Gene Gene information from NCBI Gene database.
Entrez ID 2063
Gene name Nuclear receptor subfamily 2 group F member 6
Gene symbol NR2F6
Synonyms (NCBI Gene)
EAR-2EAR2ERBAL2
Chromosome 19
Chromosome location 19p13.11
miRNA miRNA information provided by mirtarbase database.
519
miRTarBase ID miRNA Experiments Reference
MIRT004232 hsa-miR-346 Microarray 16822819
MIRT018838 hsa-miR-335-5p Microarray 18185580
MIRT027803 hsa-miR-98-5p Microarray 19088304
MIRT049946 hsa-miR-30a-5p CLASH 23622248
MIRT048210 hsa-miR-196a-5p CLASH 23622248
Transcription factors Transcription factors information provided by TRRUST V2 database.
2
Transcription factor Regulation Reference
CREB1 Repression 15955695
ESRRA Repression 15955695
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
30
GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IBA
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IDA 10644740
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IEA
GO:0000785 Component Chromatin ISA
GO:0000978 Function RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
132880 7977 ENSG00000160113
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P10588
Protein name Nuclear receptor subfamily 2 group F member 6 (V-erbA-related protein 2) (EAR-2)
Protein function Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5'-AGGTCA-3' direct or inverted repeats with various spacings which are also recognized by other n
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00105 zf-C4 54 123 Zinc finger, C4 type (two domains) Domain
PF00104 Hormone_recep 195 377 Ligand-binding domain of nuclear hormone receptor Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in heart, placenta, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:10713182}.
Sequence
Sequence length 404
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Nuclear Receptor transcription pathway