrane, to function as part of a cell-surface receptor.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05399 EVI2A 5 231 Ectropic viral integration site 2A protein (EVI2A) Family
Sequence
Sequence length 236
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
4
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ENDOMETRIAL CANCER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
ENDOMETRIAL CARCINOMA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
ENDOMETRIAL NEOPLASM GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
EVI2A-related disorder Benign ClinVar
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References Evidence Score
Carcinoma Renal Cell Associate 32633782, 32733620
★☆☆☆☆
Found in Text Mining only
Endometrial Neoplasms Associate 39401154
★☆☆☆☆
Found in Text Mining only
Intellectual Disability Associate 11468690
★☆☆☆☆
Found in Text Mining only
Leukemia Myeloid Associate 7609078
★☆☆☆☆
Found in Text Mining only
Neoplasms Associate 21505061, 7609078
★☆☆☆☆
Found in Text Mining only
Neurofibroma Associate 11468690
★☆☆☆☆
Found in Text Mining only
Neurofibroma Plexiform Stimulate 20844836
★☆☆☆☆
Found in Text Mining only
Neurofibrosarcoma Stimulate 20844836
★☆☆☆☆
Found in Text Mining only