EREG (epiregulin)

Gene

• Entrez ID: 2069
• Gene name: Epiregulin
• Gene symbol: EREG
• Synonyms (NCBI Gene): EPR, ER, Ep
• Chromosome: 4
• Chromosome location: 4q13.3
• Summary: This gene encodes a secreted peptide hormone and member of the epidermal growth factor (EGF) family of proteins. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT016703	hsa-miR-335-5p	Microarray	18185580
MIRT022139	hsa-miR-124-3p	Microarray	18668037
MIRT437629	hsa-miR-150-5p	Microarray, qRT-PCR	22815788
MIRT437656	hsa-miR-181a-5p	Microarray, qRT-PCR	22815788
MIRT437753	hsa-miR-93-5p	Microarray, qRT-PCR	22815788
MIRT504837	hsa-miR-302f	PAR-CLIP	23446348
MIRT504836	hsa-miR-186-3p	PAR-CLIP	23446348
MIRT504835	hsa-miR-4735-5p	PAR-CLIP	23446348
MIRT437629	hsa-miR-150-5p	PAR-CLIP	23446348
MIRT504834	hsa-miR-532-3p	PAR-CLIP	23446348
MIRT504833	hsa-miR-2116-3p	PAR-CLIP	23446348
MIRT504832	hsa-miR-103a-2-5p	PAR-CLIP	23446348
MIRT504831	hsa-miR-4713-5p	PAR-CLIP	23446348
MIRT504830	hsa-miR-6867-3p	PAR-CLIP	23446348
MIRT504829	hsa-miR-3977	PAR-CLIP	23446348
MIRT504828	hsa-miR-576-5p	PAR-CLIP	23446348
MIRT504827	hsa-miR-629-3p	PAR-CLIP	23446348
MIRT504826	hsa-miR-6885-3p	PAR-CLIP	23446348
MIRT437753	hsa-miR-93-5p	PAR-CLIP	26701625
MIRT437753	hsa-miR-93-5p	PAR-CLIP	26701625
MIRT437753	hsa-miR-93-5p	PAR-CLIP	26701625
MIRT437753	hsa-miR-93-5p	PAR-CLIP	26701625
MIRT437753	hsa-miR-93-5p	PAR-CLIP	26701625
MIRT437753	hsa-miR-93-5p	PAR-CLIP	26701625
MIRT437753	hsa-miR-93-5p	PAR-CLIP	26701625
MIRT437753	hsa-miR-93-5p	PAR-CLIP	26701625
MIRT437753	hsa-miR-93-5p	PAR-CLIP	26701625
MIRT437753	hsa-miR-93-5p	PAR-CLIP	26701625
MIRT437753	hsa-miR-93-5p	PAR-CLIP	26701625
MIRT504837	hsa-miR-302f	PAR-CLIP	23446348
MIRT504836	hsa-miR-186-3p	PAR-CLIP	23446348
MIRT504835	hsa-miR-4735-5p	PAR-CLIP	23446348
MIRT437629	hsa-miR-150-5p	PAR-CLIP	23446348
MIRT504834	hsa-miR-532-3p	PAR-CLIP	23446348
MIRT504833	hsa-miR-2116-3p	PAR-CLIP	23446348
MIRT504832	hsa-miR-103a-2-5p	PAR-CLIP	23446348
MIRT504831	hsa-miR-4713-5p	PAR-CLIP	23446348
MIRT504830	hsa-miR-6867-3p	PAR-CLIP	23446348
MIRT504829	hsa-miR-3977	PAR-CLIP	23446348
MIRT504828	hsa-miR-576-5p	PAR-CLIP	23446348
MIRT504827	hsa-miR-629-3p	PAR-CLIP	23446348
MIRT504826	hsa-miR-6885-3p	PAR-CLIP	23446348
MIRT968613	hsa-miR-1227	CLIP-seq
MIRT968614	hsa-miR-1285	CLIP-seq
MIRT968615	hsa-miR-1297	CLIP-seq
MIRT968616	hsa-miR-1305	CLIP-seq
MIRT968617	hsa-miR-150	CLIP-seq
MIRT968618	hsa-miR-1827	CLIP-seq
MIRT968619	hsa-miR-2114	CLIP-seq
MIRT968620	hsa-miR-23a	CLIP-seq
MIRT968621	hsa-miR-23b	CLIP-seq
MIRT968622	hsa-miR-23c	CLIP-seq
MIRT968623	hsa-miR-26a	CLIP-seq
MIRT968624	hsa-miR-26b	CLIP-seq
MIRT968625	hsa-miR-3127-3p	CLIP-seq
MIRT968626	hsa-miR-3145-5p	CLIP-seq
MIRT968627	hsa-miR-3187-5p	CLIP-seq
MIRT968628	hsa-miR-323-3p	CLIP-seq
MIRT968629	hsa-miR-3622b-5p	CLIP-seq
MIRT968630	hsa-miR-3664-3p	CLIP-seq
MIRT968631	hsa-miR-3671	CLIP-seq
MIRT968632	hsa-miR-3682-5p	CLIP-seq
MIRT968633	hsa-miR-3929	CLIP-seq
MIRT968634	hsa-miR-3945	CLIP-seq
MIRT968635	hsa-miR-4252	CLIP-seq
MIRT968636	hsa-miR-4253	CLIP-seq
MIRT968637	hsa-miR-4419b	CLIP-seq
MIRT968638	hsa-miR-4433	CLIP-seq
MIRT968639	hsa-miR-4459	CLIP-seq
MIRT968640	hsa-miR-4465	CLIP-seq
MIRT968641	hsa-miR-4477b	CLIP-seq
MIRT968642	hsa-miR-4478	CLIP-seq
MIRT968643	hsa-miR-4649-3p	CLIP-seq
MIRT968644	hsa-miR-4695-5p	CLIP-seq
MIRT968645	hsa-miR-4768-3p	CLIP-seq
MIRT968646	hsa-miR-4787-3p	CLIP-seq
MIRT968647	hsa-miR-4793-3p	CLIP-seq
MIRT968648	hsa-miR-485-5p	CLIP-seq
MIRT968649	hsa-miR-486-5p	CLIP-seq
MIRT968650	hsa-miR-490-3p	CLIP-seq
MIRT968651	hsa-miR-498	CLIP-seq
MIRT968652	hsa-miR-548c-3p	CLIP-seq
MIRT968653	hsa-miR-590-3p	CLIP-seq
MIRT968654	hsa-miR-607	CLIP-seq
MIRT968655	hsa-miR-612	CLIP-seq
MIRT968656	hsa-miR-656	CLIP-seq
MIRT968657	hsa-miR-767-3p	CLIP-seq
MIRT968658	hsa-miR-940	CLIP-seq
MIRT968614	hsa-miR-1285	CLIP-seq
MIRT968627	hsa-miR-3187-5p	CLIP-seq
MIRT968655	hsa-miR-612	CLIP-seq
MIRT1921210	hsa-miR-4477a	CLIP-seq
MIRT1921211	hsa-miR-4795-3p	CLIP-seq
MIRT1921212	hsa-miR-4803	CLIP-seq
MIRT968656	hsa-miR-656	CLIP-seq
MIRT968613	hsa-miR-1227	CLIP-seq
MIRT968614	hsa-miR-1285	CLIP-seq
MIRT1987095	hsa-miR-1294	CLIP-seq
MIRT968616	hsa-miR-1305	CLIP-seq
MIRT968618	hsa-miR-1827	CLIP-seq
MIRT968626	hsa-miR-3145-5p	CLIP-seq
MIRT968627	hsa-miR-3187-5p	CLIP-seq
MIRT968630	hsa-miR-3664-3p	CLIP-seq
MIRT968633	hsa-miR-3929	CLIP-seq
MIRT1987096	hsa-miR-410	CLIP-seq
MIRT968635	hsa-miR-4252	CLIP-seq
MIRT968637	hsa-miR-4419b	CLIP-seq
MIRT968638	hsa-miR-4433	CLIP-seq
MIRT968639	hsa-miR-4459	CLIP-seq
MIRT968642	hsa-miR-4478	CLIP-seq
MIRT1987097	hsa-miR-4537	CLIP-seq
MIRT968643	hsa-miR-4649-3p	CLIP-seq
MIRT968644	hsa-miR-4695-5p	CLIP-seq
MIRT1987098	hsa-miR-4722-5p	CLIP-seq
MIRT968645	hsa-miR-4768-3p	CLIP-seq
MIRT968647	hsa-miR-4793-3p	CLIP-seq
MIRT968648	hsa-miR-485-5p	CLIP-seq
MIRT968650	hsa-miR-490-3p	CLIP-seq
MIRT968655	hsa-miR-612	CLIP-seq
MIRT968658	hsa-miR-940	CLIP-seq
MIRT968613	hsa-miR-1227	CLIP-seq
MIRT968614	hsa-miR-1285	CLIP-seq
MIRT2221495	hsa-miR-181a	CLIP-seq
MIRT2221496	hsa-miR-181b	CLIP-seq
MIRT2221497	hsa-miR-181c	CLIP-seq
MIRT2221498	hsa-miR-181d	CLIP-seq
MIRT968618	hsa-miR-1827	CLIP-seq
MIRT2221499	hsa-miR-1915	CLIP-seq
MIRT968619	hsa-miR-2114	CLIP-seq
MIRT968626	hsa-miR-3145-5p	CLIP-seq
MIRT968627	hsa-miR-3187-5p	CLIP-seq
MIRT2221500	hsa-miR-3190	CLIP-seq
MIRT968630	hsa-miR-3664-3p	CLIP-seq
MIRT968631	hsa-miR-3671	CLIP-seq
MIRT968633	hsa-miR-3929	CLIP-seq
MIRT968635	hsa-miR-4252	CLIP-seq
MIRT2221501	hsa-miR-4262	CLIP-seq
MIRT968637	hsa-miR-4419b	CLIP-seq
MIRT968638	hsa-miR-4433	CLIP-seq
MIRT968639	hsa-miR-4459	CLIP-seq
MIRT968642	hsa-miR-4478	CLIP-seq
MIRT2221502	hsa-miR-4491	CLIP-seq
MIRT2221503	hsa-miR-452	CLIP-seq
MIRT968643	hsa-miR-4649-3p	CLIP-seq
MIRT2221504	hsa-miR-4657	CLIP-seq
MIRT2221505	hsa-miR-4676-3p	CLIP-seq
MIRT968644	hsa-miR-4695-5p	CLIP-seq
MIRT1987098	hsa-miR-4722-5p	CLIP-seq
MIRT968645	hsa-miR-4768-3p	CLIP-seq
MIRT968647	hsa-miR-4793-3p	CLIP-seq
MIRT968648	hsa-miR-485-5p	CLIP-seq
MIRT968650	hsa-miR-490-3p	CLIP-seq
MIRT2221506	hsa-miR-548n	CLIP-seq
MIRT2221507	hsa-miR-563	CLIP-seq
MIRT2221508	hsa-miR-576-3p	CLIP-seq
MIRT968655	hsa-miR-612	CLIP-seq
MIRT968657	hsa-miR-767-3p	CLIP-seq
MIRT968658	hsa-miR-940	CLIP-seq
MIRT968618	hsa-miR-1827	CLIP-seq
MIRT968633	hsa-miR-3929	CLIP-seq
MIRT968637	hsa-miR-4419b	CLIP-seq
MIRT968638	hsa-miR-4433	CLIP-seq
MIRT968639	hsa-miR-4459	CLIP-seq
MIRT968642	hsa-miR-4478	CLIP-seq
MIRT2387519	hsa-miR-4635	CLIP-seq
MIRT968643	hsa-miR-4649-3p	CLIP-seq
MIRT968644	hsa-miR-4695-5p	CLIP-seq
MIRT1987098	hsa-miR-4722-5p	CLIP-seq
MIRT2387520	hsa-miR-4753-3p	CLIP-seq
MIRT968645	hsa-miR-4768-3p	CLIP-seq
MIRT2387521	hsa-miR-4768-5p	CLIP-seq
MIRT968648	hsa-miR-485-5p	CLIP-seq
MIRT968658	hsa-miR-940	CLIP-seq
MIRT2437035	hsa-miR-1224-5p	CLIP-seq
MIRT2437036	hsa-miR-127-5p	CLIP-seq
MIRT2437037	hsa-miR-1277	CLIP-seq
MIRT2437038	hsa-miR-1304	CLIP-seq
MIRT2437039	hsa-miR-135a	CLIP-seq
MIRT2437040	hsa-miR-135b	CLIP-seq
MIRT2437041	hsa-miR-141	CLIP-seq
MIRT968617	hsa-miR-150	CLIP-seq
MIRT2221495	hsa-miR-181a	CLIP-seq
MIRT2221496	hsa-miR-181b	CLIP-seq
MIRT2221497	hsa-miR-181c	CLIP-seq
MIRT2221498	hsa-miR-181d	CLIP-seq
MIRT2221499	hsa-miR-1915	CLIP-seq
MIRT2437042	hsa-miR-200a	CLIP-seq
MIRT2437043	hsa-miR-219-1-3p	CLIP-seq
MIRT2437044	hsa-miR-2355-5p	CLIP-seq
MIRT2437045	hsa-miR-3125	CLIP-seq
MIRT2437046	hsa-miR-3157-5p	CLIP-seq
MIRT2437047	hsa-miR-3163	CLIP-seq
MIRT2437048	hsa-miR-33a	CLIP-seq
MIRT2437049	hsa-miR-33b	CLIP-seq
MIRT2437050	hsa-miR-34c-3p	CLIP-seq
MIRT2437051	hsa-miR-3661	CLIP-seq
MIRT2437052	hsa-miR-3662	CLIP-seq
MIRT968630	hsa-miR-3664-3p	CLIP-seq
MIRT968631	hsa-miR-3671	CLIP-seq
MIRT968632	hsa-miR-3682-5p	CLIP-seq
MIRT2437053	hsa-miR-376a	CLIP-seq
MIRT2437054	hsa-miR-376b	CLIP-seq
MIRT2437055	hsa-miR-3907	CLIP-seq
MIRT2437056	hsa-miR-3915	CLIP-seq
MIRT2437057	hsa-miR-3916	CLIP-seq
MIRT2437058	hsa-miR-3928	CLIP-seq
MIRT2437059	hsa-miR-4257	CLIP-seq
MIRT2221501	hsa-miR-4262	CLIP-seq
MIRT2437060	hsa-miR-4420	CLIP-seq
MIRT2437061	hsa-miR-4453	CLIP-seq
MIRT1921210	hsa-miR-4477a	CLIP-seq
MIRT2437062	hsa-miR-4538	CLIP-seq
MIRT2437063	hsa-miR-4633-5p	CLIP-seq
MIRT2437064	hsa-miR-4639-5p	CLIP-seq
MIRT2437065	hsa-miR-4646-5p	CLIP-seq
MIRT2437066	hsa-miR-4666-3p	CLIP-seq
MIRT2437067	hsa-miR-4668-3p	CLIP-seq
MIRT2437068	hsa-miR-4689	CLIP-seq
MIRT2437069	hsa-miR-4691-3p	CLIP-seq
MIRT2437070	hsa-miR-4700-3p	CLIP-seq
MIRT2437071	hsa-miR-4709-3p	CLIP-seq
MIRT2437072	hsa-miR-4755-3p	CLIP-seq
MIRT2437073	hsa-miR-4765	CLIP-seq
MIRT1921211	hsa-miR-4795-3p	CLIP-seq
MIRT1921212	hsa-miR-4803	CLIP-seq
MIRT2437074	hsa-miR-520a-5p	CLIP-seq
MIRT2437075	hsa-miR-525-5p	CLIP-seq
MIRT2437076	hsa-miR-526b	CLIP-seq
MIRT2437077	hsa-miR-532-5p	CLIP-seq
MIRT2437078	hsa-miR-543	CLIP-seq
MIRT2437079	hsa-miR-548q	CLIP-seq
MIRT2437080	hsa-miR-610	CLIP-seq
MIRT2437081	hsa-miR-631	CLIP-seq
MIRT968656	hsa-miR-656	CLIP-seq
MIRT2437082	hsa-miR-873	CLIP-seq
MIRT2437083	hsa-miR-877	CLIP-seq
MIRT1921210	hsa-miR-4477a	CLIP-seq
MIRT1921211	hsa-miR-4795-3p	CLIP-seq
MIRT1921212	hsa-miR-4803	CLIP-seq
MIRT968656	hsa-miR-656	CLIP-seq
MIRT2448934	hsa-miR-1267	CLIP-seq
MIRT968614	hsa-miR-1285	CLIP-seq
MIRT968619	hsa-miR-2114	CLIP-seq
MIRT968627	hsa-miR-3187-5p	CLIP-seq
MIRT968629	hsa-miR-3622b-5p	CLIP-seq
MIRT968630	hsa-miR-3664-3p	CLIP-seq
MIRT968633	hsa-miR-3929	CLIP-seq
MIRT2448935	hsa-miR-3942-5p	CLIP-seq
MIRT968634	hsa-miR-3945	CLIP-seq
MIRT968636	hsa-miR-4253	CLIP-seq
MIRT968637	hsa-miR-4419b	CLIP-seq
MIRT968638	hsa-miR-4433	CLIP-seq
MIRT968639	hsa-miR-4459	CLIP-seq
MIRT968642	hsa-miR-4478	CLIP-seq
MIRT968644	hsa-miR-4695-5p	CLIP-seq
MIRT2448936	hsa-miR-4703-5p	CLIP-seq
MIRT968645	hsa-miR-4768-3p	CLIP-seq
MIRT2448937	hsa-miR-4777-3p	CLIP-seq
MIRT968646	hsa-miR-4787-3p	CLIP-seq
MIRT968648	hsa-miR-485-5p	CLIP-seq
MIRT968652	hsa-miR-548c-3p	CLIP-seq
MIRT968655	hsa-miR-612	CLIP-seq
MIRT968657	hsa-miR-767-3p	CLIP-seq
MIRT968614	hsa-miR-1285	CLIP-seq
MIRT968627	hsa-miR-3187-5p	CLIP-seq
MIRT968652	hsa-miR-548c-3p	CLIP-seq
MIRT968655	hsa-miR-612	CLIP-seq
MIRT2437035	hsa-miR-1224-5p	CLIP-seq
MIRT2525114	hsa-miR-1228	CLIP-seq
MIRT2525115	hsa-miR-1246	CLIP-seq
MIRT2525116	hsa-miR-1258	CLIP-seq
MIRT2525117	hsa-miR-125a-5p	CLIP-seq
MIRT2525118	hsa-miR-125b	CLIP-seq
MIRT2437037	hsa-miR-1277	CLIP-seq
MIRT968614	hsa-miR-1285	CLIP-seq
MIRT2525119	hsa-miR-1301	CLIP-seq
MIRT2437038	hsa-miR-1304	CLIP-seq
MIRT2437039	hsa-miR-135a	CLIP-seq
MIRT2437040	hsa-miR-135b	CLIP-seq
MIRT968617	hsa-miR-150	CLIP-seq
MIRT2221495	hsa-miR-181a	CLIP-seq
MIRT2221496	hsa-miR-181b	CLIP-seq
MIRT2221497	hsa-miR-181c	CLIP-seq
MIRT2221498	hsa-miR-181d	CLIP-seq
MIRT968618	hsa-miR-1827	CLIP-seq
MIRT2525120	hsa-miR-1913	CLIP-seq
MIRT968619	hsa-miR-2114	CLIP-seq
MIRT2437043	hsa-miR-219-1-3p	CLIP-seq
MIRT2525121	hsa-miR-3121-3p	CLIP-seq
MIRT2525122	hsa-miR-3122	CLIP-seq
MIRT2437045	hsa-miR-3125	CLIP-seq
MIRT968626	hsa-miR-3145-5p	CLIP-seq
MIRT2437046	hsa-miR-3157-5p	CLIP-seq
MIRT2525123	hsa-miR-3165	CLIP-seq
MIRT968627	hsa-miR-3187-5p	CLIP-seq
MIRT2525124	hsa-miR-324-3p	CLIP-seq
MIRT2525125	hsa-miR-325	CLIP-seq
MIRT2437048	hsa-miR-33a	CLIP-seq
MIRT2437049	hsa-miR-33b	CLIP-seq
MIRT2437050	hsa-miR-34c-3p	CLIP-seq
MIRT2525126	hsa-miR-3613-3p	CLIP-seq
MIRT968629	hsa-miR-3622b-5p	CLIP-seq
MIRT2525127	hsa-miR-3647-3p	CLIP-seq
MIRT2437051	hsa-miR-3661	CLIP-seq
MIRT968630	hsa-miR-3664-3p	CLIP-seq
MIRT968631	hsa-miR-3671	CLIP-seq
MIRT2525128	hsa-miR-3672	CLIP-seq
MIRT968632	hsa-miR-3682-5p	CLIP-seq
MIRT2525129	hsa-miR-3689a-3p	CLIP-seq
MIRT2525130	hsa-miR-3689c	CLIP-seq
MIRT2525131	hsa-miR-3689d	CLIP-seq
MIRT2525132	hsa-miR-371-5p	CLIP-seq
MIRT2525133	hsa-miR-371b-5p	CLIP-seq
MIRT2437053	hsa-miR-376a	CLIP-seq
MIRT2437054	hsa-miR-376b	CLIP-seq
MIRT2437055	hsa-miR-3907	CLIP-seq
MIRT2525134	hsa-miR-3913-5p	CLIP-seq
MIRT2437056	hsa-miR-3915	CLIP-seq
MIRT2437057	hsa-miR-3916	CLIP-seq
MIRT2525135	hsa-miR-3926	CLIP-seq
MIRT2437058	hsa-miR-3928	CLIP-seq
MIRT968633	hsa-miR-3929	CLIP-seq
MIRT968634	hsa-miR-3945	CLIP-seq
MIRT1987096	hsa-miR-410	CLIP-seq
MIRT968635	hsa-miR-4252	CLIP-seq
MIRT968636	hsa-miR-4253	CLIP-seq
MIRT2437059	hsa-miR-4257	CLIP-seq
MIRT2221501	hsa-miR-4262	CLIP-seq
MIRT2525136	hsa-miR-4266	CLIP-seq
MIRT2525137	hsa-miR-4270	CLIP-seq
MIRT2525138	hsa-miR-4279	CLIP-seq
MIRT2525139	hsa-miR-4297	CLIP-seq
MIRT2525140	hsa-miR-4319	CLIP-seq
MIRT968637	hsa-miR-4419b	CLIP-seq
MIRT2437060	hsa-miR-4420	CLIP-seq
MIRT968638	hsa-miR-4433	CLIP-seq
MIRT2525141	hsa-miR-4441	CLIP-seq
MIRT968639	hsa-miR-4459	CLIP-seq
MIRT2525142	hsa-miR-4461	CLIP-seq
MIRT968642	hsa-miR-4478	CLIP-seq
MIRT2525143	hsa-miR-4494	CLIP-seq
MIRT2525144	hsa-miR-4501	CLIP-seq
MIRT2525145	hsa-miR-4530	CLIP-seq
MIRT2437063	hsa-miR-4633-5p	CLIP-seq
MIRT2387519	hsa-miR-4635	CLIP-seq
MIRT2525146	hsa-miR-4643	CLIP-seq
MIRT968643	hsa-miR-4649-3p	CLIP-seq
MIRT2525147	hsa-miR-466	CLIP-seq
MIRT2525148	hsa-miR-4660	CLIP-seq
MIRT2437066	hsa-miR-4666-3p	CLIP-seq
MIRT2437067	hsa-miR-4668-3p	CLIP-seq
MIRT2525149	hsa-miR-4685-5p	CLIP-seq
MIRT2437068	hsa-miR-4689	CLIP-seq
MIRT2437069	hsa-miR-4691-3p	CLIP-seq
MIRT2525150	hsa-miR-4695-3p	CLIP-seq
MIRT968644	hsa-miR-4695-5p	CLIP-seq
MIRT2437070	hsa-miR-4700-3p	CLIP-seq
MIRT2525151	hsa-miR-4710	CLIP-seq
MIRT2525152	hsa-miR-4717-3p	CLIP-seq
MIRT1987098	hsa-miR-4722-5p	CLIP-seq
MIRT2525153	hsa-miR-4728-5p	CLIP-seq
MIRT2525154	hsa-miR-4732-3p	CLIP-seq
MIRT2525155	hsa-miR-4749-3p	CLIP-seq
MIRT2437072	hsa-miR-4755-3p	CLIP-seq
MIRT2525156	hsa-miR-4761-5p	CLIP-seq
MIRT968645	hsa-miR-4768-3p	CLIP-seq
MIRT2525157	hsa-miR-4773	CLIP-seq
MIRT2525158	hsa-miR-4774-5p	CLIP-seq
MIRT968646	hsa-miR-4787-3p	CLIP-seq
MIRT2525159	hsa-miR-4789-3p	CLIP-seq
MIRT968647	hsa-miR-4793-3p	CLIP-seq
MIRT2525160	hsa-miR-4793-5p	CLIP-seq
MIRT1921211	hsa-miR-4795-3p	CLIP-seq
MIRT2525161	hsa-miR-4802-3p	CLIP-seq
MIRT1921212	hsa-miR-4803	CLIP-seq
MIRT968648	hsa-miR-485-5p	CLIP-seq
MIRT968650	hsa-miR-490-3p	CLIP-seq
MIRT2525162	hsa-miR-490-5p	CLIP-seq
MIRT2525163	hsa-miR-499a-5p	CLIP-seq
MIRT2525164	hsa-miR-5047	CLIP-seq
MIRT2525165	hsa-miR-513c	CLIP-seq
MIRT2525166	hsa-miR-514b-5p	CLIP-seq
MIRT2437074	hsa-miR-520a-5p	CLIP-seq
MIRT2437075	hsa-miR-525-5p	CLIP-seq
MIRT2437077	hsa-miR-532-5p	CLIP-seq
MIRT2437078	hsa-miR-543	CLIP-seq
MIRT2525167	hsa-miR-548a-5p	CLIP-seq
MIRT2525168	hsa-miR-548ab	CLIP-seq
MIRT2525169	hsa-miR-548ak	CLIP-seq
MIRT2525170	hsa-miR-548b-5p	CLIP-seq
MIRT968652	hsa-miR-548c-3p	CLIP-seq
MIRT2525171	hsa-miR-548c-5p	CLIP-seq
MIRT2525172	hsa-miR-548d-5p	CLIP-seq
MIRT2525173	hsa-miR-548h	CLIP-seq
MIRT2525174	hsa-miR-548i	CLIP-seq
MIRT2525175	hsa-miR-548j	CLIP-seq
MIRT2221506	hsa-miR-548n	CLIP-seq
MIRT2437079	hsa-miR-548q	CLIP-seq
MIRT2525176	hsa-miR-548s	CLIP-seq
MIRT2525177	hsa-miR-548w	CLIP-seq
MIRT2525178	hsa-miR-548y	CLIP-seq
MIRT2525179	hsa-miR-559	CLIP-seq
MIRT968654	hsa-miR-607	CLIP-seq
MIRT968655	hsa-miR-612	CLIP-seq
MIRT2525180	hsa-miR-628-3p	CLIP-seq
MIRT2437081	hsa-miR-631	CLIP-seq
MIRT2525181	hsa-miR-640	CLIP-seq
MIRT2525182	hsa-miR-670	CLIP-seq
MIRT968657	hsa-miR-767-3p	CLIP-seq
MIRT2437083	hsa-miR-877	CLIP-seq
MIRT2525183	hsa-miR-888	CLIP-seq
MIRT2525184	hsa-miR-889	CLIP-seq
MIRT968658	hsa-miR-940	CLIP-seq
MIRT2437035	hsa-miR-1224-5p	CLIP-seq
MIRT2525114	hsa-miR-1228	CLIP-seq
MIRT2680259	hsa-miR-1236	CLIP-seq
MIRT2525116	hsa-miR-1258	CLIP-seq
MIRT2525117	hsa-miR-125a-5p	CLIP-seq
MIRT2525118	hsa-miR-125b	CLIP-seq
MIRT2437037	hsa-miR-1277	CLIP-seq
MIRT968614	hsa-miR-1285	CLIP-seq
MIRT2437038	hsa-miR-1304	CLIP-seq
MIRT2437039	hsa-miR-135a	CLIP-seq
MIRT2437040	hsa-miR-135b	CLIP-seq
MIRT968617	hsa-miR-150	CLIP-seq
MIRT2221495	hsa-miR-181a	CLIP-seq
MIRT2221496	hsa-miR-181b	CLIP-seq
MIRT2221497	hsa-miR-181c	CLIP-seq
MIRT2221498	hsa-miR-181d	CLIP-seq
MIRT968618	hsa-miR-1827	CLIP-seq
MIRT2525120	hsa-miR-1913	CLIP-seq
MIRT2221499	hsa-miR-1915	CLIP-seq
MIRT968619	hsa-miR-2114	CLIP-seq
MIRT2437043	hsa-miR-219-1-3p	CLIP-seq
MIRT2437044	hsa-miR-2355-5p	CLIP-seq
MIRT2680260	hsa-miR-24	CLIP-seq
MIRT2525122	hsa-miR-3122	CLIP-seq
MIRT2437045	hsa-miR-3125	CLIP-seq
MIRT968626	hsa-miR-3145-5p	CLIP-seq
MIRT2437046	hsa-miR-3157-5p	CLIP-seq
MIRT2525123	hsa-miR-3165	CLIP-seq
MIRT968627	hsa-miR-3187-5p	CLIP-seq
MIRT2525124	hsa-miR-324-3p	CLIP-seq
MIRT2525125	hsa-miR-325	CLIP-seq
MIRT2437048	hsa-miR-33a	CLIP-seq
MIRT2437049	hsa-miR-33b	CLIP-seq
MIRT2437050	hsa-miR-34c-3p	CLIP-seq
MIRT2525126	hsa-miR-3613-3p	CLIP-seq
MIRT968629	hsa-miR-3622b-5p	CLIP-seq
MIRT2525127	hsa-miR-3647-3p	CLIP-seq
MIRT2437051	hsa-miR-3661	CLIP-seq
MIRT2437052	hsa-miR-3662	CLIP-seq
MIRT968630	hsa-miR-3664-3p	CLIP-seq
MIRT968631	hsa-miR-3671	CLIP-seq
MIRT2525128	hsa-miR-3672	CLIP-seq
MIRT968632	hsa-miR-3682-5p	CLIP-seq
MIRT2525129	hsa-miR-3689a-3p	CLIP-seq
MIRT2525130	hsa-miR-3689c	CLIP-seq
MIRT2525131	hsa-miR-3689d	CLIP-seq
MIRT2525132	hsa-miR-371-5p	CLIP-seq
MIRT2525133	hsa-miR-371b-5p	CLIP-seq
MIRT2437053	hsa-miR-376a	CLIP-seq
MIRT2437054	hsa-miR-376b	CLIP-seq
MIRT2437055	hsa-miR-3907	CLIP-seq
MIRT2525134	hsa-miR-3913-5p	CLIP-seq
MIRT2437056	hsa-miR-3915	CLIP-seq
MIRT2437057	hsa-miR-3916	CLIP-seq
MIRT2525135	hsa-miR-3926	CLIP-seq
MIRT2437058	hsa-miR-3928	CLIP-seq
MIRT968633	hsa-miR-3929	CLIP-seq
MIRT968634	hsa-miR-3945	CLIP-seq
MIRT1987096	hsa-miR-410	CLIP-seq
MIRT968635	hsa-miR-4252	CLIP-seq
MIRT968636	hsa-miR-4253	CLIP-seq
MIRT2437059	hsa-miR-4257	CLIP-seq
MIRT2221501	hsa-miR-4262	CLIP-seq
MIRT2525136	hsa-miR-4266	CLIP-seq
MIRT2525137	hsa-miR-4270	CLIP-seq
MIRT2525138	hsa-miR-4279	CLIP-seq
MIRT2525139	hsa-miR-4297	CLIP-seq
MIRT2525140	hsa-miR-4319	CLIP-seq
MIRT2680261	hsa-miR-4329	CLIP-seq
MIRT968637	hsa-miR-4419b	CLIP-seq
MIRT2437060	hsa-miR-4420	CLIP-seq
MIRT968638	hsa-miR-4433	CLIP-seq
MIRT2525141	hsa-miR-4441	CLIP-seq
MIRT968639	hsa-miR-4459	CLIP-seq
MIRT2525142	hsa-miR-4461	CLIP-seq
MIRT968642	hsa-miR-4478	CLIP-seq
MIRT2221502	hsa-miR-4491	CLIP-seq
MIRT2525143	hsa-miR-4494	CLIP-seq
MIRT2525144	hsa-miR-4501	CLIP-seq
MIRT2525145	hsa-miR-4530	CLIP-seq
MIRT2437063	hsa-miR-4633-5p	CLIP-seq
MIRT2387519	hsa-miR-4635	CLIP-seq
MIRT2525146	hsa-miR-4643	CLIP-seq
MIRT968643	hsa-miR-4649-3p	CLIP-seq
MIRT2221504	hsa-miR-4657	CLIP-seq
MIRT2525147	hsa-miR-466	CLIP-seq
MIRT2437066	hsa-miR-4666-3p	CLIP-seq
MIRT2437067	hsa-miR-4668-3p	CLIP-seq
MIRT2525149	hsa-miR-4685-5p	CLIP-seq
MIRT2437068	hsa-miR-4689	CLIP-seq
MIRT2437069	hsa-miR-4691-3p	CLIP-seq
MIRT2525150	hsa-miR-4695-3p	CLIP-seq
MIRT968644	hsa-miR-4695-5p	CLIP-seq
MIRT2437070	hsa-miR-4700-3p	CLIP-seq
MIRT2437071	hsa-miR-4709-3p	CLIP-seq
MIRT2525152	hsa-miR-4717-3p	CLIP-seq
MIRT1987098	hsa-miR-4722-5p	CLIP-seq
MIRT2525153	hsa-miR-4728-5p	CLIP-seq
MIRT2525154	hsa-miR-4732-3p	CLIP-seq
MIRT2525155	hsa-miR-4749-3p	CLIP-seq
MIRT2437072	hsa-miR-4755-3p	CLIP-seq
MIRT2525156	hsa-miR-4761-5p	CLIP-seq
MIRT2437073	hsa-miR-4765	CLIP-seq
MIRT968645	hsa-miR-4768-3p	CLIP-seq
MIRT2525157	hsa-miR-4773	CLIP-seq
MIRT2525158	hsa-miR-4774-5p	CLIP-seq
MIRT968646	hsa-miR-4787-3p	CLIP-seq
MIRT2525159	hsa-miR-4789-3p	CLIP-seq
MIRT968647	hsa-miR-4793-3p	CLIP-seq
MIRT2525160	hsa-miR-4793-5p	CLIP-seq
MIRT1921211	hsa-miR-4795-3p	CLIP-seq
MIRT2525161	hsa-miR-4802-3p	CLIP-seq
MIRT1921212	hsa-miR-4803	CLIP-seq
MIRT968648	hsa-miR-485-5p	CLIP-seq
MIRT968650	hsa-miR-490-3p	CLIP-seq
MIRT2525162	hsa-miR-490-5p	CLIP-seq
MIRT2525163	hsa-miR-499a-5p	CLIP-seq
MIRT2525165	hsa-miR-513c	CLIP-seq
MIRT2525166	hsa-miR-514b-5p	CLIP-seq
MIRT2437074	hsa-miR-520a-5p	CLIP-seq
MIRT2437075	hsa-miR-525-5p	CLIP-seq
MIRT2437077	hsa-miR-532-5p	CLIP-seq
MIRT2437078	hsa-miR-543	CLIP-seq
MIRT968652	hsa-miR-548c-3p	CLIP-seq
MIRT2437079	hsa-miR-548q	CLIP-seq
MIRT2525176	hsa-miR-548s	CLIP-seq
MIRT2221507	hsa-miR-563	CLIP-seq
MIRT2221508	hsa-miR-576-3p	CLIP-seq
MIRT2680262	hsa-miR-593	CLIP-seq
MIRT968654	hsa-miR-607	CLIP-seq
MIRT968655	hsa-miR-612	CLIP-seq
MIRT2525180	hsa-miR-628-3p	CLIP-seq
MIRT2437081	hsa-miR-631	CLIP-seq
MIRT2525181	hsa-miR-640	CLIP-seq
MIRT2525182	hsa-miR-670	CLIP-seq
MIRT968657	hsa-miR-767-3p	CLIP-seq
MIRT2437082	hsa-miR-873	CLIP-seq
MIRT2437083	hsa-miR-877	CLIP-seq
MIRT2525183	hsa-miR-888	CLIP-seq
MIRT2525184	hsa-miR-889	CLIP-seq
MIRT968658	hsa-miR-940	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
KDM2A	Repression	23074094
NFIL3	Unknown	1620116
WT1	Unknown	17430890

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001525	Process	Angiogenesis	IEA
GO:0001550	Process	Ovarian cumulus expansion	IEA
GO:0001550	Process	Ovarian cumulus expansion	ISS
GO:0001556	Process	Oocyte maturation	IEA
GO:0001556	Process	Oocyte maturation	ISS
GO:0001819	Process	Positive regulation of cytokine production	IDA	10681561
GO:0001819	Process	Positive regulation of cytokine production	IEA
GO:0001819	Process	Positive regulation of cytokine production	ISS
GO:0005154	Function	Epidermal growth factor receptor binding	IBA
GO:0005154	Function	Epidermal growth factor receptor binding	IEA
GO:0005154	Function	Epidermal growth factor receptor binding	ISS
GO:0005154	Function	Epidermal growth factor receptor binding	TAS	10681561
GO:0005515	Function	Protein binding	IPI	9419975, 28988771, 32296183
GO:0005576	Component	Extracellular region	IEA
GO:0005576	Component	Extracellular region	TAS
GO:0005615	Component	Extracellular space	IBA
GO:0005615	Component	Extracellular space	IDA	9556621, 28783046
GO:0005615	Component	Extracellular space	IDA	9337852, 14581411
GO:0005615	Component	Extracellular space	IEA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS	9337852
GO:0007143	Process	Female meiotic nuclear division	IEA
GO:0007143	Process	Female meiotic nuclear division	ISS
GO:0007173	Process	Epidermal growth factor receptor signaling pathway	IBA
GO:0007173	Process	Epidermal growth factor receptor signaling pathway	IDA	9556621, 28783046
GO:0007173	Process	Epidermal growth factor receptor signaling pathway	IEA
GO:0007173	Process	Epidermal growth factor receptor signaling pathway	ISS	9990076
GO:0007267	Process	Cell-cell signaling	IDA	14581411
GO:0008083	Function	Growth factor activity	IBA
GO:0008083	Function	Growth factor activity	IEA
GO:0008284	Process	Positive regulation of cell population proliferation	IBA
GO:0008284	Process	Positive regulation of cell population proliferation	IDA	10681561
GO:0008284	Process	Positive regulation of cell population proliferation	IEA
GO:0008284	Process	Positive regulation of cell population proliferation	ISS
GO:0008285	Process	Negative regulation of cell population proliferation	IEA
GO:0008285	Process	Negative regulation of cell population proliferation	ISS
GO:0009299	Process	MRNA transcription	IDA	10681561
GO:0009653	Process	Anatomical structure morphogenesis	TAS	9337852
GO:0009887	Process	Animal organ morphogenesis	TAS	9337852
GO:0016020	Component	Membrane	IEA
GO:0019221	Process	Cytokine-mediated signaling pathway	IDA	9419975
GO:0030154	Process	Cell differentiation	IEA
GO:0030216	Process	Keratinocyte differentiation	TAS	10681561
GO:0030297	Function	Transmembrane receptor protein tyrosine kinase activator activity	IDA	9556621, 28783046
GO:0030297	Function	Transmembrane receptor protein tyrosine kinase activator activity	IEA
GO:0030669	Component	Clathrin-coated endocytic vesicle membrane	TAS
GO:0030728	Process	Ovulation	IEA
GO:0030728	Process	Ovulation	ISS
GO:0032755	Process	Positive regulation of interleukin-6 production	IEA
GO:0032755	Process	Positive regulation of interleukin-6 production	ISS
GO:0038134	Process	ERBB2-EGFR signaling pathway	IDA	9556621
GO:0038135	Process	ERBB2-ERBB4 signaling pathway	IDA	9556621
GO:0038138	Process	ERBB4-ERBB4 signaling pathway	IDA	9556621
GO:0042060	Process	Wound healing	TAS	12898511
GO:0042327	Process	Positive regulation of phosphorylation	IDA	9419975, 10681561
GO:0042700	Process	Luteinizing hormone signaling pathway	IEA
GO:0042700	Process	Luteinizing hormone signaling pathway	ISS
GO:0043434	Process	Response to peptide hormone	IEA
GO:0043616	Process	Keratinocyte proliferation	IDA	10681561
GO:0045089	Process	Positive regulation of innate immune response	IEA
GO:0045089	Process	Positive regulation of innate immune response	ISS
GO:0045740	Process	Positive regulation of DNA replication	IDA	9337852, 10681561
GO:0045740	Process	Positive regulation of DNA replication	IEA
GO:0045740	Process	Positive regulation of DNA replication	ISS	9990076
GO:0045840	Process	Positive regulation of mitotic nuclear division	IBA
GO:0045840	Process	Positive regulation of mitotic nuclear division	IEA
GO:0045840	Process	Positive regulation of mitotic nuclear division	ISS	9990076
GO:0045860	Process	Positive regulation of protein kinase activity	IDA	14581411
GO:0045892	Process	Negative regulation of DNA-templated transcription	IDA	14581411
GO:0048018	Function	Receptor ligand activity	IDA	9556621, 28783046
GO:0048018	Function	Receptor ligand activity	IEA
GO:0048146	Process	Positive regulation of fibroblast proliferation	IDA	12702554
GO:0048160	Process	Primary follicle stage	IEA
GO:0048160	Process	Primary follicle stage	ISS
GO:0048513	Process	Animal organ development	IEA
GO:0048661	Process	Positive regulation of smooth muscle cell proliferation	IEA
GO:0048661	Process	Positive regulation of smooth muscle cell proliferation	ISS	9990076
GO:0050680	Process	Negative regulation of epithelial cell proliferation	TAS	10681561
GO:0051151	Process	Negative regulation of smooth muscle cell differentiation	IDA	14581411
GO:0051240	Process	Positive regulation of multicellular organismal process	IEA
GO:0051781	Process	Positive regulation of cell division	IEA

Other IDs

• MIM: 602061
• HGNC: 3443
• e!Ensembl: ENSG00000124882

Protein

• UniProt ID: O14944
• Protein name: Proepiregulin [Cleaved into: Epiregulin (EPR)]
• Protein function: Ligand of the EGF receptor/EGFR and ERBB4. Stimulates EGFR and ERBB4 tyrosine phosphorylation (PubMed:9419975). Contributes to inflammation, wound healing, tissue repair, and oocyte maturation by regulating angiogenesis and vascular remodeling a
• PDB: 1K36, 1K37, 5E8D, 5WB7, 7LEN, 7LFR, 7LFS, 8HGP
• Tissue specificity: TISSUE SPECIFICITY: In normal adults, expressed predominantly in the placenta and peripheral blood leukocytes. High levels were detected in carcinomas of the bladder, lung, kidney and colon. {ECO:0000269|PubMed:9337852}.
• Sequence:

  MTAGRRMEMLCAGRVPALLLCLGFHLLQAVLSTTVIPSCIPGESSDNCTALVQTEDNPRV
  AQVSITKCSSDMNGYCLHGQCIYLVDMSQNYCRCEVGYTGVRCEHFFLTVHQPLSKEYVA
  LTVILIILFLITVVGSTYYFCRWYRNRKSKEPKKEYERVTSGDPELPQV

• Sequence length: 169

Pathways

KEGG:

MAPK signaling pathway
ErbB signaling pathway
PI3K-Akt signaling pathway
Colorectal cancer

Reactome:

Signaling by ERBB2
Signaling by ERBB4
SHC1 events in ERBB2 signaling
PI3K events in ERBB4 signaling
SHC1 events in ERBB4 signaling
PIP3 activates AKT signaling
Signaling by EGFR
GRB2 events in EGFR signaling
GAB1 signalosome
SHC1 events in EGFR signaling
EGFR downregulation
GRB2 events in ERBB2 signaling
PI3K events in ERBB2 signaling
EGFR interacts with phospholipase C-gamma
Constitutive Signaling by Aberrant PI3K in Cancer
Inhibition of Signaling by Overexpressed EGFR
RAF/MAP kinase cascade
ERBB2 Regulates Cell Motility
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
ERBB2 Activates PTK6 Signaling
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis
Downregulation of ERBB2 signaling
Extra-nuclear estrogen signaling
Estrogen-dependent nuclear events downstream of ESR-membrane signaling
Signaling by ERBB2 KD Mutants
Signaling by ERBB2 TMD/JMD mutants